書籍詳細

第I章 糖尿病の概念と分類

P.1 掲載の参考文献

• 1) 葛谷信貞, 阿部正和, 上田英雄, 葛谷覚元, 葛谷健, 小坂樹徳, 後藤由夫, 繁田幸男, 馬場茂明, 平田幸正, 堀内光, 山田弘三, 和田正久 : 糖負荷試験による糖尿病診断基準委員会報告, 糖尿病の診断に用いるための糖負荷試験の判定基準についての報告. 糖尿病, 13 : 1-7, 1970

• 2) 小坂樹徳, 赤沼安夫, 後藤由夫, 羽倉綾子, 平田幸正, 川手亮三, 葛谷健, 三村悟郎, 中山秀隆, 坂本信夫, 繁田幸男 : 糖尿病の診断に関する委員会報告. 糖尿病, 25 : 859-866, 1982

• 3) National Diabetes Data Group : Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes, 28 : 1039-1057, 1979.

• 4) WHO Expert Committee on Diabetes Mellitus. Second Report. Technical Report Series 646, WHO, Geneva, 1980.

• 5) Diabetes Mellitus, Report of a WHO Study Group.Technical Report Series 727, WHO, Geneva, 1985.

• 6) 小林哲郎 : Slowly progressive IDDM. 糖尿病学1983, 小坂樹徳編, 診断と治療社, 東京, p205-224, 1983.

• 7) Cerasi, E., Luft, R.: "What is inherited-What is added", hypothesis for the pathogenesis of diabetes mellitus. Diabetes, 16 : 615-627, 1967.
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• 8) Kosaka, K., Hagura, R., Kuzuya, T.: Insulin responses in equivocal and definite diabetes, with special reference to subjects who had mild glucose intolerance but later developed definite diabetes. Diabetes, 26 : 944-952, 1977.
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• 9) Kadowaki, T., Miyake, Y., Hagura, R., Akanuma, Y., Kajinuma, H., Kuzuya, T., Takaku, F., Kosaka, K.: Risk factors for worsening to diabetes in subjects with impaired glucose tolerance. Diabetologia, 26 : 44-49, 1984.

• 10) Tattersall, R. B., Fajans, S. S.: A difference between the inheritance of classic juvenile-onset and maturity-onset diabetes of young people. Diabetes, 24 : 44-53, 1975.
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• 11) Hugh-Jones, P.: Diabetes in Jamaica. Lancet, ii : 891-897, 1955.

• 12) Rao, R. H.: Diabetes in the undernourished : Coincidence or consequence? Endocr. Review, 9 : 67-87, 1988.
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• 13) 小坂樹徳 : 糖尿病-病型分類と診断に関する最近の動向. 糖尿病学1980, 小坂樹徳編, 診断と治療社, 東京, p1-29, 1980.

• 14) Unger, R. H., Foster, D. W.: Diabetes Mellitus. Textbook of Endocrinology, 7th Edition, Wilson, J. D. et al. (eds), W. B. Saunders Company, Philadelphia, p.1018-1080, 1985.

• 15) Unger & Foster糖尿病学. Textbook of Endocrinology, 佐々木英夫他監訳, HBJ出版局, 東京, p5, 1988

第II章 糖尿病の病態生理

P.13 掲載の参考文献

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• 1) Bell, G. I., Pictet, R. L., Rutter, W. J., Cardell, B., Tischer, E., Goodman, H. M.: Sequence of the human insulin gene. Nature, 284 : 26-32, 1980.

• 1) 清野裕 : 代謝異常. Current therapy, 5 : 999-1003, 1987

• 1) Colwell, J. A., Winocour, P. D., Lopes-Virella M. F., Halushka, P. V.: New concepts about the pathogenesis of atherosclerosis in diabetes mellitus. Am. J. Med., 75 (B) : 67-80, 1983.

• 1) Mayes, P. A.: Lipid transport & storage. Harper's Biochemistry, Murray, R. K. et al. (eds), Appleton & Lange, Connecticut, p226-240, 1988.

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• 2) Fredrickson, D. S., Levy, R. I., Lees, R. S.: Fat transport in lipoprotein. A integrated approach to mechanism and disorders, N. Engl. J. Med., 276 : 32-44, 94-103, 148-156, 215-226, 273-281, 1967.

• 2) Karam, J. H., Salber, P. R., Forsham, P. H.: Pancreatic hormones and diabetes mellitus. Basic and clinical endocrinology, Greenspan, F. S. et al. (eds), Lange and Marzen, Singapore, p500-545, 1983.

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• 3) Hamberg, M., Svensson, S., Samuelsson, B.: Thromboxanes : a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci., 72 : 2994-2998, 1975.

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• 4) 河盛隆造, 七里元亮 : グルカゴン分泌異常は糖尿病の一次的特質か. ホルモンと臨床, 33 : 225-228, 1985.

• 4) 堅田利明 宇井理生 : アデニレート-シクラーゼ系 : 受容体と情報伝達. 宇井理生編 現代化学増刊4, 東京化学同人, 東京, p28-47, 1985.

• 4) Ohlsson, H., Edlund, D.: Sequence-specific interaction of nuclear factors with the insulin gene enhancer, Cell, 45 : 35-44, 1986.

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• 4) 荒木栄一, 七里元亮, 蛯名洋介 : インスリン受容体遺伝子と発現調節. BIO medica, 4 : 247-252, 1989.

• 4) Mahley. R. W., Innerarity, T. L., Rall, Jr. S. C., Weisgraber, K. H.: Plasma lipoproteins : apolipoprotein structure and function. J. Lipid Res., 25 : 1277-1298, 1985.

• 5) 室田誠逸 : アラキドン酸カスケード. 現代化学増刊, プロスタグランジンと病態, 室田誠逸編, 東京化学同人社, 東京, p3-37, 1985.

• 5) Unger, R. H., Orci, L.: Glucagon and the A cell-physiology and pathophysiology. N Engl. J. Med., 304 : 1518-1524, 1575-1580, 1981.

• 5) Fredrickson, D. S., Goldstein, J. L., Brown. M D.: The familial hyperlipoproteinemia. Themetabolic basis of inherited disease. Stanbury J. B. et al. (eds), McGraw Hill, New York, p604-730, 1978.

