書籍詳細

第1章 必須微量栄養素としての亜鉛

P.2 掲載の参考文献

• Bowen HJM:Trace Elements in Biochemistry.Academic Press,London,1966

• Underwood EJ:Trace Elements in Human and Animal Nutrition.Academic Press,New York,London,1971

• Davis IJT:The Clinical Significance of the Essential Biological Metals.William Heinemann Med Book,London,1972

• Underwood EJ,日本化学会訳編:微量元素-栄養と毒性-,丸善,1975

• Bronner F,Coburn JW(ed):Disorders of Mineral Metabolism.Vol 1.Academic Press,New York,1981

• 不破敬一郎編著:生体と重金属,講談社,1981

• Rose J(ed):Trace Elements in Health.A Review of Current Issues.Butterworths,London,1983

• Mills CF,Brenner I,Chester JK(ed):Trace Elements in Man and Animals-TEMA 5,Commonwealth Agricultural Bureaux UK,1985

• 和田攻:金属とヒト-エコトキシコロジーと臨床-,朝倉書店,1985

• Merz W(ed):Trace Elements in Human and Animal Nutrition.Fifth ed.Academic Press,Boston,1986

• 木村修一,左右田健次編:微量元素と生体,秀潤社,1987

• 荒川泰行,竹内重雄編著:微量金属と消化器疾患,新興医学出版,1990

• 糸川嘉則,五島牧郎編:生体内金属元素,光生館,1994

• 桜井弘,田中英彦:生体微量元素,廣川書店,1994

• 千葉百子,鈴木和夫編:健康と元素-その基礎知識-,南山堂,1996

• 桜井弘:元素111 の新知識,講談社,1996

• O'Dell BL,Sunde RA(ed):Handbook of Nutritionally Essential Mineral Elements.Marcel Dekker,New York,1997

• 山口正義編:バイオメタル-生体調節の多彩な役割と病態-,黒船出版,1998

• 糸川嘉則編:ミネラル事典,朝倉書店,2003

• 桜井弘(編):生命元素事典,オーム社,2006

• Prasad AS(ed):Zinc Metabolism.Charles C Thomas,Springfield, Illinois,1966

• Pories WJ,Strain WH(ed):Clinical Application of Zinc Metabolism.Charles C Thomas,Springfield,Illinois,1974

• Prasad AS:Trace Elements in Human Health and Disease.Vol 1,Zinc and Copper.Academic Press,New York,1976

• Karcioglu ZA,Sarper RM(ed):Zinc and Copper in Medicine.Charles C Thomas,Springfield,Illinois,1980

• 岡田正,高木洋治編:亜鉛と臨床,朝倉書店,1984

• Mlls CF(ed):Zinc in Human Biology.Springer-Verlag,London,1988

• 冨田寛:元気になるミネラル・亜鉛パワーの秘密,宙出版,1998

• 有沢祥子:必須ミネラル亜鉛・超健康法,KKベストセラーズ,2001

• 宮田學:亜鉛と健康-不老と長寿の必須微量金属-,丸善,2005

• (特集)金属と生体,代謝,第12巻 第3号,1975

• (特集)肝と金属代謝,肝胆膵,第10巻 第6号,1985

• (特集)微量元素-New Trends 1990-,最新医学,第45巻 第4号,1990

• (特集)微量元素,小児医学,第25巻 第2号,1992

• (特集)必須微量元素の臨床,日本臨床,第54巻 第1号,1996

• (特集)微量元素と生体調節-病態修復へのアプローチ-,Biomed Res Trace Elements Vol 13 No2,2002

• (特集)微量元素の臨床-実地医家の理解と実践のために-,日本医師会雑誌,第129巻 第5号,2003

• (特集)日常診療で知っておきたい微量元素の知識,治療,第88巻 第7号,南山堂,2006

• (特集)生体微量金属-恒常性維持・疾患との関係を紐解く-細胞工学,Vol 27 No3,2008

• (特集)生体内微量元素,臨床検査,Vol 53 No2,2009

• (特集)亜鉛の臨床,消化器の臨床,第2巻 第1号,1999

• (特集)Zinc and Health:Current Status and Future Directions.J Nutrition,Vol 130 No 5S,2000

• (特集)亜鉛の有用性を探る-臨床での亜鉛補充による効果とその考え方-,治療別冊,第87巻,臨時増刊,南山堂,2005

• (特集)亜鉛と高齢者疾患,老年消化器病,第19巻 第2号,2007

P.5 掲載の参考文献

• 蟹沢成好:必須微量元素の現況,代謝 12:237,1975

• Yukawa M et al:Distribution of trace elements in the human body determined by neutron activation analysis.Arch Environ Health 35:36,1980
  pubmed

• Merz W:The essential trace elements.Science 213:1332,1981

• 玄番昭夫:生体内微量元素とその分析,医学のあゆみ 120:369,1981

• 和田攻ほか:微量金属代謝とその異常,日本臨床 39:1949,1981
  Medical*Online

• 和田攻:微量元素と臨床,医学のあゆみ 137:1063,1986
  Medical*Online

• 不破敬一郎:生体と微量元素-過去,現在,未来-,Biomed Res Trace Elements 1:7,1990

• 木村修一:微量元素の必須性,最新医学 45:808,1990
  Medical*Online

• 丸茂文昭:微量元素の代謝異常,日本内科学会誌 80:195,1991

• 松田一郎:微量元素と栄養学,小児医学 25:203,1992

• Shenkin A:Trace elements and inflammatory response:Implication for nutritional support. Ntrition 11:100,1995
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• 和田攻,柳沢裕之:微量元素の種類とその生理的役割,日本臨床 54:5,1996
  Medical*Online

