書籍詳細

III期病期診断上の問題点

P.8 掲載の参考文献

• 1) Genereux, G. P. and Howie, J. L. : Normal Mediastinal Lymph Node Size and Number. AJR. 142 : 1095-1100, 1984.
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• 2) Glazer, G. M., Gross, B. H., Quint. L. E. et al : Normal Mediastinal Lymph Nodes : AJR. 144 : 261-265, 1985.
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• 3) Quint, L. E., Glazer, G. M., Orringer, M. B. et al : Mediastinal Lymph Node Detection and Sizing at CT and Autopsy. AJR.147 : 469-472, 1986.
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• 4) 鈴木正行 : 原発性肺癌の縦隔リンパ節転移のCT診断に関する基礎的並びに臨床的検討. 日医放会誌 48 : 308-327, 1988.

• 5) Kiyono, K., Sone, S., Sakai. F. et al : The Number and Size of Normal Mediastinal Lymph Nodes. AJR.150 : 771-776, 1988.
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• 6) Libshitz, H.I. and Mckenna, R. J. : Mediastinal Lymph Node Size in Lung Cancer. AJR. 143 : 715-718, 1984.
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• 7) Glazer, G. M., Orringer, M. B., Gross, B. H. et al : The Mediastinum in Non-Small Cell Lung Cancer. AJR. 142 : 1101-1105, 1984.
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• 8) Daly, B. D., Faling, L. J., Pugatch, R. D. et al : Computed Tomography. JTCS. 88 : 486-494, 1984.

• 9) Martini, N., Heelan, R., Wescott, J. et al : Comparative merits of conventional, computed tomographic, and magnetic resonance imaging in assessing mediastinal involvement in surgically comfirmed lung carcinoma. JTCS 90 : 639-648, 1985.

• 10) Mckenna, R. J., Libshitz. H.I. Mountain, C. E. et al : Roentgenographic Evaluation of Mediastinal Nodes for Preoperative Assessment in Lung Cancer. Chest 88 : 206-210, 1985.
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• 11) Platt, J. F., Glazer, G. M., Gross, B. H. et al : CT Evaluation of Mediastinal Lymph Nodes in Lung Cancer. AJR. 149 : 683-686, 1987.
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• 12) Daly, B. D. Faling, L. J., Bite, G. et al : Mediastinal Lymph node evaluation by computed tomography in Lung Cancer. JTCS. 94 : 664-672, 1987.

• 13) Patterson, G. A., Ginsberg, R. J., Poon, P. Y. et al : A prospective evaluation of magnetic resonance imaging, computed tomography, and mediastinoscopy in the preoperative assessment of mediastinal node status in bronchogenic carcinoma. JTCS. 94 : 679-684, 1987.

• 14) Whittlesey, D. : Prospective computed tomographic scanning in the staging of bronchogenic cancer : JTCS. 95 : 876-882, 1988.

• 15) Staples, C. A., Mtiler, N. L, Miller, R. R. et al : Mediastinal Nodes in Bronchogenic Carcinoma : Comparison between CT and Mediastinoscopy. Rad. 167 : 367-372, 1988.

• 16) 森 清志, 江口研二, 森山紀之・他・肺癌の術前評価における胸部CTと胸部X線診断. 肺癌 26 : 381-390, 1986.

P.15 掲載の参考文献

• 1) Akovbiantz, A. : Aktuelle Probleme in Chirurugie und Orthopadie. Die Mediastinoskopie. Verlag Hans Huber Bern Stuttgart Wien 1977.

• 2) Pearson, F. G. : An evaluation of mediastinoscopy in the management of presumbly operable bronchial carcinoma. J. Thorac. Cardiovasc. Surg. 55 : 617-625, 1968.

• 3) Luke, W.P., Pearson, F. G, Cooper, J. D. et al : Prospective evaluation of mediastinoscopy for assesment of carcinoma of the Iung. J. Thorac. Cardiovasc. Surg. 91 : 53-56, 1986.

