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総論

P.14 掲載の参考文献

• 1) The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus:Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 20:1183-1197, 1997.
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• 2) Alberti KGMM, Zimmet PZ for the WHO Consultation:Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:Diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation. Diab Med 15:539-553, 1998.

• 3) 葛谷健ほか:糖尿病の分類と診断基準に関する委員会報告. 糖尿病 42:385-404, 1999.

P.19 掲載の参考文献

• 1) 糖尿病性腎症に関する合同委員会:糖尿病性腎症病期分類厚生省案の改定について. 糖尿病44:623, 2001.

• 2) Lewis EJ, Hunsicker LG, Bain RP, et al.:The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. New Engl J Med 329:1456-1462, 1993.
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• 3) Parving H-H, Lehnert H, Brochner-Mortensen J, et al.:The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. New Engl J Med 345:870-878, 2001.
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• 4) Lewis EJ, Hunsicker LG, Clarke WR, et al.:Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. New Engl J Med 345:851-860, 2001.
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• 5) Brenner BM, Cooper ME, de Zeeuw D, et al.:Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. New Engl J Med 345:861-869, 2001.
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• 6) 糖尿病性神経障害を考える会:糖尿病性多発神経障害 (distal symmetrical polyneuropathy) の簡易診断基準. 末梢神経12:225-227, 2001.

• 7) Gaede P, Vedel P, Larsen N, et al.:Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. New Engl J Med 348:383-93, 2003.
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P.23 掲載の参考文献

• 1) Eriksson KF, et al.:Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise;the 6-year Malmo feasibility study. Diabetologia 34:891, 1991
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• 2) Pan XR et al.:Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance;Da Qing IGT and Diabetes study. Diabetes Care 20:537, 1997

• 3) Tuomilehto J et al:Prevention of type 2 diabetes mellitus by changes in life style among subjects with impaired glucose tolerance. N Engl J Med 344:1343, 2001
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• 4) DPP research group:Reduction in incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393, 2002
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• 5) Eriksson KF et al.:No excess 12-year mortality in men with impaired glucose tolerance who penicipated in the Malmo preventive trial with diet and exercise. Diabetologia 41:1010, 1998
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• 6) Anderson JW et al.:Metabolic effects of high carbohydrate, high fiber diets for insulin dependent diabetic indivisuals. Am J Clin Nutr 54:936, 1991

• 7) Garg A et al.:Comparison of effects of high and low carbohydrate diet on plasma lipoproteins and insulin sensitivity in patients with mild diabetes. Diabetes 41:1278, 1992
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• 8) Smaha FF et al.:A low-carbohydrate as compared With a low-fat diet in severe obesity. N Engl J Med 348:2074, 2003

• 9) Foster GD et al.:A randomized trial of low-carbohydrate diet for obesity. N Engl J Med 348:2082, 2003
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P.31 掲載の参考文献

• 1) 葛谷 健他:糖尿病の分類と診断に関する日本糖尿病学会委員会報告. 糖尿病 42:385, 1999.

• 2) 日本糖尿病学会編「糖尿病遺伝子診断ガイド」第2版2003. 文光堂

• 3) Shimomura S. et al:Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patients with a strong family history. Diabetes 49:1597, 2000.

• 4) Shimajiri Y. et al.:A missense mutation of Pax4 gene (R121W) is associated with type 2 diabetes in Japanese. Diabetes 50:2864, 2001.
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• 5) Waeber G. et al.:The gene MAPK81P1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nat Genet. 24:291, 2000.
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• 6) Nishigori H. et al.:Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci USA. 98:575, 2001
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• 7) Njolstad PR et al.:Neonatal diabetes mellitus due to complete glucokinase deficiency. New Engl J Med 344:588, 2001

• 8) Sakagashira S et al.:Missense mutation of amylin gene (S20G) in Japanese NIDDM patients. Diabetes 45:1279, 1996.
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• 9) Seino S. et al.:S20G mutation of the amylin gene is associated with type II diabetes in Japanese. Diabetologia 44:906, 2001.
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• 10) Inoue H et al:A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) . Nat Genet 20:143, 1998.
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• 11) Labay V. et al.:Mutation in SLC19A2 cause thiamine-responsive megaloblastic anemia associated with diabetes mellitus and deafness. Nature Genet 22:300, 1999.
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• 12) Delepine M et al.:EIF2AK3, encoding translation initiation factor 2-a kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 25:406, 2000.
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• 13) Bennett CL et al.:The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutation of FOXP3. Nat Genet 27:20, 2001.
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• 14) Nagamine K et al.:Positional cloning of APECED gene Nat Genet 17:393, 1997.
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• 15) Katsanis N, Ansley SJ, Badano JL et al.:Trialleic Inheritance in Bardet-Biedl Syndrome, a Mendelian Recessive Disorder. Science 293:2256, 2001.