• 5) Seino, S., Seino, M., Nishi, S., Bell, G. I.: Structure of the human insulin receptor gene and characterization of its promoter. Proc. Natl. Acad. Sci., 86 : 114-118, 1989.
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• 5) Howell, S. L., Tyhurst ; M.: The insulin storage granule. The Secretory Granule, Poisner, A. M. et al (eds), Elsevier Biomedical, Amsterdam, p155-172, 1982.

• 5) Magnuson, M. A., Andreone, T. L., Printz, R. L., Koch, S., Granner, D. K.: Rat glucokinase gene, structure and regulation by insulin. Proc. Natl. Acad. Sci., 86 : 4838-4842, 1989.
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• 6) Heath, H., Brigden, W. D., Canever, J. V.: Platlet adhesiveness and aggregation in relation to diabetic neuropathy. Diabetologia, 7 : 308-315, 1971.

• 6) Hutton, J. C.: The insulin secretory granule. Diabetologia, 32 : 271-281, 1989.
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• 6) Shichiri, M., Kawamori, R., Abe, H.: Normalization of the paradoxic secretion of glucagon in diabetics who were controlled by the artificial beta cell. Diabetes, 28 : 272-275, 1979.
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• 6) Kadonaga, T. T., Carner, K. R., Masiarz, F. R., Tijian, R.: IsoIation of cDNA encoding transcription factor Sp 1 and functional analysis of the DNA binding domain. Cell, 51 : 1079-1090, 1987.

• 6) Mueckler, M., Caruso, C., Baldwin, S. A., Panico, M., Blench, I., Morris, H. A., Allard, W. J., Lienhard, G. E., Lodish, H. F.: Sequence and structure of a human glucose transporter. Science, : 941-945, 1985.

• 6) Carson, L. A., Bottiger, L. E., Ahfeld, P. E.: Risk factors for myocardial infarction on the Stockholm prospective study. Acta Med. Scand., 206 : 351-366, 1979.

• 7) Butkus, A., Skrinska, V. A., Schumacher, O. P.: Thromboxane production and platelet aggregation in diabetic subjects with clinical complication. Thromb. Res., 19 ; 211-223, 1980.

• 7) Ebina, Y., Araki, E., Taira, M., Shimada, F., Mori, M., Craik, C., Siddle, K., Pierce, S., Roth, R., Rutter, W. J.: Replacement of Iysine residue 1,030 in the putative ATP-binding region of the insulin receptor abolishes insulin-and antibody-stimulated glucose uptake and receptor kinase activity. Proc. Natl. Acad. Sci., 84 : 704-708, 1987.

• 7) Niki, A., Niki, H., Miwa, I., Okuda, J.: Insulin secretion by anomers of D-glucose. Science, 186 : 150-151, 1974.
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• 7) Kannel, W. B., Castelli, W. P., Gordon, T.: Cholestrol in the prediction of atherosclerotic disease. New perspectives based on the Framingham Study. Ann. Inten. Med., 90 : 85-91, 1979.

• 7) Kawamori, R., Shichiri, M., Kikuchi, M., Yamasaki, Y., Abe, H.: Perfect normalization of excessive glucagon responses to intravenous arginine in human diabetes mellitus with the artificial beta-cell. Diabetes, 29 : 762-765, 1980.
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• 7) Birnbaum, M. J., Haspel, H. C., Rosen, O. M.: Cloning and characterization of a cDNA encoding the rat brain glucose transporter protein. Proc. Natl. Acad. Sci., 82 : 5784-5788, 1986.

• 8) 桂賢, 鮴谷佳和, 岩間令道, 河盛隆造, 七里元亮, 阿部裕 : グルカゴン分泌特性の解明-低血糖刺激時グルカゴン分泌特性におよぼす糖代謝状態と自律神経機能の関連性について-. 糖尿病, 28 : 101-108 1985.

• 8) Sagel, J., Colwell, J. A., Crook, L., Laimins, L.: Increased platelet aggregation in early diabets mellitus. Ann. Intern. Med., 82 : 733-738, 1975.

• 8) Chou, C. K., Dull, T. J., Russell, D. S., Cherzi, R., Lebwohl, D., Ullrich, A., Rosen, O. M.: Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J. Biol. Chem., 262 : 1842-1847, 1987.

• 8) Beisiegel, U., Weber, W., Havinga, J. R., Ihrke, G., Hui, D. Y., Wernette-Hammond, M. E., Truck, C. W., Innerarity, T. L., Mahley, R. W.: Apolipoprotein E-binding proteins isolated from dog and human liver. Arteriosclerosis, 8 : 288-297, 1988.

• 8) Asano, T., Shibasaki, Y., Kasuga, M., Kanazawa, Y., Takaku, F., Akanuma, Y., Oka, T.: Cloning of rabbit brain glucose transporter cDNA and alteration of glucose transporter mRNA during tissue developement. Biochem. Biophys. Res. Commun., 154 : 1204-1211, 1988.

• 8) Malaisse, W. J., Best, L., Kawazu, S., Malaisse-Lagae, F., Sener, A.: The stimulus-secretion coupling of glulcose-induced insulin release : fuel metabolism in islets deprived of exogenous nutrient. Arch. Biochem. Biophys., 224 : 102-110, 1983.
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• 9) Olefsky, J. M.: Insulin resistance and insulin action. an in vitro and in vivo perspective. Diabetes, 30 : 148-162, 1982.

• 9) Findling, J. W., Tyrell, J. B.: Anterior pituitary and somatomedins, I. Anterior pituitary. Basic and clinical endocrinology, Greenspan, F. S. et al. (eds), Lange and Maruzen, Sigapore, p38-88, 1983.

• 9) Ahren, B., Taborsky, G. J., Porte, D. Jr.: Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia, 29 : 827-836, 1986.
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• 9) Fukumoto, H., Seino, S., Imura, H., Seino, Y., Eddy, R. L., Fukushima, Y., Byers, M. G., Shows, T. B., Bell, G. I.: Sequence tissue distribution, and chromozomal localization of mRNA encoding a human glucose transporter like protein. Proc. Natl. Acad. Sci., 85 : 5434-5438, 1988.