• 4) Jolly, P. C, Li W, Anderson, R. P. et al : Anterior and cervical mediastinoscopy for determining operability and predicting resectability in lung cancer. J. Thorac. Cardiovasc. Surg. 79 : 366-371, 1980.
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• 5) Reynders, H. : Mediastinoscopy in bronchogenic cancer. Dis. Chest 45 : 606-611, 1964.
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• 6) Doctor, A. H. : Mediastinoscopy : acritical evaluation of 220 cases. Ann. Surg. 174 : 965-968, 1971.

• 7) MaaBen, W. : Ergebnisse und bedeutung der mediastinoskopie und anderer thoraxbioptischer verfahren, Springer-Verlag Berlin Heidelberg New York, 1967.

• 8) Fosburg, R. G., O'Sullivan, M. J., Oury, J. H. et al : Positive mediastinoscopy. Ann. Thorac. Surg. 18 : 346-356, 1974.
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• 9) 人見滋樹, 畠中陸郎, 寺松 孝・他 : 縦隔洞の内視鏡的診断-縦隔鏡検査-. 臨床科学 9 : 409-417, 1973.

• 10) 平田正信, 荒井他嘉司, 田島 洋・他 : 縦隔鏡検査からみた肺癌の手術適応. 日胸 8 : 634-639, 1983.

• 11) 松原義人, 船津武志, 池田貞雄・他 : 肺癌外科治療における縦隔鏡検査の意義. 日外会誌 88(臨) : 142, 1988.

• 12) Goldberg, E. M., Glicksman, A. S., Nickson, J. J. et al : Mediastinoscopy for assessing mediastinal spread in clinical staging of carcinoma of the lung. Cancer 25 : 347-353, 1970.
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• 13) Goldstraw, P., Kurzer, M. and Edwards, D. : Preoperative staging of lung cancer : accuracy of computed tomography versus mediastinoscopy. Thorax 38 : 10-15, 1983.
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• 14) Schoolmeesters, J. E. P. V. : Experience with the artronix torso-cat-scanner in the examination of the thorax, particularly the mediastinum : Comparison with mediastinoscopy and operation. Diagnostic Imaging 52 : 93-100, 1983.

• 15) Van Shill, P. E. Y., Van Hee, R. H. G. G. and Schoofs, E. L. G. : The value of mediastinoscopy in preoperative staging of bronchogenic carcinoma. J. Thorac. Cardiovasc Surg. 97 : 240-244, 1989.

• 16) Pearson, F. G., DeLarue, N. C., Cooper, J. D. et al : Significance of positive superior mediastinal nodes identified at mediastinoscopy in patients with resectable cancer of the lung. J. Thorac. Cardiovasc. Surg. 83 : 1-11, 1982.
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P.25 掲載の参考文献

• 1) Musset, D., Grenier. P., Carette, M. F. et al : Primary Lung Cancer Staging : Prospective Comparative Study of MR Imaging with CT. Radiology 160 : 607-611, 1986.
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• 2) Abrams, H. L. (Panel and Conference Chairperson) et al : Magnetic Resonance Imaging. National Institutes of Health Consensus Development Conference Statement. 6(14) : 11-24, 1987.

• 3) Ross, J. S., O'Dollovan, P. B., Novoa, R. et al : Magnetic resonance of the chest : Initial experience with imaging and in vivo T1 and T2 calculations. Radiology 152 : 95-101, 1984.

• 4) Muller, N. L., Gamsu, G., Webb, W. R. : Pulmonary nodules : Detection using magnetic resonance and computed tomography. Radiology 155 : 687-690, 1985.
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• 5) 河野通雄, 佐古正雄, 足立秀治・他 : 肺癌病期分類と治療効果判定並びに再発診断におけるMRIの応用. 日本医放会誌 49 : 831-840, 1989.

• 6) Webb, W.R., Jensen, B. G., Sollitto, R. et al : Bronchogenic carcinoma；Staging with MR compared with staging with CT and surgery. Radiology 156 : 117-124, 1985.
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• 7) Kameda, K., Adachi, S., Kono, M. : Detection of T factor in hmg cancer using magnetic resonance imaging and computed tomography. J. Thorac. Imag. 3 : 73-80, 1988.