• 16) Savkur RS, et al.:Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nature Genet 29:40, 2001.
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• 17) Cao H et al:Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodys-trophy. Hum. Molec Genet 9:109, 2000
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• 18) Agarwal AK et al.:A novel heterozygous mutation in peroxisome proliferators-activated receptor-γgene in a patients with familial partial lipodystrophy. J Clin Endocrinol Metab 87:408, 2002.

• 19) Magre J et al.:Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat Genet 28:365, 2001.
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• 20) Agarwal AK, Arioglu E, de Almeida S, et al.:AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome gq34. Nature Genet 31:21-23, 2002.
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疾患編

P.47 掲載の参考文献

• 1) 葛谷 健, 中川昌一, 佐藤 譲, ほか:糖尿病の分類と診断基準に関する委員会報告. 糖尿病42:385-404, 1999.

• 2) DECODE Study Group, the European Diabetes Epidemiology Group:Glucose tolerance and cardiovascular mortality:comparison of fasting and 2-hour diagnostic criteria. Arch lntern Med 161:397-405, 2001.

• 3) 葛谷 健:医療機関受診中の糖尿病患者における合併症の実態調査. 「平成3年度糖尿病調査研究報告書」, p. 33-38, 厚生省, 1992.

• 4) Ohkubo K, Kishikawa H, Araki E, et al:Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus:a randomized prospective 6-year study. Diabetes Res Clin Pract 28:103-117, 1995.

• 5) UK Prospective Diabetes Study (UKPDS) Group:Intensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes:UKPDS 33. Lancet 352:837-853, 1998.

• 6) Stratton IM, Adler AI, Neil HA, et al:Association of glycaemia with macrovascular and microvascular complications of type 2 dia-betes (UKPDS 35):prospective observational study. Br Med J 321:405412, 2000.

• 7) UK Prospective Diabetes Study Group:Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes:UKPDS 38. Br Med J 317:703-713, 1998.

• 8) Pyorala K, Pedersen TR, Kjekshus J, et al:Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S) . Diabetes Care 20:614-20, 1997.
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P.53 掲載の参考文献

• 1) 朝川秀樹, 徳永勝人:内臓脂肪型肥満と内臓脂肪症候群. 日本臨牀 61 (増刊号 6 肥満症):433, 2003.

• 2) 日本肥満学会診断基準検討委員会:委員会報告, 新しい肥満の判定と肥満の診断基準. 肥満研究 6:18-28, 2000.

• 3) 藤岡滋典ほか:体脂肪の判定法. 日本臨牀 61 (増刊号 6 肥満症), 357-362, 2003

• 4) 船橋徹, 前田和久:アディポサイトカイン 概論. 日本臨牀 61 (増刊号 6 肥満症):314-319, 2003

P.63 掲載の参考文献

• 1) 古庄敏行ほか:インスリン依存型糖尿病の遺伝的異質性に関する研究 (I)-発症年齢分布を複合正規分布と仮定した統計遺伝学的解析-. 糖尿病 27 (9):981-992, 1984

• 2) 森 豊ほか:高齢で急性発症したインスリン依存型糖尿病の1剖検例. 糖尿病 35 (6):487-493, 1992

• 3) 小林哲郎:slowly progressive IDDM. 小坂樹穂編 糖尿病学1983. pp 205-224, 診断と治療社, 1983

• 4) 藤田基寛ほか:14年間の2型糖尿病の経過後に膵島関連自己抗体が陽性化し, 進行性インスリン分泌低下を認めた高齢糖尿病の1例. 糖尿病43 (9):803-808, 2001

• 5) 田中 剛史ほか:重篤な糖尿病網膜症を合併した高齢発症1型糖尿病の1例. 糖尿病46 (2):135-138, 2003

• 6) 赤井 真弓ほか:糖尿病性ケトアシドーシスで発症し, 横紋筋融解症と各種膵酵素の上昇を示した成人発症IDDMの1例. 奈良医誌 46 (6):606-609, 1995

• 7) 岩谷 逸平ほか:C型慢性肝炎に対するインターフェロン治療後にIDDMに移行したNIDDMの1例. 糖尿病 38 (6):455-460, 1995

• 8) 森田 弘之ほか:悪性貧血で発症し, 慢性甲状腺炎を合併した高齢発症1型 (緩徐進行型) 糖尿病の1例. 糖尿病 44 (10):831-836, 2001