• 9) Brown, M. S., Goldstein, J. L.: How LDL receptors influence cholesterol and atherosclerosis. Sci. Am., 251 : 52-70, 1984.

• 9) Jones, D. B., Davis, T. M. E., Brown, E., Carter, R. D., Mann, J. I., Prescott, R. J.: Determinants of ADP-induced platelet aggregation in diabetes mellitus. Diabetologia, 29 : 291-294, 1986.

• 10) MacGorman, L. R., Rizza, R. A., Gerich, J. E.: Physiological concentrations of growth hormone exert insulin-like and insulin antagonistic effects on both hepatic and extrahepatic tissues in man. J. Clin. Endocrnol. Metab., 53 : 556-559, 981.

• 10) Schneider, W. J., Beisiegel, U., Goldstein, J. L., Brown, M. S.: Purification of the low density lipoprotein receptor, an acidic glycoprotein of 164,000 molecular weight J. Biol. Chem., 257 : 2664-2673, 1982.
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• 10) Defronzo, R. A., Tobin, J. D., Andres, R.: Glucose clamp technique. a method for quantifying insulin secretion and resistance. Am. J. Physiol., 237 : E214-223, 1979.
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• 10) Abrahamsen, A. F.: Platelet survival studies in man with special reference to thrombosis and atherosclerosis. Scand. J. Hematol., 3 (Suppl) : 7-53, 1968.

• 10) Pipeleers, D.: The biosociology of pancreatic B cells. Diabetologia, 30 : 277-291, 1987.
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• 10) Thorens, B., Sarkar, H. K., Kaback, H. R., Lodish, H. F.: Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells. Cell, 55 : 281-290, 1988.

• 11) Hediger, M. A., Coady, M. J., Ikeda, T. S., Wright, E. M.: Expression, cloning and cDNA sequences of the Na+/glucoce cotransporter. Nature, 330 : 379-381, 1987.

• 11) 村瀬敏郎, 山田信博 : 後天性リポ蛋白異常. 血漿リポタンパク, 赤沼安夫他編, 講談社, 東京, p243, 1983.

• 11) 出村博, 出村黎子 : 下垂体ホルモン. 日本臨牀, 40 : 315-320, 1982.

• 11) Jones, R. L., Paradise, C., Peterson, C. M.: Platelet survival in patients with diabetes mellitus. Diabetes, 30 : 486-489, 1981.
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• 11) Zawalich, W., Zawalich, K., Rasumssen, H.: Insulin secretion : Combined tolbutamide, forskolin and TPA mimic action of glucose. Cell Calcium, 5 : 551-558, 1984.

• 11) Kolterman, O. G., Gray, R. S., Griffin, J., Burstein, P., Insel, J., Scarlett, J. A., Olefsky, J. M.: Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellites. J. Clin. Invest., 68 : 957-969, 1981.

• 12) Goldstein, J. L., Brown, M. S.: Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol. J. Lipid Res., 25 : 1450-1461, 1984.
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• 12) Hansen, A. P., Johansen, K.: Diurnal patterns of blood gulcose, serum free fatty acids, insulin, glucagon and growth hormone levels in normals and juvenile diabetics. Diabetologia, 6 : 27-33, 1970.

• 12) Freidenberg, G. R., Henry, R. R., Klein, H. H., Reichart, D. R., Olefsky, J. M.: Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. J. Clin. Invest., 79 : 240-250, 1987.
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• 12) Fukumoto, H., Kayano, T., Buse, J. B., Edward, Y., Pilch, P. F., Bell, G. I., Seino, S.: Cloning and characterization of the major insulin sensitive glucose transporter expressed in human skeleton muscle and other insulin Sensitive Tissues. J. Biol. Chem., 264 : 7776-7779, 1989.

• 12) Carter, A. J., Jones, E. W.: The effect of the degree of diabetic control on the thromboxane synthesis in clotted whole blood. Thromb. Res., 41 : 137-141, 1986.
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• 12) Charles, S. T. H. II, Jones, P. M., Persaund, S. J., Howell, S. L.: A re-assessment of the role of protein kinase C in glucose-stimulated insulin secretion. Biochem. J., 246 : 489-493, 1987.

• 13) 仁木厚, 仁木初美, 玉川達雄, 仁木一郎 : インスリン分泌とCキナーゼ. 糖尿病学1986, 小坂樹徳他編, 診断と治療社, 東京, p1-18, 1986.

• 13) Caro, J. F., Ittop, O., Pories, W. J., Meelheim, D., Flickinger, E. G., Thomas, F., Jenquin, M., Silverman, J. F., Khazanie, P. G., Sinha, M. K.: Studies on the mechanism of insulin resistance in the liver from humans with non insulin-dependent diabetes. J. Clin. Invest. 78 : 249-258, 1986.

• 13) Press, M., Tamborlane, W. V., Sherwin, R. S.: Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes. N. Engl. J. Med., 310 : 810-815, 1984.
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• 13) Mazzone, T., Foster, D., Chait, A.: In vivo stimulation of low-density lipoprotein degradation by insulin. Diabetes, 33 : 333-338, 1984.
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• 13) Jones, D. B., Carter, R. D., Man, J. I.: Increased arachidonic acid level in diabetic platelets following improvement in diabetic control. Diabet. Metab., 12 : 65-67, 1986.

• 13) Kaestner, K. H., Christy, R. J., McLenithan, J. C., Braiterman, L. T., Cornelius, P., Pekala, P. H., Lane, M. D.: Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporters in mouse 3T3-L1 adiposytes. Proc. Natl. Acad. Sci., 86 : 3150-3154, 1989.

• 14) Kalofoutis, A., Lekakis, J.: Changes of platelet phospholipids in diabetes mellitus. Diabetologia, 21 : 540-543, 1981.
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• 14) Tamagawa, T., Niki, H., Niki, A.: Insulin release independent of a rise in cytosolic free Ca++ by forskolin and phorbol ester.: FEBS Lett., 183 : 430-432, 1985.

