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P.11 掲載の参考文献

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P.22 掲載の参考文献

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• 9) Oriol R, Ye Y, Koren E, Cooper DKC:Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejectionin pig-to-man organ xenotransplantation. Transplantation 56:1433, 1993.

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P.27 掲載の参考文献

• 1) Minanov OP, Itescu S, Neethling FA:Anti-gal IgG antibodies in sera of newborn humans and baboons and its significance in pig xenotransplantation. Transplantation 63:182, 1997.

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• 4) Parker W, Bruno D, Holznecht ZE, Platt JL:Characterization and affinity isolation of xenoreactive human natural antibodies. J. Immunol. 153:3791, 1994.

• 5) McMorrow IM, Comrack CA, Sachs DH, DerSimonian H:Heterogeneity of human anti-pig natural antibodies cross-reactive with the gal (α1,3) galactose epitope. Transplantation 64:501, 1997.

• 6) Yu PB, Holzknecht ZE, Bruno D, Parker W, Platt JL:Modulation of natural IgM binding and complement activation by natural IgG antibodies. J. Immunol. 157:5163, 1996.
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• 7) Bach FH, Ferran C, Hancock WW et al.:Accommodation of vascularized xenografts:Expression of protected genes by donor endothelial cells in a host Th2 cytokine environment. Nature Med. 3:196, 1997.

P.30 掲載の参考文献

• 1) Baldwin III WM, Pruitt SK, Brauer RB, Daha MR, Sanfilippo F:Complement in organ transplantation. Transplantation 59:797, 1995.

• 2) Fremeaux-Bacchi V, Weiss L, Brun P, Kazatchkine MD:Selective disappearance of C3NeF IgG autoantibody in the plasma of a patient with membranoproliferative glomerulonephritis following renal transplantation. Nephrol-Dial-Transplant. 9:811, 1994.
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• 3) Hughes TR, Meri S, Davies M, Williams JD, Morgan BP:Immunocalactelization and characterization of the rat analogue of human CD59 in kidney and glomerular cells. Immunology 80:439, 1993.
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P.39 掲載の参考文献

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• 7) Koyamada N, Miyatake T, Candinas D et al.:Apyrase administration prolongs discordant xenograft survival. Transplantation 62:1739, 1996.
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P.50 掲載の参考文献

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• 33) Kirk AD, Li RA, Kinch MS, Abernethy KA, Doyle C, Bollinger RR:The humanan tiporcine ceIlular repertoire. Transplantation 55:924, 1993.

• 34) Murray AG, Khodadoust MM, Pober JS, Bothwell ALM:Porcine aortic endothelial cells activate human T cells:direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28. Immunity 1:57, 1994.

• 35) Rollins SA, Kennedy SP, Chodera AJ, Elliott EA, Zavoico GB, Matis LA:Evidence that activation of human T cells by porcine endothelium involves direct recognition of porcine SLA and costimulation by porcine ligands for LFA-1 and CD2. Transplantation 57:1709, 1994.

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P.55 掲載の参考文献

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P.62 掲載の参考文献

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• 1) Tsuji K et al.:Successful Xenotransplantation in Rats and Beagles; Use of Long-Term Cryopreserved Porcine Fetal Liver Fragments in Immunocapsule in He-patocyte Transplantation (ed. MitoM, Sawa M) 1997, p202-209. Karger Landes Systems

• 2) 萩原政夫・他:異種ブタ胎児肝組織片を用いた細胞療法の基礎的検討. 今日の移植 10(3):473-475, 1997.

• 3) 萩原政夫・他:免疫隔離カプセルを用いた異種ブタ胎児肝組織片の肝不全改善効果. 今日の移植 10(2):209-212, 1997.
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• 4) Tsuji K et al.:Successful xeno long-term cryopreserved fetal liver fragment trans-plantation from pig to rat or beagle omentum using immunocapsule. Transplant. Proc. 29:3017-3018, 1997.
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• 5) Takebe K et al.:Xenogeneic (pig to rat) fetal liver fragment transplantation using macrocapsules for immunoisolation. Cell Transplantation 5(5S-1):S31-33, 1996.

• 6) Fukuda Y et al.:Effect of pretreatment with fetal liver fragment transplantation on survival of rat liver allograft. Transplant. Proc. 28(3):1364-1365, 1996.
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• 7) Takebe K et al.:Xenogeneic fetal liver fragment transplantation with macrocapsule is beneficial therapy for acute liver failure in rats. Transplant. Proc. 28(2):701-702, 1996.
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• 8) Hagihara M et al.:Immunohistochemical study of isogeneic fetal liver fragment transplants in rats. Transplant. Proc. 26(6):3499, 1994.
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• 9) Shimura T et al.:Analysis of survival of allogeneic fetal liver fragments in rats. Cell Transplant. 4(suppl. 1):S45-47, 1995.

