書籍詳細

I. 肝類洞壁細胞の構造と機能

P.10 掲載の参考文献

• 1) von Kupffer C:Ueber Sternzellen der Leber. Briefliche Mittheilung an Prof. Waldeyer Arch Mikr Anat 12:353-358, 1876

• 2) 和気健二郎:星細胞発見のKupfferの原著. 解剖誌53:368-372, 1978

• 3) Wake K:Distribution of vitamin A in the liver. Proc. 5th Annual General Meeting of Japaneese Histochemical Association, 103-106, 1964

• 4) Wake K:"Sternzellen"in the liver:Perisinusoidal cells with special reference to storage of vitamin A. Am J Anat 132:429-462, 1971
  pubmed

• 5) Wake K, Motomatsu K, Senoo H, et al:Improved Kupffer:s gold chloride method for demonstrating the stellate cells storing retinol (vitamin A) in the liver and extrahepatic organs of vertebrates. Stain Technol 61:193-200, 1986
  pubmed

• 6) Rothe P:Ueber die Sternzellen der Leber. Inaug Diss. Munchen, 1882

• 7) Wake K:Cytochemistry of the lipid droplets containing vitamin A in the liver. Proc. 2nd Int. Symposium on Electron Microscopy and Cytochemistry. Drienerlo, The Netherlands. E. Wisse W, Th. Daems I, Molenaar, and P van Duijn, (eds.) North-Holland Publinshing Co., (Amsterdam), 1973

• 8) von Kupffer C:Ueber Sternzellen der Leber. Verh d Anat Ges 12 Vers in Kiel S, 80-86, 1898

• 9) von Kupffer C:Ueber die sogenannten Sternzellen der Stiugethierleber. Arch f Mikr Anat 54:254-288, 1899

• 10) Wake K:Perisinusoidal stellate cells (fat-storing cells;interstitial cell;lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cell in extrahepatic organs. Int Rev Cytol 66:303-353, 1980
  pubmed

• 11) Browicz T:Ueber intravascultire Zellen in den Blutcapillaren der Leberacini. Arch Mikr Anat 55:420-426, 1900

• 12) Zimmermann KW:Uber das Verhaltnis der"Kupfferschen Sternzellen"zum Endothel der Leberkapillaren beim Menschen. Z. Mikr Anat Forsch 14:528-548, 1928

• 13) Pfuhl W:Mollendorff's Handbuch der mikroskopischen Anatomie des Menschen. V/2 Bd. Verdauungsapprat. Die Leber, 1932

• 14) Wisse E:An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastruct Res 31:125-150, 1970
  pubmed

• 15) 伊東俊夫:人のクップェル星細胞と肝毛細管壁に見られる脂肪摂取細胞の研究. 解剖誌26:42, 1951

• 16) 鈴木 清:組織の鍍銀法, 実験治療. Nα310~320, 武田薬品工業, 大阪, 1958

• 17) Zimmermann KW:Der feinere Bau der Blutcapillaren Zfd ges Anat 68:29-109, 1923

• 18) Wake K:Liver perivascular cells revealed by goldand silver impregnation methods and electron microscopy. "Biopathology of the liver:A text-atlas of fine structure"ed by Motta, PM, 23-36, MTP Press Limited, Lancaster (in press)

• 19) Wisse E, van't Noordende JM, van der Meulen J, et al:The pit cell:Description of a new type of cell occurring in rat liver sinusoids and peripheral blood. Cell Tiss Res 173:423-435, 1976"

• 20) Kaneda K, Wake K:Distribution and morphological characteristics of the pit cells in the liver of the rat. Cell Tiss Res 233:485-505, 1983

• 21) Kaneda K, Dan C, Wake K:Pit cells as natural killer cells. Biomed Res 4:567-576, 1983

• 22) Dan C, Kaneda K, Wake K:Astriking increase in rod-cored vesicles in pit cells (natural killer cells) and augmentation of the liver associated natural killer activity by a streptococcal preparation (OK-432) . Biomed Res 6:347-351, 1985

• 23) 段千恵子, 金田研司, 和気健二郎:組織のLGLについて-Organ-associated NKcell-. Medical Immunology 11:219-223, 1986

P.20 掲載の参考文献

• 1) Wisse E:An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastruct Res 31:125-150, 1970
  pubmed

