書籍詳細

Chapter1 分類と適応

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• 2) 日本高血圧学会高血圧治療ガイドライン作成委員会:高血圧治療ガイドライン2004. ライフサイエンス出版, 東京, 2004, pp19

• 3) Pitt B, Zannad F, Remme WJ et al:The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341:709-717, 1999

• 4) Pitt B, Remme W, Zannad F et al:Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 348:1309-1321, 2003
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• 5) Ruzicka M, Leenen FH:Combination therapy as first-line treatment of arterial hypertension. Can J Cardiol 18:1317-1327, 2002
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• 6) Dezii CM:A retrospective study of persistence with single-pill combination therapy vs. concurrent two-pill therapy in patients with hypertension. Manag Care 9 (Suppl 9):2-6, 2000

Chapter2 薬理作用, 作用部位

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• 2) Kwon TH, Frokiaer J, Fernandez-Llama P et al:Altered expression of Na transporters NHE-3, NaPi-II, Na-K-ATPase, BSC-1, and TSC in CRF rat kidneys. Am J Physiol 277 (2 Pt 2):F 257-F 270, 1999

• 3) Nogae S, Michimata M, Kanazawa M et al:Cardiac infarcts increase sodium transporter transcripts (rBSC1) in the thick ascending limb of Henle. Kidney Int 57:2055-2063, 2000
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• 4) Volpe M, Magri P, Rao MA et al:Intrarenal determinants of sodium retention in mild heart failure:effects of angiotensin-converting enzyme inhibition. Hypertension 30 (2 Pt 1):168-176, 1997

• 5) Schrier RW, Abraham WT:Hormones and hemodynamics in heart failure. N Engl J Med 341:577-585, 1999
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• 6) Shipley RE, Study RS:Changes in renal blood flow, extraction of inulin, glomerular filtration rate, tissue pressure and urine flow with acute alterations of renal artery blood pressure. Am J Physiol 167:676-688, 1951
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• 7) 伊藤貞嘉:尿はなぜ作られる-暴飲暴食が可能なわけ-:腎疾患のとらえかた-眼でみるベッドサイドの病態生理. 文光堂, 東京, 2003, pp7-18

• 8) 伊藤貞嘉:二次性高血圧. メディカルレビュー社, 東京, 2003

• 9) 日本高血圧学会高血圧治療ガイドライン作成委員会:高血圧治療ガイドライン2004. ライフサイエンス出版, 東京, 2004

• 10) 伊藤貞嘉:特集 心腎疾患の病態と対策. 心血管疾患と腎疾患の連関. 血圧 14;260-265, 2007

Chapter3 病態と治療

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• 2) Conway J, Lauwers P:Hemodynamic and hypotensive effects of long-term therapy with chlorothiazide. Circulation 21:21-27, 1960
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• 3) SHEP Cooperative Research Group:Prevention of stroke by anti-hypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP) . JAMA 265:3255-3264, 1991

• 4) ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group:Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic:The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) . JAMA 288:2981-2997, 2002
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• 5) Psaty BM, Lumley T, Furberg CD et al:Health outcomes associated with various antihypertensive therapies used as first-line agents:a network meta-analysis. JAMA 289:2534-2544, 2003
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• 6) National High Blood Pressure Education Program Coordinating Committee:The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure:the JNC 7 report. JAMA 289:2560-2572, 2003

• 7) PROGRESS Collaborative Group:Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 358:1033-1041, 2001
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• 8) Zhang H, Thijs L, Staessen JA:Blood pressure lowering for primary and secondary prevention of stroke. Hypertension 48:187-195, 2006
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• 9) Dahlof B, Sever PS, Poulter NR et al:Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial Blood Pressure Lowering Arm (ASCOT-BPLA):a multicentre randomised controlled trial Lancet 366:895-906, 2005
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• 3) PROGRESS Collaborative Group:Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 358:1033-1041, 2001
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• 4) ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group:Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic:The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALL-HAT) . JAMA 288:2981-2997, 2002