• 8) Claussen, C., Laniado, M., Schorner, W. et al : Gadolinium-DTPA in MR imaging of glioblastomas and intracranial metastases. Am. J. Neuroradiol. 6 : 669-674, 1985.
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• 9) 鈴木正行, 高島 力 : 肺癌のリンパ節転移. 臨放 31 : 1285-1299, 1986.

• 10) Kiyono, K., Sone, S., Sakai, F. et al : The Number and Size of Normal Mediastinal Lymph Nodes : Apostmortem Study. AJR. 150 : 771-776, 1988.
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• 11) Glazer, G. M., Orringer, M. B., Chenevert, T. L. et al : Mediastinal Lymph Nodes : Relaxation Time/Pathologic Correlation and Implications in Staging of Lung Cancer with MR Imaging. Radiology 168 : 429-431, 1988.
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• 12) 佐古正雄, 清水雅史, 河野通雄 : 7. M因子の解析-肺癌の腹部臓器転移の画像診断. -とくにCT, 超音波検査の現況と課題. 肺癌の画像診断. 99-107, 日本肺癌学会第2回ワークショップ, 1987.

• 13) Chezmar, J. L., Robbins, S. M., Nelson, R. C., et al : Adrenal Masses : Characterization with T1-weighted MR Imaging. Radiology 166 : 357-359, 1988.
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• 14) Zeitler, E., Kaiser. W., Feyer, E. et al : Magnetic resonance imaging, with and without Gd-DTPA, of bronchial carcinoma, contrast agents in magnetic resonance imaging. Proceedings of an international Workshop, 147-149, 1986. San Diego, Calif.

III期肺癌の予後因子の解析

P.34 掲載の参考文献

• 1) Kawahara, M., Furuse, K., Tsuruta, S. et al : A randomized study of CDDP versus CDDP+ vindesine in non-small cell carcinoma of the lung, Proc. of 14th international congress of chemotherapy, Kyoto, 1985.

• 2) 松井 薫, 福岡正博, 根来俊一・他 : 進行非小細胞肺癌に対する無作為化比較試験 : CDDP+VDS (CV) vs CDDP+VDS+MMC (CVM) vs CDDP+Etoposide→VDS+MMC(CE→VM). 日胸疾会誌 27 : 291, 1989.

• 3) Mountain, C. F. : A new international staging system for lung cancer. Chest. 89 : 225s-233s, 1986.
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• 4) Zubrod, C. G., Schneiderman, M., Frei, E. et al : Appraisal of methods for the study of chemotherapy of cancer in man : Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide. J. Chron. Dis. 11 : 7-33, 1960.

• 5) 原発性ならびに転移性肺腫瘍の肺所見に対する化学療法および放射線療法の腫瘍効果判定基準 : 肺癌取り扱い規約(改訂第3版) pp.135-145 金原出版, 東京, 1987.

• 6) Kaplan, E. L. and Meier, P. : Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53 : 457-481, 1958.

• 7) Gehan, E. A. : A generalized wilcoxon test for comparing arbitrarily singly censored samples. Biometrika, 52 : 203-223, 1965.
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• 8) Cox, D. R. : Regression models and life-tables. J Royal Stat. Soc. Series B, 34 : 187-220, 1972.

• 9) Stanley, K. E. : Prognostic factors for survival in patients with inoperable lung cancer. J. NCI. 65 : 25-32, 1980.

• 10) O'Connell, J. P., Kris, M. G., Gralla, R. J. et al : Frequency and prognostic importance of pretreatment clinical characteristics in patients with advanced non-small-cell lung cancer treated with combination chemotherapy. J. Clin. Oncol. 4 : 1604-1614, 1986.
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• 11) 浦田淳夫 : 切除不能肺癌の予後因子.癌と化学療法 15 : 2035-2042, 1988.
  Medical*Online

• 12) Lee, J. S., Ro, J. Y., Sahin, A. et al : Expression of epidermal growth factor receptor (EGFR) : A favorable prognostic factor for surgically resected non-small cell lung cancer (NSCLC). ASCO 8 : 226, 1989.

