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書籍詳細

未契約
書籍名 MRS of the Brain and Neurological Disorders
出版社 先端医療技術研究所
発行日 2000-01-01
著者
  • Akihiro Igata,M.D.(Supervisors)
  • Tetsuhiko Asakura,M.D.(Supervisors)
  • Toshiro Fujimoto,M.D.(Editor & Contributor)
ISBN 084930346x
ページ数 353
版刷巻号
分野
閲覧制限 未契約

「脳神経疾患のMRS」英語版

目次

  • 表紙
  • Contributors
  • Collaborators
  • Preface
  • Words of Recommendation
  • A Message of Congratulation on the Publication of MRS of the Brain and Neurological Disorders
  • Preface to the First Edition
  • CONTENTS
  • Pulse Sequence and Informed Consent
  • Introduction
  • PART I BACKGROUND AND THEORETICAL BASIS
    • Chapter 1 History of MRS
      • 1.1 Magnet and Physical Background
      • 1.2 Major Accomplishments Concerning MRS and MRI
    • Chapter 2 Basic Principles of MRS
      • 2.1 Principles of measurements
        • 2.1.1 RF coil
        • 2.1.2 Localization
          • (1) Single-voxel method
          • (2) Multivoxel method
          • (3) Comparison of the single-voxel and multivoxel methods
        • 2.1.3 Water suppression
        • 2.1.4 Reception of signals and RF detection
      • 2.2 Post-processing
        • 2.2.1 Automatic baseline correction for 31P-CSI
          • (1) Baseline correction
          • (2) Theory
            • Complete spectrum
            • Observed spectrum
            • Baseline-correction spectrum
            • Peak parameters
            • Estimation scheme of values of peak parameters
          • (3) Simulation and discussion
          • (4) Features of the baseline correction
        • 2.2.2 Various post-processing techniques
          • (1) Apodization
          • (2) Phase correction
            • Constant phase correction
            • Linear phase correction
          • (3) Curve fitting
      • 2.3 Factors restricting measurements
        • 2.3.1 The sensitivity of the MRS involving biological samples
          • (1) The nuclear sensitivities of various elements
          • (2) The SNR of MRS studies
          • (3) The upper limit of achievable MRS sensitivities
        • 2.3.2 Various limitation factors
          • (1) Spatial resolution
          • (2) Spatial contamination
          • (3) Temporal resolution
          • (4) Delay time
          • (5) Eddy currents
      • 2.4 Factors affecting the performance
        • 2.4.1 Selection of the RF coil
        • 2.4.2 Fat suppression
        • 2.4.3 Water suppression
        • 2.4.4 Local shim
      • 2.5 Prospects for the future
        • 2.5.1 Improvements in the RF coil technology
        • 2.5.2 Quantification
    • Chapter 3 Understanding Spectra of 31P MRS and 1H MRS
      • 3.1 Major parameters of MRS
        • 3.1.1 Chemical shift
        • 3.1.2 Spin-spin coupling
        • 3.1.3 Relaxation mechanisms
          • (1) Spin-lattice(longitudinal)relaxation
          • (2) Spin-spin(transverse)relaxation
          • (3) Dipole-dipole relaxation mechanism of protons in liquids and variation of T1 and T2 with correlation time(Tc)
        • 3.1.4 Nuclear Overhauser Effect(NOE) and proton decoupling
      • 3.2 31P MRS
        • 3.2.1 Resonance of PME
        • 3.2.2 Resonance of PDE
        • 3.2.3 Phospholipids
        • 3.2.4 Resonance of ATP, Pi, and PCr
      • 3.3 1H MRS
        • 3.3.1 Resonance of NAA(N-acetylaspartate)
        • 3.3.2 Resonance of Cr(creatine and phosphocreatine)
        • 3.3.3 Resonance of Cho(choline containing compounds)
        • 3.3.4 Resonance of lactate
        • 3.3.5 Resonance of NAAG(N-acetylaspartylglutamate)
        • 3.3.6 Resonance of ml(myo-inositol)
        • 3.3.7 Resonance of Glx(glutamate and glutamine)
        • 3.3.8 Resonance of GABA(γ-aminobutyric acid)
    • Chapter 4 MRS of Healthy Individuals
      • 4.1 31P MRS by CSI
        • 4.1.1 Examples of the 31P spectrum of a healthy individual 31P spectra of voxels 1-10
