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I. 実験動物の純化と品質管理

P.7 掲載の参考文献

• 1) 安東洪次 : わが国の実験動物の現状について. 実験動物 7, 3-4, 1958.

• 2) 吉田俊秀 : 新しい実験動物. 癌と化学療法 4, 675-681, 1977.
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• 3) 近藤恭司 : 実験動物と系統. 癌と化学療法 4, 869-874, 1977.
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• 4) 川俣順一 : 疾患モデル. 癌と化学療法 4, 1113-1131, 1977.
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• 5) 川俣順一 : 医学のモデルとして実験動物の開発と問題点. 学術月報 29, 385-397, 1976.

• 6) 川俣順一 : がん研究と実験動物. 実験動物の開発 (田嶋嘉雄編), 医歯薬出版, 東京, 1977, pp.1-25

• 7) 川俣順一, 松下 宏編 : 疾患モデル動物ハンドブック. 医歯薬出版, 東京, 1979.

P.23 掲載の参考文献

• 1) Klein, J. : Biology of the Mouse Histocompatibility 2 Complex. Springer-Verlag. 1975.

• 2) Morse III, H.C. (ed) . : Origins of Inbred Mice. Academic Press 1978.

• 3) Foster, H.L., Small, J, D. and Fox, J. G. (eds.) : The Mouse in Biomedical Research. Vol.I. Academic Press, 1981.

• 4) 森脇和郎 : 実験用マウスの起源と発展. 自然 36, 58-68, 1981.

• 5) Staats, J. : Standard nomenclature of inbred strains of mice : Seventh listing. Cancer Research 40, 2083-2128, 1980.
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• 6) Altman, P.L. and Katz, D.D. (eds.) : Inbred and Genetically Defined Stranis of Laboratory Animals. Part 1. Mouse and Rat. Biological Handbook III. Federation of American Societies for Experimental Biology, Maryland 1979.

• 7) Green, M.C. (ed) . : Genetic Variants and Strains of the Laboratory Mouse. Gustav Fischer Verlag, Stuttgart & N.Y.,1981.

• 8) Shiroishi, T., Sagai, T. and Moriwaki, K. : A simplified micro-method for cytotoxicity testing using, a flat-type titration plate for the detection of H-2 antigens. Microbiol. Immunol 25, 1327-1334. 1981.
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• 9) Yoshida, M.C., Ikeuchi, T. and Sasaki, M : Differential staining of parental chromosomes in interspecific cell hybrids with a combined quinacrine and 33258 Haechst technique. Proc. Jpn. Acad. 51, 184-187, 1975.

P.31 掲載の参考文献

• 1) 吉田俊秀, 牧野佐二郎 : ネズミの繋殖に関する研究 4. 北大理学部におけるシロネズミおよびハツカネズミの系統とその特徴. 山階鳥類研報 5, 185-193, 1954.

• 2) King, H.D. : Studies on inbreeding, I. The effects of inbreeding on the growth and variability in the body weight of the albino rat. J. Exp. Zool., 27, 1-35, 1918.

• 3) Maekawa, A. and Odashima, S. : Spontaneous tumors in ACI/N rats. J. Natl. Cancer Inst. 55, 1437-1441, 1975.

• 4) Hansen, C.T. et al : Catalogue of NIH Rodents National Institutes of Health, Bethesda, Maryland. DHEW Publication No. (NIH) 74-606, 1973.

• 5) Festing, M.F.W. : Inbred Strains in Biomedical Research. MacMilan Press LTD., London 1979.

• 6) 実験動物特別委員会編 : 「がん研究に用いられる実験動物」 (代表 西塚泰章), 1981.

• 7) Burek, J.D. and Hollander, C. F. : Studies on spontaneous lesions in ageing BN/Bi rats, I Neoplastic and non-neoplastic lesions. 1975 Ann. Rep. Organization for Health Research, TNO, Rijswijk, pp.235-237, 1975.

• 8) Lindsay, S. et al : Naturally occurring thyroid carcioma in the rat. Similarities to human medullary carcinoma. Arch. Pathol., 86, 353-364, 1968.