• 13) Volm, M., Harn, E. W., Mattern, J. et al : Five-year follow-up study of independent clinical and flow cytometric prognostic factors for the survival of patients with non-small cell lung carcinoma. Cancer Research 48 : 2923-2928, 1988.

P.42 掲載の参考文献

• 1) Mountain, C. F. : A new international staging system for lung cancer. Chest(Suppl) 89 : 225-233, 1986.

• 2) Spiegelman, D., Maurer, L. H., Ware, J. H. et al : Prognostic factors in small-cell carcinoma of the lung : An analysis of 1,521 patients. J. Clin. Oncol. 17 : 344-354, 1989,

• 3) 浦田淳夫 : 切除不能肺癌の予後因子. 癌と化学療法 17 : 2035-2042, 1988.

• 4) 富永祐民 : 治療効果判定のための実用統計学. 蟹書房, 東京, 1987.

• 5) 原 信之, 本広 昭, 一瀬幸人・他 : 肺癌外科治療の再評価-術後の補助療法は手術成績の向上につながったか. 日本胸部臨床 48 : 444-450, 1989.

• 6) Piehler, J. M., Pairolero, P. C. and Weilard, L. H. : Bronchogenic carcinoma with chest wall invasion : Factors affecting survival following en bloc resection. Ann. Thorac. Surg. 34 : 684-691, 1982.

• 7) Jamieson, M. P. G., Walbaum, P. R. and McCormack, R J.M. : Surgical managent of bronchial carcinoma invading the chest wall. Thorax 34 : 612, 1979.

• 8) Pearson, F. G., Delarme, N. C. and Ilves, R. : Significance of positive superior mediastinal nodes identified at mediastinoscopy in patients with resectable cancer of the lung. J. Thorac. Cardiovasc. Surg. 83 : 1-11, 1982.

• 9) Naruke, T., Goya, T. and Tsuchiya, R. : The importance of surgery to non-small cell carcinoma of lung with mediastinal lymphnode metastasis. Ann. Thorac. Surg. 46 : 603-610, 1988.

• 10) Martini, N., Flehinger, B. J. and Zaman, H. B. : Results of resectionin non-oat cell carcinoma of the lung with mediastinal lymph node metastases. Ann. Surg. 198 : 386-397, 1983.

• 11) Martini, N., Flehinger, B. J. and Bains, M. S. : Alternate Approaches to the management of mediastinal adenopathy. International Trends In General Thoracic Surgery Volume 1. 108-120, W B Saunders Company, 1985.

• 12) Holmes, E. C. and Gail, M. : Surgical adjuvant therapy for stage II and III adenocarcinoma and large-cell undifferentiated carcinoma. J. Clin. Oncol. 4 : 710-715, 1986.
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• 13) Kirsh, M. V. and Sloan, H. : Mediastinal metastases in bronchogenic carcinoma : Influence of postoperative irradiation, cell type and location. Ann. Thorac. Surg. 33 : 459-463, 1982.

• 14) The Lung Cancer Study Group : Effects of postoperative mediastinal radiation on completely resected stage II and stage III epidermoid cancer of the lung. New Engl. J. Med. 315 : 1377, 1986.

• 15) Shields, T. W., Higgins, G. A., Humphrey. et al : Prolonged intermittent adjuvant chemotherapy with CCNU and hydroxyurea after resection of carcinoma of the lung. Cancer 50 : 1713-1721, 1982.
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P.51 掲載の参考文献

• 1) Carmack Holmes, E. (Lung Cancer Study Groups) : A randomized comparison of the effects of adjuvant therapy on resected Stage II andM Non-small cell carcinoma of the lung. Ann. Surg. 202(3) : 335-341, 1985.

• 2) 森 隆・他 : 肺癌患者の新しいパラメーター : 組み合わせ血液検査値による術後93例の予後予測性. 日胸臨 40(4) : 327-333, 1981.

• 3) 森 隆, 井内敬二, 沢村献児・他 : 予後から見た肺癌術後合併療法の評価-外科療法をどこまで補助できるか-. 日胸外誌 31(5) : 237-239, 1983.

• 4) 土井 修・他 : 肺扁平上皮癌, 腺癌の術後再発様式. 肺癌 25(3) : 321-327, 1985.