• 5) Numabe A, Uehara Y, Hirawa N et al:Effects of thiazide diuretic on vascular eicosanoid system of spontaneously hypertensive rats. J Hypertens 7:493-499, 1989
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• 6) Kaste M, Roine RO:Chapter 51. General Stroke Management and Stroke Units. Stroke:Pathophysiology, Diagnosis And Management (Mohr JP, Choi DW, Grotta JC et al eds) Churchill Livingstone, Philadelphia, 2004, pp 975-977

• 7) Xi G, Keep RF, Hoff JT:Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 5:53-63, 2006
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• 8) Davies DC:Blood-brain barrier breakdown in septic encephalopathy and brain tumours. J Anat 200:639-646, 2002
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• 9) Tao RC, Kelley RE, Yoshimura NN et al:Glycerol:its metabolism and use as an intravenous energy source. JPEN J Parenter Enteral Nutr 7:479-488, 1983
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• 10) Broderick JP, Hacke W:Treatment of acute ischemic stroke:Part II:neuroprotection and medical management. Circulation 106:1736-1740, 2002
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• 11) Vorstrup S:Tomographic cerebral blood flow measurements in patients with ischemic cerebrovascular disease and evaluation of the vasodilatory capacity by the acetazolamide test. Acta Neurol Scand S 114:1-48, 1988

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• 14) Millichap JG, Woodbury DM, Goodman LS:Mechanism of the anticonvulsant action of acetazoleamide, a carbonic anhydrase inhibitor. J Pharmacol Exp Ther 115:251-258, 1955
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P.72 掲載の参考文献

• 1) Crowley SD, Gurley SB, Herrera MJ et al:Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A 103:17985-17990, 2006
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• 2) Sarnak MJ, Levey AS, Schoolwerth AC et al:Kidney disease as a risk factor for development of cardiovascular disease:a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108:215-2169, 2003

• 3) 急性心不全治療ガイドライン (2006年改訂版) (日本循環器学会ホームページ http://www.j-circ.or.jp/guideline/index.htm)

• 4) 慢性心不全治療ガイドライン (2005年改訂版) (日本循環器学会ホームページ http://www.j-circ.or.jp/guideline/index.htm)

P.80 掲載の参考文献

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• 2) Ardaillou R, Dussaule JC:Role of a trial natriuretic peptide in the control of sodium balance in chronic renal failure. Nephron 66:249-257, 1994

• 3) Lohmeier TE, Hildebrandt DA, Hood WA:Renal nerves promote sodium excretion during long-term increases in salt intake. Hypertension 33 (1 Pt 2):487-492, 1999

• 4) Brewster UC, Setaro JF, Perazella MA:The renin-angiotensin aldosterone system:cardiorenal effects and implications for renal and cardiovascular disease states. Am J Med Sci 326:15-24, 2003
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• 5) Schrier RW:Pathogenesis of sodium and water retention in high-output and low-output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy (1) . N Engl J Med 319:1065-1072, 1988
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• 6) Andreucci M, Russo D, Fuiano G et al:Diuretics in renal failure. Miner Electrolyte Metab 25:32-38, 1999
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• 7) Rudy DW, Voelker JR, Greene PK et al:Loop diuretics for chronic renal insufficiency:a continuous infusion is more efficacious than bolus therapy. Ann Intern Med 115:360-366, 1991
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• 8) Knauf H, Mutschler E:Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure. J Cardiovasc Pharmacol 26:394-400, 1995
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• 9) Ninomiya T, Kiyohara Y, Kubo M et al:Chronic kidney disease and cardiovascular disease in a general Japanese population:the Hisayama Study. Kidney Int 68:228-236, 2005

• 10) 松本 朗, 鈴木洋通, 猿田享男:フロセミド抵抗性浮腫に対するトリパミド (ノルモナール) の併用療法. 診断と治療 82:1041-1045, 1994

