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I. 診断の進め方・鑑別診断

P.5 掲載の参考文献

• 1) Parkinson J:An Essay on the Shaking Palsy. Sherwood, Neely & Jones, London, 1817 (豊倉康夫, 萬年 徹, 高須俊明ほか:Parkinson病の原著と全訳, 三共, 東京, 1974)

P.24 掲載の参考文献

• 1) 水野美邦:Parkinson病, VIII症候, 神経精神疾患モノグラフシリーズ10 (塚越廣ら編) 星和書店, 東京, p.88, 1984.

• 2) Parkinson J:An Essay on the Shaking Palsy. Sherwood, Neely & Jones, London, 1817 (豊倉康夫, 萬年徹, 高須俊明, 他:Parkinson病の原著と全訳, 三共, 東京, 1974)

• 3) 豊倉康夫, 黒岩義五郎, 島田康夫:異常運動疾患アンケート調査集計結果-全国24施設における病院統計-厚生省特定疾患・異常運動疾患調査研究班, p.3-57, 1975.

• 4) Hoehn MM and Yahr MD:Parkinsonism:onset, progression and mortality. Neurology (Minneap.) 17:427-442, 1967.

• 5) 平山惠造, 河村満:Parkinson病の症候学, 運動障害 治療 62:1741-1745, 1980

• 6) 当間忍:Parkinson病の症候論.内科 Mook No.23, パーキンソン病とパーキンソン症候群 (阿部正和ら編) 金原出版, 東京, p. 6-66, 1984.

• 7) Martin WE, Loewenson RB, Resch JA:Parkinson's disease. Clinical analysis of 100 patients. Neurology 23:783-789, 1973.
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• 8) Wilson SAK:Disorders of motility and of muscle tone, with special reference to the corpus striatum. Lancet 2:1-10, 1925.

• 9) Brock S and Wechsler IS:Loss of the righting reflex in man with special reference to paralysis agitans. Arch Neurol Psychiat 17:12-17,1927.

• 10) Reichert WH, Doolittle J and McDowell FH:Vestibular dysfunction in Parkinson disease. Neurology (N. Y.) 32:1133-1138, 1982.

• 11) Corin MS, Elizan TS and Bender MB:Oculomotor function in patients with Parkinson's disease. J Neurol Sci 15:251-265, 1972.
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• 12) Eadie MJ, Tyrer JH:Radiological abnormalities of the upper part of the alimentary tract in parkinsonism. Aust Ann Med 14:23-27, 1965.
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• 13) Gibberd FB, Gleeson JA, Gossage AAR, Wilson RSE:Oesophageal dilatation in Parkinson's disease. J Neurol Neurosurg Psychiatry 37:938-940. 1974.

• 14) 平山惠造, 千田富義, 横地正之:局所姿勢反射. 脳神経 29:710-713, 1977.

• 15) 原一, 若山吉弘, 川瀬譲:Parkinson病患者に見られた painful dystonic foot response の臨床的解析. 臨床神経 29:1101-105, 1989.

• 16) 宇尾野公義:Parkinson病と自律神経症状. 神経内科 14:101-108, 1981.

• 17) Rajput AH and Rozdilsky B:Dysautonomia in Parkinsonism:a clinicopathological study. J Neurol Neurosurg Psychiat 39:1092-1100, 1976.
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• 18) Elliott K, cote LJ, Frewin DB and Downey JA:Vascular responses in the hands of Parkinson's disease patients. Neurology 24:857-862, 1974.

• 19) Mayeux R, Stern Y, Rosen J and Leventhal J:Depression, intellectual,impairment, and Parkinson disease. Neurology (N. Y.) 31:645-650, 1981.

• 20) Warburton JW:Depressive symptoms in Parkinson patients referred for thalamotomy. J Neurol Neurosurg Psychiat 30:368-370, 1967.
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• 21) Lieberman A, Dziatolowski M, Kupersmith M, Serby M, Goodgold A, Korein J and Goldstein M:Dementia in Parkinson disease. Ann Neurol 6:355-359, 1979.
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• 22) 杉村公也, 山崎義一, 安藤一也:痴呆を伴ったParkinson病-Alzheimer病との合併例について-. 臨床神経学 17:513-518, 1977.

• 23) Boller F, Mizutani T, Roessmann U and Gambetti P:Parkinson disease, dementia, and Alzheimer disease:Clinicopathological correlations. Ann Neurol 7:329-335, 1980.
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• 24) 村橋真, 若山 弘, 渋谷誠二:L-dopaを主体とする抗Parkinson薬長期治療中にみられた幻覚の出現様式について. 神経内科治療 8:657-662, 1991.