• 和田攻:微量元素とは-その欠乏症と過剰症-,日本医師会雑誌 129:607,2003

• 柳澤裕之:生命と微量元素-なぜ生体に微量元素は必要か-,治療 88:1839,2006

• 荒川泰昭,小川康恭,荒記俊一:微量元素の代謝と生理的機能,臨床検査 53:149,2009

P.7 掲載の参考文献

• Gunn SA:Zinc protection against cadmium injury to rat testis.Arch Path 71:274,1961
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• Smith SM,Levvy GA:α-Mannosidase as a zinc-dependent enzyme.Nature 218:91,1968

• Ganther HE et al:Selenium:Relation to decreased toxicity of methylmercury added to diets containing tuna.Science 175:1122,1972
  pubmed

• Lee IP,Dixon RL:Effects of cadmium on spermatogenesis studied by velocity sedimentation cell separation and serial mating.J Pharmacol Exp Ther 187:641,1973
  pubmed

• 和田攻:金属の生体内拮抗・相互作用,代謝 12:219,1975

• 山根靖弘:水銀中毒に対するセレンの抑制作用とその機序に関する研究,微量金属代謝 5:1,1978

• 山崎素直:微量金属の生体内作用,代謝 20:595,1983

• 坂井和男,山根靖弘:金属と核酸,代謝 20:605,1983

• Oestreicher P,Cousins RJ:Copper and zinc absorption in the rat.:Mechanism of mutual antagonism.J Nutr 115:159,1985
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P.9 掲載の参考文献

• Smith JC et al:Zinc:A trace element in vitamin A metabolism.Science 181:954,1973
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• Abdulla M:Vitamin A deficiency,xerophtalmus and blindness,Nutr Review 32:350,1974

• Krasner N et al:Ascorbic acid saturation and ethanol metabolism.Lancet 2:693,1974
  pubmed

• Smith JC et al:Plasma vitamin and zinc concentrations in patients with alcoholic cirrhosis.Lancet 31:1251,1975

• Miyata S,Inada M:Effects of divalent cations on vitamin B12 adsorption to brush borders of rat intestine.J Nutr Sci Vitaminol 22:187,1976
  pubmed

• Leach RM:Metabolism and function of manganese.In Trace Elements in Human Health and Disease.Vol 2(Prasad AS & Oberleas D ed),Academic Press,London,1976,p235

• Morrison SA et al:Zinc deficiency.A cause of abnormal dark adaptation in cirrhosis.Am J Clin Nutr 31:276,1976

• Yunice AA et al:Effect of ascorbic acid and zinc sulfate on ethanol toxicity and metabolism.Proc Soc Exp Biol Med 154:146,1977
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• Hegstead DM:Liver vitaminA mobilization during zinc deficiency and restricted food intake. Nutr Rev 35:213,1977

• Keltz FR et al:Urinary ascorbic acid excretion in the human as affected by dietary fiber and zinc.Am J Clin Nutr 31:1167,1978
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• Palin D et al:The effect of oral zinc supplementation on plasma level of vitamin A and retinol binding protein in cystic fibrosis.Am J Clin Nutr 32:1253,1979
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• Shingwekar AG et al:Effects of zinc supplementation on plasma levels of vitamin A and retinol binding protein in malnourished children.Clin Chim Acta 93:97,1979
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• Morley JE et al:The relationship of thyroid hormones with vitamin A and zinc nutritional status in patients with chronic hepatic and gastrointestinal disorders.Am J Clin Nutr 34:1489,1981
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• Dickerson JWT:Vitamins and trace elements in the seriously ill patients. Acta Chir Scand(suppl) 507:144,1981

• Levander OA:Clinical consequences of low selenium intake and its relationship to vitamin E.Ann N.Y.Acad Sci 393:70,1982
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• Scholmerich J et al:Zinc and vitamin A deficiency in liver cirrhosis. Hepato-gastroenterol 30:119,1983

• 紀氏汎恵:ビタミンとの関係,岡田正,高木洋治編:亜鉛と臨床,朝倉書店,1984,p44

• 竹内重雄:ビタミンと微量元素-とくにアスコルビン酸欠乏と微量金属-,最新医学 45:776,1990

• 宮田學:微量金属とビタミン,内野治人監修:図説臨床ビタミン学,科学評論社,1994,p316

• 和田攻,石川晋介,真鍋重夫ほか:必須金属と欠乏症,臨床医 8:1517,1982

• 松田一郎:微量元素の栄養学.小児医学 25:203,1992

• 田中久:必須微量元素としての亜鉛の有用性と安全性,薬局 98:1297,1997

• 正田良介,松枝啓:経腸栄養と微量元素欠乏症,JJPEN 20:255,1998

• 和田攻ほか:エビデンスに基づいた微量元素欠乏症の臨床,日本医師会雑誌 129:589,2003

• 後藤政幸:微量元素欠乏症・過剰症,臨床検査 53:181,2009

P.11 掲載の参考文献

• Colemann DH et al:The treatment of iron deficiency anemia.Blood 10:567,1955

• Richter GW:The nature of storage iron in idiopathic hemochromatosis and in hemosiderosis:Electron optical chemical and serological studies on isolated hemosiderin granules.J Exp Med 112:551,1960
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• 高久史麿:ヘモクロマトーシス,代謝 14:1575,1977