• 9) Sass, B. et al : Incidence of spontaneous neoplasms in F 344 rats throughout natural lifespan. J. Natl. Cancer Inst. 54, 1449-1456, 1975.

• 10) Hall, C.E. et al : Immunity of Fischer 344 rats to salt hypertension. Life. Sci. 18, 1001-1008, 1976.
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• 11) Esber, H.J. et al : Variation in serum hormone concentrations in different rat strains. Proc. Soc. Exp. Biol. Med. 146, 1050-1053, 1974.
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• 12) Schemmel, R. et al : Dietary obesity in rats : body weight and body fat accretion in seven strains of rats. J. Nutrition. 100, 1041-1048, 1970.
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• 13) McFarin, D.E. et al : The immune response aganinst an encephalitogenic fragment of guinea-pig basic protein in the Lewis and Brown Norway Strains of rat. J. Immunol, 115, 1456-1458, 1975.

• 14) Friedman, I. et al : Experimental myocarditis : enhancement by the use of pertussis vaccine in Lewis rats. Experientia 26, 1143-1145, 1970.

• 15) Bazin, H. : Inbred strains. Rat News Letter 1, 27-29, 1977.

• 16) Bazin, H. et al : Transplantable immunoglobulin-secreting tumors in rats. I. General features of LOU/Wsl strain rat immunocytomas and their monoclonal proteins. Int. J. Cancer 10, 568-580, 1972.

• 17) Yosida, T.H. : Studies on the karyotype differentiation of the Norway rat. I. Translocation bentween the pair nos. 1 and 12 chromosomes in the Lewis-strain rat. Proc. Jpn Acad. 56 (B), 268-272, 1980,

• 18) Yosida, T.H. : Ibid., II. A mosaic rat carrying the translocation and inversion of pair no. 1 chromosomes with a note on their transmission to offspring. Proc. Jpn Acad. 56 (B), 322-327, 1980.

• 19) Yosida, T.H. : Ibid., III. Segregation of offspring from the 1/12 translocation heterozygotes and fertility of the translocation homozygotes. Proc. Jpn Acad. 56 (B), 437-442, 1980.

• 20) Yosida, T.H. : Ibid., IV. Segregation and fertility of the Norway rats with inversion pair no.1. Jpn. J. Genet. 55, 397-403, 1980.

• 21) Yosida, T.H. : Ibid., V. Hypotrichotic mutant rats appeared in the inversion stock (LEM) . Proc. Jpn. Acad. 57 (B), 29-34, 1981.

• 22) 吉田俊秀, 栗田義則, 種田信司 : 三島市内外で捕獲された2変異ラットとその遺伝 (実験用小動物の繁殖と遺伝に関する研究. 予報2). 実験動物 10, 20-22, 1961.

• 23) Sallman, L. von and Grimes, P. : Spontaneous retinal degeneration in mature Osborne-Mendel rats. Arch. Opthal. 88 : 404-411, 1972.

• 24) Okamoto, K. : Spontanous hypertension in rats. In International Review of Experimental Pathology Vol.7 (ed. Richter, G.W. and Epstein M. A.), Acad. Press, New York, pp.227-270, 1968.

• 25) Nagaoka, A., Iwatsuka, H., Suzuki, Z. and Okamoto, K. : Genetic predisposition to stroke in spontaneous hypertensive rats. Am. J. Pathol. 230, 1354-1359, 1976.

• 26) Boorman, G.A. et al : Naturally occurring medullary thyroid carcinoma in the rat. Arch. Pathol. 94, 35-41, 1972.
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• 27) Kim, U. et al : A highly inbred strain of Wistar rats yielding spontaneous mammosomatotropic pituitary and other tumors. J. Natl. Cancer Inst. 24, 1031-1047, 1960.

• 28) Yosida, T.H. and Amano, K. : Autosomal polymorphism in laboratory bred and wild Norway rats, Rattus Norvegicus, found in Misima. Chromosoma (Berl.) 16, 658-667, 1965.

• 29) 吉田俊秀 : ウィスター系ラットの由来と利用および染色体調査. 実験動物 28, 144-156, 1979.

P.40 掲載の参考文献

• 1) 文部省モニタリング研究班 (研究代表者, 野村達次) : 実験動物の品質基準の作成及び検査方法の確立に関する研究. 報告書, 1980.