• 25) Tanner CM and Goetz CG:CPK values in Parkinson's disease. N Engl J Med 304:1608-1609, 1981.
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• 26) 中村重信, 宮田学, 亀山正邦:不随意運動疾患における血清dopamine-β-hydroxylase, glutamic acid decarboxylase, l-aromatic amino acid decarboxylarse につい て. 臨床神経学 19:511-514, 1979.

• 27) Yamaguchi T, Nagatsu T, Sugimoto T, Matsuura S, Kondo T, Iizuka R and Narabayashi H:Effects of tyrosine administration on serum biopterin in normal controls and patients with Parkinson's disease. Science 219:75-77, 1983.
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• 28) Papeschi R, Molina-Negro P, Sourkes TL and Erba G:The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Neurology 22:1151-1159, 1972.
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• 29) Tabaddor K, Wolfson LI and Sharpless NS:Ventiricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. Neurology 28:1249-1253, 1978.

• 30) 水野美邦:パーキンソン病および脊髄小脳変性症における髄液Methoxyhydroxyphenylene glycolについて. 脳神経 31:309-312, 1979.

• 31) 山田克浩:Parkinson病の脳脊髄液中のdopamine-beta-hydroxylase活性及び3-methoxy-4-hydroxyphenyl ethylene glycol値の動態について. 臨床神経 20:1028-1029, 1980.

• 32) Lovenberg W, Levine RA, Robinson DS, Ebert M, Williams AC and Calne DB:Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease. Science 204:624-626, 1979.
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• 33) 北川達也, 神庭誠, 西川清方, 原田英昭, 頼田孝男, 高橋和郎:パーキンソン病の脳波. 神経内科 17:138-143, 1982.

• 34) Sano I, Gamo T, Kakimoto Y, Taniguchi K, Takesada M and Nishinuma K:Distribution of catechol compounds in human brain. Biochem Biophys Acta 32:586-587, 1959.
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• 35) Ehringer H and Hornykiewicz O:Verteilung von noradrenalin und dopamin (3-hydroxy-tyramin) im gehirn des menschen und ihr verhalten bei erkrankungen des extrapyramidalen systems. Klin Wochenschr 38:1236-1239, 1960.

• 36) 永津俊治:ドーパミンの生合成と代謝. 脳神経 27:1249-1260, 1975.

• 37) Narabayashi H, Kondo T, Hayashi A, Suzuki T and Nagatsu T:L-threo-3, 4-dihydroxy-phenylserine treatment for akinesia and freezing of parkinosonism. Proc Jpn Acad 57, Ser B, 351-354, 1981.

• 38) Araki M, Takagi, Higuchi and Sugita H:Neuroleptic malignant syndrome:Caffeine contracture of single muscle fibers and muscle pathology. Neurology 38:297-301, 1988.
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• 39) Wakayama Y, Nakashima Y, Tanaka K, Mano Y and Ando K:Parkinson's disease with diphasic dyskinesia and early-morning dystonia. Arch Neurol 39:531, 1982.
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• 40) Riley D, Lang AE:Practical application of a low-protein diet for Parkinson's disease. Neurology 38:1026-1031, 1988.
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• 41) 町田仁史, 渋谷誠二, 若山吉弘, 川崎仁志, 山本正彦, 村橋真, 川畑博:神経変性疾患患者における骨粗鬆症および骨折に関する検討. リハビリテーション医学 28:889, 1991.

• 42) 原一, 若山吉弘, 川瀬譲:Parkinson病患者のすくみ足現象に対するL字型杖の検討 (続報) . リハビリテーション医学 25:369, 1988.

• 43) Marttila RJ and Rinne UK:Disability and progression in Parkinson's disease. Acta Neurol Scandinav 56:159-169, 1977.

P.32 掲載の参考文献

• 1) Critchley M:Arteriosclerotic parkinsonism. Brain 52:23-83, 1929.

• 2) Lewis PD:Parkinsonism. Pathology Br Med J 3:690-697, 1971.
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• 3) 東儀英夫, 小川真, 山之内博, 亀山正邦, 朝長正徳:老年者parkinsonismにおける脳動脈硬化の意義. 臨床神経 16:303-310, 1976.

• 4) Chang CM, Yu YL, Ng HY, Leung SY, Fong KY:Vascular peudoparkinsonism. Acta Neurol Scand 86:588-592, 1992.

• 5) Fitz Gerald PM, Jankovic J:Lower body Parkinsonism; Evidence for vascular etiology. Movement Dis 3:249-260, 1989.
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• 6) 岡安裕之, 自見隆弘, 川崎仁志, 川瀬譲, 鈴木光一, 若川吉弘:脳血管障害患者にみられた小刻み歩行の臨床的検討. 第15回日本脳卒中学会総会抄録 p.196, 1990.