• 内田俊和:金属中毒と肝病変,肝胆膵 10:931,1985

• 荒川泰行ほか:肝疾患と微量元素,治療 88:1907,2006
  Medical*Online

• 植田亮ほか:細胞の鉄代謝調節機構 ミトコンドリアの新たな機能,細胞工学 27:214,2008

• 川端浩:個体レベルでの鉄代謝調節機構,細胞工学 27:219,2008

• 林久男ほか:慢性疾患における鉄毒性,細胞工学 27:242,2008

P.13 掲載の参考文献

• Cordano A et al:Copper deficiency in infancy.Pediatrics 34:324,1964
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• Chuttani HK et al:Acute copper sulfate poisoning.Am J Med 39:849,1965
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• Lindquist RR:Studies on the pathogenesis of hepatolenticular degeneration.II.Cytochemical methods for the localization of copper.Arch Path 87:370,1969
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• Karpel JT et al:Copper deficiency in long-term parenteral nutrition.J Pediatr 80:32,1972
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• Ashkenazi A et al:The syndrome of neonatal copper deficiency.Pediatrics 52:525,1973
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• 鈴江純史ほか:銅欠乏症の4症例-臨床像と治療に関する考察-, 日本小児科学会誌 86:1228,1982

• Danks DM:Copper deficiency in humans. Annu Rev Nutr 8:235,1988
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• 有馬正高:微量元素と遺伝疾患-特にWilson病およびMenkes病について-,最新医学 45:697,1990

• 青木継稔ほか:Wilson病と微量元素-とくに銅代謝-,小児医学 25:315,1992

• 児玉浩子:Menkes病とCu代謝,小児医学 25:335,1992

• 小椋康光,鈴木和夫:銅の細胞内輸送と制御機構,Biomed Res Trace Elements 13:3,2002
  Medical*Online

• 青木継稔:銅欠乏症とその臨床の実際,日本医師会雑誌 129:617,2003

• Caruano-Yzermans AL et al:Mechanism of the copperdependent turnover of the copper Chaperone for superoxide dismutase.J Biol Chem 281:13581,2006
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• 小椋康光,鈴木和夫:メタロミクスと銅シャペロン,治療 88:1847,2006
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• 遠藤文夫,中村公俊,三渕浩:遺伝性神経疾患と微量元素,治療 88:1957,2006

• 青木継稔:Wilson病の病態生理と臨床,医学のあゆみ 216:808,2006
  Medical*Online

• 清水教一ほか:本邦におけるWilson病に対する酢酸亜鉛製剤(NPC-02)の有効性と安全性に関する検討,日本先天代謝異常学会雑誌 24:71,2008

• 青木継稔,清水教一,山口之利,中村浩章,渡辺温子:Wilson病の新しい治療法-亜鉛薬の使い方-,小児科 49:827,2008

• 斉藤昇:銅代謝と加齢,Biomed Res Trace Elements 20:3,2009

P.14 掲載の参考文献

• Rotruck JT et al:Selenium;Biochemical role as a component of glutathione peroxidase.Science 179:588,1973
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• Van Rij AM et al:Selenium deficiency in total parenteral nutrition.Am J Clin Nutr 32:2076,1979
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• Keshan Disease Research Group of the Chinese Academy of Medical Sciences,Beijing,Antiepidemic Station of Sichuan Province,Chengdu,antiepidemic Station of Xichang District,Sichuan and Antiepidemic Station Mianning Country,Sichuan:Observation on effect of sodium selenite in prevention of Keshan disease.Chinese Med J 92:471,1979

• Chen X et al:Studies on the relations of selenium and Keshan disease.Biol Trace Element Res 2:91,1980

• Wilber CG:Toxicology of selenium;A review.Clin Toxicol 17:171,1980
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• Yang G et al:Selenium-related endemic diseases and the dietary selenium requirement of humans.World Rev Nutr Diet 55:98,1988
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• 山東勤弥,岡田正:セレンと脂肪代謝,小児医学 25:369,1992

• Beck MA et al:Rapid genomic evalution of a non-virulent coxackie virus B3 in selenium-deficient mice results in selection of identical virulent isolates.Nature Med 5:433,1995

• Tsuda K,Yokoyama Y,Morita M et al:Selenium and chromium deficiency during long-term home total parenteral nutrition in chronic idiopathic intestinal pseudo-obstruction.Nutrition 14:291,1998

• 姫野誠一郎:セレン欠乏症,日本医師会雑誌 129:655,2003

• 小山洋ほか:セレン補充による化学がん予防と老化,Biomed Res Trace Elements 20:19,2009
  Medical*Online

P.16 掲載の参考文献

• Miyata S,Nakamura S,et al:Determination of manganese in tissues by neutron actination analysis using antimony pentoxide column.Clin Chim Acta 106:235,1980