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• 2) Colas B, Slama M, Masson H et al:Direct vascular actions of methyclothiazide and indapamide in aorta of spontaneously hypertensive rats. Fundam Clin Pharmacol 14:363-368, 2000
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• 3) Zhu Z, Zhu S, Liu D et al:Thiazide-like diuretics attenuate agonistinduced vasoconstriction by calcium desensitization linked to Rho kinase. Hypertension 45:233-239, 2005
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• 4) Pickkers P, Russel FG, Thien T et al:Only weak vasorelaxant properties of loop diuretics in isolated resistance arteries from man, rat and guinea pig. Eur J Pharmacol 466:281-287, 2003
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• 5) Nagata D, Takahashi M, Sawai K et al:Molecular mechanism of the inhibitory effect of aldosterone on endothelial NO synthase activity. Hypertension 48:165-171, 2006
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• 6) Keidar S, Kaplan M, Pavlotzky E et al:Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development:a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. Circulation 109:2213-2220, 2004
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• 7) Rocha R, Rudolph AE, Friedich GE et al:Aldosterone induces a vascular inflammatory phenotype in the rat heart. Am J Physiol Heart Circ Physiol 283:H 1802-H 1810, 2002

• 8) Celik T, Iyisoy A, Kursaklioglu H et al:Eplerenone suppresses neointima after coronary stenting in pigs:could it be extrapolated to stent restenosis in humans? Int J Cardiol 115:97-98, 2007
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• 2) SHEP Cooperative Research Group:Prevention of stroke by anti-hypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP) . JAMA 265:3255-3264, 1991

• 3) Franse LV, Pahor M, Di Bari M et al:Hypokalemia associated with diuretic use and cardiovascular events in the Systolic Hypertension in the Elderly Program. Hypertension 35:1025-1030, 2000
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• 4) Franse LV, Pahor M, Di Bari M et al:Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP) J Hypertens 18:1149-1154, 2000
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• 5) Inaba M, Noguchi Y, Yamamoto T et al:Effects of a low dose of indapamide, a diuretic, given daily or every-other-day on blood pressure and metabolic parameters. Hypertens Res 827:141-145, 2004
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• 7) Whelton PK, Barzilay J, Cushman WC et al:Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia:Antihypertensive and Lipid-Lowering treatment to Prevent Heart Attack Trial (ALLHAT) . Arch Intern Med 165:1401-1409, 2005
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• 8) SHEP Collaborative Research Group:Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes. Am J Cardiol 95:29-35, 2005

P.97 掲載の参考文献

• 1) Marre M, Puig JG, Kokot F et al:Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes. The NESTOR study. J Hypertens 22:1613-1622, 2004
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• 2) Neaton JD, Wentworth D:Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group. Arch Intern Med 152:56-64, 1992

• 3) Halperin RO, Sesso HD, Ma J et al:Dyslipidemia and the risk of incident hypertension in men. Hypertension 47:45-50, 2006
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• 4) SHEP Cooperative Research Group:Prevention of stroke by anti-hypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP) . JAMA 265:3255-3264, 1991

• 5) ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group:Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic:The Antihypertensive and Lipid-Lowering treatment to Prevent Heart Attack Trial (ALLHAT) . JAMA 288:2981-2997, 2002
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• 6) Sever PS, Dahlof B, Poulter NR et al:Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA):a multicentre randomized controlled trial. Lancet 361:1149-1158, 2003

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• 4) Wing LM, Reid CM, Ryan P et al;Second Australian National blood Pressure Study Group:A comparison of outcomes with angiotensin-converting-enzyme inhibitor and diuretic for hypertension in the elderly. N Engl J Med 348:583-592, 2003

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• 7) ADVANCE Collaborative Group:Effects of a fix combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial):a randomised controlled trial. Lancet 370:829-840, 2007

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• 1) 伊藤貞嘉 編:腎疾患のとらえかた. 文光堂, 東京, 2003