• 14) Tamborlane, W. V., Sherwin, R. S., Koivisto, V., Hendler, R., Genel, M., Felig, P.: Normalization of the growth hormone and catecholamine response to exercise in juvenile-onset diabetic subjects treated with a portable insulin infusion pump.Diabetes, 28 : 785-788, 1979.
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• 14) 岡芳知, 浅野知一郎 : Glucose transporter (糖輸送担体). Diabetes Journal, 16 : 97-106, 1988.

• 14) Witztum, J. L., Mahoney, E. M., Branks, M. J., Fisher, M., Elan, R., Steinberg, D.: Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activity. Diabetes, 31 : 283-291, 1982.

• 14) Kadowaki, T., Kasuga, M., Akanuma, Y., Egaki, Y., Takaku, F.: Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats. J. Biol. Chem, 259 : 14208-14216, 1984.

• 15) Burant, C. F., Treutelaar, M. K., Buse, M. G.: Diabetes-induced functional and structural changes in insulin receptors from rat skelton muscle. J. Clin. Invest., 77 : 260-270, 1986.

• 15) Wilson, P. W., Garrison, R. J., Castelli, W. P.: Prevalence of coronary heart disease in the Framingham off spring study. Role of lipoprotein cholesterol. AmJ. Cardiol., 46 : 649-665, 1980.

• 15) Jones, D. B., Haitus, B., Brown, E. G., Carter, R. G., Barker, K., Jelfs, R., Turner, R. C., Mann, J. I., Prescott, R. J.: Platelet aggregation in non-insulin-dependent diabetes is associated with platelet fatty acid. Diabetic Med., 3 : 52-55, 1986.

• 15) 堀田饒 : ポリオールおよびミオイノシトール代謝異常-糖尿病性合併症に果たすその役割. 糖尿病カレントレビュー1988, 坂本信夫他監修, 医歯薬出版, 東京, p239-267, 1988.

• 15) Malaisse, W. J., Sener, A., Herchuelz, M.: Insulinotropic effect of the tumor promoter 12-0-tetradecanoylphorbol 13-acetate in rat pancreatic islets. Cancer Res., 40 : 3827-3831, 1980.

• 15) 平田幸正 : 末端肥大症と糖尿病. 綜合臨牀, 33 : 1533-1537, 1984.

• 16) Malaisse, W. J., Lebrum, P., Herchuelz, A., Sener, A., Malaisse-Lagae, F.: Synergistic effect of a tumor-promoting phorbol ester and a hypoglycemic sulfonylurea upon insulin release. Endocrinology, 113 : 1870-1877, 1983.

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• 16) Davidson, M. B., Harris, M. D., Ziel, F. H., Rosenberg, C. S.: Suppression of sleep-induced growth hormone secretion by anticholinergic agent abolishes dawn phenomenon. Diabetes, 37 : 166-171, 1988.
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• 16) Malone, J. I., Knox, G., Benford, S., Tedesco, T. A.: Red cell sorbitol, An indicator of diabetic control. Diabetes, 29 : 861-864, 1980.
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• 17) 松崎宸 : 糖尿病における成長ホルモン病態 : 診断と治療, 73 : 1698-1700, 1985.

• 17) Giugliano, D., Misso, L., Tirelli, A., Coppola, L., DiPinto, P., Torella, R.: Platelet aggregation after strict metabolic control using the artificial pancreas (letter). Diabetologia, 23 : 545, 1982.

• 17) Mattews, E. K.: Electrophysiology of pancreatic islet-cells. The electrophysiology of the secretory cell. Poisner, A. M. et al. (eds), Elsevier, Amsterdam, p93, 1985.

• 17) 中井継彦 : 糖尿病におけるリポ蛋白代謝. 最新医学, 40 : 1475-1484, 1985.
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• 17) Kinoshita, J. H.: Mechanism initiating cataract formation. Proctor Lecture. Invest. Ophthalmol., 13 : 713-724, 1974.
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• 17) 片岡邦三, 西野素子 : 単純性肥満. 日本臨牀, 44 (夏季増刊) : 1011-1017, 1986
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• 18) Sharp, P. S., Fallon, T. J., Sandler, L., Joplin, G. F., Kohner, E. M.: Long-term follow-up patients who underwent yttrium-90 pituitary implantation for treatment of proliferative diabetic retinopathy. Diabetologia, 30 : 199-207, 1987.
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• 18) Kolterman, O. G., Insel, J., Saekow, M., Olefsky, J. M.: Mechanism of insulin resistance in human obesity, evidence for receptor and post receptor defects. J. Clin. Invest., 65 : 1272-1284, 1980.
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• 18) Henquin, J. C., Meissner, H. P.: Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cell. Experientia, 40 : 1043, 1984.
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• 18) Juhan, I., Buonocore, M., Jouve, R., Vague, P., Moulin, J. P., Vialettes, B.: Abnormalities of erythrocyte deformability and platelet aggregation in insulin-dependent diabetes corrected by insulin in vivo and in vitro. Lancet, i : 535-537, 1982.
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• 23) Patsh, J. R., Kunz, F., Sailer, S., Braunsteiner, H.: Studies on the degradation of lipoprotein-X Eur. J. Clin. Invest., 7 : 523-530, 1977.

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• 27) Kobori, S., Nakamura, N., Uzawa, H., Schichiri, M.: Influence of apolipoprotein E polymorphism on plasma lipid and apolipoprotein levels, and clinical characteristics of type III hyperlipoproteinemia due to apolipoprotein E phenotype E2/2 in Japan. Atherosclerosis, 69 : 81-88, 1988.

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• 47) 橋本俊彦, 石井英博, 梅田文夫, 名和田新, 麻生宣則, 山下司 : 家族性高プロインスリン血症が疑われた1例.: 糖尿病, 31 (Suppl.1) : 255, 1988.

• 48) 南條輝志男 : 異常インスリンの遺伝子. BIO medica, 4 : 241-246, 1988.

第III章 糖尿病の成因, 発症因子

P.97 掲載の参考文献

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• 20) Kobayashi, T., Sawano, S., Sugimoto, T., Itoh, T., Kosaka, K., Tanaka, T., Suwa, S.: Isletcell antibodies in IDDM and NIDDM in Japanese population. Tohoku J. Exp.Med., 141 (Suppl) : 271-274, 1983.

