書籍詳細

未契約

書籍名	内科セミナーPN3 てんかん
出版社	永井書店
発行日	1980-03-01
著者	織田敏次（編集）阿部裕（編集）中川昌一（編集）滝島任（編集）堀内淑彦（編集）鎮目和夫（編集）古川俊之（編集）祖父江逸郎（編集）内野治人（編集）尾前照雄（編集）
ISBN
ページ数	315
版刷巻号	第1版第2刷
分野	臨床医学：内科脳外/神経内科
シリーズ	内科セミナー
閲覧制限	未契約

内科学の急速な進歩・発展は、細分化と専門化をもたらし、近年、ますますその度を深めております。それに伴い、臨床家に要求される知識の量は急増の一途をたどっており、質的にも知識のlife cycleはますます短縮し、日々新しい医学へと脱皮しているのが現状であります。このことは、専門外の知識・情報について疎遠になりがちなspecialistや、最新の情報を吸収しきれないgeneralistの増加という情況をうみ出しております。内科セミナーは、このような認識のもとに企画された内科治療全書であり、up to dateな知識・情報を、迅速に、かつ総合的に提供して、今日の要求に応えようとするものであります。

表紙
閲覧
執筆者一覧
閲覧
目次
閲覧
1. てんかん研究の歴史的展開
P.1閲覧
- I. てんかんの臨床的研究の歴史的重要事項
- II. てんかんの臨床的研究で最近注目されている事項
- 文献
2. てんかんの基礎理論
P.9閲覧
- §1. 実験てんかん
- §2. てんかん発作誘発の条件
- §3. てんかんと年齢
- §4. 遅発性てんかん
3. てんかんの診断
P.63閲覧
- §1. てんかんの分類と臨床特徴
- §2. てんかんの原因疾患
- §3. てんかんと脳波
4. てんかんの治療と問題点
P.127閲覧
- §1. 脳血管性障害とけいれん発作
- §2. てんかんと外傷
- §3. てんかんと妊娠
- §4. 熱性けいれんとてんかん
- §5. てんかん発作時の救急処置と注意点
5. 抗てんかん薬の臨床
P.209閲覧
- §1. てんかんの薬物療法
- §2. 抗てんかん薬の副作用
6. てんかんの社会的問題点
P.247閲覧
- まえがき
- I. てんかんセンターとその役割
- II. てんかん患児の家庭・教育・生活面における問題点
- III. その他の社会生活面の問題
- 文献
7. てんかんの予後
P.259閲覧
- はじめに
- I. 発作型別予後
- II. 外傷性てんかん
- III. 脳波所見と予後
- IV. 抗けいれん薬中止後の予後
- V. 社会的予後
- VI. 死亡と死因
- おわりに
- 文献
索引
P.281閲覧
奥付
閲覧

参考文献

1. てんかん研究の歴史的展開

P.6 掲載の参考文献

1) Alzheimer, A,:Ein Beitrag zur Pathologischen Anatomie der Epilepsie. Mschr. Psychiatr., 4, 1898.

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3) Foerster, O. and Penfield, W,:The structual basis of traumatic epilepsy and results of radical operation. Brain 53, 99, 1930.

4) Gastaut, H. and Gastaut, J. L,:Computerized Transverse Axial Tomography in Epilepsy. Epilepsia 17:325, 1976.
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5) Gastaut, H,:Dictionary of Epilepsy Part I:Definitions World Health Organization, 1973.

6) Gibbs, F. A., Davis, H. and Lennox, W. G,:The electroencephalogram in epilepsy and in conditions of impaired consciousness. Arch. Neurol. and Psychiatr. 34, 1935.

7) Gibbs, F. A. and Gibbs, E. L,:Atlas of Electroencephalography. Vol. II:Epilepsy. Addison-Wesley, Cambridge, 1952.

8) Hauptoman, A,:Luminal bei Epilepsie. Munch, Med, Wochenschr. 59:1907, 1912.

9) Jackson, J. H,:Selected Writings of John Huhlings Jackson. Vol. I:Epilepsy and epileptiform convulsions. London, 1931.