• 10) Hagihara M et al.:Iso and xeno fetal liver transplant therapy for the treatment of acute chronic liver failure in rats. Cell Transplant. 3(suppl. 1):S29-30, 1994.

• 11) Takebe K et al.:Fetal liver fragment transplantation for acute and chronic liver failure in rats. Transplant. Proc. 26(4):2239, 1994.
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• 12) Hagihara M et al.:Effects of iso and xeno fetal liver fragments transplantation on acute and chronic liver failure in rats. Cell Transplant. 3(4):283-290, 1994.
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• 13) Shimura T et al.:Beneficial effect of xenogeneic fetal liver fragment transplantation into a heterotopic subctaneous omentum in acute liver failure in rats. Transplant. Proc. 26(3):1330, 1994.

• 14) 平賀聖悟・他:ラ島細胞移植による糖尿病の治療. 今日の移植 10(2):213-218, 1997.
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P.67 掲載の参考文献

• 1) Tsuji K et al.:Can fetal xeno whole-organ (heart, lung, kidney and liver) grafts escape from hyperacute rejection in experimental discordant combinations as compared with adult xenografts. Transplant. Proc. 29:3022-3023, 1997.
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• 2) Hiraga S et al.:Transplantation of porcine fetal organs to discordant canine recipients. Transplant. Proc. 28(3):1406-1409, 1996.
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• 3) Kanai N, Hagihara M, Tsuji K:unpublished paper.

P.68 掲載の参考文献

• 1) Tsuji K et al.:Studies of xeno tissue typing:Xeno MLR and southern blotting using HLA, C4A, Bf nd SLA cDNA probes and TCRV-β clonotyping. Transplant. Proc. 29:3019-3021, 1997.

• 2) Hagihara M et aL:T-Cell clonotype assay as immunological monitoring in renal and bone marrow transplantations. Transplant. Proc. 29:716-718, 1997.
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• 3) Sato T et al.:Xeno-tissue typing (southern blot and xeno MLR) in humans, monkeys, pigs, and beagles using HLA, SLA, C4A, and Bf cDNA probes. Transplant. Proc. 28(3):1404-1405, 1996.
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• 4) Tsuji K et al.:Allo/xeno histocompatibility and transplantation immunology. Biology of Pregnancy. (eds. Nakayama T, Makino T), 7th Lake Shirakaba Conference, 1995.

• 5) Sato T et al.:Xeno tissue typing using HLA-DR B1 and SLA-DRB DNA southern hybridization and xenogeneic mixed lymphocyte reactions between swine and humans. Transplant. Proc. 27(1):693-695, 1995.

• 6) Hagihara M et al.:Porcine histocompatibility matching test using HLA class II DNA southern hybridization. Transplant. Proc. 26(4):1869, 1994.
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P.69 掲載の参考文献

• 1) Lee CJ, 辻 公美:HLA II transgenic pigs. 今日の移植 10(3):477-481, 1997.

• 2) Lee CJ, Tsuji K et al.:unpublished data.

• 3) Hagihara M et al.:Xenogeneic iso-skin graft and mixed lymphocyte reaction studies using HLA-DP transgenic mice. Transplant. Immunology 4:220-226, 1996.
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• 4) 萩原政夫・他:HLA-DP, DQ トランスジェニックマウスを用いたskin graftおよび MLRの検討. Organ Biology 1(2):84-92, 1994.
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• 5) Hagihara M et al.:Mixed lymphocyte reaction and skin graft using HLA-DP and DQ transgenic mice. Transplant. Proc. 26(4):1868, 1994.
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• 6) Tsuji K et al.:The role of HLA class II antigens/genes in xenogeneic iso, allo and xeno transplantation. Transpl. 26(4):2441-2443, 1994.

• 7) Hagihara M et aL:MLR and skin graft studies in xenogeneic iso-, allo-, and xeno-combinations using HLA-DP and-DQ transgenic mice. Transplant. Proc. 26(2):967-968, 1994.
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• 8) Tsuji K et al.:Role of HLA-DP antigen in xenogeneic iso-skin grafts using transgenic mice. Transplant. Proc. 25(1):136-137, 1993.