• 宮田学,中村重信ほか:筋萎縮性側策硬化症(ALS)における脊髄内マンガン分布について-放射化分析法による微小組織中Mn 定量-,臨床神経学 20:917,1980

• Miyata S,Nakamura S,et al:Increased manganese level in spinal cords of amyotrophic lateral sclerosis determined by radiochemical neutron activationanalysis.J Neurol Sci 61:283,1983

• Nagata H,Miyata S,et al:Heavy metal concentrations in blood cells in patients with amyotrophic lateral sclerosis.J Neurol Sci 67:173,1985
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• 勝井義和,永田博司,宮田学ほか:筋萎縮性側策硬化症(ALS)患者の赤血球中重金属濃度-三重県における5症例の検討-,臨床神経学 27:19,1987

• 野呂瀬昇,荒井克幸:長期静脈栄養法(TPN)幼児例におけるマンガン欠乏症の検討,JJPEN 9:978,1987

• Mirowitz SA,Westrich TJ,Hirsch JD:Hyperintensity basal ganglia on T1-weighted MR Images in patients receiving parenteral nutrition.Radiology 181:117,1991
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• Ejima A,Imamura T et al:Manganese intoxication during total parenteral nutrition.Lancet 339:426,1992
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• Takeda A:Brain function and manganese.Biomed Res Trace Elements 12:188,2001

• Takagi Y et al:Evaluation of indexes of in vivo manganese status and the optimal intravenous dose for adults undergoing home parenteral nutrition.Am J Clin Nutr 75:112,2002
  pubmed

P.17 掲載の参考文献

• Pharoah POD et al:Neurological damage to the fetus resulting from revere iodine deficiency during pregnancy.Lancet 1:308,1971

• WHO.Micronutrient Deficiency Information System(MDIS)Working Paper No.1.Grobal prevalence of iodine deficiency disorders.Geneva:WHO/UNICEF/ICCIDD,1993

• WHO,UNICEF,ICCIDD:Assessment of iodine deficiency disorders and monitoring their elimination:A guide for programme managers.2nd ed,WHO,Geneva,p7,2001,p7

• 飯高誠:ヨード欠乏症とその臨床の実際,日本医師会雑誌 129:621,2003

P.18 掲載の参考文献

• Smith SE et al:Cobalt and vitamin B12 in ruminant nutrition. A review.J Dairy Sci 40:1215,1957

• Schroeder HA et al:Essential trace metals in man,cobalt.J Chron Disease 20:869,1967

• Hines JD et al:The hematological complications following partial gastrectomy:A study of 292 patients.Am J Med 43:555,1967
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• Carmel R:Nutritional vitamin B12 deficiency.Ann Intern Med 88:647,1978
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• McRaetd et al:Why vitamin B12 deficiency should be managed aggressively.Geriatrics 44:70,1989
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• Stabler SP et al:Clinical diagnosis of cobalamin deficiency.Blood 76:871,1990
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• 木村修一:微量元素の必須性,最新医学 45:808,1990
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• Schroeder HA et al:Chromium deficiency as factor in atherosclerosis.J Chron Dis 23:123,1970
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• Jeejeebhoy KN et al:Chromium deficiency,glucose intolerance,and neuropathy reversed by chromium supplementation.:In a patient receiving long-term total parenteral nutrition. Am J Clin Nutr 30:531,1977

• Anderson RA et al:Serum chromium of human subjects;Effects of chromium supplementation and glucose.Am J Clin Nutr 41:571,1985
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• Anderson RA,Kozlovsky AS:Effects of supplemental chromium on patients with symptoms of reactive hypoglycemia.Metabolism 36:351,1987

• Moukarzel AA et al:Excessive chromium intake in children receiving total parenteral nutrition.Lancet 339:385,1992
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• Mertz W:Chromium in human nutrition.;A review.J Nutr 123:626,1993
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• Anderson RA et al:Elevated intake of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.Diabetes 46:1786,1997
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• 林洋一,朝岡昭,荒川泰行ほか:インスリン抵抗性が考えられる2型糖尿病におけるクロム補給の効果,Biomed Res Trace Elements 12:307,2001
  Medical*Online

P.19 掲載の参考文献

• Richhert DA,Westerfeld WW:Isolation and identification of the xanthine oxidase factor as molybudenum.J Biol Chem 203:915,1953

• Cohen HJ et al:Hepatic sulfite oxidase.A functional role for molybudenum.J Biol Chem 246:374,1971

• Johnson JL et al:Characterization of the molybudenum cofactor of sulfite oxidase.Xanthine oxidase and nitrate reductase.Identification of a pteridine as a structural component.J Biol Chem 255:1783,1980

• Theodora A et al:Molybdenum in the diet:an estimate of average daily intake in the United States.Am J Clin Nutr 33:1103,1980

• Abumrad NN et al:Amino acid intolerance during prolonged total parenteral nutrition reversed by molybudate therapy.Am J Clin Nutr 34:2551,1981
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• Turnlund JR et al:Molybudenum absorption,secretion and retention studied with stable isotopes in young men during depletion and repletion.Am J Clin Nutr 61:1102,1995