10) Lennox, W. G. and Cobb, S,:Epilepsy. Saunders, Baltimore, 1928.

11) Lennox, W. G,:The petit mal epilepsies:their treatment with Tridione. JAMA. 129, 1069, 1945.

12) Lennox, W. G,:Epilepsy and Related Disorders. Little-Brown, Boston, 1960.

13) Merritt, H. H. and Putnam, J. T,:Sosium diphenylhydantoinate in the treatment of convulsive disorders. JAMA. 111., 1068, 1938.

14) Penfield, W. and Jasper, H,:Epilepsy and the functional Anatomy of the human Brain. Little-Brown, Boston, 1954.

15) Poter, RJ., Penry, J. K. and Wolf, A. A., Jr,:Simultaneous Documentation of Clinical and Electroencephalographic Manifestations of Epileptic Seizures. Quantitative Analytic Studies in Epilepsy. 253, Raven Press, New York, 1976.

16) Scheibel, M. E, Crandall, P. H. and Scheibel, A. B,:The hippocampaldentate complex in temporal Iobe epilepsy. A Golgi Study. Epilepsia, 15:55, 1974.

17) Spielmeyer, W,:Die Pathogenese des epileptischen Krampfes. Histopathologischen Teil. Z. Neur., 109, 1927.

18) Stevens, J. R., Kodama, H., Lonsbury, B. and Mills, L,:Ultradian characteristics of spontaneous seizure discharges recorded by radio telemetry in man. Electroencephalogr. Clin. Neurophysiol. 31:313, 1971.
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19) Woods, I., Ives, J. and Gloor, P,:Prolonged EEG recordings in patients with generalized epilepsy. Electroencephalogr. Clin. Neurophysiol.39:295, 1975.

2. てんかんの基礎理論

P.20 掲載の参考文献

1) Arnold, P. S., Racine, R. J. and Wise, R. A,:Effects of atropine, reserpine, 6-hydroxydopamine, and handling on seizure development in the rat. Exp Neurol, 40:457, 1973.
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2) Baker, W. W. and Benedict, F,:Influence of increased local cholinergic activity on discharge patterns of hippocampal foci. Electroenceph. Clin. Neurophysioly., 28:499, 1970.

3) Burchfiel, J. L., Duchowsky, M. S. and Duffy, F. H,:Neuronal supersensitivity to acetylcholine induced by kindling in the rat hippocampus. Science, 204:1096, 1979.

4) Callaghan, D. A. and Schmark, W. S,:Neurochemical changes and drug effects in a model of epilepsy in the rat. Neuro. Sci., Abstr. 2:257, 1976.

5) Corcoran, M E., Fibiger, H. C., McCaughran, J.A. et al,:Potentiation of amygdaloid kindling and metrazol induced seizures by 6-hydroxydopamine in rats. Exp. Neurol., 45:118, 1974.
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6) Engel, J. and Sharpless, N. S,:Long-lasting depletion of dopamine in the rat amygdala induced by kindling stimulation. Brain. Res., 136:381, 1977.
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7) Forster, F. M,:Action of acetylcholine on motor cortex. Arch. Neurol. psychiat., 54:391, 1941.

8) Goddard, G. V., McIntyre, D. C. and Leech, C. K,:A permanent change in brain function resulting from daily electical stimulation. Exp. Neurol., 25:295, 1969.

9) Goldensohn, E. S,:Initiation and propagation of epileptogenic foci. In:Adrance in Neurvology,:Vol 11, p. 141. Raven Press, New York, 1975.

10) Hansen, S., Perry, T. L, Wada, J. A. et al,:Brain amino acids in baboons with lightinduced epilepsy. Brain, Res., 50:480, 1973.
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11) 平松緑, 森昭胤:E1系マウスと脳内カテコールアミン. 脳研究会誌, 3:126, 1977.

12) 岩田平太郎, 栗山欣弥:タウリン-その代謝と生理・薬理作用, p. 5, 医歯薬出版, 東京, 1975.

13) Karczmar, A. G., Scudder, C. L. and Richardson, D. L,:Interdisciplinary approach to the study of behavior in related mice types. In:chemical Approach to Brain Function. edited by S. Ehrenpreis and I.J,:Kopin, p. 194, Academic press, New York, 1973.

