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未契約
書籍名 診断と治療のABC101/高LDL―C血症・低HDL―C血症
出版社 最新医学社
発行日 2015-01-25
著者
  • 倉林正彦(企画)
ISBN
ページ数 228
版刷巻号 101
分野
  • 臨床医学:一般
  • 雑誌
シリーズ 最新医学 別冊
閲覧制限 未契約

近年の食生活の変化に伴い脂質異常症患者が増えており,特にLDL-Cの増加やHDL-Cの減少は,動脈硬化性疾患の原因と考えられています。本誌ではコレステロール代謝異常や動脈硬化発症に関する基礎的な病態生理から,最新の診断法,種々の薬剤,補助療法に関する管理治療法が網羅されております.是非ご一読ください。

目次

  • 表紙
  • 目次
  • MAP 眼で見る高LDL - C血症・低HDL - C血症
  • 第1章 概念・定義と疫学
    P.14閲覧
    • 高LDL - C血症と低HDL - C血症の概念と病型分類
    • 高LDL - C血症, 低HDL - C血症, 高HDL - C血症の臨床疫学
  • 第2章 病理・病態生理
    P.30閲覧
    • 脂質異常症による動脈硬化の病理
    • コレステロール代謝異常の病態生理
      • 1. リポタンパク受容体
      • 2. 転写因子SREBPと核内受容体
      • 3. コレステロール吸収
      • 4. コレステロール逆転送系
      • 5. LDLRAP1, PCSK9
      • 6. 植物ステロール・酸化コレステロール
    • 動脈硬化惹起性リポタンパクの代謝
      • 1. 酸化LDL
      • 2. small dense LDL
  • 第3章 診断
    P.112閲覧
    • 診断のすすめ方
    • LDL - C測定法の現状と将来の課題
    • HDL検査 ( 量と質に関して )
    • コラム 特定健診の現状と課題 ( 公衆衛生医師の立場から )
  • 第4章 管理・治療
    P.137閲覧
    • 高LDL - C血症と低HDL - C血症の管理・治療
      • 1. 食事療法
      • 2. 運動療法
    • 高LDL - C血症と低HDL - C血症の薬物療法の基準
    • 治療薬剤
      • 1. スタチン
      • 2. エゼチミブ
      • 3. フィブラート, チアゾリジン誘導体
      • 4. プロブコール, 陰イオン交換樹脂製剤 ( レジン )
      • 5. イコサペント酸エチル ( EPA ) 製剤, ドコサヘキサエン酸 ( DHA ) 製剤, ニコチン酸製剤
    • 補助療法 LDLアフェレシス
    • プラークの退縮とLDL - C, HDL - C
    • CETP阻害薬の現状
  • 奥付

参考文献

第1章 概念・定義と疫学

P.21 掲載の参考文献

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第2章 病理・病態生理

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第3章 診断

P.118 掲載の参考文献

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第4章 管理・治療

P.143 掲載の参考文献

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