• 鈴木和春:機能性栄養素としての微量元素と食物・サプリメント,治療 88:1886,2006
  Medical*Online

第2章 亜鉛の体内分布と1日必要量

P.20 掲載の参考文献

• Todd WR,Elvehjem CA,Hart EB:Zinc in the nutrition of the rat.Am J Physiol 107:146,1934

• Tucker HE,Salmon WD:Parakeratosis on zinc deficiency disease in the pig.Proc Soc Exp Med 88:613,1955

• O'Dell BL et al:Significance of dietary zinc for the growing chicken.J Nutr 65:603,1958

• Prasad AS:Nutritional metabolic role of zinc.Fed Proc 26:172,1967

• 石原信夫:Zn 動態と疾病,臨床科学 9:825,1973

• 山根靖弘:生体における微量金属の役割と亜鉛の代謝と生理について,微量金属代謝1:1,1975

• 渥美利行:各種疾患における血清亜鉛値と硫酸亜鉛による治療成績,微量金属代謝1:19,1975

• Davies S:Assessment of zinc status.Intl Clin Nutr Rev4:122,1984.

• Fitzgerald FT et al:Trace metals in human disease.Adv Intern Med 30:337,1984
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• Vallee BL et al:The biochemical basis of zinc physiology.Physiol Rev 73:79,1993
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• Prasad AS:Zinc;An overview.Nutrition 11:93,1995
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• McClain C et al:Zinc and endothelial function.Nutrition 11:117,1995
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• Sandstrom B:Bioavailability of zinc.Eur J Clin Nutr 51 (suppl 1): S17,1997

• Wastney ME et al:Kinetics of zinc metabolism;Variation with diet,genetics and disease.J Nutr 130:1355S,2000

• King JC,Klein CL:Zinc.In Modern Nutrition in Health and Disease.(Shils ME et al),Lippincott,Philadelphia p223,2000

• 柳澤裕之:亜鉛の生理,治療(別冊) 87:4,2005

• 柳澤裕之ほか:亜鉛の生理,老年消化器病 19:61,2007

• 宮田學:高齢者の亜鉛欠乏症,日本老年医学会雑誌 44:607,2007

• 田中久:必須微量元素・亜鉛-細胞形成と免疫に欠かせないミネラル-,山本英夫編,糖鎖の健康学,ライフストーン社,2007,109

• 宮田學:高齢者の亜鉛欠乏症,老年医学UPDATE 2008-2009,メジカルビュー社,2008,143

P.22 掲載の参考文献

• Donnes ER,Wormall A:The zinc content of erythrocytes and leucocytes of blood from normal and leukaemic subjects.Biochem J 78:578,1961

• Chang TL et al:Determination of magnesium and zinc in human brain tissue by atomic absorption spectroscopy.Anal Chem Acta 34:17 1966

• Foly B et al:Zinc content of human platelets.Proc Soc Exp Biol Med 128:256,1968

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• 宮田学,奥野資夫,島村佳成,三宅健夫:老年者における亜鉛の吸収と排泄,日本老年医学会雑誌 24:272,1987

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• 深田俊幸:亜鉛トランスポーターS1c39a13/Zip13 の結合組織発生における役割とヒト遺伝性疾患の関与,Biomed Res Trace Elements 20:153,2009

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• 西牟田守:微量元素の食餌摂取基準(2005年版)について,Biomed Res Trace Elements 19:3,2008

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第3章 亜鉛の生理作用

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• 坂井和男,山根靖弘:金属と核酸,代謝 20:605,1983

• Klug A,Rhodes D:"Zinc fingers":A novel protein motif for nucleic acid recognition.Trends Biochem Sci 12:461,1987

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• 出射靖生:創傷時の亜鉛代謝に関する研究,関西医科大学雑誌 28:772,1976

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• 荒川泰昭,小川康恭,荒記俊一:微量元素と免疫機能,臨床検査 53:191,2009

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• 森田昌俊:メタロチオネインとその生物学的役割,代謝 20:23,1983

• Hammer DH:Metallothionein.Ann Rev Biochem 55:913,1986

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第4章 亜鉛欠乏症

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• 児玉浩子:新生児・小児の微量元素の栄養状態の評価とその臨床,治療 88:1896,2006
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第5章 疾患と亜鉛

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• 池田稔:耳鼻咽喉科領域と亜鉛,消化器の臨床 2:85,1999

• 池田稔:微量元素欠乏性感覚器障害とその臨床の実際,日本医師会雑誌 129:643,2003

• 池田稔,生井明浩:味覚障害と亜鉛欠乏,Biomed Res Trace Elements 18:10,2007
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• 武田憲昭:亜鉛酵素「アンギオテンシン変換酵素」活性比と味覚障害患者の亜鉛栄養状態の評価,Biomed Res Trace Elements 20:149,2009
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• Harrison WW et al:Trace elements in human brain;Copper,zinc,iron and magnesium.Clin Chim Acta 21:55,1968
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• 宮田学,亀山正邦:変性神経疾患における微量元素,神経内科 13:9,1980

• 宮尾益英:小児科領域における微量元素-特に銅および亜鉛について-,日本小児科学会誌 85:1271,1981

• Fredrickson CJ:Neurobiology of zinc and zinc containing neuirons.Int Rev Neurobiol 31:145,1989