• 5) 森 隆, 沢村献児, 井内敬二・他 : 肺癌の組織型別, 病期別, 手術根治性別にみた術後成績 : 予後と手術適応決定のために. 日外会誌 86(臨時増刊号) : 165, 1985.

• 6) 森 隆, 沢村献児, 土井 修・他 : Adjuvant therapy-randomized controlled study-. 肺癌 28 (5) : 599, 1988.

現在までの外科治療の成績

P.63 掲載の参考文献

• 1) 小池輝明, 広野達彦, 山口 明・他 : 肺癌切除対象例に対する斜角筋前リンパ節生検の意義. 日胸外会誌 36 : 870-873, 1988.

• 2) 広野達彦, 小池輝明, 山口 明・他 : 胸骨正中切開による左肺癌の縦隔リンパ節郭清術. 臨床胸部外科 1 : 312-313, 1981.

• 3) 広野達彦, 坂下 勲, 佐藤良智・他 : 胸骨正中切開による左肺癌の縦隔リンパ節郭清術. 日胸外会誌 29 : 1536-1542, 1981.

• 4) 竹内慶治, 勝本慶一郎, 新堀 立・他 : 肺癌に対する左房合併切除術の検討. 日胸外会誌 31 : 1448-1454, 1983.

• 5) 中川 健, 松原敏樹, 木下 巌・他 : 肺癌に対する隣接臓器合併切除例の検討. 臨外 42 : 31-40, 1987.

• 6) 土屋了介 : 大血管侵襲を伴う肺癌に対する拡大手術の意義と限界. 肺癌 27 : 454, 1987.

• 7) 呉屋朝幸, 近藤晴彦, 土屋了介・他 : 肺癌 T4, 外科治療例の検討. 肺癌 28 : 601, 1988.

• 8) 西山祥行, 天願 勇, 松山智治・他 : 進行肺癌外科治療の限界-拡大合併切除よりみた限界-. 日外会誌 83 : 979-982, 1982.

• 9) 大岩孝司, 斉藤博明 : 癌性胸膜炎を伴った原発性肺癌に対する胸膜肺全剔術の臨床的検討. 肺癌 26 : 259-265, 1986.

• 10) 酒井忠昭, 池田高明, 菊地功次・他 : 原発性肺癌による癌性胸膜炎に対する胸膜・肺全剔術の適応. 肺癌 26 : 637-641, 1986.

• 11) 小池輝明, 広野達彦, 滝沢恒世・他 : 癌性胸膜炎合併肺癌の外科治療. 日胸 47 : 13-18, 1988.

• 12) 羽田圓城, 早川和志, 宮元秀昭・他 : 左肺癌手術症例の対側縦隔リンパ節転移頻度と予後. 日胸外会誌 48 : 275-281, 1989.

非観血的治療の成績

P.69 掲載の参考文献

• 1) Tailor, S. G., Trybula, M., Kittle, C. F. et al : Simultaneous Cisplatin Fluolouracil infusion and radiation followed by surgical resection in regionally localized Stage III non-small cell lung cancer. Ann. Thrac. Surg. 43(1) : 87-91, 1987.

• 2) Wils, J., Utama, I. and Smeets, J. : Chemotherapy consisting of Epirubicin, Cisplatin, and Etoposide followed by irradiation in Stage III non-small cell lung cancer and chemotherapy alone in Stage IV non-small cell lung cancer. Oncology 45 : 413-416, 1988.
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• 3) Wils, J. A., Utama, I., Verschueren, T. A. et al : Phase ll randomized trial of radiotherapy alone vs the sequential use of chemotherapy and radiotherapy in Stage III non-small cell Iung cancer. Phase II trial of chemotherapy alone in Stage IV non-small cell lung cancer. Eur. J. Cancer Clin. Oncol. 20(7) : 911-914, 1984.

• 4) Frytak, S., Sawamura, K., Pairolero, P. C. et al : Treatment of "Limited" Stage III non-small cell carcinoma of the lung. Cancer Investigation 6(2) : 193-207, 1988.
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• 5) 高橋正治, 阿部光幸 : 肺癌治療における放射線療法の役割. 癌と化学療法12(1) : 61-69, 1985.