        • 4.1.2 Examples of the 31P spectrum in a healthy individual 31P spectra of voxels 11-13
        • 4.1.3 Examples of the 31P spectrum in a healthy individual 31P spectra of voxels 14 and 15
        • 4.1.4 Examples of the 31P spectrum in a healthy individual 31P spectra obtained by averaging over voxels
        • 4.1.5 Mean ratios of peaks of the 31P spectrum of healthy individuals
        • 4.1.6 Examples of the metabolite image and contour map of a healthy individual
      • 4.2 1H MRS by the single voxel method
        • 4.2.1 Examples of the 1H spectrum of the basal ganglia in a healthy individual
        • 4.2.2 Mean peak ratios in the 1H spectrum of the basal ganglia regions in healthy individuals
        • 4.2.3 Examples of 1H spectra in mesial temporal lobes in a healthy individual
        • 4.2.4 Mean peak ratios in 1H spectra in mesial temporal lobes in healthy individuals
  • PART II CLINICAL APPLICATIONS
    P.87閲覧
    • Chapter 5 Brain Tumors
      • 5.1 Characteristics of the spectrum
        • 5.1.1 31P MRS of brain tumors
          • (1) Quantity of phosphorus compounds
          • (2) Intratumoral pH
          • (3) 31P MRS as a means to monitor therapeutic effects on brain tumors
        • 5.1.2 1H MRS of brain tumors
      • 5.2 Cases(1-21)
        • 1: Pituitary adenoma
        • 2: Pituitary adenoma
        • 3: Meningioma
        • 4: Meningioma
        • 5: Meningioma
        • 6: Neurinoma
        • 7: Epidermoid
        • 8: Astrocytoma(grade I)
        • 9: Astrocytoma(grade II) Evaluations before and after ACNU chemotherapy
        • 10: Astrocytoma(grade III)
        • 11: Astrocytoma(grade III)
        • 12: Astrocytoma(grade III)
        • 13: Astrocytoma(grade IV)
        • 14: Glioblastoma
        • 15: Glioblastoma
        • 16: Oligodendroglioma
        • 17: Metastatic brain tumor(from the rectum)
        • 18: Metastatic brain tumor(from the lung)
        • 19: Metastatic brain tumor(from the lung)
        • 20: Chondrosarcoma
        • 21: Mucocele
      • 5.3 Evaluation of the effects of radiotherapy and chemotherapy on brain tumors
      • 5.4 Evaluation of the effects of radiotherapy for brain tumors on normal brain tissue
    • Chapter 6 Cerebral Infarction
      • 6.1 Characteristics of the spectrum
      • 6.2 Cases(24-35)
        • 24: 5 hours and 1 year after the stroke(Cerebral infarction of the left and right occipital lobes)
        • 25: 2 and 7 days after the stroke(Cerebral infarction of the right temporal and occipital lobes)
        • 26: 2 days after the stroke(Cerebral infarction of the right temporal lobe)
        • 27: 2 days after the stroke(Cerebral infarction of the left frontal and temporal lobes)
        • 28: 3 days after the stroke(Cerebral infarction of the left temporal lobe)
        • 29: 6 days after the stroke(Cerebral infarction of the right frontal and temporal lobes)
        • 30: 7 days after the stroke(Cerebral infarction of the right frontal lobe)
        • 31: 7 days after the stroke(Cerebral infarction in a medial part of the right occipital lobe)
        • 32: 11 weeks after the stroke(Cerebral infarction of the right temporal lobe)
        • 33: 17 months after the stroke(Cerebral infarction of the left temporal lobe)
        • 34: 6 years after the stroke(Cerebral infarction of the left temporal lobe)
        • 35: Course of 31P MRS of cerebral infarction. A summary of 12 cases
    • Chapter 7 Cerebral Arteriovenous Malformation(AVM), Moya Moya Disease
      • 7.1 Characteristics of the spectrum
      • 7.2 Cases(36-40)
        • 36: AVM of the right parietal lobe
        • 37: AVM of the right frontal lobe
        • 38: AVM of the left frontal lobe
        • 39: Moya Moya disease(the blood flow on the right side is maintained due to a bypass operation performed 7 years before)
        • 40: Moya Moya disease
    • Chapter 8 Intracerebral Hemorrhage
      • 8.1 Characteristics of the spectrum