• 20) Crettaz, M., Jeanrenaud, B.: Postreceptor alteration in states of insulin resistance. Metabolism, 29 : 467-473, 1980.
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• 21) Modes, J. P., Rossini, A. A.: Diabetes and obesity. Clinical diabetes mellitus, Kozak, G. P. (eds), W. B. Saunders, Philadelphia, p.333, 1982.

• 21) 小林哲郎, 沢野真二, 伊藤徳治, 杉本忠夫, 田中敏章, 諏訪成三, 辻公美 : インスリン依存型およびインスリン非依存型糖尿病患者における抗ラ氏島抗体. 糖尿病, 25 : 1247-1248, 1982.

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• 22) Srikanta, S., Ganda, O. P., Jackson, R. A., Gleson, R. E., Kaldany, A., Garovoy, M. R., Milford, E. L., Carpenter, C. B., Soldner, J. S., Eisenbarth, G. S.: Type I diabetes mellitus in monozygotic twins : chronic progressive beta cell dysfunction. Ann. Intern. Med., 99 : 320-326, 1983.

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• 23) Lernmark, A., Freedman, Z. R., Hoffman, C., Rubenstein A. H., Steiner, D. F., Jackson, R. L., Witer, R. J., Traisman, H. S.: Islet-cell-surface antibodies in juvenile diabetes mellitus. N. Engl. J. Med., 299 : 375-380, 1978.

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• 24) Debertson, M. J., Scharff, J. E., Ginsberg-Feliner, F., Notkins, A. L.: Cytotoxic autoantibodies to beta cells in the serum of patients with insulin-dependent diabetes mellitus. N. Engl. J. Med., 303 : 1493-1498, 1980.

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• 25) Kissebach, A., Vydelingum, N., Murrey, R., Evans, D. J., Harty, H., Kalkhoff, R., Adams, P.: Relation of body fat distribution to metabolic complication of obesity. J. Clin. Endocrinol. Metab., 54 : 254-260, 1982.

• 26) Westermark, P., Grimelius, L., Polak, J. M.: Amyloid in polypeptide hormone-producing tumors. Lab. Invest., 37 : 212-215, 1977.
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• 26) Vardi, P., Ziegler, A. G., Mathews, J. H., Dib, S., Keller, R. J., Ricker, A. T., Wolfsdorf, J. I., Herskowitz, R. D., Rabizadek, A., Eisenbarth, G. S., Soeldner, J. S.: Concentration of insulin autoantibodies at onset of type 1 diabetes-Inverse long-linear correlation with age. Diabetes Care, 11 : 736-739, 1988.

• 27) Lukinius, A., Wilander, E., Westermark, G. T., Engstrom, U., Westermark, P.: Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets. Diabetologia, 32 : 240-244, 1989.

• 27) Karjakainen, J., Knip, M., Hydty, H., Leinikki, P., Ilonen, J., Kaar, M-L., A kerblom, H. K.: Relationship between serum insulin autoantibodies, islet cell antibodies and coxsackie-B4 and mumps virus-specific antibodies at the clinical manifestation of type 1 (insulin-dependent) diabetes. Diabetologia, 31 : 146-152, 1988.

• 28) Thivolet, C, Beaufrere, B., Betvel, H., Gebuhrer, L., Chatelain, P., Durand, A., Tourniaire, J.: Islet cell and insulin autoantibodies in subjects at high risk for development of type 1 (insulin-dependent) diabetes mellitus : the Lyon family study. Diabetologia, 31 : 741-746, 1988.

• 29) Irvine, W. J.: Classification of idiopathic diabetes. Lancet, i : 638-641, 1977.
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• 30) Ludvigsson, J., Afoke, O.: Seasonality of type 1 (insulin-dependent) diabetes mellitus : values of C-peptide, insulin antibodies and haemoglobih A1C show evidence of a more rapid loss of insulin secretion in epidemic patients. Diabetologia, 32 : 84-91, 1989.

• 31) 栗原宏子, 難波光義, 花房俊昭, 野中共平, 垂井清一郎 : ウイルス感染と糖尿病. 診断と治療, 73 : 1567-1570, 1985.

• 32) King, M. L., Shaikh, A., Bidwell, D.: Coxsackie-B-virus-specific IgM responses in children with insulin-dependent Guvenile-onset ; type I) diabetes mellitus. Lancet, i : 1397-1399, 1983.
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• 33) Yoon, J-W., Austin, M., Onodera, T., Notkins, A. L.: Virus-induced diabetes mellitus. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N. Engl. J. Med., 300 : 1173-1179, 1979.
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• 34) Gepts, W.: Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes, 14 : 619-633, 1965.
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• 35) 原満 : 糖尿病の病理. 診断と治療, 73 : 1602-1606, 1985.

• 36) Foster, D. W.: Diabetes mellitus. The metabolic basis of inherited disease, 7th ed., Stanbury, J. B. et al. (eds), McGraw-Hill, New York, p375-397, 1989.

• 37) 宮川潤一郎, 花房俊昭, 垂井清一郎 : IDDM-自己免疫とウイルス感染-. 治療, 70 : 5-10, 1988.

第IV章 糖尿病診断のポイント

P.117 掲載の参考文献

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• 42) 三家登喜夫, 里神永一, 曽和亮一, 栗山茂司, 岡井一彦, 森田一, 坂本健一, 近藤渓, 南條輝志男, 宮村敬 : 糖尿病患者におけるInsulin依存度の評価. 糖尿病, 28 : 713-719, 1985.

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• 56) 林康之 : 蛋白尿と尿沈渣検査法. 臨床病理, 49 (増刊) : 15-22, 1982.

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• 64) Hogemann, B., Voss, B., Altenwerth, F. J., Schneider, M., Rauterburg, J., Gerlach, U.: Concentration of 7S-collagen and laminin P1 in serum of patients with diabetes mellitus. Klin. Wochenschr., 64 : 382-385, 1986.