• 6) Einhorn, L. H. : Neoadjuvant therapy of Stage III non-small cell lung cancer. Ann. Thrac. Surg. 46(3) : 362-365, 1988.

• 7) Martini, N. and McCormac, P. : Therapy of Stage III (Nonmetastatic disease). Seminars in Oncology 10(4) : 95-110, 1983.

• 8) Trakhtenberg, A. K., Kisereva, E. S., Schweiger, O. et al : Preoperative radiotherapy in the combined treatment of lung cancer patients. Neoplasma 35(4) : 459-465, 1988.

• 9) The lung cancer study group : Effect of postoperative mediastinal radiation on completely resected Stage III epidermoid cancer of the lung. New Engl. Med. 315(22) : 1377-1381, 1986.

• 10) Montebello, J. F. : Preoperative and Postoperative radiation therapy in non-small-cell lung cancer. Indiana Medicine 81(2) : 123-126, 1988.
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• 11) 木村 誠, 早川和重, 新部英男・他 : 原発性肺癌の放射線治療成績向上に関する検討. 日癌治 18 (7) : 1821-1830, 1983.

• 12) 新部英男, 中島信明, 木村 誠・他 : 肺癌の診療, 放射線療法.内科 52(4) : 681-684, 1983.

• 13) 新部英男, 中島信明, 早川和重 : 肺癌の診療-最近の進歩-, 放射線療法. 診断と治療 75(4) : 984-988, 1987.

• 14) 中島信明, 早川和重, 新部英男・他 : 肺癌放射線治療における縦隔リンパ節転移部位別の予後に関する検討. 日本医放会誌 46(9) : 1125-1129, 1986.

• 15) 中山優子, 早川和重, 新部英男・他 : 無気肺型肺癌の放射線治療. 肺癌 28(2) : 189-194, 1988.

• 16) 中島信明, 早川和重, 新部英男・他 : 肺類表皮癌の放射線治療による長期生存例の予後解析. 放治システム研究 2 : 101-106, 1985.

• 17) 斉藤吉弘, 早川和重, 新部英男・他 : 原発性肺癌の放射線治療-腺癌への適応-. 肺癌 26(7) : 789-794, 1986.

• 18) 新部英男 : 放射線腫瘍学. 講談社, 東京, 1988

• 19) Oswit, B. and White, D. C, : Severe radiation injuries of the lung. Am. J. Roentg. 129 : 127-136, 1977.

• 20) Payne, D. G. : Non-small cell lung cancer : Schould unresectable Stage III patients routinely receive high-dose radiation therapy. J. Clin. Oncol. 6(3) : 552-558, 1988.

• 21) 前原康延, 早川和重, 新部英男・他 : 高齢者原発性肺癌の放射線治療についての検討. 肺癌 24(6) : 727-733, 1984.

• 22) 恒元 博 : 放医研における速中性子線治療. 癌の臨床 34(13) : 1833-1838, 1988.

• 23) 三橋紀夫, えの目一郎, 新部英男・他 : Misonidazoleの放射線増感作用に関する臨床評価. 日本医放会誌 44(7) : 956-965, 1984.

• 24) Onoyama, Y. : Clinical and pharmacological study of Misonidazole. Modification of Radio-sensitivity in Cancer Treatment, ed, by Sugahara, ACADEMIC PRESS, INC. Tokyo, pp.195-217, 1984.

• 25) Cox, J. D, and Bauer, M. : Therapeutic ratio and fractionation in cancer of the lung. Front. Raciat. Ther. Onc. 22 : 121-126, 1988.

• 26) Perez, C. A., Bauer, M. et al : Impact of tumor control on survival in carcinoma of the lung treated with irradiation. Int. J. Radiat. Oncol. Biol. Phys. 12 : 535-547, 1986.

P.77 掲載の参考文献

• 1) Rapp, E., Pater, J. L, Willan, A. et al : Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer-Report of a Canadian multicenter randomized trial. J. Clin. Oncol. 6 : 633-641, 1988.