• 大石実,高須俊明:神経疾患と微量元素,最新医学 45:657,1990
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• Shiraki H,Yase Y:Amyotrophic lateral sclerosis and Parkinson-dementia in the Kii peninsula;Comparison with the same disorder in Guam and with Alzheimer's disease.Handbook of Clinical Neurology 15:273,1991

• Choi DW,Koh JY:Zinc and brain injury.Annu Rev Neurosci 21:347,1998
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• Colvin RA et al:Zinc transport in the brain;Routes of zinc influx and efflux in neurons.J Nutr 130:1484S,2000
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• Frederickson CJ et al:Importance of zinc in the central nervous system;The zinc containing neuron. J Nutr 130:1471S,2000

• Takeda A,Minami A,Oku N:Neuromodulatory action of zinc in the release of neurotransmitters. Biomed Res Trace Elements 14:287,2003

• 中山明弘ほか:ハーブエッセンシャルオイルの活性酸素種の消去能と生体反応,Aroma Res 18:123,2004

• Maylor EA,Simpson EE,Secker DL et al:Effects of zinc supplementation on cognitive function in healthy middle-aged and older adults.Br J Nutr 96:752,2006
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• Pffeifer CC,Iliev V:Zinc deficiency and copper excess in the schizophrenias.Int Rev Neurobiol (supple)1:141,1972

• Greiner AC,Chan SC,Nicolson GA:Human brain contents of calcium,copper,magnesium,and zinc in some neurological pathologies.Clin Chim Acta 64:211,1975
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• Henkin RI:A syndrome of acute zinc loss.Cerebellar dysfunction,mental changes,anorexia and smell dysfunction.Arch Neurol 32:745,1975
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• Casper RC et al:An elevation of trace metals,vitamins and taste function in anorexia nervosa.Am J Clin Nutr 33:1801,1980

• Hansen CR Jr et al:Copper and zinc deficiencies in association with depression and neurological fi ndings.Biol Psychiatry 18:395,1983

• 木村潔,久村静司,錦織壮:破瓜型分裂病に対するかき肉エキスの臨床効果(第一報),微量栄養素研究 2:153,1985

• 錦織壮ほか:破瓜型分裂病に対するかき肉エキスの臨床効果並びに亜鉛,銅代謝について(第二報),微量栄養素研究 3:79,1986

• Nakai Y et al:Taste function in patients with anorexia nervosa and bulimia nervosa.International J Eating Disorders 6:257,1987

• Nishigori T,Kimura K:Supplementary effect of oyster extract on depressed patients under treatment with antidepressants.Trace Nutrients Res 4:203,1988

• McLoughlin IJ,Hodge SJ:Zinc in depressive disorder.Acta psychiatr Scand 82:451,1990

• Andrews RCR:Unification of the findings in schizophrenia by reference to the effects of gestational zinc deficiency.Med Hypotheses 31:141,1990

• Kornhuber J et al:Iron,copper,zinc,magnesium,and calcium in postmortem brain tissue from shizophrenic patients.Biol Psychiatry 36:31,1994

• Maes M et al:Hypozincemia in depression.J Affect Disord 31:135,199494

• Maes M,Vandoolaeghe E,Neels H et al:Lower serum zinc in major depression is a sensitive marker of treatment resistance and of the immune/inflammatory response in that illness.Biol Psychiatry 42:349,1997
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• Maes M et al:Lower serum zinc in major depression in relation to changes in serum acute phase proteins.J Affect Disord 56:189,1990

• Shay NF,Mangian HF:Neurobiology of zinc-influenced eating behavior.J Nutr 130:1493S,2000
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• Nowak G et al:Effect of zinc supplementation on antidepressant therapy in unipolar depression;A preliminary placebo-controlled study.Pol J Pharmacol 55:1143,2003
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• 小野あゆみ,南豊彦,中川のぶ子ほか:味覚低下症例とうつ病,耳鼻と臨床 50:328,2004

• Nowak G,Szewezyk B,Pilk A:Zinc and depression.An update.Pharmacological Reports 57:713,2005

• 大田共夫ほか:C型肝炎に併発し亜鉛補充療法が奏効した治療抵抗性うつ病の1症例, 臨床精神薬理 8:489,2005

第6章 老化と亜鉛

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• Garry PJ et al:Nutritional status in a healthy elderly population;Dietary and supplemental intakes.Am J Clin Nutr 36:319,1982

• Garfinkel D:Is aging inevitable?The intracellular zinc deficiency hypothesis of aging.Med Hypothesis 19:117,1986

• 山口賢次:加齢と微量元素,最新医学 45:753,1990
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• Sandstead HH:Is zinc deficiency a public health problem?Nutrition 11:87,1995
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• 後藤真:遺伝性ヒト老化モデル-Werner症候群-,医学のあゆみ 188:80,1999

• 高橋良哉:微量元素と老化,Biomed Res Trace Elements 15:326,2004
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• 柳澤裕之:生命と微量元素-なぜ生体に微量元素は必要なのか-,治療 88:1839,2006
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• 荒川泰行ほか:高齢者と亜鉛,老年消化器病 19:53,2007

• 宮田學:高齢者の亜鉛欠乏症,日本老年医学会誌 44:677,2007

P.99 掲載の参考文献

• Vikbladh I:Studies on zinc in blood.Scand J Clin Lab Invest 3:1,1951
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• Pekarek RS et al:Serum zinc,iron and copper concentrations during typhoid fever in man;Effect of chloramphenicol therapy.Clin Chem 21:528,975