• 2) Porta EA, Gomez-Dumm CLA:Anew experimental approach in the study of chronic alcoholism. Lab Invest 18:352-364, 1968

• 3) 金岡彦治, 岡上 武, 澤 美彦, 他:慢性エタノール投与ラットにおける肝類洞内皮細胞小孔の定量的解析. アルコール代謝と肝, Vol.6. 東京, 東洋書店, 280-287, 1987

• 4) 金岡彦治, 岡上 武, 澤 美彦, 他:種々の灌流圧におけるラット肝類洞内皮細胞小孔の定量的解析. 肝蔵5:578-585, 1987

• 5) Wisse E, De Zanger RB, Jacob R:Lobular gradients in endothelial fenestrae and sinusoidal diameter favour centrolobular exchange processes:A scanning electron microscopy study. in Sinusoidal liver cells, Amsterdam, Elsevier, 61-67, 1982

• 6) 織田正也, 塚田信廣, 小松弘一, 他:肝類洞内皮細胞の超微形態と機能. 肝臓25:127-131, 1984

• 7) Horn T, Henriksen JH, Christoffersen P, et al:The sinusoidal liningcells in normal human liver. A scanning electron microscopic investigation. Liver 6:98-110, 1986

• 8) Brooks SEH, Haggis GH:Scanning electron microscopy of the rat liver. Lab Invest 29:60-64, 1973

• 9) Fraser R, Bowler LM, Day WA:Damage of liver sinusoidal endothelium by ethanol. Pathology l2:371-376, 1980

• 10) Mak KM, Lieber CS:Alterations in endothelial fenestrations in liver sinusoids of baboons fed alcohol:a scanning electron microscopic study. Hepatology 4:386-391, 1984
  pubmed

• 11) Fraser R, Bowler LM, De Zanger RB, et al:Agents related to fibrosis, such as alcohol and CCL4 acutely affect endothelial fenestrae which may cause fatty liver. in Connective tissue of the normal and fibrotic human liver. Stuttgart, Thieme Verlag, 159-160, 1982

• 12) Frenzel H, Kremer B, Richter IE, et al Der Einfluss des perfusionsdruckes bei der Perfusionsfixation auf die Feinstruktur der Lebersinusoids. Transmissions-und Rasterelektronenmikroskopische Untersuchung. Res Exp Med 168:229-241, 1976
  pubmed

• 13) Frenzel H, Kremer B, Hucker H:The liver sinusoids under various pathological conditions. A TEM and SEM study of rat liver after respiratory hypoxia, telecobalt-irradiation and endotoxin application. in Kupffer cells and other liver sinusoidal cells. Amsterdam, Elsevier, 213-222, 1977

• 14) Wisse E, Van Dierendonck JH, De Zanger RB, et al:0n the role of the liver endothelial filter in the transport of particulate fat (chylomicrons and their remnants) to parenchymal cells and the influence of certain hormones on endothelial fenestrae. in Proc Basler Liver Week. London, England, MTP Press, 195-200, 1980

• 15) Steffan AM, Gendrault JL, Kirn A:Increase in the number of fenestrae in mouse endothelial liver cells by altering the cytoskeleton with cytochalasin B. Hepatology 9:1230-1238, 1987

• 16) Wisse E, De Zanger RB, Charels K, et al:The liver sieve:considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and space of Disse. Hepatology 5:683-692, 1985

• 17) Horn T, Christoffersen P, Henriksen JH:Alcoholic liver injury:Deffenestration in noncirrhotic liver, a scanning electron microscopic study. Hepatology 7:77-82, 1987
  pubmed

• 18) Charels K, De Zanger RB, Van Bossuyt H, et al:Influence of acute alcohol administration on endothelial fenestration of rat livers:An in vivo and in vitro scanning electron microscopic study. in Cells of hepatic sinusoid. Netherlands, Kupffer Cell Fundation, 497-502, 1986

P.35 掲載の参考文献

• 1) Hirosawa K, Yamada E:The localization of the vitamin A in the mouse liver as revealed by electron microscope radioautography. J Electron Microsc 22:337, 1973
  pubmed

• 2) Hendricks HFJ, Verhoofstad WAMM, Brouwer A, et al:Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. Exptl Cell Res 160:138, 1985