• 2) Whittingham, D.G. : Embryo banks in the future of developmental genetics. Genetics, (Suppl.) 78, 395-402, 1974.

• 3) Muhlbock, O. (ed) : Proceedings of the Workshop on Basic Aspects of Freeze Preservation of Mouse Strains. Gustav Fischer Verlag, Stuttgart, 1976.

• 4) Zeilmaker, G.H. (ed) : Proceedings of the Workshop on Frozen Storage of Laboratory Animals. Gustav Fischer Verlag, Stuttgart, 1981.

• 5) Elliot, K. and Whelan, J. (eds) : The Freezing of Mammalian Embryos. (Ciba Found. Symp. No.52 (new series)), Elsevier/North-Holland, Amsterdam, 1977.

• 6) Whittingham, D.H., Leibo, S.P. and Mazur, P. : Survival of mouse embryos frozen to-196°and-269°C.Science, 178, 411-414, 1972.

• 7) Wilmut, I. : The effect of cooling rate, warming rate, cryoprotective agent and stage of development on survival of mouse embryos during freezing and thawing. Life Sciences, 11, 1071-1079, 1972.

• 8) Whittingham, D.G. : The viability of frozen-thawed mouse blastocysts. J. Reprod. Fert., 37, 159-162, 1974.

• 9) Whittingham, D.G. and Whitten W. K. : Long-term storage and aerial transport of frozen mouse embryos. J. Reprod. F : fert., 37, 433-435, 1974.

• 10) Leibo, S.P., Mazur, P. and Jackowski, S.C. : Factors affecting survival of mouse embryos during freezing and thawing. Exp. Cell Res., 89, 79-88, 1974.
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• 11) 宮本 元, 石橋武彦 : 液体窒素(-196°C)に凍結されたマウスの8細胞卵および桑実胚の生存性に影響をおよぼす要因. 日畜会報 47, 23-28, 1976.

• 12) Miyamoto, H., Katsuura, G. and Ishibashi, T. : Strain differences in survival of frozen-thawed mouse embryos. Jpn. J. Zootech. Sci., 48, 634-640, 1977.

• 13) Whittingham, D. G. : Fertilization in vitro and development to term of unfertilized mouse oocytes previously stored at-196°C. J. Reprod. Fert., 49, 89-94, 1977.

• 14) Maurer, R.R., Bank, H.and Staples, R.E. : Pre-and postnatal development of mouse embryos after storage for different periods at cryogenic temperatures. Biol. Reprod., 16, 139-146, 1977.
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• 15) Whittingham, D.G., Lyon, M.F. and Glenister, P. H. : Long-term storage of mouse embryos at-196° C : the effect of background radiation. Genet. Res., Camb., 29, 171-181, 1977.

• 16) 内海恭三, 湯原正高 : ラット受精卵の凍結保存に関する研究 : とくにドライアイスアルコールによる凍結保存について. 岡山大農学報 44, 24-27, 1974.

• 17) Whittingham, D.G. : Survival of rat embryos after freezing and thawing. J. Reprod. Fert., 43, 575-578, 1975.

• 18) Bank, H. and Maurer, R.R. : Survival of frozen rabbit embryos. Exp. Cell Res., 89, 188-196, 1974.
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• 19) Maurer, R.R. and Haseman, J. K. : Freezing morula stage rabbit embryos. Biol. Reprod., 14, 256-263, 1976.
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• 20) Ogawa, S. and Tomoda, S. : Survival of 16-celled and morula stage rabbit embryos frozen to -196°C. Exp. Anim., 25, 273-282, 1976.

• 21) Whittingham, D.G. and Adams, C.E. : Low temperature preservation of rabbit embryos. J. Report., 47, 269-274, 1976.

• 22) Tsunoda, Y. and Sugie, T. : Survival of rabbit eggs preserved in plastic straws in liquid nitrogen. J. Reprd. Fert., 49, 173-174, 1977.

• 23) Tsunoda, Y. and Sugie, T. : Effect of the freezing medium on the survival of rabbit eggs after deep freezing. J. Reprod. Fert., 50, 123-124, 1977.