• Bogden JD:Effect of pulmonary tuberculosis on blood concentrations of copper and zinc.Am J Clin Pathol 67:251,1977
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• Duchateau J et al:Beneficial effects of oral zinc supplementation on the immune response of old people.Am J Med 70:1001,1981
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• Allen JI et al:Alteration in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency.J Lab Clin Med 102:577,1983
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• 関口隆憲:微量元素と易感染性,小児医学 25:267,1992

• Losourd BM:Nutrition and immunity in the elderly:Modification of immune responses with nutritional treatments.Am J Clin Nutr 66:4785,1997

• Shankar AH,Prasad AS:Zinc and immune function:The biological basis of altered resistance to infection.Am J Clin Nutr 68(suppl):447s,1998

• Baum MK et al:Zinc status in human immunodeficiency viral infection.J Nutr 130:1421S,2000
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• Prasad AS,Beck FWJ et al:Zinc supplementation decreases incidence of infections in the elderly:Effect of zinc on generation of cytokines and oxidative stress.Am J Clin Nutr 85:837,2007
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• Ukita T,Oidov B et al:Serum zinc deficiency increases susceptibility to infection in older patients who have long-term hospitalizations.Biomed Res Trace Elements 19:260,2008

P.100 掲載の参考文献

• Olson KB et al:Trace element content of cancerous and noncancerous human liver tissues.Science 119:772,1954
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• Poswillo CE et al:Inhibition of carcinogenesis by dietary zinc.Nature 231:447,1956

• Yamaguti H et al:Zinc metabolism in malignant tumor(1),Gann 51(Suppl):18,1960

• 三枝達明:担癌生体の亜鉛代謝に関する研究,大阪医誌 8:11,1966

• 高野喜久雄ほか:癌患者の血清銅および亜鉛について,癌の臨床 5:797,1969

• 白石忠雄ほか:亜鉛代謝に関する研究・消化器疾患および悪性腫瘍を中心として,日本内科学会誌 57:942,1968

• Danielson A,Steinnes E:A study of some selected trace elements in normal and cancerous tissue by neutron activation analysis.J Nucl Med 11:260,1970

• 辻秀男ほか:担癌生体における亜鉛の意義,日本外科学会誌 71:1393,1970

• Wright EB et al:Liver zinc in carcinoma.Nature 237:166,1972
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• Alexander FW et al:Plasma copper and zinc in acute leukemia.Arch Dis Child 47:671,1972
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• Dalves HT et al:Copper and zinc concentration in the plasma of leukemic children.Br J Haematol 24:525,1973

• Griffith K et al:Tissue zinc in malignant disease.Nature 241:60,1973
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• Pories WJ et al:Trace elements that act to inhibit neoplastic growth.Ann N.Y.Acad Sci 199:265,1977

• Inutsuka S et al:Plasma copper and zinc levels in patients with malignant tumors of digestive organs.Cancer 42:626,1978
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• Gregoriadis GC et al:A comparative study of trace elements in normal and cancerous colorectal tissues,Cancer 52:508,1983
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• 山本恵子:悪性腫瘍と微量元素,小児医学 25:251,1992

• 斉藤和雄:予防医学からみた微量元素-とくに成人病と微量元素-,Biomed Res Trace Elements 7:9,1996

• 小山洋:必須微量元素による発がん抑制効果とそのメカニズム,日本臨床 54:52,1996
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• Ebara M, Fukuda H,Hatano R et al:Relationship between copper,zinc and metallothionein in hepatocellular carcinoma and its surrounding liver parenchyma.J Hepatol 33:415,2000
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• Kuo HW,Chen SF,Wu CC et al:Serum and tissue trace elements in patients with breast cancer in Taiwan.Biol Trace Elem Res 89:1,2002
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• Cunzhi H,Jiexian J et al:Serum and tissue levels of six trace elements and copper/zinc ratio in patients with cervical cancer and uterine myoma.Biol Trace Elem Res 94:113,2003
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• 福田浩之ほか:微量元素と癌,日本医師会雑誌 129:646,2003

• 荒川泰昭:癌免疫と微量元素,Biomed Res Trace Elements 15:317,2004
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• 江原正明,岡部真一郎ほか:肝細胞癌症例における銅蓄積の意義,Biomed Res Trace Elements 16:25,2005
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P.102 掲載の参考文献

• Haumont S:Distribution of zinc in bone tissue.J Histochem Cytochem 9:141,1961
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• Kenndy ED et al:Zinc.Its relationship to osteoporosis in rheumatoid arthritis.Scand J Rheumatol 4:243,1975

• Brown ED et al:Bone mineralization during a developing zinc deficiency.Proc Soc Exp Biol Med 157:211,1978
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• 岡野登志夫:骨代謝回転に及ぼす必須微量元素の影響,日本臨床 54:148,1996
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• 山口正義:骨代謝調節における亜鉛の役割と機構-骨病態修復へのアプローチ-,Biomed Res Trace Elements 13:90,2002
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• 山口正義:骨代謝回転に及ぼす微量元素とその生体調節,治療 88:1964,2006
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P.104 掲載の参考文献