• 7) Thajeb P:Gait disorders of multi-infarct dementia. Acta Neurol Scand 87 239-249, 1993.
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• 8) 河合邦幸, 柳務, 錫村明生, 杢野譲次:脳血管性 parkinsonism (vascular parkinsonism) の臨床的特徴. 臨床神経 23:796-803, 1983.

• 9) 豊倉康夫, 黒岩義五郎, 島田康夫:異常運動疾患アンケート調査集計結果-全国24施設における病院統計-. 厚生省特定疾患・異常運動疾患調査研究班 p.3-57, 1975.

• 10) Pollock M, Hornabrook RW:The prevalence, natural history and dementia of Parkinson's disease. Brain 89:429-448, 1966.
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• 11) Jellinger K:Overview of morphological changes in Parkinson's disease. Adv Neurol 45:1-18, 1986.

• 12) 安藤一也:血管性 Parkinsonism. 現代医療 14:659-663, 1982.

• 13) Parkes JD:Parkinson's disease, cerebral arteriosclerosis, and senile dementia. Q J Med 169:49-61, 1974.
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P.40 掲載の参考文献

• 1) Ayd FJ:A survey of drug-induced extrapyramidal reactions. JAMA 175:1054-1060, 1961.
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• 2) 赤嶺俊彦:Drug-induced Parkinsonism に関する臨床・疫学的研究. 鹿児島大学 医学雑誌 43:109-123, 1991.

• 3) 葛原茂樹, 幸原伸夫, 大川義弘, 桜井曜子, 山之内博:カルシウム拮克薬flunarizineにより誘発されたParkinsonism の4例. 内科 62, 354-358, 1988.

• 4) 川瀬譲, 自見隆弘, 原一, 若山吉弘:flunarizine hydrochloride投与中にみられたパーキンソニズムの5例. 神経内科治療 6:267-270, 1989.
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• 5) 自見隆弘, 若山吉弘, 岡安裕之:シンナリジンによるパーキンソニズム. 神経内科 38:399-400, 1993.

• 6) Saito T, Ishizawa H, Tsuchiya F, Ozawa H, Takahata N:Neurochemical Findings in the cerebrospinal fluid of schizophrenic patients with tardive dyskinesia and neuroleptic-induced parkinsonism. Jpn J Psychiatr Neurol 40:189-194, 1986.

• 7) Takada M, Kono T, Kitai ST:Flunarizine induces a transient loss of tyrosine hydroxylase immunoreactivity in nigrostriatal neurons. Brain Res 590:311-315, 1992.
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• 8) Micheli FE, Pardal MMF, Giannaula R, Gatto M, Parera IC, Paradiso G, Torres M, Pikielny R, Pardal JF:Movement disorders and depression due to flunarizine and cinnarizine. Movement Disorders 4:139-146, 1989.

P.53 掲載の参考文献

• 1) 横地正之:若年性パーキンソン病I. 神経進歩 23:1048-1059, 1979.

• 2) 横地正之:若年性パーキンソニズム. Annual Review 神経 1990 (後藤文男, 高倉公朋, 木下真男, 柳澤信夫, 清水輝夫編), 中外医学社, p.240-253, 1990.

• 3) Quinn N, Critchley P, Marsden CD:Young onset Parkinson's disease. Mov Disord 2:73-91, 1987.
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• 4) Nygaard TG, Marsden CD, Fahn S:Dopa-responsive dystonia:Long-term treatment response and prognosis. Neurology 41:174-181, 1991.
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• 5) 横地正之:L-dopa療法・年齢別効果-若年性発症例の特異性について. パーキンソン病-病態生理と治療法 (加瀬正夫, 安藤一也編), 金原出版, 東京, p.181-192, 1978.

• 6) Lazzarini AM, Myers RH, Zimmerman TR, Mark MH, Golbe LI, Sage JI, Johnson WG, Duvoisin RC:A clinical genetic study of Parkinson's disease:Evidence for dominant transmission. Neurology 44:499-506, 1994.
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• 7) 近藤喜代太郎:パーキンソン病における遺伝と環境の絡み合い. 脳とパーキンソン病 (永津俊治, 吉田充男, 金沢一郎, 小川紀雄編), 平凡社, p.141-162, 1988.

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• 11) Snow BJ, Okada A, Martin WRW, Duvoisin RJ, Calne DB:PET scanning in doparesponsive dystonia, parkinsonism-dystonia and young-onset parkinsonism. In:Segawa M ed. Hereditary progressive dystonia with marked diurnal fluctuation. London:Parthenon publishing, p181-186, 1993.