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• 3) Gralla, R.J., Cox, J.D. and Perry, M.C. : Multi-modality therapy for stage III non-small cell lung cancer. In ASCO Educational Booklet, pp.17-31, 1989.

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Adjuvant therapyの試みと評価

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Neoadjuvant therapyの試み

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• 1) Perez, C. A., Bauer, S. et al : Impact of tumor control on survival in carcinoma of the lung treated with irradiation. Int. J. Rad. Oncol. Biot. Phys. 12 : 539-547, 1986.

• 2) Perez, C. A., F. Pajak. et al : Long-term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive ratiotherapy. Cancer 59 : 1874-1881, 1987.

• 3) 森田皓三 : 放射線療法と薬剤との併用療法. 癌の臨床 24 : 894-897, 1978.

• 4) 森田皓三 : 放射線治療を軸としたMulti-modal treatment. 癌と化学療法 7 : 1738-1745, 1980.

III期非小細胞の臨床試験とInformed consent

P.152 掲載の参考文献

• 1) Epstein, L. C. and Lasagna, L. : Obtaining informed consent. Arch. Intern. Med. 123 : 682-688, 1969.
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• 2) Labacqz, K. and Levine, R. J. : Respect for persons and informed consent to participate in research. Clin. Res. 25 : 101-107, 1977.

• 3) Novack, D. H., Plumer, R., Smith, R. L. et al : Changes in physicians' attitudes toward telling the cancer patient. JAMA. 241 : 897-900, 1979.
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• 4) 田沢公樹, 中島宏昭, 石原潤一・他 : わが国の肺癌化学療法における informed consent. 日本癌治療学会誌 21 : 2454-2459, 1986.

• 5) Penman, D. T., Holland, J. C, Bahna, G. F. et al : Informed consent for investigational chemotherapy : patients' and physicians' perceptions. J. Clin. Oncol. 2 : 849-855, 1984.
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• 6) Cassileth, B. R., Zupkis, R. V., Sutton-Smith, K. and March, V. : Inforlned consent- why are its goals imperfectly realized. New Engl. J. Med. 302 : 896-900, 1980.
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• 7) Lind, S. E., Good, M. D., Seidel, S. et al : Telling the diagnosis of cancer. J. Clin. Oncol. 7 : 583-589, 1989.

• 8) Holland, J. C. : Now we tell- but how tell. J. Clin. Oncol. 7 : 557-559, 1989.

• 9) Taylar, K. M. and Kelner, M. : Informed consent : the physicians' perspective. Soc. Sci. Med. 24 : 135-143, 1987.

• 10) Rodenhuis, S., Van Den Heuvel, W. J. A., Annyas, A. A. et al : Patient motivation and informed consent in a phase I study of an anticancer agents. Eur. J. Cancer Clin. Oncol. 20 : 457-462, 1984.

• 11) President's commission for the study of ethical problems in medicine and biomedical research. Making health care decision. Washington : Government Printing Office, 1983.

P.159 掲載の参考文献

• 1) 大西明弘, 石崎高志 : 薬物治験に関する倫理的諸問題. 医療・医学研究における倫理の諸問題, 岡本 直正他編集, 東京医学社, 東京, pp.107-120, 1988.

• 2) 砂原茂一(訳) : ヘルシンキ宣言. 臨床薬理 6 : 375-378, 1975.

• 3) 田沢公樹, 中島宏昭, 石原潤一・他 : わが国の肺癌化学療法における informed consent-全国アンケート調査-. 日癌治 21 : 2454-2459, 1986.

• 4) Chanbner, B. A., Wittes, R., Hoth, D. et al : Investigational trials of anticancer drugs : Establishing safeguards for experimentation. Public Health Report 99 : 355-360, 1984.

• 5) 馬場一雄 : 医療行為の倫理. 医療・医学研究における倫理の諸問題. 岡本直正他編集. 東京医学社, 東京, pp.62-69, 1988.

• 6) 昭和大学医学部医の倫理委員会規程, 1987.

• 7) 福田一彦, 小林重雄(訳) : 日本版SDS. 三京房, 1974.