14) 仮屋哲彦:痙攣の生化学, 現代精神医学大系, 21A, 神経化学I, p. 315, 中山書店, 東京, 1978.

15) 黒川正則, 町山幸輝, 加藤誠, 他:マウス脳の粒子アセチルコリンについて. 神経進歩, 6:537, 1962.

16) MacIntosh, F. C. and Oborin, P. E,:Release of acetylcholine from intact cerebral cortex. Abst. Commun. XIX. International Physiol., Congr., p. 580, 1953.

17) Mason, S. T. and Corcoran, M. E,:Forebrain noradrenaline and metrazol-induced seizures. Life. Sci., 23:167, 1978.
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18) 松田誠, 安部美耶子:シナプトゾームにおけるGABA代謝と痙攣誘発との関係. 神経化学, 20:277, 1977.

19) Matz, D. R., Rolf, L. H. and Brune, G. G,:Serotonin metabolism with idiopathic grand mal seizures. J. Neurol., 219:283, 1978.
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20) McGeer, E. G., Ikeda, H., Asakura, T. et al,:Lack of abnormality in brain aromatic amines in rats and mice susceptible to audiogenic seizure. J. Neurochem., 16:945, 1969.
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21) Meldrum, B. S., Balzano, E., Gadea, M. et al,:Thotic and drug-induced epilepsy in the baboon (papio papio):The effects of isoniazid, thiosemicarbazide, pyridoxine and aminooxyacetic acid. Electroenceph. Clin. Neurophysiol., 29:333, 1970.
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22) Meldrum, B. S,:Epilepsy and γ-aminobutyric acid-mediated inhibition. Int. Rev. Neurobiol., 17:1, 1975.

23) 森昭胤, 小林清史:てんかんII, 病態生理 (2), 「現代精神医学大系」, 11:3, 1977.

24) Nahorski, S. R., Roberts. D.J. and Stewart, G. G,:Some neurochemical aspects of penta-methylenetetrazole convulsive activity in rat brain. J. Neurochem. 17:621, 1970.

25) Naruse, H., Kato, M., Kurokawa, M. et al,:Metabolic effects in a convulsive strain of mouse. J. Neurochem., 5:359, 1960.

26) 長尾卓夫, 藤本明, 大下俊則, 他:てんかん患者における髄液モノアミン代謝物質と環状ヌクレオチド. 脳と神経, 31:1225, 1979.

27) O'Leary, J. L. and Goldring, S,:Science and Epilepsy. p. 201. Raven Press. New York. 1976.

28) 大下俊則:痙攣準備性および全身けいれんと脳内アミン. 精神経誌, 50:519, 1978.

29) 大月三郎, 佐藤光源:てんかんの生化学, 金剛出版. 東京, 1979.

30) Osawa, T., Sato, M. and Wake, A,:Anticonvulsive effects of taurine upon kindled amygdaloid seizure and photically-induced seizures. Folia Psychiat. Neurol. Jap., 31:407, 1977.

31) Papeschi, R., Molina-Negro, P., Sourkes, T. L. et al,:The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Neurology, 22:1151, 1972.
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32) Perry, T. L, Hansen, S. and Kennedy, J,:Amino acids in human epileptogenic foci. Arch. Neurol., 32:752, 1975.
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33) Plum, F., Howse, D. C. and Duffy, T. E,:Metabolic effects of seizures. In:Brain Dysfunction in Metabolic Disorders. edited by Plum, F., p. 141, Raven Press, New York, 1974.

34) Pope, A., Morris, A A, Jasper, H. et al,:Histochemical and action potential studies on epileptogenic areas of cerebral cortex in man and the monkey. Rov. Publ. Ass. Nerv. ment. Dis., 26:218, 1947.

35) Sato, M. and Nakashima, T,:Kindling, sleep, and catecholamines. Canad. J. Neurol. Sci., 2:439, 1975.
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36) Sato, M., Hikasa, N. and Otsuki, S,:Experimental epilepsy, psychosis and dopamine receptor sensitivity. Biol. Psychiat., 14:537, 1979.
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37) 佐藤光源, Wada, J. A,:新しい実験てんかんモデルとしての"kindling" preparation:展望. 脳と神経, 27:257, 1975.