      • 8.2 Cases(41-53)
        • 41: on the day of the stroke(hemorrhage of the left thalamus)
        • 42: 1 day after the stroke(hemorrhage of the right thalamus)
        • 43: 1 day after the stroke(hemorrhage of the left thalamus)
        • 44: 2 days after the stroke(subcortical hemorrhage of the left frontal lobe)
        • 45: 2 days after the stroke(subcortical hemorrhage of the right temporal and parietal lobes)
        • 46: 3 days after the stroke(hemorrhage of the right putamen)
        • 47: 3 days after the stroke(hemorrhage of the right putamen)
        • 48: 4 days after the stroke(hemorrhage of the left putamen)
        • 49: 6 days after the stroke(hemorrhage of the left putamen)
        • 50: 7 days after the stroke(hemorrhage of the right thalamus)
        • 51: 9 days after the stroke(hemorrhage of the right putamen)
        • 52: 11 days after the stroke(hemorrhage of the left thalamus)
        • 53: 14 days after the stroke(hemorrhage of the right putamen)
    • Chapter 9 Dementia
      • 9.1 Characteristics of spectrum
        • 9.1.1 Dementia of Alzheimer type(AD)
        • 9.1.2 Pick's disease
        • 9.1.3 Multi-infarct dementia(MID)
        • 9.1.4 Binswanger's disease
      • 9.2 Cases(54-60)
        • 54: Dementia of Alzheimer type
        • 55: Dementia of Alzheimer type
        • 56: Dementia of Alzheimer type
        • 57-1: Probable Pick's disease(First 31P MRS study at 44 years)
        • 57-2: Probable Pick's disease(Second 31P MRS study at 44 years; 4 months after the first examination)
        • 57-3: Probable Pick's disease(Third 31P MRS study at 45 years; 10 months after the first examination)
        • 57-4: Probable Pick's disease(Fourth 31P MRS study at 45 years; 2 years after the first examination)
        • 57-5: Probable Pick's disease(1H and 31P spectra)
        • 58: Multi-infarct dementia
        • 59: Multi-infarct dementia
        • 60: Binswanger's disease
    • Chapter 10 Other Neurological Disorders
      • 10.1 Characteristics of the spectrum
        • 10.1.1 Multiple sclerosis(MS)
        • 10.1.2 Leukodystrophy
        • 10.1.3 Huntington's disease
      • 10.2 Cases(61-64)
        • 61: Multiple sclerosis
        • 62: Leukodystrophy
        • 63: Huntington's disease
        • 64: Huntington's disease
    • Chapter 11 Epilepsy
      • 11.1 Characteristics of the spectrum
      • 11.2 Cases(65-75)
        • 65: Symptomatic epilepsy
        • 66: Symptomatic epilepsy
        • 67: Symptomatic epilepsy
        • 68: Symptomatic epilepsy
        • 69: Symptomatic epilepsy
        • 70: Symptomatic epilepsy
        • 71: Absence(before and after corpus callosotomy)
        • 72: Symptomatic temporal lobe epilepsy. Complex partial seizures(focus on the left temporal lobe on EEG)
        • 73: Symptomatic temporal lobe epilepsy. Complex partial seizures(focus on the left temporal lobe on EEG)
        • 74: Symptomatic temporal lobe epilepsy. Complex partial seizures(focus on the left temporal lobe on EEG)
        • 75: Generalized seizures
    • Chapter 12 Psychiatric Disorders
      • 12.1 Characteristics of the spectrum
        • 12.1.1 Schizophrenia
        • 12.1.2 Depression
        • 12.1.3 Mania
        • 12.1.4 Alcoholism
      • 12.2 Cases(76-85)
        • 76: Schizophrenia(Disorganized type)
        • 77: Schizophrenia(Disorganized type)
        • 78: Schizophrenia(Disorganized type)
        • 79: Schizophrenia(Catatonic type)
        • 80: Bipolar 1 Disorder, Most Recent Episode Depressed
        • 81: Bipolar 1 Disorder, Most Recent Episode Depressed
        • 82: Bipolar 1 Disorder, Most Recent Episode Manic
        • 83: Alcohol Dependence(History of drinking: about 20 years)
        • 84: Alcohol-induced mood disorder(History of drinking: about 20 years)
        • 85: Alcohol Dependence(History of drinking: about 28 years)
  • Author Index
    P.323閲覧
  • Subject Index
    P.326閲覧