• 2) 木村時久, 太田耕造:高齢者の電解質代謝異常と精神神経症状. 老年神経医学雑誌 16:672-680, 2005

• 3) Loffing J:Paradoxical antidiuretic effect of thiazides in diabetes insipidus:another piece in the puzzle. J Am Soc Nephrol 2004; 15:2948-2950

Chapter4 EBM

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• 1) Psaty BM, Lumley T, Furberg CD et al:Health outcomes associated with various antihypertensive therapies used as first-line agents:a network meta-analysis. JAMA 1289:2534-2544, 2003

• 2) Blood Pressure Lowering Treatment Trialists' Collaboration:Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus:results of prospectively designed overviews of randomized trials. Arch Intern Med 165:1410-1419, 2005
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• 4) Neaton JD, Grimm RH Jr, Prineas RJ et al:Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group. JAMA 270:713-724, 1993

• 5) Liebson PR, Grandits GA, Dianzumba S et al:Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapyin the Treatment of Mild Hypertension Study (TOMHS) . Circulation 91:698-706, 1995

• 6) 木村玄次郎:高血圧治療と利尿薬. 呼吸と循環 54:71-80, 2006

• 7) Uzu T, Kimura G:Diuretics shift circadian rhythm of blood pressure from nondipper to dipper in essential hypertension. Circulation 100:1635-1638, 1999
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• 8) Saito F, Kimura G:Antihypertensive mechanism of diuretics based on pressure-natriuresis relationship. Hypertension 27:914-918, 1996
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• 9) Wassertheil-Smoller S, Psaty B, Greenland P et al:Association between cardiovascular outcomes and antihypertensive drug treatment in older women. JAMA 292:2849-2859, 2004
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• 10) PROGRESS Collaborative Group:Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6, 105 individuals with previous stroke or transient ischaemic attack. Lancet 358:1033-1041, 2001
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• 11) Carey PA, Sheridan DJ, de Cordoue A et al:Effect of indapamide on left ventricular hypertrophy in hypertension:ameta-analysis. Am J Cardiol 77:17b-19b, 1996

• 12) 沼部敦司, 上原譽志夫, 八木繁ほか:高血圧自然発症ラットの血管壁エイコサノイド系に及ぼすサイアザイド系利尿薬の影響とその作用機序. 日本腎臓学会雑誌 30:1339-1347, 1988

• 13) Dahlof B, Devereux RB, Kjeldsen SE et al:Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE):a randomised trial against atenolol. Lancet 359:995-1003, 2002
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• 14) Brenner BM, Cooper ME, de Zeeuw D et al:Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 345:861-869, 2001
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• 15) 猿田享男:日本における降圧薬合剤の歴史・変遷-ARB/利尿薬合剤誕生の経緯-. 血圧 13:1297-1300, 2006
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• 16) 斉藤郁夫:ARB/利尿薬合剤と服薬コンプライアンス. 血圧 13:1354-1357, 2006

• 17) Conlin PR, Spence JD, Williams B et al:Angiotensin II antagonists for hypertension:are there differences in efficacy? Am J Hypertens 13 (4 Pt 1):418-426, 2000

• 18) 福岡富和, 大蔵隆文, 檜垣實男:利尿薬とR-A系抑制薬の併用治療の評価. 循環器科 55:235-242, 2004

• 19) Kostis JB, Wilson AC, Freudenberger RS et al:Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes. Am J Cardiol 95:29-35, 2005

• 20) Barzilay JI, Davis BR, Cutler JA et al:Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment:a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) . Arch Intern Med 166:2191-2201, 2006
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• 23) Chobanian AV, Bakris GL, Black HR et al:The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure:the JNC 7 Report. JAMA 289:2560-2572, 2003
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• 24) Mancia G, De Backoer G, Dominiczak A et al; Management of Arterial Hypertension of the European Society of Hypertension; European Society of Cardiology:2007 Guideline for the Management of Arterial Hypertension:The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) . J Hypertens 25:1105-1187, 2007

Chapter5 併用療法

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Chapter6 症例の実際(Q&A)

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Chapter7 使用上の注意・薬物相互作用

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