• 3) McGee JO'D, Patrick RS:The role of perisinusoidal cells in hepatic fibrogenesis. An electron microscopic study of acute carbon tetrachloride liver injury. Lab Invest 26:429, 1972

• 4) Kent G, Steffen G, Inouye T, et al:Vitamin A-containing lipocytes and formation of type III collagen in liver injury. Proc Natl Acad Sci USA 73:3719, 1976

• 5) Enzan H:Ito cells (fat-storing cells) and collagen formation in acute carbon tetrachloride liver injury. A light and electron microscopic auto radiographic study using 3H-proline as a tracer. Resent Advances in RES Res 24:48, 1984

• 6) Enzan H, Hara H:Ito cells (fat-storing cells) and collagen formation in carbon tetrachloride-induced liver fibrosis. A light and electron microscopic autoradiographic study using 3H-proline as a tracer. in Cell ofthe hepatic sinusoid, ed by Kirn A, Knook DL, Wisse E. The Netherlands, The Kupffer Cell Foundation 233, 1986

• 7) Yokoi Y, Namihisa T, Kuroda H, et al:Immunocytochemical detection of desmin in fat-storing cells (Ito cells) . Hepatology 4:709, 1984
  pubmed

• 8) 横井幸男, 松崎研一郎, 宮崎招久, 他:デスミンと伊東細胞. 生体の化学 37:483, 1986

• 9) Yamamoto M, Enzan H:Morphology and function of Ito cell (fat-storing cell) in the liver. Recent Advances in RES Res 15:54, 1975

• 10) Enzan H, Hara H, Yamashita Y, et al:Fine structure of hepatic sinusoids and their development in human embryos and fetuses. Acta Pathol Jpn 33:447, 1983
  pubmed

• 11) 田平礼三:人胎児肝臓の組織発生学的研究, 特に脂肪摂取細胞について. 日組録14:495, 1958

• 12) Matsumoto E, Hirosawa K, Abe K, et al:Development of the vitamin Astoring cell in mouse liver during late fetal and neonatal periods. Anat Embryol 169:249, 1984
  pubmed

• 13) Wake K:Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int Rev Cytol 66:303, 1980
  pubmed

• 14) 0kanoue T, Burbige EJ, French SW:The role of the Ito cell in perivenular and intralobular fibrosis in alcoholic hepatitis. Arch Pathol Lab Med 107:459, 1983

• 15) Leo MA, Lieber CS:Hepatic fibrosis after long-term administration of ethanol and moderate vitamin A supplementation in the rat. Hepatology 3:1, 1983
  pubmed

• 16) Mak KIM, Leo MA, Lieber CS:Alcoholic liver injury in baboons. Transformation of lipocytes to transitional cells. Gastroenterology 87:188, 1984

• 17) Nakano M, Lieber CS:Ultrastructure of initial stages of perivenular fibrosis in alcohol-fed baboons. Am J Patho1106:145, 1982

• 18) Hruban ZH, Russel RM, Boyer JL, et al:Ultrastructural changes in livers of two patients with hypervitaminosis A. Am J Patho176:451, 1974

• 19) Jacques EA, Buschmann RJ, Layden TJ:The histopathologic progression of vitamin A-induced hepatic injury. Gastroenterology 76:599, 1979
  pubmed

• 20) Russell RM, Boyer JL, Bagheri SA, et al:Hepatic injury from chronic hypervitaminosis A resulting in portal hypertension and ascites. New Engl J Med 291:435, 1974
  pubmed

• 21) Wanless IR:The cellular distribution of vitamin A in the liver. Liver 3:403, 1983
  pubmed

• 22) Blomhoff R, Rasmussen M, Nilsson A, et al:Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells. J Biol Chem 260:13560, 1985
  pubmed

• 23) Blomhoff R, Holte K, Naess L, et al:Newly administered[3H]retinol is transfered from hepatocytes to stellate cells in liver for storage. Ex-ptl Cell Res 150:186, 1984

• 24) Yamada E, Hirosawa K:The possible existence of a vitamin A-storing cell system. Cell Struct Funct 1:201, 1976

• 25) Senoo H, Wake K:Suppression of experimental hepatic fibrosis by administration of vitamin A. Lab Invest 52:182, 1985
  pubmed