参考文献

表紙

P.3 掲載の参考文献

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  • 92) Collaborator of Jun Hasegawa. Works of Jun Hasegawa, 1996. [Japanese]

PART I BACKGROUND AND THEORETICAL BASIS

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  • 48) Nicklaus, D. J. Use of multiple receive coils for improved signal-to-noise in large field-of-view chemical shift imaging. In:Works in progress:Ninth Annual Scentific Meeting and Exhibition of the Society of Magnetic Resonance in Medicine, New York, USA:SMRM; 1990:1142.
  • 50) Tan, G.; Song, W.; Jesmanowicz, A. et al. Multichannel magnetic resonance spectroscopy. In:Book of proceedings:Twelfth Annual Scientific Meeting of the Society of Magnetic Resonance in Medicine, Vol 1. New York, USA:SMRM; 1993:370.

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  • 3) Gadian, D. G. Nuclear Magnetic Resonance and its Applications to Living Systems. New York:Oxford University Press, 1982.
  • 4) Abraham, R. J.; Fisher,J.; Loftus, P. Introduction to NMR Spectroscopy. Chichester:John Wiley & Sons, 1988.
  • 5) Gunther, H. NMR Spectroscopy. Basic Principles, Concepts, and Applications in Chemistry, Second Edition. Chichester:John Wiley & Sons, 1992.
  • 6) Homans, S. W. A Dictionary of Concepts in NMR. Oxford:Clarendon Press, 1989.
  • 7) Sanders, J. K. M.; Hunter, B. K. Modern NMR Spectroscopy. A Guide for Chemists, Second Edition. Oxford:Oxford University Press, 1993.
  • 8) Laszlo, P. NMR of Newly Accessible Nuclei Volume 1. Chemical and Biochemical Applications. New York:Academic Press, 1983.
  • 9) Freeman, R. Double resonance. In:D. M. Grant, R. K. Harris (Eds). Encyclopedia of Nuclear Magnetic Resonance Volume 3. Chichester:John Wiley & Sons, 1996:pp. 1740-1749.
  • 10) Freeman, R. A Handbook of Nuclear Magnetic Resonance. Longman Scientific & Technical, 1988.
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PART II CLINICAL APPLICATIONS

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  • 2) Asakura, T.; Sasahira, M. Magnetic resonance spectroscopy and chemical shift imaging of the brain. Neurosiences 20:83-101:1994.
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  • 4) Uchimura, K. A clinical study on the energy metabolism and intracellular pH in human brain with cerebral infarction; Detection by 31P-magnetic resonance spectroscopy. Med. J. Kagoshima Univ. 42:223-244; 1990.
  • 9) Asakura, T.; Sasahira, M. Magnetic resonance spectroscopy and chemical shift imaging of the brain. Neurosciences 20:83-101; 1994.
  • 10) Terada, K.; Moriya, N.; Fujimoto, T. et al. 31P chemical shift imaging in cerebral ischemic disorders. Abstracts of 51st Annual Meeting of the Japan Neurosurgical Society. Book 2. Kagoshima p. 198;1992.

P.185 掲載の参考文献

  • 1) Sasahira, M.;Uchimura, K.;Nagayama, T. et al. Evaluation of cerebral blood flow and cerebral phosphorus metabolism in arteriovenous malformations by 123I IMP SPECT and 31P chemical shift imaging. Progress in CT 12:641-649; 1990. [Japanese]
  • 2) Terada, K.; Moriya, N.; Fujimoto, T. et al. 31P chemical shift imaging in cerebral ischemic disorders. Abstracts of 51st Annual Meeting of the Japan Neurosurgical Society. Book 2. Kagoshima p. 198;1992.

P.197 掲載の参考文献

  • 1) Asakura, T.; Sasahira, M. Magnetic resonance spectroscopy and chemical shift imaging of the brain. Neurosciences 20:83-101; 1994.
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