38) 佐藤光源:神経精神疾患の生物学的基礎 (2), 「てんかん」, 神経精神薬理, 1:303, 1979.

39) Schlesinger, K., Boggan, W. and Freedman, D,:Genetics of audiogenic seizures II. Effects of pharmacologic manipulation of brain serotonin, norepinephrine and gamma-aminobutyric acid. Life. Sci., 7:437, 1967.

40) Tapia, R. and Awapara, J. Effects of various substituted hydrazones and hydrazines of pyridoxal-5'-phosphate on brain glutamate decarboxylase. Biochem. Pharmac., 18:145, 1969.

41) Takahashi, R., Nasu, N., Tamura, T. and Kato, T,:Relationship of ammonia and acetylcholine level to brain excitability. J. Neurochem., 7:103, 1961.

42) 友田孝子, 佐藤光源, 日笠尚知, 大月三郎:Biphasic effects-抗けいれん作用とけいれん誘発作用-に関する実験的研究. 脳研究会誌, 4:30, 1978.

43) Tower, D. B. (森昭胤ら訳):てんかんの生化学. 永井書店, 大阪, 1964.

44) Van Gelder, N. M., Sherwin, A. L. and Rasmussen, T,:Amino acid content of epileptogenic human brain:focal versus surrounding regions. Brain Res., 40:385, 1972.
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45) Van Gelder, N. M. and Courtois, A,:Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy. Brain Res., 43:477, 1972.

46) Van Gelder, N. M,:Antagonism by taurine of cobalt induced epilepsy in cat and mouse. Brain Res., 47:152, 1972.

47) Wada, J.A, Osawa, T., Wake, A. et al,:Effects of taurine on kindled amygdaloid seizures in rats, cats, and photosensitive baboons. Epilepsia, 16:229, 1975.
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48) Wada, J. A. and Sato, M,:Generalized convulsive seizure induced by daily electrical stimulation of the amygdala in cats. Neurology, 24:565, 1974.

49) Wada, J. A., Sato, M. and Corcoran, M. E,:Persistent seizure susceptibility and recurrent spontaneous seizures in kindled cats. Epilepsia, 15:465, 1974.
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P.33 掲載の参考文献

1) Gastaut, H. and Tassinari, CA,:Triggering mechanisms in epilepsy-The electrical point of view-. Epilepsia, 7:85, 1966.

2) Melekian, B., Laplane, R. and Debray, P,:Considirations cliniques et statistiques sur les convulsions au cours des deshydrations aigues. Annales de P?diatrie, 34:1494, 1962.

3) Singh, B. M., Gupta, D. R. and Strobos, R. J,:Non-ketotic hyperglycaemia and epilepsia partialis continua. Arch. Neurol., 29:187, 1973.

4) Meldrum, B. S,:Epilepsy and γ-amino butyric acid-mediated inhibition. International Review of Neurobiology, 17, 1975.

5) Lennox-Buchthal, M. A,:Febrile convulsions. EEG clin. Neurophysiol., Supplement, 32:1, 1973.

6) Poire, R,:Hypoglycaemic epilepsy:Clinical, electrographic and biological study during induced hypoglycaemia in man. In The Physiopathogenesis of the Epilepsies. Edited by H. Gastaut, H. Jasper, J. Bancaud, and A. Waltregny, ch 8, p. 75, 1969, Springfields, Illinois:CC. Thomas.

7) Langdon-Down, M. and Brain, W. R,:Times of day in relation to convulsions in epilepsy. Lancet, 1:1029, 1929.

8) Janz, D,:Epilepsy and the sleeping-waking cycle. In Handbook of Clinical Neurology. Edited by P. J. Vinken, and G. W. Bruyn, 15:311, 1974, Amsterdam, North Holland Publishing CO.

9) Christian, W,:Bioelektrische Charakteristik tages-periodisch gebundener Verlaufsformen epileptischer Erkrankungen. Deutsch Zeit Nervenheilk, 181:413, 1960.