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• 71) 藤原哲司 : 神経伝導速度測定と臨床応用. 内科セミナー. 脳波・筋電図, 永井書店, 大阪, p256-272, 1982.

• 72) 景山茂, 清水光行, 笹生文雄, 斎藤宣彦, 種瀬富男, 阿部正和 : 糖尿病性自律神経障害の定量的分析に関する研究. 糖尿病, 22 : 627-634, 1979.

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• 74) 七里元亮, 鮴谷佳和 : インスリン療法-厳格な血糖制御と合併症の発症, 進展阻止. 現代医療, 19 : 2486-2494, 1987.

第V章 糖尿病治療の実際

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第VI章 治療における諸問題

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• 17) 佐中真由美, 大森安恵, 清水明美, 東桂子, 秋久理真, 小浜智子, 本田正志, 平田幸正, 亀山和子, 福田雅俊 : 糖尿病性網膜症と妊娠-光凝固療法の有用であった症例の検討-. 糖尿病, 30 : 595〜603, 1987.

• 17) 依田忠雄 : 小児NIDDMの治療. 糖尿病の療養指導1988, 日本糖尿病学会編, 診断と治療社, 東京, p190-195, 1988.

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• 19) Schmidt, M. I., Lin, Q. X., Gwynne, J. T., Jacobs, S.: Fasting early morning rise in peripheral insulin. Evidence of the dawn phenomenon in non-diabetes. Diabetes Care, 7 : 32-35, 1984.

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• 20) Alberti, K. G. M. M., Hockaday, T. D. R., Turner, R. C.: Small doses of intramuscular insulin in the treatment of diabetic coma. Lancet, ii : 515-522, 1973.

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• 21) Sonksen, P. H., Srivastava, M. C., Tompkins, C. V. Nabarro, J. D. N.: Growth hormone and cortisol responses to insulin in patients with diabetes mellitus. Lancet, ii : 155-159, 1972.

• 21) Spinas, G, A., Bock, A., Keller, U.: Reduced postprandial hyperglycemia after subcutaneous injection of a somatostatin-analogue (SMS 201-995) in insulin-dependent diabetes mellitus. Diabetes Care, 8 : 429-435, 1985.
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• 22) 七里元亮, 河盛隆造, 鮴谷佳和, 村田貞史, 菊池幹雄, 山崎義光, 野村誠, 新居貞雄, 阿部裕 : 人工膵β細胞による糖尿病性昏睡. ケトーシスの治療-インスリン少量持続注入療法との比較-, 糖尿病, 23 : 235-244, 1980.

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• 26) Franklin, B., Liu, J., Ginsberg-Fellner, F.: Cerebral edema and ophthalmoplegia reversed by mannitol in a new case of insulin-dependent diabetes mellitus. Pediatrics, 69 : 87-90, 1982.

• 27) Carroll, P., Matz, R.: Adult respiratory distress syndrome complicating severely uncontrolled diabetes mellitus : Report of nine cases and a review of the literature. Diabetes Care, 5 : 574-580, 1982.

第VII章 合併症とその管理

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• 5) Thomas, P. K., Eliasson, S. G.: Diabetic neuropathy. Peripheral Neuropathy, Vol.2, Dyck, P. J. et al. (eds). W. B. Saunders Co., Philadelphia, p1773-1810, 1984.

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• 6) Kador, P. F., Kinoshita, J. H.: Role of aldose reductase in the development of diabetesassociated complications. Am. J. Med., 79. (Suppl.5A) : 8-12, 1985.

• 6) Newrick, P. G., Boulton, A. J. M., Ward, J. D.: The distribution of diabetic neuropathy in a British clinic population. Diab. Res. Clin. Prac., 2 : 263-268, 1986.

• 6) 福田雅俊 : 糖尿病性眼合併症の早期発見法. 日本臨牀, 44 (夏季増刊) : 798-803, 1986.
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• 7) 布井清秀, 吉田冨士雄, 藤島正敏 : 糖尿病における脳血管障害予防プログラム. 綜合臨牀, 37 : 2453-2457. 1988.

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• 7) Levin, M. E.: The diabetic foot : pathophysiology, evaluation, and treatment. Diabetic Foot. 4th ed. Levin, W. M., et al. (eds), Mosby, St. Louis, MO. p1-50, 1987.

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• 8) Siitonen, O., Uusitupa, M., Pydrala, K., Voutilainen, E., Lansimies, E.: Peripheral arterial disease and its relationship to cardiovascular risk factors and coronary heart disease in newly diagnosed non-insulin-dependent diabetes. Acta Med. Scand., 220 : 205-212, 1986.

• 8) Clements, R. S., Bell, D. S. H.: Complication of diabetes : Prevalence, detection, current treatment, and prognosis. Am. J. Med., 79 (Suppl.5A) : 2-7, 1985.

• 8) Brownlee, M., Cerami, A., Vlassara, H.: Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N. Engl. J. Med. 318 : 1315-1321, 1988.
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• 8) Boulton, A. J. M., Scarpello J. H. B., Ward, J. D.: Venous oxygenation in the diabetic neuropathic foot : evidence of arteriovenous shunting? Diabetologia 22 : 6-8, 1982.

• 8) 松田正尚 : 肺結核と糖尿病. 結核, 57 : 659-663, 1982.

• 8) Winegrad, A. I.: Does a common mechanism induce the diverse complications of diabetes? (Banting lecture 1986). Diabetes, 36 : 396-406, 1987.
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• 9) Edmonds, M. E.: The Neuropathic Foot in Diabetes, Part 1 : Blood Flow. Diabetic Med., 3 : 111-115, 1986.

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• 9) 古川隆一 : 糖尿病と腎. Common Disease Series 1 : 糖尿病, 高久史麿監修・赤沼安夫編, 南江堂, 東京, p215-224, 1988.

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• 9) Boulton, A. J. M., Drury, J., Clark, B., Ward, J. D.: Continuous subcutaneous insulin infusion in the management of painful diabetic neuropathy. Diabetes Care, 5 : 386-390, 1982.