• Mulholland JH et al:Protein metabolism and bedsores.Ann Surgery 118:1015,1943

• Brewer RD et al:The effect of oral zinc sulphate on healing of decubitus ulcers in spinal cord injured patient.Ann Clin Spinal Cord Injured Conference 70:2,1967

• Cohen C:Zinc sulphate and bedsores.Br Med J 2:561,1968
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• Abbot DF et al:Zinc sulphate and bedsores.Br Med J 2:763,1968

• Norris JR,Reynord RE:The effects of oral zinc sulphate thwrapy on decubitus ulcer.J Am Geriatr Soc 19:793,1971

• McBean LD et al:Serun zinc and alpha2-macroglobulin concentration in myocardial infarction,decubitus ulcer,multiple myeloma,prostatic carcinoma,Down's syndrome and nephritic syndrome.Clin Chim Acta 50:43,1974

• 岡田淳:褥瘡患者における血清亜鉛の動態,微量金属代謝 1:43,1975

• 岡田淳,小酒井望,只野寿太郎ほか:硫酸亜鉛による褥瘡の治療,微量金属代謝 2:55,1976

• 清水幸雄,稲田潔:創傷治癒における亜鉛の意義,微量金属代謝 4:21,1977

• William CM:Iron and zinc status in multiple sclerosis patients with pressure sores.Eur J Clin Nutr 42:321,1988

• Chernoff RS et al:The effect of a very high protein liquid formula on decubitus ulcer healing in long-term tubefed institutionalized patients.J Am Dietetic Assoc 90:A-130,1990

• Stephen J et al:Arginine stimulates wound healing and immune function in elderly human beings.Surgery 114:155,1993

• 田中結華,奥田豊子,福田みゆきほか:褥瘡を持つ寝たきり高齢者の栄養評価に関する研究,微量栄養素研究 16:165,1999

• Kohn S et al:Effect of zinc supplementation on epidermal Langerhans' cells of elderly patients with decubitus ulcers.J Dermatol 27:258,2000
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• Mino Y et al:Risk factors for pressure ulcers in bedridden elderly subjects:Importance of turning over in bed and serum albumin level.Geriatrics and gerontology 1:38,2001

• 田中芳明,ほか:創傷治癒促進因子を用いた褥瘡患者の栄養管理-2症例の治療報告.日本臨床外科学会雑誌 63:1633,2002

• 志越顕,上野ゆん子,熊谷頼佳:褥瘡と栄養検査-微量元素の重要性も含めて-,臨床病理レビュー 127:92,2003

• 湧上聖:褥瘡と亜鉛,治療(別冊) 87:88,2005

• 石澤美保子,奥田豊子,阿曽洋子:褥瘡患者における食事摂取内容・亜鉛摂取量と創治癒状況との関連,日本褥瘡学会誌 8:133,2006
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• 美濃良夫:褥瘡治療と栄養管理,医学のあゆみ 18:543,2006

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• Goodwin JS et al:Association between nutritional status and cognitive functioning in a healthy population.JAMA 249:2917,1983

• Prohaska JR:Functions of trace elements in brain metabolism.Physiol Rev 67:858,1987
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• Tucker DM et al:Nutrition status and brain function in aging.Am J Clin Nutr 52:93,1990
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• Uchida Y et al:The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein?like protein.Neuron 7:337,1991
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• Bush AI et al:Rapid induction of Alzheimer A βamyloid formation by zinc.Science 265:1464,1994

• 川原正博,黒田洋一郎:アルツハイマー病と微量金属,老年精神医学 6:1105,1995
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• Lovell MA et al:Protection against amyloid beta peptide toxicity by zinc.Brain Res 823:88,1999
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• Huang X et al:Alzheimer's disease,β-amyloid protein and zinc.J Nutr 130:1488S,2000

• Saito T,Kurosaki M,Numata T et al:Zinc and functional impairment of the brain associated with aging. Biomed Res Trace Elements 12:179,2001

• 石原良子ほか:細胞内金属元素の分布異常からみた神経細胞の変性-アルツハイマー病を例として-,Biomed Res Trace Elements 14:204,2003
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• Morris MC,Evans DA et al:Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease.Arch Neurol 60:940,2003

• Stoltenberg M et al:Immersion autometallographic tracing of zinc ions in Alzheimer β-amyloid plaques.Histochem Cell Biol 123:605,2005

• Adrlard PA,Bush AI:Metals and Alzheimer's disease.J Alzheimers Dis 10:145,2006
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• Maylor EA,Simpson EE,Secker DL et al:Effects of zinc supplementation on cognitive function in healthy middle-aged and older adults.Br J Nutr 96:752,2006
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• Kawahara M:Neurotoxicity of trace elements and the pathogenesis of senile-type dementia.Biomed Res Trace Elements 19:25,2008

• Bahnham KJ,Bush AI:Metals in Alzheimer's and Parkinson's disease.Curr Opin Chem Biol 12:222,2008

• 橋本道男,山下一也:食事で防ぐ認知症-特に魚摂取との関連-,最新精神医学 13:75,2008

• 橋本道男:アルツハイマー病と食事栄養,Trace Nutrients Research 25:8,2008

• 宮嶋裕明:神経変性病における微量金属の役割,細胞工学 27:246,2008