• 12) Snow BJ, Nygaard TG, Takahashi H, Calne DB:PET studies of dopa-responsive dystonia and early-onset idiopathic parkinsonism. Ann Neurol 34:733-738, 1993.

• 13) Sawle GV, Leenders KL, Brooks DJ, Harwood G, Lees AJ, Frackowiak RSJ, Marsden C:Dopa-responsive dystonia:[18F]-fluorodopa positron emission tomography. Ann Neurol 30:24-30, 1991.

• 14) Calne DB:Is "Parkinson's disease" one disease? J Neurol Neurosurg Psychiatry 52:18-21, 1989.

• 15) Takahashi H, Calne DB:What is Parkinson's disease? In Parkinson's disease and extrapyramidal disorders, pathophysiology and treatment. New York, John Libbey CIC SRL, p.25-32, 1991.

• 16) 瀬川昌也, 近江一彦. 伊東繁, 青山正征, 早川浩:L-DOPAが著効を呈した小児基底核疾患-著明なる変動を伴った遺伝性進行性基底核疾患-. 診療 24:667-672, 1972.

• 17) Nygaard TG, Marsden CD, Duvoisin RC:Dopa-responsive dystonia. Adv Neurol 50:377-384, 1988.
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• 18) Nygaard TG:Dopa-responsive dystonia, delineation of the clinical syndrome and clues to pathogenesis. Adv Neurol 60:577-585, 1993.
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• 19) Segawa M, Nomura Y:Hereditary progressive dystonia with marked diurnal fluctuation, pathophysiological importance of the age of onset. Adv Neurol 60:568-576, 1993.
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• 20) Takahashi H, Snow BJ, Nygaard TG, Calne DB:Clinical heterogeneity of dopa responsive dystonia:PET observations. Adv Neurol 60:586-590, 1993.
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• 21) 野本正弘, 熊本一郎, 佐野雄二, 中島洋明, 納光弘, 井形昭弘:強い"DOPA-responsive fluctuating dustonia"を呈した幼児期発症例を含む良性の家族性パーキンソン病の一家系. 臨床神経 24:1388, 1984 (抄録).

• 22) Okada A, Nakamura K, Snow BJ, Bhatt MH, Nomoto M, Osame M, Calne DB:PET scan study on the dopaminergic system in a Japanese patient with hereditary progressive dystonia (Segawa's disease); case report, Adv Neurol 60:591-594, 1993.

• 23) Yokochi M:Clinicopathological identification of juvenile parkinsonism in reference to dopa-responsive disorders. In:Segawa M ed. Hereditary progressive dystonia. London, Parthenon publishing, p.37-48, 1992.

• 24) Takahashi H, Ohama E, Suzuki S, Horikawa V, Ishikawa A, Morita T, Tsuji S, Ikuta F:Familial juvenile parkinsonism; clinical and pathologic study in a family. Neurology 44:437-441, 1994.

• 25) Rajput AH, Gibb WRG, Zhong XH, Shannak KS, Kish S, Chang LG, Hornykiewicz O:Dopa-responsive dystonia:pathological and biochemical observations in a case, Ann Neurol 35:396-402, 1994.

• 26) Nygaard TG, Wilhelmsen KC, Risch NJ, Brown DL, Trugman JM, Gilliam TC, Fahn S, Weeks DE:Linkage mapping of dopa-responsive dystonia (DRD) to chromosome 14q. Nature Genet 5:386-391, 1993.
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P.59 掲載の参考文献

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P.64 掲載の参考文献

• 1) 近藤智善, 平山恵造:脳腫瘍とParkinsonism. 内科 Mook No.23 パーキンソン病とパーキンソン症候群 (阿部正和ら編) 金原出版 東京 243-251, 1984.

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• 7) 牧豊, 堀江武, 矢崎光保, 堀田とし子:脳腫瘍による不随意運動に関する考察. 脳神経, 15:740-749, 1963.

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P.69 掲載の参考文献

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• 6) Ward CD, Duvoisin RC, Ince SE, Nutt JD, Eldridge R, Calne DB:Parkinson's disease in 65 pairs of twins and in a set of quadruplets. Neurology 33:815-824, 1983.

• 7) Williams DB, Annegers JF, Kokmen E, O'Brien PC, Kurland LT:Brain injury and neurologic sequelae:A cohort study of dementia, parkinsonism, and amyotrophic lateral sclerosis. Neurology 41:1554-1557, 1991.
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• 8) Lindenberg R:Die Schadigungs mechanismen der Substantia nigra bei Hirntraumen und das Problem des post traumatischen Parkinsonismus. Dtsch Z Nervenheilk 185:637-663, 1964.

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III. 治療の実際

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