• 9) 堀田饒 : ポリオールおよびミオイノシトール代謝異常-糖尿病性合併症に果たすその役割. 糖尿病カレントレビュー1988, 坂本信夫他監修, 医歯薬出版, 東京, p239-267, 1988.

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• 10) Edmonds, M. E., Nicolaides, K. H., Watkins, P. J.: Autonomic Neuropathy and diabetic foot ulceration. Diabetic Med., 3 : 56-59, 1986.
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• 10) 福田雅俊 : 糖尿病性網膜症の病態とその対策. 糖尿病学の進歩 (第22集), 日本糖尿病学会編, 診断と治療社, 東京, p51-54, 1988.

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• 11) Halushka, P. V., Mayfield, R., Colwell, J. A.: Insulin and arachidonic acid metabolism in diabetes mellitus. Metabolism, 34 (Suppl.1) : 32-36, 1985.

• 11) Edmonds, M. E., Blundell, M. P., Morris. H. E., Thomas, E. M., Cotton, L. T., Watkins, P. J., : The diabetic foot : impact of a foot clinic. Quat. J. Med. 232 : 763-771, 1986.

• 11) 原茂子, 三村信英 : 二次糸球体病変-糖尿病-. 日本臨牀, 46 : 1381-1385, 1988.

• 11) Mogensen, C. E., Christensen, C. K., Vittinghus, E.: The stages in diabetic renal disease : With emphasis on the stage of incipient diabetic nephropathy. Diabetes, 32 (Suppl.2) : 64-78, 1983.

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• 12) Porta, M., Selva, M. L., Molinatti, P., Molinatti, G. M.: Endothelial cell function in diabetic microangiopathy (Review article). Diabetologia, 30 : 601-609, 1987.

• 12) Yano, T., Nakamura, N., Uzawa, H., Kobori, S., Maruyama, H., Takeda, H., Kiyota, S., Fukushima, H., Ichinose, K., Migiyama, T., Iseki, T., Wakamatsu, T., Shimada, M.: Multiple regression analysis of sixteen risk factors including serum apolipoproteins in angiographically documented coronary artery disease. Jap. Circ. J., 51 : 383-394, 1987.

• 12) 渡辺敏郎, 河津捷二 : 糖尿病性腎症の発症機序と臨床化学的早期認知. 糖尿病学1989, 小坂樹徳他編, 診断と治療社, 東京, p267-296, 1989.

• 12) Gibbons, G. W., Eiliopoulos, G. M.: Infection of the diabetic foot. In Management of Diabetic Foot Problems. Kozak, G. P. et al. (eds), PA, Saunders, Philadelphia, p97-102, 1984.

• 12) 坂口弘 : 糖尿病性腎症-病理学. 日本臨牀, 44 (夏季増刊) : 672-677, 1986.
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• 12) 繁田幸男 : グリコシレーションと糖尿病合併症. 糖尿病学の進歩 (第21集), 日本糖尿病学会編, 診断と治療社, 東京, p151-159, 1987.

• 13) Young, R. J., Macintyre, C. C. A., Martyn, C, N., Prescott, R. J., Ewing, D. J., Smith, A. F., Viberti G., Clarke, B. F.: Progression of subclinical polyneuropathy in young patients with type I (insulin-dependent) diabetes : associations with glyCaemic control and microangiopathy (microvascular complications). Diabetologia, 29 : 156-161, 1986.
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• 13) Mogensen, C. E.: Management of diabetic renal involvement and disease. Lancet, i : 867-870, 1988.
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• 13) 寺田秀夫 : 血小板異常 (糖尿病にみられる各種病態). 日本臨牀, 44 (夏季増刊) : 358-362, 1986.

• 13) Brownlee, M., Cerami, A., Vlassara, H.: Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N. Engl. J. Med., 318 : 1315-1321, 1988.
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• 13) Clements, R. S.: Diabetic neuropathy : new concepts of its etiology. Diabetes, 28 : 604-611, 1979.
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• 13) 山崎昇 : 脂質代謝と虚血性心疾患. 日本臨牀, 45 : 1112-1122, 1987.
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• 14) Nelson, R. G., Gohdes, D. M., Everhart, J. E., Hartner, J. A., Zwemer, F. L., Pettitt, D. J., Knowler, W. C., : Lower-extremity amputation in NIDDM : 12-year follow-up study in Pima Indians. Diabetes Care, 11 : 8-16, 1988.

• 14) 佐々木陽 : 糖尿病合併症のRisk Factor. 内科, 64 : 14-17, 1989.

• 14) 寺田秀夫 : 凝固系, 線溶系異常 (糖尿病にみられる各種病態). 日本臨牀, 44 (夏季増刊) : 363-366, 1986.

• 14) 豊田隆謙, 八木橋操六 : 糖尿病性神経障害の成因について. 糖尿病学1988, 小坂樹徳他編, 診断と治療社, 東京, p272-288, 1988.

• 14) Hostetter, T. H., Rennke, H. G., Brenner, B. M.: The case for intrarenal hypertension and progression of diabetic and other glomerulopathies. Am. J. Med., 72 : 375-380, 1982.
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• 14) Greene, D. A.: Metabolic abnormalities in diabetic peripheral nerve : relation to impaired function. Metabolism, 32 : 118-123, 1983.
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• 14) 吉川隆一 : 蛋白のグリコシレーション. 糖尿病カレントレビュー, 坂本信夫他監修, 医歯薬出版, 東京, p239-267, 1988.

• 15) 北村啓次郎 : 糖尿病と皮膚. Common Disease Series 1 : 糖尿病, 高久史麿監修・赤沼安夫編, 南江堂, 東京, p236-245, 1988.

• 15) Bessman, A. N., Page, J., Thomas, L. J.: In vivo pH of induced soft-tissue abscesses in diabetic and nondiabetic mice. Diabetes, 38 : 659-662, 1989.
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• 15) Zatz, R., Brenner, B. M.: Pathogenesis of diabetic microangiopathy : The hemodynamic view. Am. J. Med., 80 : 443-453, 1986.
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• 15) Colwell, J. A., Winocour, P. D., Lopes-Virella, M. F., Halushka, P. V.: New concepts about the pathogenesis of atherosclerosis in diabetes mellitus. Am. J. Med., 75 (5B) 67-80, 1983.