10) Jovanovic, V. J,:Das Schlafverhalten der Epileptiker. I. Schlafdauer, Schlaftiefe und Besonderheiten der Schlaf-Periodik. Deutsche Zeitschrift fur Nervenheilkunde, 190:159, 1967.

11) Janz, D. 稲見允昭訳:てんかんの類型と睡眠のタイプ. 精神医学, 17:220, 1975.

12) Gillin, D. D., Jacobs, L. S., Snyder, F. and Henkin, R. I,:Effects of decreased adrenal corticosteroids;changes in sleep in normal subjects and patients with adrenal cortical insufficiency. EEG clin. Neurophysiol., 36:283, 1973.

13) Dunleavy, D. L. F., Oswald, I., Brown, P. and Strong, J. A,:Hyperthyroidism, sleep and growth hormone. EEG clin. Neurophysiol., 36:259, 1974.

14) Harley, R. D., Baird, H. W. and Freeman, R. D,:Self-induced photogenic epilepsy. Report of four cases. Arch. Ophthal., 78:730, 1967.
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15) Jeavons, P. M. and Harding, G. F. A,:The television epilepsy. Lancet, 2, (7679):926, 1970.

16) 高橋剛夫:図形により誘発されるてんかん. 臨床脳波, 12:380, 1970.

17) Poskanzer, D. C., Brown, A. E. and Miller, H,:Musicogenic epilepsy caused only by a discrete frequency band of church bells. Brain, 85:77, 1962.
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18) Bickford, R. G., Whelan, J. L., Klass, D. W. and Corbin, K. B,:Reading epilepsy;clinical and electroencephalographic studies of a new syndrome. Trans. Amer. Neurol. Ass., 81:100, 1956.

19) Geschwind, N. and Sherwin, I,:Language-induced epilepsy. Arch. Neurol., 16:25, 1967.
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20) 柴崎浩, 安藤祇彦, 加藤元博, 梅崎博敏, 荒木淑郎:不意の頭部触覚刺激によって誘発される驚愕てんかんの1例. 臨床神経学, 9:438, 1969.

21) 加藤元博, 古賀誠, 荒木淑郎, 黒岩義五郎:運動開始によって誘発される発作について, Kinesigenic Seizureの6例. 臨床神経学, 10:299, 1970.

22) Schanzer, S., April, R. and Atkin, A,:Seizures induced by eye deviation. Arch. Neurol., 13:621, 1965.

23) Orban, L. and Lang, J,:Zur Pathogenese der vestibulogenen Epilepsie. Psychiat. Neurol., 146:193, 1963.

24) 大沼悌一, 福島裕, 武田忠厚, 大沢武志, 佐藤時治郎:入浴てんかんの1例. 臨床神経学, 12:386, 1972.

25) Ingvar, D. H. and Nyman, G. E:Epilepsia arithmetices. A new Psychologic trigger mechanism in a case of epilepsy. Neurology, 12:282, 1962.

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P.48 掲載の参考文献

1) Lennox, W. G,:Epilepsy and Related Disorders Vol. 1. Little, Brown & Co., Boston, 1960.

2) Kurtzke, J. F,:Mortality and morbidity data on epilepsy. In Alter, M., Hauser, W. A. (eds):The Epidemiology of Epilepsy. U. S. Dept of Health, Education & Welfare, Washington, D. C., 1972.

3) Kurtzke, J. F., Kurland, L. T., Goldberg, I. D., Choi, N. W. & Reeder, F. A,:Convulsive disorders. In Kurland, L. T., Kurtzke, J. F. & Goldberg, I. D. (eds):Epidemiology of Neurologic and Sense Organ Disorders. Harvard Univ. Press. Cambridge, Mass., 1971.

4) Hauser, W. A. & Kurland, L. T,:The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1976. Epilepsia 16:1, 1975.