• 26) Burt AD, Robertson JL, Heir J, et al:Desmin-containing stellate cells in rat liver. Distribution in normal animals and response to experimental acute liver injury. J Pathol 150:29, 1986
  pubmed

• 27) Yokoi Y, Namihisa T, Matsuzaki K, et al:Distribution of Ito cells in experimental hepatic fibrosis. Liver 8:48, 1988
  pubmed

• 28) 横井幸男, 松崎研一郎, 黒田博之:四塩化炭素肝障害における伊東細胞 (fat-storing cell) の動態と肝線維化との関連. 肝臓26:1472, 1985

• 29) Rubin E, Hutterer F, Popper H:Experimental hepatic fibrosis without hepatocellular regeneration. Am J Pathol 52:111, 1968
  pubmed

• 30) Ballardini G, Esposti SD, Bianchi FB, et al:Correlation between Ito cells and fibrogenesis in an experimental model of hepatic fibrosis. A sequential stereological study. Liver 3:58, 1983

• 31) Enzan H:Protein synthesis in Ito cells (fat-storing cells) of cultured liver tissues from CCI4-treated mice. A light and electron microscopic autoradiographic study. Acta Pathol Jpn 37:225, 1987

• 32) Enzan H:Proliferation of Ito cells (fat-storing cells) in acute carbon tetrachloride liver injury. A light and electron microscopic autoradiographic study. Acta Pathol Jpn 35:1301, 1985
  pubmed

• 33) Tsukamoto H, Towner SJ, Ciofalo LM, et al:Ethanol-induced liver fibrosis in rats fed high fat diet. Hepatology 6:814, 1986
  pubmed

• 34) Minato Y, Hasumura Y, Takeuchi J:The role of fat-storing cells in Disse space fibrogenesis in alcoholic liver disease. Hepatology 3:559, 1983
  pubmed

• 35) Tsutsumi M, Takada A, Takase S:Characterization of desmin-positiverat liver sinusoidal cells. Hepatology 7:277, 1987
  pubmed

• 36) Senoo H, Hata RI, Nagai Y, et al:Stellate cells (vitamin A-storing cells) are the primary site of collagen synthesis in non-parenchymal cells in the liver. Biomed Res 5:451, 1984

• 37) De Leeuw AM, McCarthy SP, Geerts A, et al:Purified rat liver fatstoring cells in culture divide and contain collagen. Hepatology 4:392, 1984
  pubmed

• 38) Clement B, Grimaud JA, Campion JP, et al:Cell types involved in lagen and fibronectin production in normal and fibrotic human liver. Hepatology 6:225, 1986

• 39) Schaffer S, Zerbe O, Gressner AM:The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology 7:680, 1987

• 40) Callea F, Mebis J, Desmet UJ:Myofibroblasts in focal nodular hyperplasia of the liver. Virchows Arch[Pathol Anat]396:155, 1982

P.53 掲載の参考文献

• 1) Decker K:Trends in Hepatology. Lancaster. MTP Press Limited, 93-102, 1985

• 2) Tanikawa K:Effects of alcohol and bile acids on the endocytosis of the Kupffer cell. Proc. XIth Int Cong on Electron Microscopy, 1957-1960, 1986

• 3) 河原敏彦, 神代龍吉, 野口和典, 他:培養ラットKupffer細胞Fc receptor の電顕的観察と内因性peroxidase局在の変化. 第22回日本肝臓学会総会, 甲府, 1986, 肝臓27 (Suppl):152, 1986

• 4) Wisse E:Kupffer cells and other sinusoidal cells. North-Holland, Elsevier, 33-60, 1977

• 5) 上田 寛:培養ラットKupffer細胞のendocytosisにおけるcytochalasin Bとcolchicineの影響について. 肝臓24 (4):389-397, 1983

• 6) 野口和典:肝網内系に対する免疫賦活剤の効果. 肝臓28 (10):1306-1314, 1987

• 7) Tanikawa K, Sata M:Hepatitis virus and tissue reactions in the river. Proc. Xlth Int Cong on Electron Microscopy, 2133-2136, 1986

• 8) Tanikawa K, Sata M, Setoyama H, et al:Changes of the kupffer cell and clinical manifestations in acute hepatitis type A. Kupffer Cell Foundation Cells of Hepatic Sinusoid, Vol 1:371-376, 1986