P.68 掲載の参考文献

• 1) The Diabetes Control and Complication Trial Research Group:The effect of intensive treatment of diabetes on the development and progressive of longterm complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986, 1993

• 2) Ohkubo Y, et al:Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanease patients with non-insulin-dependent diabetes mellitus a randomized prospective 6-year study. Dibetes Res Clin Pract 28:103-117, 1995

• 3) 酒井 謙, 小沼 富男, 河盛 隆造:超速効型インスリンの特徴と治療のポイント:インスリンリスプロ. プラクティス 19:150-152, 2002
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• 4) 松田 昌文, 加来 浩平:超速効型インスリンの特徴と治療のポイント:インスリンアスパルト.プラクティス 19:153-157, 2002
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• 5) Kaku K, et al.:Pharmacokinetics and pharmacodynamics of insulin aspart, a rapid-acting analog of human insulin, in healthy Japanese volunteers. Diabetes Res. Cli Pract 49:119-126, 2000.

• 6) Anderson JHJr, et al.:Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patient on insulin-analog treatment. Diabetes 46:265-270, 1997

• 7) Raskin P, et al.:Use of insulin aspart, a fasting insulin analog, as the mealtime insulin in the management of patients with type l diabetes. Diabetes Care 20:1287-1289, 2000

• 8) Anderson, J. HJr. et al.:Mealtime treatment with insulin analog improves postprandial hyperglycemia and hypoglycemia in patients with insulin-dependent or non-insulin-dependent diabetes mellitus. Multicenter insulin lispro study group. Arch Inter Med 157:1249-1255, 1997.

• 9) Zinman B, et al:Insulin lispro in CSII:Results of double-blind crossover study. Diabetes 45:440-443, 1997

• 10) 加来 浩平:インスリン治療実践マニュアル. 28-29, 南江堂, 2003

P.81 掲載の参考文献

• 1) 佐中真由実, 柳沢慶香, 岩本安彦, ほか:糖尿病女性における計画妊娠の重要性. Diabetes Frontier:679-684, 1999
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• 2) 栄養問題委員会報告 (委員長:須川吉):妊娠糖尿病, 糖尿病合併妊娠の管理指針 (案) . 日本産婦人科学会雑誌 37:473-477, 1985

• 3) 佐中真由美:妊娠の栄養・食事指導の実際:糖尿病合併妊娠. 周産期医学 31:227-230, 2001

• 4) Hales CN, Barker DJP, Clark PMS, et al:Fetal and infant growth and impaired glucose tolerance at age 64. BJM 303:1019-1022, 1991

• 5) 和栗雅子:妊娠糖尿病と先天奇形 「妊娠と糖尿病」診療スタンダード. 藤田富雄, 豊田長康編著, 金芳堂, 京都, p 253-259, 2002

• 6) 大森安恵, 佐中真由実, 清水明美:妊娠・分娩・産褥と内科疾患. 井村裕夫, 他編:最新内科学体系 77 糖尿病, 中山書店, 東京, p 189-200, 1994

• 7) Kitzmiller JL, Gavin LA, Gin GD et al:Preconception care of diabetes. Glycemic control prevents congenital anomalies. JAMA 265:731-736, 1991
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P.85 掲載の参考文献

• 1) Service FJ, et al.:Mean amplitude of glycemic excursions, a measure of diabetic instability. Diabetes 19:644-55, 1970.

• 2) Schlichtkrull J, et al.:The M-value:an index of blood sugar control in diabetics. Acta Med. Scand. 177:95-102, 1965.

• 3) Shima K, et al.:Studies on the etiology of "brittle diabetes" relationship between diabetic instability and insulinogenic reserve. Diabetes 76:717-25, 1977.

• 4) 野中共平:Brittle diabetesとその治療. 糖尿病 22:1356, 1979.

• 5) 難波光義, 河野典夫:不安定型糖尿病. 糖尿病-最近の展開 (改訂第2版), p. 123-132, 南江堂, 1994

P.105 掲載の参考文献

• 1) American Diabetes Association;Hyperglycemic crisis in patients with diabetes mellitus, Diabetes Care 25 (S1):108, 2002

• 2) 藤田 淳, ほか:糖尿病性ケトアシドーシスと高血糖性高浸透圧性昏睡の輸液療法. 治療 85 (2), 2003

• 3) 花房俊昭, ほか:劇症1型糖尿病. 内科 91 (1), 2003
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• 4) 長岡 匡, ほか:急性膵炎発症後急速にインスリン依存状態をきたし, 単純ヘルペスウイルスの関与が考えられた糖尿病の1例. 糖尿病 44:315, 2001

• 5) 中條大輔, ほか:非自己免疫性劇症1型糖尿病の臨床像を呈したが抗GAD抗体が陽性であった1例. 糖尿病 46 (2), 2003

• 6) Akihisa lmagawa, et al.:Fulminant type l diabetes;A nationwide survey in Japan. Diabetes Care 26 (8):2345-2352, 2003

P.114 掲載の参考文献

• 1) JC Pickup, G Williams:Textbook of diabetes (3rd ed.), Blackwell Science , 2003.