5) Rose, S. W., Penry, J. K., Markush, R. E., Radloff, L. A. & Putnam, P. L,:Prevalence of epilepsy in children. Epilepsia 14:133, 1973.
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6) Purpura, D. P,:Relationship of seizure susceptibility to morphologic and physiologic properties of normal and abnormal immature cortex. In Kellaway, P. & Petersen, I. (eds):Neurological and Electroencephalographic Correlative Study in Infancy. Grune & Stratton, New York, 1964.

7) 福山幸夫:小児てんかん. 現代精神医学大系第11巻A, 中山書店, 東京, 1970.

8) Gastaut, H., Gastaut, J. L., Goncalves & Silva, G. E., & Fernandez Sanchez, G. R,:Relative frequency of different types of epilepsy; a study employing the classification of the international league against epilepsy. Epilepsia 16:457, 1975.

9) 福山幸夫:てんかんの診断と治療. 日本小児科学会雑誌72:1462, 1968.

10) Kruse, R,:Epilepsien des Kindesalters. In Matthes, A. & Kruse, R. (herausg):Neuropaediatrie. G. Thieme Verlag, Stuttgart, 1973.

11) Massa, T. & Niedermeyer, E,:Convulsive disorders during the first three months of life. Epilepsia 9:1, 1968.
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12) Schulte, F. J. & Herrmann, B,:Elektroencephalographie beim Neugeborenen, Zuordnung zu anatomischen Befunden und prognostische Bedeutung. Mschr. Kinderh., 113:457-465, 1965.

13) Rodin, E. and Gonzalez, S,:Hereditary components in epileptic patients. J. A. M. A., 198:221-225, 1966.
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14) Eisner, V., Pauli, L L. and Livingston, S,:Hereditary aspects of epilepsy, Bull. Johns Hopkins Hospital, 105:245-271, 1959.

15) Matthes, A,:Epilepsie Fibel. G. Thieme Verlag, Stuttgart, 1969.

16) Aicardi, J,:Benign epilepsy of childhood with Rolandic spikes (BECRS), Brain Develop 1:71-74, 1979.

17) 福山幸夫:小児てんかんの治療法の再検討と新開発の試み. 脳と発達, 10:94-116, 1978.

P.61 掲載の参考文献

1) Berlin, L,:Significance of grand mal seizures developing in patients over thirty-five years of age, J.A.M.A. June, 152(9):794-797, 1953.

2) Celesia, G.G., Messert, B. and Murphy, M,:Status epilepticus of late adult onset. Neurology, 22:1047-1055, 1972.

3) Gastaut, H., Gastaut, J. L., Goncalves e Silva, G.E., and Fernandez Sanchez, G.R,:Relative frequency of different types of epilepsy:A study employing the classification of the international league against epilepsy. Epilepsia, 16:457-461, 1975.
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4) 後藤蓉子:てんかんの経過と予後に関する臨床的研究, 精神経誌, 61:1649-1664, 1959.

5) Gowers, W.R,:Epilepsy and other chronic convulsive diseases:their causes, symptoms & treatment. William Wood and Company, 1885.

6) 橋爪敬三, 高橋宏, 平川公義:外傷性てんかんの発生率とその予後. 災害医学, 17:313-320, 1974.

7) Hauser, W. A. and Kurland, LT,:The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia, 16:1-66, 1975.
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8) Hyllested, K. and Pakkenberg, H,:Prognosis in epilepsy of late onset. Neurology, 13:641-644, 1963.
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34) Cree, J.E., Mayer, J., Hailey, D.M,:Diazepam in labour:Its metabolism and effect on the clinical condition and thermo genesis of thenewborn. Br. Med, J. 4:251, 1973.

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4) 山村均, 中西雅夫:追跡調査からみた熱性痙攣とてんかん. 臨床脳波, 18:133-143, 1976.

5) 中西雅夫, 山村均, 吉水俊一:入眠時高振幅突発性徐波群について. -ひきつけ児の継時的脳波検査より-. 臨床脳波, 18:666-676, 1976.

6) Yamamura, H,:A Follow-up Study of Febrile Convulsions in Relation to Epilepsies. Folia Psychiat. Neurol. Japonica., 30:219-239, 1976.

7) 山村均:熱性けいれんとてんかんの関係. -追跡調査による検索-. てんかん研究の進歩I. 福山編, 東京医学社, 東京. 3-22, 1977.