• 24) Wilmut, I. and Rowson, L. E.A. : Experiments on the low-temperature preservation of cow embryos. Vet. Res., 92, 686-690, 1973.

• 25) Bilton, R.J. and Moore, N.W. : Successful transport of frozen cattle embryos from New Zealand to Australia. J. Reprod. Fert., 50, 363-364, 1977.

• 26) 杉江 佶, 角田幸生, 相馬 正 : 牛の凍結保存卵移植実験. 家畜繁殖誌 25, 203-205, 1979.

• 27) Willadsen, S.M., Polge, C., Rowson, L.E.A. and Moor, R.M. : Deep freezing of sheep embryos. J. Reprod. Fert., 46, 151-154, 1976.

• 28) Willadsen, S.M. : The viability of early cleavage stages containing half the normal number of blastomeres in the sheep. J. Reprod. Fert., 59, 357-362, 1980.

• 29) Bilton, R.J. and Moore, N.W. : In vitro culture, storage and transfer of goat embryos. Aust. J. Biol. Sci., 29, 125-129, 1976.
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• 30) 尾川昭三 : ラット, マウスの人工授精および哺乳動物胚の凍結保存について. 実験動物 27, 110-122, 1978.

• 31) 横山峯介, 豊田 裕 : 哺乳動物卵の体外受精ならびに凍結保存と疾患モデル動物. 実験動物 29, 293-296, 1980.

P.51 掲載の参考文献

• 1) 安東洪次, 田嶋嘉雄編 : 医学研究動物実験法. 朝倉書店, 1956.

• 2) 田嶋嘉雄編 : 実験動物学総論. 朝倉書店, 1972.

• 3) 藤原公策・他編 : 実験小動物の感染病. ソフトサイエンス社, 1976.

• 4) 田嶋嘉雄, 前島一淑, 江崎孝三郎, 藤原公策, 沢崎坦 : 実験動物学概論. 朝倉書店, 1979.

P.61 掲載の参考文献

• 1) L.C. Anderson et al. : Rat-bite fever in animal research laboratory personnel. Lab. Anim. Sci. 33 : 292-294, 1983.

• 2) 本庄重男 : 輸入サルの現状と問題点. 公衆衛生 44, 433-438, 1980.

• 3) W.T. Hubbert et al. (ed.) : Diseases Transmitted from Animals to Man. 6th. edit., Charles C. Thomas, Illinois, U. S. A. 1975.

• 4) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section A Vol. I, CRC Press, Florida, U.S.A. 1979.

• 5) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section A Vol. II, CRC Press, Florida, U.S.A. 1980.

• 6) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section B Vol. I, CRC Press, Florida, U.S.A. 1981.

• 7) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section B Vol. II, CRC Press, Florida, U.S.A. 1981.

• 8) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section C Vol. I, CRC Press, Florida, U.S.A. 1982.

• 9) J. H. Steele (ed.) : CRC Handbook Series in Zoonoses, Section C Vol. II, CRC Press, Florida, U.S.A. 1982.

• 10) 田嶋嘉雄・他 : 実験動物学概論. 朝倉書店, 東京, 1979.

• 11) 山内一也 : 医学生物学研究用の霊長類におけるウィルス汚染の問題. 実験動物 24, 1-12, 1975.

• 12) 吉田幸雄 : ヒトの Pneumocystis症. 実験動物 29, 269-275, 1980.

P.76 掲載の参考文献

• 1) 北野政次 : 流行性出血熱・最新ウイルス・リケッチア学 (1) (田宮猛雄論) 医歯薬出版 (東京) pp.451-427, 1957.

• 2) Smorodintsev, A.A. et al : Haemorrhagic nephroso-nephritis. Pergamon Press, London, pp.124, 1959.

• 3) Lee H. W. : Korean hemorrhagic fever. Evola Virus Hemorrhagic Fever. S. R Pattyn ed. Elsevier/North-Holland, pp.331-343, 1978.

• 4) 藤野恒三郎・他 : 流行性出血熱は日本にもある. (臨床細菌血清学談話会記録). 日本臨牀 20, 163-190, 1962.

• 5) 笠原四郎・他 : 流行性出血熱の病原体の決定. 日本病理学会誌, 34, 3-5, 1944.