• 9) 有高知樹:急性肝炎でのRaji細胞法による血中免疫複合体の検討. 肝臓 26 (12):1595-1603, 1985

• 10) 中野 均:A型肝炎にお・ける高IgM血症の成因に関する研究. 日本消化器病学会雑誌84 (9):1755-1763, 1987

• 11) 後野嘉宏, 佐田通夫, 鈴木宏, 他:急性ウイルス性肝炎における血清C-Reactive Proteinの動態. 肝臓29 (3):412, 1988

• 12) 河原敏彦:培養ラットKupffer細胞のendocytosisに及ぼすエタノールとアセトアルデヒドの影響について. 肝臓26 (4):428-434, 1985

• 13) 谷川久一:黄疸の成因と病理. 消化器外科10 (13):1937-1943, 1987

P.71 掲載の参考文献

• 1) Alberts B, Bray D, Lewis J, et al:The cytoskeleton In:Molecular Biology of the Cell New York, Garland Pub Inc 549-609, 1983

• 2) Rungger-Brandle E, Gabbiani G:The role of cytoskeletal and cytocontractile elements in pathologic processes. AJP 110:361-392, 1983
  pubmed

• 3) Wisse E, Knook DL:The investigation of sinusoidal cell:Anew approach to the study of liver function. In Progress in Liver Diseases Vol IV, ed by Popper H, New York, Schaffner F, Grune&Stratton, 153-172, 1979

• 4) 市田隆文, 白鳥康史:ラット培養Kupffer細胞における細胞骨格の立体構造. 肝臓26:1098, 1985

• 5) Ichida T, Shiratori Y, Wisse E:On the structure and function of the cytoskeleton in phagocytosing Kupffer cells isolated from rat liver. in:Cells of the Hepatic Sinusoid, Vol 1. ed by Kirn A, Knook DL, Wisse E. The Netherlands, The Kupffer Cell Foundation, 153-158, 1986

• 6) Brouwer A, Barelds RJ, De Leeuw AM, et al:Maintenance cultures of Kupffer cells as a tool in experimental liver research. In Sinusoidal Liver Cells. ed by Khook DL, Wisse E. Amsterdam, Elsevier Biomed, 327-334, 1982

• 7) 向坂彰太郎, 野口和典, 谷川久一, 他:肝類洞壁細胞の分離・培養. 肝胆膵 10:247-253, 1985

• 8) Penman S:New views of cell and tissue cytoarchitecture:Embedment-free electron microscopy and biochemical analysis. Hepatology 5:152-158, 1985
  pubmed

• 9) Loftus JC, Choate J, Albrecht RM:Platelet activation and cytoskeletal reorganization:high voltage electron microscopic examination of intact and triton-extracted whole mounts. J Cell Biol 98:2019-2025, 1984

• 10) Bell Jr PB:The preparation of whole cells for electron microscopy. In:Science of Biological Specimen Preparation, Chicago, SEM Inc AMF O'Hare, 45-59, 1984

• 11) Small JV:Organization of actin in the leading edge of cultured cells:Influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks. J Cell Biol 91:695-705, 1981

• 12) Beesley JE, Orpin A, Adlam C:An evaluation of the conditions necessary for optimal protein A-gold labelling of capsular antigen in ultra thin methacrylate sections of the bacterium Pasteurella haemolytica. Histochem J 16:151-163, 1984

• 13) Gamliel H, Gurfel D, Leizerowitz R, et al:Air-drying of human leucocytes for scanning electron microscopy using the GTGO procedure. J Microscopy 131:87-95, 1983
  pubmed

II. 慢性肝炎の治療

P.98 掲載の参考文献

• 1) 矢野右人, 古賀満明, 他:HBVキャリアーの自然経過. 肝胆膵7 (3):333-338, 1983

• 2) 第13回犬山シンポジウム. B型肝炎のトピックス-自然経過・HBV-DNA ・治療. 中外医学社, 東京, 1984

• 3) 瀧野辰郎, 奥野忠雄:B型慢性肝炎の治療-抗ウイルス薬と免疫賦活薬-内科57 (6):1028-1034, 1986

• 4) 古田精市, 他:HBe抗原陽性のHBsAg carrier長期観察例におけるHBe 抗原の推移. 第13回犬山シンポジウム記録. B型肝炎のトピックス, 中外医学社, 東京, 18-23, 1984