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9) 吉水俊一:ひきつけ児の脳波的研究. -てんかんの追跡研究を目的として-. 名市大医誌, 23:1-20, 1972.

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11) 坪井孝幸, 遠藤俊一:熱性けいれんから無熱性けいれんへの移行例. 精神医学, 19:19-32, 1977.

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24) Gregoriades, A. D,:A medical and social survey of 231 children with seizures. Epilepsia, 13:13-20, 1972.
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28) Aicardi, J., Chevrie, J.J,:The significance of EEG paroxysms in children less than 3 years of age. Epilepsia, 14:47-55, 1973.
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29) 梶谷喬:小児の大発作てんかんの予後. 臨床脳波, 19:92-100, 1977.

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1) From the Commission on Classification and Terminolagy of the International League Against Epilepsy:Proposal for Revised Clinical and Electroencephalographic Classification of Epileptic Seizures. Epilepsia, 22:489-501, 1981.
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4) 大田原俊輔, 岡英次:痙攣重積状態 prolonged seizure activity. 小児診療, 37:672-680, 1974.

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9) Gastaut, H., Poirier, F., Payan, H., Salamon, G., Toga, M. and Vigouroux, M,:H.H.E. syndrome, Hemiconvulsion, hemiplegia, epilepsy. Epilepsia, 1:418-447, 1960.

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14) Prensky, A.L., Roff, M.C., Moore, M.J. and Schwab, R.S,:Intravenous diazepam in the treatment of prolonged seizure activity. New Eng. J. Med., 276:779-784, 1967.

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5. 抗てんかん薬の臨床

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1) Eadie, M.J. and Tyrer, J.H,:Anticonvulsant therapy, Pharmacological basis and practice. Churchill Livingstone, Edinburgh & London. 1974. 抗てんかん薬の血中濃度. -新しい治療理論 (清野昌一, 宮本侃治訳), 東京医学社, 1978.

2) Guelen, P.J.M. and van der Kleijin, E,:Rational anti-epileptic drug therapy. Elsevier/North-Holland, Amsterdam, 1978.

3) Higashi, T. et al,:Medico-social aspects of people with epilepsy in Japan. 11th Epilepsy International Symposium, Florence, Abstract, 1979.

4) 掛川紀夫, 他:Sodium valproateの血巾濃度の臨床的意義:臨床精神医学, 7:321-328, 1978.

5) Miyamoto, K., Seino, M., Ikeda, Y,:Consecutive determination of the twelve antiepileptic drugs in blood and cerebrospinal fluid:In Clinical pharmacology of antieileptic drugs. ed. Schneider, H. et al., Springer, Heidelberg, 331-336, 1975.

6) 宮本侃治, 清野昌一, 池田佳子:抗てんかん薬の意味ある測定値とその精度:臨床精神医学, 7:301-308, 1978.

7) 宮越雅子, 掛川紀夫, 鷺坂昌史, 清野昌一:Sodium valproateの血中濃度:脳と発達, 11:567-576, 1979.

8) Rodin, E,:The prognosis of patients with epilepsy:Charles. C Thomas, Springfield, 1968.

9) 清野昌一, 宮本侃治:てんかんの薬物療法. -血中濃度を用いた臨床経験:臨床神経学. 17:805-810, 1977.

10) 清野昌一, 宮本侃治:精神科治療における血中濃度測定の意義-. 抗てんかん薬の治療有効濃度:精神医学, 20:489-493, 1978.

11) 清野昌一:抗てんかん薬血中濃度測定の治療的意義:臨床精神医学, 7:269-281, 1978.

12) Simonsen, N., Zander Olsen, P., Kuhl, V.., Lund, M. and Wendelboe, J,:A comparative controlled study between carbamazepine and diphenylhydantoin in psychomotor epilepsy:Epilepsia, 17:169-176, 1976.

13) 和田豊治:臨床てんかん学, 金原書店, 東京. 1973.

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2) Cluff, L.E., Thornton, G. and Seidl, L,:Epidemiological study of adverse drug reactions. Trans Assoc Amer Physicians, 78:255-268, 1965.