• 6) Lee, H. W. et at : Isolation of the etiologic agent of Korean hemorrhagic fever. J. Infect. Dis., 137, 298-308, 1978.
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• 7) Information Exchange Subcommittee, American Committee on Arthropod-Borne Viruses, N. Karabatsos. (ed) Box 2087, Ft. Collins, CO 80522., 1981.

• 8) White, J. D. et al : Hantaan virus, aetiolgical agent of Korean haemorrhagic fever, has Bunyaviridae-like morphology. Lancet (April) 3, 768-771, 1982.

• 9) Kitamura, T. et al. : Isolation of virus causing hemorrhagic fever with renal syndrome (HFRS) through a cell culture system. Japan. J. Med. Sci. Biol., 36, 17-25, 1983.

• 10) 山之内孝尚・他 : 流行性出血熱 (腎症候性出血熱) 汚染実験ラットにおける感染伝播様式について第18回日本実験動物学会, (神戸8月, 1983発表).

• 11) 山西弘一・他 : ラット腫瘍組織より腎症候性出血熱(HFRS)ウイルスの分離. 第31回日本ウイルス学会総会, (大阪10月, 1983発表) .

• 12) 森本靖彦 : 流行性出血熱. 図説臨床内科講座(山村雄一監修) 第9巻, メジカルビュー社, pp.101-105, 1981.

• 13) 流行性出血熱(韓国型出血熱)診断の手引. 人獣共通感染症の検査体制に関する打合会(座長山村雄一)編 1981.

• 14) Tai, T., et al. : Epidemiologic and clinical studies of epidemic hemorrhagic fever. Chienese Medical J., 94, 143-148, 1981.

• 15) Lee, H. W. and Lee, P. W. : Korean hemorrhagic fever, I. Demonstration of causative antigen and antibodies. Korean J. Intern, Med., 19, 371-383, 1976.

• 16) 北野政次 : 流行性出血熱の感染経路発見の経緯と最近の世界的趨勢. 日本医事新報 2930, 6163, 1980.

• 17) Lee, H. W. et al. : Intraspecific transmission of Hantaan virus, etiologc agent of Korean hemorrhagic fever, in the rodent. Apodemus agrarius. Am. J. Trop. Med. Hyg., 30, 1106-1112, 1981.

• 18) Lee, H. W. et al. : Epidemiologic study of localized outbreak of Korean hemorrhagic fever in Kyungido Tongduchun, Songnaeri. Korean. J Virol., 9, 1-6, 1979.

• 19) Lee, H. W. et al. : Observations of natural and laboratory infection of rodents with the etiologic agent of Korean hemorrhagic fever. Am. J. Trop. Med. Hyg. . 30, 477-482, 1981.
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• 20) Lee, H. W. et al. : lsolation of Hantaan virus, the etiologic agent of korean hemorrhagic fever, from wild rats. J. Infect. Dis., 146, 638-634, 1982.

• 21) Tsai, T. K. et al : Preliminary evidence that Hantaan or a closely related virus is enzootic in domestic rodents. New England J. Med., 307, 623-624, 1982.

• 22) Leduc, J. W. et al : Preliminary evidence that Hantaan or a closely related virus is enzootic in domestic rodents. New England J. Med., 307, 624, 1982.

• 23) Lee, P. W. et al : Preliminary evidence that Hantaan or a closely related virus is enzootic in domestic rodents. New England J. Med., 307, 625, 1982.

• 24) Lee, H.W. et al : Isolational of Hantaan virus, the etiologic agent of hemorhagic fever with renal syndrome from wild urban rats in Japan.

• 25) Morita, C. et al : Detection of antibody against hemorrhagic fever with renal syndrome (HFRS) virus in sera of house rats captured in port areas of Japan. Jpn J. Med. Sci. Biol., 36, 55-57, 1983.
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• 26) 田村俊秀・他 : 清水港湾地区で捕獲された野鼠のHantaan virus抗体および抗原の保有状況. 第57回日本感染症学会 (大阪, 4月, 1983発表).

• 27) Tsai, T. F. et at : Intracerebral inoculation of suckling mice with Hantaan virus. Lancet (Aug), 28, 503-504, 1982.

