書籍名 |
診断と治療のABC101/高LDL―C血症・低HDL―C血症 |
出版社 |
最新医学社
|
発行日 |
2015-01-25 |
著者 |
|
ISBN |
|
ページ数 |
228 |
版刷巻号 |
101 |
分野 |
|
シリーズ |
最新医学 別冊
|
閲覧制限 |
未契約 |
近年の食生活の変化に伴い脂質異常症患者が増えており,特にLDL-Cの増加やHDL-Cの減少は,動脈硬化性疾患の原因と考えられています。本誌ではコレステロール代謝異常や動脈硬化発症に関する基礎的な病態生理から,最新の診断法,種々の薬剤,補助療法に関する管理治療法が網羅されております.是非ご一読ください。
目次
- 表紙
- 序
- 目次
- MAP 眼で見る高LDL - C血症・低HDL - C血症
- 第1章 概念・定義と疫学
- 高LDL - C血症と低HDL - C血症の概念と病型分類
- 高LDL - C血症, 低HDL - C血症, 高HDL - C血症の臨床疫学
- 第2章 病理・病態生理
- 脂質異常症による動脈硬化の病理
- コレステロール代謝異常の病態生理
- 1. リポタンパク受容体
- 2. 転写因子SREBPと核内受容体
- 3. コレステロール吸収
- 4. コレステロール逆転送系
- 5. LDLRAP1, PCSK9
- 6. 植物ステロール・酸化コレステロール
- 動脈硬化惹起性リポタンパクの代謝
- 1. 酸化LDL
- 2. small dense LDL
- 第3章 診断
- 診断のすすめ方
- LDL - C測定法の現状と将来の課題
- HDL検査 ( 量と質に関して )
- コラム 特定健診の現状と課題 ( 公衆衛生医師の立場から )
- 第4章 管理・治療
- 高LDL - C血症と低HDL - C血症の管理・治療
- 高LDL - C血症と低HDL - C血症の薬物療法の基準
- 治療薬剤
- 1. スタチン
- 2. エゼチミブ
- 3. フィブラート, チアゾリジン誘導体
- 4. プロブコール, 陰イオン交換樹脂製剤 ( レジン )
- 5. イコサペント酸エチル ( EPA ) 製剤, ドコサヘキサエン酸 ( DHA ) 製剤, ニコチン酸製剤
- 補助療法 LDLアフェレシス
- プラークの退縮とLDL - C, HDL - C
- CETP阻害薬の現状
- 奥付
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第1章 概念・定義と疫学
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第2章 病理・病態生理
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第3章 診断
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第4章 管理・治療
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