3) Ward, A.A,:Official names of antiepileptic drugs. Epilepsia, 19:430, 1978.

4) Booker, H.E,:Idiosyncratic reactions to the antiepileptic drugs. Epilepsia, 16:171-181, 1975.

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10) Beutler, E,:Glucose-6-phosphate dehydrogenase deficiency. In:J.B, Stansbury, J.B, Wyngarrden, and D.S, Frederickson, (Eds.), The Metabolic Basis of Inherited Disease, 3rd ed. McGraw-Hill, New York, 1972, pp.1358-1388.

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20) Buchthal, F., Svensmark, O. and Simonsen, H,:Relation of EEG and seizures to phenobarbital in serum. Arch. Neurol (Chic), 19:567-572, 1968.

21) Penry, J.K,:Correlation of serum ethosuximide levels with clinical effect. In:H. Schneider, D. Jandz, C. Gardner-Thrope, et al.(Eds.), Clinical Pharmacology of Anti-Epileptic Drugs. Sprillger Verlarg Berlin Heidelberg N.Y., 1975, pp.217-220.

22) 掛川紀夫, 宮越雅子, 鷺坂昌史, 清野昌一, 和田豊治:Sodium valproate の血中濃度の臨床的意義. 臨床精神医学, 7:321-328, 1978.

23) 武田明夫, 後藤浩, 天野嘉之, 久木野和曉:新しい抗てんかん剤Sodium valproateの血中及び髄液中濃度に関する臨床的研究. 脳と発達, 8:401-408, 1976.

24) 清野昌一:抗てんかん薬血中濃度測定の治療的意義. 臨床精神医学, 7:269-281, 1978.

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29) Richens, A,:Clinical Pharmacology and Medical Treatrnent. In:Laidlaw, J., and Richens, A. (Eds.), A Textbook of Epilepsy. Churchill Livingstone, pp.185-247, 1976.

30) 武田明夫:抗てんかん剤による骨代謝異常に関する研究. 名古屋医学, 100:1-7, 1977.

6. てんかんの社会的問題点

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1) Freeman, J. and Gayle, E,:Rehabilitation and the client with epilepsy; A survey of the client's view of the rehabilitation process and its results. Epilepsia, 19:233-239, 1978.

2) 福島裕, 三川博, 工藤信夫, 山鼻康弘:てんかんの社会精神医学的研究. -てんかん者の結婚について-. 臨床精神医学, 5:101-107, 1976.

3) Laidlaw, J. and Richens, A,:A Textbook of Epilepsy. Churchill-Livingstone, Edinburgh, 1976,

4) 直居卓, 渡辺敏也, 熊本亮:社会的背景. 現代精神医学大系 (てんかんII). 中山書店, 東京, 135-163, 1977.

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6) Risch, F,:Requisites for rehabilitation;Evaluation・training・changing employers' attitudes・creative rehabilitation planning. Modern perspectives in epilepsy (Ed. Juhn, A. Wada). Eden Press Inc., 151-156, 1978.

7) Rodin, E,:The Prognosis of Patients with Epilepsy. C. Thomas, Springfield, 1968.

8) Van der Lugt, PJM,:Traffic accidents caused by epilepsy. Epilepsia, 16:747-751, 1975.

9) 山鼻康弘:てんかんの社会精神医学的研究. 第1部:外来通院患者の社会適応・環境面を中心として. 精神経誌, 71:48-62, 1969.

10) 山鼻康弘, 工藤信夫:てんかんの社会精神医学的側面. -交通問題を中心に-. 臨床精神医学, 1:104-115, 1972.

11) 和田豊治, 山鼻康弘:てんかんの社会医療-そのいとぐち-. 社会精神医学, 1:150-158, 1978.

12) 和田豊治:てんかん者の自動車運転免許の問題. -国際てんかんシンポジウム (1965) から-. 精神医学, 9:429-437, 1967.

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7. てんかんの予後

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6) Blakemore, C. B. & Falconer, M. A,:Long term effects of anterior lobectomy on certain cognitive functions, J. Neurol. Neurosurg., 30:364-367, 1967.

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