P.108 掲載の参考文献

• 1) Hoofnagle JH, Mullen KD, Jones DB, et al:Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med 315:1575, 1986

• 2) Thomson BJ, Doran M, Lever AML, et al:Alpha-interferon therapy for non-A, non-B hepatitis transmitted by gamma globulin treatment therapy. Lancet i:539, 1987

• 3) Nagashima H, Arima T, Suzuki H:Treatment of chronic non-A, non-B hepatitis with human interferon一β. J Med Virol 21:128A, 1987

• 4) Kiyosawa K, Sodeyama T, Oike Y, et al:Treatment of chronic non-A, non-B hepatitis with beta interferon. J Med Virol 21:128A, 1987

• 5) 大岡照二, 金邦源, 岸田隆:Non-A, non-B型慢性活動性肝炎への IFNαおよび免疫賦活剤投与の臨床病理学的検討. 綜合臨牀36:2063, 1987

• 6) Okuda K, Fujimoto I, Hanai A, et al:Changing incidence of hepatocellular carcinoma in Japan. Cancer Res 47:4967, 1987
  pubmed

• 7) 清沢研道, 赤羽賢浩, 小池ゆり子, 他:非A非B型慢性肝疾患における輸血歴の意義について. 日消誌79:46, 1982

• 8) 白木和夫:非A非B型肝炎の垂直感染に関する研究, 厚生省特定疾患難治性の肝炎調査研究班 昭和60年度研究報告書, 23, 昭和61年3月発行

P.120 掲載の参考文献

• 1) Robinson WS, et al:The hepadna viruses of animals. Semin Liver Dis 4:347-360, 1984
  pubmed

• 2) 鈴木 宏:Ara-A, Ara-AMP, IFN-αおよびIFN-βによる慢性B型肝炎の治療, 厚生省特定疾患難治性の肝炎調査研究班, 昭和56年度研究報告, 29-35

• 3) 飯野四郎, 他:インターフェロン-βの血中HBe抗原量に対する効果. 肝臓25:1501, 1984

• 4) Yokosuka O, Omata M, Imazeki F, et al:Changes of hepatitis B virus D NA in liver and serum caused by recombinant leukocyte interferon treatment. Hepatology 5:728-734, 1985

• 5) 鈴木宏, 他:HBe抗原陽性慢性肝炎に対するインターフェロン-β療法. 肝胆膵 9:611-631, 1984

• 6) 私信による

• 7) 飯野四郎, 日野邦彦, 他:B型慢性肝炎に対するインターフェロン短期反復療法. B型慢性肝炎の治療, 国際医書出版, 72-79, 1987

P.130 掲載の参考文献

• 1) Muller WEG, Zahn AK, Brittlingmaier K, et al:Inhibition of herpesvirus DNA synthesis by 9-β-D-arabinofuranosyladenine in cellular and cell-free systems. Ann NY Acad Sci 284:34-48, 1977

• 2) Whitley RJ, Soong SJ, Hirsh MS, et al:Herpes simplex encephalitis. Vidarabine therapy and diagnostic problem. N Engl J Med 304:313-318, 1981

• 3) Pollard RB, Smith JL, Neal A, et al:Effect of vidarabine on chronic hepatitis B virus infection. JAMA 239:1648-1650, 1978
  pubmed

• 4) 市田文弘, 鈴木司郎, 松嶋 喬, 他:慢性B型肝炎に対するAra-A (Vi・ darabine) の臨床効果の検討. 肝胆膵15:993-1002, 1987

P.141 掲載の参考文献

• 1) Kakumu S, Fuji A, Yoshioka K, et al:Pilot study of recombinant human interleukin 2 for chronic type B hepatitis. Hepatology 8:487, 1988
  pubmed

• 2) Fuji A, Kakumu S, Ohtani Y, et al:Interferon-γ production by peripheral blood mononuclear cells of patients with chronic liver disease. Hepatology 7:577, 1987

• 3) 笠倉新平:免疫学の進歩-リンホカイン, IL-2を中心に-週間医学界新 聞臨時増刊1562号, 医学書院, 東京, 46, 1983

• 4) 山本祐夫, 溝口靖紘, 阪上吉秀, 他:B型慢性肝炎に対するrecombinant IL-2投与の影響. 厚生省難治性の肝炎調査研究班, 昭和60年度研究報告, 361, 1987