• 15) Hale, P. J., Nattrass, M., Silverman, S. H., Sennit, C., Perkins, C. M., Uden, A., Sundkivst, G.: Peripheral nerve concentrations of glucose, fructose, sorbitol and myoinositol in diabetic and non-diabetic patients. Diabetologia, 30 : 464-467, 1987.
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• 15) 老籾宗忠, 井垣直哉 : Glycationと糖尿病性合併症. 内科, 64 : 34-38, 1989.

• 15) 井藤英喜 : プロスタノイドと糖尿病合併症. 内科, 64 : 25-29, 1989.

• 16) Greene, D. A., Lattimer, S., Ulbrecht, J., Carroll, P.: Glucose-induced alterations in nerve metabolism : current perspective on the pathogenesis of diabetic neuropathy and future directions for research and therapy. Diabetes Care, 8 : 290-299, 1985.
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• 16) Zatz, R., Dunn, B. R., Meyer, T. W., Anderson, S., Rennke, H. G., Brenner, B. M.: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J. Clin. Invest., 77 : 1925-1930, 1986.
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• 16) LoGerfo, F. W., Coffman, J. D., : Vascular and microvascular disease of the foot in diabetes : implications for foot care. N. Engl. J. Med., 311 : 1615-1619, 1984.

• 16) Halushka, P. V., Mayfield, R., Colwell, J. A.: Insulin and arachidonic acid metabolism in diabetes mellitus. Metabolism, 34 (Suppl.1) : 32-36, 1985.

• 16) Ganda, O. P.: Pathogenesis of macrovascular disease including the influence of lipids. Joslin's Diabetes Mellitus (12th ed.), Marble, A. et al. (eds), Lea & Febiger, Philadelphia, p 217-250, 1985.

• 16) 井上勝平 : 感染をめぐる皮膚疾患の種類・予防・治療 (糖尿病-多発性感染その特徴と対策). プラクティス, 5 : 336-339, 1988.

• 17) 松井瑞夫 : 糖尿病性網膜症とは. プラクティス, 3 : 385-389, 1986.

• 17) Porta, M., Selva, M. L., Molinatti, P., Molinatti, G. M.: Endothelial cell function in diabetic microangiopathy (Review article). Diabetologia, 30 : 601-609, 1987.

• 17) Lithner, F., Tornblom, N.: Gangrene localized to the feet in diabetic patients. Acta Med. Scand., 215 : 75-79, 1984.

• 17) 宇高不可思, 佐古伊康, 亀山正邦 : 脳血管障害. 日本臨牀, 44 (夏季増刊) : 651-658, 1986.
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• 17) Ortola, F. V., Ballermann, B. J., Anderson, S., Mendez, R. E., Brenner, B. M.: Elevated plasma atrial natriuretic peptide levels in diabetic rats : Potential mediator of hyperfiltration. J. Clin. Invest., 80 : 670-674, 1987.
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• 17) 後藤由夫, 及川真一 : 高血糖. 動脈硬化症の新しい診断と治療, 五島雄一郎他編, 医薬ジャーナル社, 大阪, p119-132, 1985.

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• 18) Howard, B. V.: Lipoprotein metabolism in diabetes mellitus (minireview). J. Lipid Res., 28 : 613-628, 1987.

• 18) 寺田秀夫 : 血小板異常 (糖尿病にみられる各種病態). 日本臨牀, 44 (夏季増刊) : 357-362, 1986.

• 18) Greene, D. A.: A sodium-pump defect in diabetic peripheral nerve corrected by sorbinil administration : relationship to myo-inositol metabolism and nerve conduction slowing. Metabolism, 35 (Suppl.1) : 60-65, 1986.

• 18) Schambelan, M., Blake, S.: Increased protaglandin production by glomeruli isolated from rats with streptozotocin induced diabetes mellitus. J. Clin. Invest., 75 : 404-412, 1985.

• 18) Mueller, M. J., Diamond, J. E., Sinacore, D. R., Delitto, A., Blair, V. P., Drury, D. A., Rose, S. J.: Total contact casting in treatment of diabetic planter ulcers. Controlled clinical trial. Diabetes Care, 112 : 384-388, 1989.

• 18) 平山章 : 眼科領域の合併症-病理学 (糖尿病性合併症). 日本臨牀, 44 (夏季増刊) : 785-789, 1986.

• 19) Greene, D. A., Lattimer, S. A.: Impaired rat sciatic nerve sodium-potassium adenosine triphosphate in acute streptozotocin diabetes and its correction by dietary myo-inositol supplementation. J. Clin. Invest., 72 : 1058-1063, 1983.

• 19) 寺田秀夫 : 凝固系, 線溶系異常 (糖尿病にみられる各種病態). 日本臨牀, 44 (夏季増刊) : 363-366, 1986.

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• 19) Sinacore, D. R., Mueller, M. J., Diamond, J. E., Blair, V. P., Drury, D. A., Rose, S. J.: Diabetic neuropathic planter ulcers treated by total contact casting. Phys. Ther., 67 : 1543-1549, 1987.

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第VIII章 患者へのアプローチ

P.451 掲載の参考文献

• 1) Diabetes Mellitus, Report of a WHO Study Group, Technical Report Series 727, WHO, Geneva, 1985.

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• 2) 羽倉稜子 : Joslin Diabetes Centerと患者教育. 糖尿病学1983, 小坂樹徳編, 診断と治療社, 東京, p290-311, 1983.

• 2) 三村悟郎 : 小児サマーキャンプについて. 糖尿病の療養指導1978, 日本糖尿病学会編, 診断と治療社, 東京, p78-88, 1978.

• 3) 堀内光 : 治療計画のプログラムと教育入院. 日本臨牀, 44 (夏季増刊) : 385-393, 1986
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• 4) 丸山博 : わが国における小児糖尿病サマーキャンプ. ホルモンと臨床, 30 : 975-979, 1982.

• 4) Schnatz, J. D.: Patient education and supporting services. Diabetes Mellitus : Problems in Managerent, Schnatz, J. D. (ed), Addison-Wesley, California, p63, 1982.