• 2) 吉利 和:内科診断学, 金芳堂, 1997.

• 3) 日本糖尿病学会:糖尿病治療ガイド, 文光堂, 2002.

P.132 掲載の参考文献

• 1) Thomas PK:Classification of different diagnosis, and staging of diabetic peripheral neuropathy. Diabetes 46:S54-S57, 1997
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• 2) 馬場正之:糖尿病性神経障害. 最新日本内科学大系「糖尿病」, p 340-350, 中山書店, 東京, 1995.

• 3) 馬場正之:糖尿病患者におけるしびれ. プラクティス 18:14-15, 2001.
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• 4) Stewart JD:Diabetic truncal neuropathy:topography of sensory deficit. Ann Neurol 25:233-238, 1989.
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• 5) 馬場正之:神経疾患としての糖尿病性ニューロパチー. プラクティス 18:120-121, 2001.
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• 6) Sivak M, Ochoa J, Femadez JM:Positive manifestations of nerve fiber dysfunction:clinical electrophysiologic and pathologic correlations. In "Clinical Electgromyography 2nd ed. " Brown WF, Bolton CF (eds) m Butterworth-Heinemann, Boston, p 117-147, 1993.

• 7) 馬場正之:神経痛. 最新内科学大系70「末梢・自律神経疾患」, p 211-219, 中山書店, 東京, 1996.

• 8) 糖尿病性神経障害を考える会:糖尿病性多発神経障害の簡易診断基準. 末梢神経11:150, 2000.

• 9) Kohara N, Kimura J, Kaji R Goto Y, Ishii J, Takiguchi M, Nakai M:F-wave latency serves as the most reproducible measure innerve conduction studies of diabetic polyneuropathy:multicentre analysis in healthy subjects and patients With diabetic polyneuropathy. Diabetologia 43:915-921, 2000.

• 10) 馬場正之:神経伝導検査概論. 解剖生理学的基盤と所見解釈の原理. 脳の科学24:71-77, 2002.

• 11) Watahiki Y, Baba M, Matsunaga M, et al:Sympathetic skin response in diabetic neuropathy. Electromyogr Clin Neurophysiol 29:155-9, 1989.
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• 12) 金春玉, 馬場正之, 松永宗雄:健常成人における運動神経伝導パラメータの左右差について. 臨床脳波45:234-238, 2003.

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• 14) Sindrup SH, Jensen TS. Pharmacologic treatment of pain in polyneuropathy. Neurology 55:915-920, 2000.
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P.139 掲載の参考文献

• 1) Zimmet P, Alberti KGMM, Shaw J:Global and societal implications of the diabetes epidemic. Nature 414, 782-787 doi:10. 1038/414782a, 2001

• 2) Reaven GM:Pathophysiology of insulin resistance in human disease. Physiol-Rev, 75, 473-486, 1995
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• 3) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATPIII) . JAMA 285, 2486, 2001

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P.148 掲載の参考文献

• 1) Alberti K GMM, et al.:Definition, Diagnosis and classhication of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553, 1998.

• 2) Kobayashi T, et al.:Time Course of lslet Cell Antibodies and B-cell Function in Non-insulin-dependent Stage of Type l Diabetes. Diabetes 36:510-517, 1987

• 3) Kobayashi T, et al.:Immunogenetic and clinical characterization of slowly Progressive IDDM. Diabetes Care 16:780788, 1993,

• 4) Nakanishi K, et al.:Association of HIA-A24 with complete B-cell destruction in insulin-dependent diabetes mellitus. Diabetes 42:1086-1093, 1993.

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• 8) Kobayashi T, et al.:Histopathological changes of the pancreas in islet cell antibodies (ICA) positive subjects befre and after the clinical onset of insulin-dependent diabetes mellitus (IDDM) . Diabetes 37:24A

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P.152 掲載の参考文献

• 1) 山田研太郎, 高根直子, 野中共平, ほか:ケトーシスを伴って急性発症する肥満NIDDM症例-清涼飲料水ケトーシス-. 糖尿病 36:469-473, 1993

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