• 28) 流行性出血熱(韓国型出血熱)の予防について. 「動物実験における人獣共通感染症, 特に流行性出血熱の現状調査とその防止対策の研究」班 (研究代表者, 川俣順一) 編, 1979.

• 29) 流行性出血熱(韓国型出血熱)予防指針 人獣共通感染症の検査体制に関する打合会(座長山村雄一)編, 1981.

• 30) 山之内孝尚 : 腎症候性出血熱. 代謝 20, 521-531, 1983.

• 31) Gajdusek, D. C. et al : Bibliography of hemorrhagic fever with renal syndrome (muroid virus nephrop-athy) published by National Institutes of Health, U. S. A., 1982.

P.104 掲載の参考文献

• 1) Umenai, T., H. W. Lee, P. W. Saito, T. Toyoda, M. Hongo, K. Yoshinaga, T. Nobunaga, T. Horiuchi, N. Ishida : Korean hemorrhagic fever in staff in an animal laboratory. Lancet i, 1314-1316, 1979.

• 2) 西岡新吾・他 : 和歌山医科大学内に発生した流行性出血熱-特に7例の臨床像を中心に-. 感染症学雑誌 5, 410-428, 1981.

• 3) Myhrman, G. : Nephropathia epidemica : a new infectious disease in Northern Scandinavia. Acta. Med. Scand. 140, 52-56, 1951.
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• 4) Smorodintsev, A. A. et al : Haemorrhagic nephroso-nephritis. Pergamon Press, London, p124, 1959,

• 5) 陸軍省医務局 : 「叢報」流行性出血熱に就て. 陸軍軍医団雑誌 346, 361-371, 1942.

• 6) Sheedy, J. A., et al : Symposium on Epidemic Hemorrhagic Fever. Am. J. Med., 16, 617-709, 1954.

• 7) Lee, H. W., Lee, P. W. and Johnson, K. M : Isolation of the etiologic agent of Korean hemorrhagic fever. J. Infect. Dis. 137, 298-308, 1978.
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• 8) 川俣順一 : 動物実験における人獣共通感染症, 特に流行性出血熱の現状調査とそれらの防止対策の研究. 昭和57年科研報告書 1983, 3月.

• 9) 田村雅太 : 流行性出血熱 特に大阪市に流行する軽症例について. 臨床科学 1, 905-909, 1965.

• 10) 田村雅太 : 流行性出血熱に関する研究. 日本伝染病学会雑誌 40, 286-294, 1966.

• 11) 環境調節委員会・小動物班 : 実験動物飼育施設の建築および設計計画の基準案. 実験動物 15, 17-41, 1966.

• 12) Martini, G.A. and Siegert, R. ed. : Marburg virus disease. Springer Verlag, Berlin, 1971.

• 13) Frame, J.E. et al : Lassa fever, a new virus diseases in West Africa. I. Clinical description and pathological findings. Am. J. Trop. Med. Hyg., 19, 670-676, 1979.

• 14) 国立予防衛生研究所 : 国立予防衛生研究所病原体等安全管理規程. 1980年4月.

• 15) 大谷 明・他 (編) バイオハザード対策ハンドブック : 近代出版社 1981年1月.

• 16) Lind, A. : Danger of TB infection to personnel in pathological laboratories. Transact. NAPT Common-wealth Chest Cont, 1958.

• 17) 山之内孝尚・他 : 流行性出血熱感染ラットにおける感染伝播様式について. 第18回日本実験動物学会発表, 神戸1983, 8月.

• 18) 山西弘一・他 : ラット腫瘍組織より腎症候性出血熱(HFRS)ウィルスの分離. 第31回日本ウイルス学会総会発表, 大阪, 1983, 10月.

• 19) Yamanishi, K., et al : Isolation of hemorrhagic fever with renal syndrome (HFRS) virus from a tumor specimen in a rat. Biken J. 25, 155-160, 1983.

• 20) Reyniers, J.A., et al : Multiple tumors in female germfree inbred mice exposed to bedding treated with exthylene oxide. J. Nat. Cancer Inst., 32 : 1045-1058, 1964.
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