• 5) Kato K, Yamada T, Kawahara K, et al:Purification and chracterization of recombinant human interleukin 2. Biochem Biophys Res Commun 130:692, 1985

• 6) Rosenberg SA, Lotze MT, Muul LM, et al:Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. N Engl J Med 313:1485, 1985
  pubmed

P.153 掲載の参考文献

• 1) 牧坂泰治, 岡 富子, 松原龍男, 他:慢性肝炎に対する小柴胡湯, 桂枝茯苓丸の治療効果. 臨床と研究57:3803-3808, 1980

• 2) 岡 博, 藤原研司, 林 茂樹, 他:慢性肝炎患者における小柴胡湯なら びに桂枝茯苓丸投与と肝機能検査の変動. 肝胆膵9:825-785, 1985

• 3) 早川政兼, 皆川伸子, 雨谷 栄, 他:マウスCCl4肝硬変に対する柴胡剤 (小柴胡湯, 大柴胡湯) の効果. 第30回日本生薬学会, 1983

• 4) 池本吉博, 溝口靖紘, 新井孝之, 他:小柴胡湯および大柴胡湯のin vitro における抗体産生に及ぼす影響. 和漢医薬学会誌1:235-242, 1984

• 5) 石井公道, 鈴木 修, 桐生恭好, 他:ヒスチジン脱炭酸酵素阻害剤の慢性活動性肝炎に及ぼす影響. 日消誌74:1187-1194, 1977

• 6) 矢野右人, 古賀満明, 南野 毅:トリトカリン (Tritoqualine:TRQ) の慢性肝炎に対する治療効果の検討. 薬理と治療14:1769-1780, 1986

• 7) 矢野右人, 市田文弘, 鈴木宏, 他:慢性肝炎に対するトリトカリンの効果-多施設二重盲検法による群間比較試験-. 肝胆膵13:781-796, 1986

• 8) 鈴木宏, 市田文弘, 瀧野辰郎, 他:トリトカリンの慢性肝炎に対する臨床評価-多施設二重盲検法による群間比較試験 (1日600mg, 12週間投与)-. 肝胆膵 13:1175-1192, 1986

• 9) Suzuki K, Yamada Y, Umezu K:Inhibitory Effect of Tritoqualine orp O2 Production and Lysasomal Enzyme Release from Polymorphonuclear Leucocytes and Macrophages in Rats. 基礎と臨床20:2351-2355, 1986

• 10) 梅津浩平, 湯浅 聡, 中尾吉秀:GOT, GPTの漏出からみたラット分離肝細胞障害の差異と薬物による漏出抑制効果. 薬理と治療14:6081-6087, 1986

• 11) 梅津浩平, 湯浅 聡, 須藤敦子, 他:トリトカリン (TRQ) による肝線維化亢進の抑制作用. 日薬理誌87:291-300, 1986

• 12) 鈴木 宏, 太田康幸, 瀧野辰郎, 他:強力ネオミノファーゲンCの慢性肝炎に対する治療効果について-二重盲検法による検討-. 医学のあゆみ 102:562-578, 1977

• 13) 日野邦彦, 宮原 透, 宮川 浩, 他:慢性肝疾患に対する強力ネオミノファーゲンCの大量 (100ml)療法. 肝胆膵3:137-146, 1981

• 14) Knodell RG, Ishak KG, Black WC, et al:Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1:431-435, 1981
  pubmed

• 15) Greenberg HB, Pollard RB, Lutwik LI, et al:Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med 295:517-522, 1976

• 16) 鈴木 宏, 市田文弘, 藤沢 冽, 他:HBe抗原陽性慢性肝炎におけるインターフェロン-β療法. 肝胆膵9:611-631, 1984

• 17) Hoofnagle JH, Mullen KD, Jones DB, et al:Treatment of chronic non A, non B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med 315:1575-1578, 1986
  pubmed

• 18) 進藤道子, 奥野忠雄, 松本昌之, 他:B型慢性肝炎でのインターフェロン 療法時の血清中2'-5' oligoadenylate synthetase活性測定の臨床的意義. 肝臓28:675-680, 1987