書籍詳細

[1] 慢性肝疾患からの肝癌発癌

P.25 掲載の参考文献

• 1) The Liver Cancer Study Group of Japan. Primary liver cancer in Japan:Clinicopathological features and results of surgical treatment. Ann Surg 211:277-287, 1990

• 2) 池田健次, 熊田博光:肝硬変の経過と予後. 日本臨床 52:63-68, 1993

• 3) Prince AM, Szmuness W, Michon J, et al:A case-control study of the association between primary liver cancer and hepatitis B infection in Senegal. Int J Cancer 16:376-383, 1975

• 4) Austin H, Delzell E, Grufferman S, et al:A case-control study of hepatocellular carcinoma and the hepatitis B virus, cigarette smoking, and alcohol consumption. Cancer Res 46:962-966, 1985

P.26 掲載の参考文献

• 5) Obata K, Hayashi N, Motoike Y:A prospective study on the development of hepatocellular carcinoma from liver cirrhosis with persistent hepatitis B virus infection. Int J Cancer 25:741-747, 1980

• 6) Choo QL, Kuo G, Weiner AJ, et al:Isolation of a cDNA clone derived from a non-A, non-B viral hepatitis genome. Science 255:359-362, 1989

• 7) Bruix J, Calvet X, Costa J, et al:Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet 2:1004-1006, 1989
  pubmed

• 8) Sakamoto M, Hirohashi S, Tsuda H, et al:Increasing incidence of hepatocellular carcinoma possibly associated with non-A, non-B hepatitis in Japan, disclosed by hepatitis B virus DNA analysis of surgically resected cases. Cancer Res 48:7294-7297, 1988
  pubmed

• 9) Ikeda K, Saitoh S, Koida I, et al:A multivariate analysis of risk factors for hepatocellular carcinogenesis:A prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 18:47-53, 1993
  pubmed

• 10) Kaplan EL, Meier P:Nonparametric estimation for incomplete observation. J Am Stat Assoc 53:457-481, 1958

• 11) Villa E, Baldini GM, Pasquinelli C, et al:Risk factors for hepatocellular carcinoma in Italy:Male sex, hepatitis B virus, non-A non-B infection, and alcohol. Cancer 62:611-615, 1988

• 12) Cox DR:Regression models and life tables. J R Stat Soc 34:248-275, 1972

• 13) 佐藤辰夫, 迎 英明, 高原 耕:肝硬変を伴わない原発性肝癌に関する一考察-Hepatitis B surface antigen carrier の非硬変肝に発生したa-fetoprotein 陰性原発性肝癌の1剖検例を中心として-. 肝臓 20:63-69, 1979

• 14) Okuda K, Nakashima T, Sakamoto K, et al:Hepatocellular carcinoma arising in non-cirrhotic and highly cirrhosis liver. Cancer 49:450-455, 1982

• 15) Lin DY, Liaw YF, Chu CM:Hepatocellular carcinoma in noncirrhotic patients-A laparoscopic study of 92 cases in Taiwan. Cancer 54:1466-1468, 1984
  pubmed

• 16) 池田健次, 熊田博光, 荒瀬康司, 他:肝硬変非合併肝細胞癌の検討-特に, 早期発見の問題について. 肝臓 27:1424-1430, 1986

[2] 小型肝細胞癌の診断

P.46 掲載の参考文献

• 1) Ikeda K, Saitoh S, Koida I, et al:A multivariate analysis of risk factors for hepatocellular carcinogenesis:A prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 18:47-53, 1993
  pubmed

• 2) The Liver Cancer Study Group of Japan:Primary liver cancer in Japan:Clinicopathological features and results of surgical treatment. Ann Surg 211:277-287, 1990

• 3) Arakawa M, Sugihara S, Kenmochi K, et al:Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver:observation in five cases. Gastroenterology 91:198-208, 1986

• 4) Takayama T, Makuuchi M, Hirohashi S, et al:Malignant transformation of adenomatous hyperplasia to hepatocellular carcinoma. Lancet 336:1150-1153, 1990
  pubmed

• 5) Hirooka N, et al:Microscopic incipient hepatocellular carcinoma found incidentally in a routine liver biopsy specimen. Hepatology 12:291-294, 1990

• 6) 池田健次, 熊田博光, 荒瀬康司, 他:肝硬変非合併肝細胞癌の検討-特に早期発見の問題について-. 肝臓 27:1424-1430, 1986

• 7) 斉藤 聡, 池田健次, 鯉田 勲, 他:アビジン‐ビオチン法を用いた高感度PIVKA-III測定による肝細胞癌早期診断の試み. 肝臓 34:591-596, 1993

• 8) 斉藤 聡, 池田健次, 鯉田 勲, 他:肝癌のスクリーニング検査としての腹部超音波 (US) とX線CT (CT) の診断能力と限界. 消化器科 17:505-510, 1992

• 9) Breedis C, Young G:The blood supply of neoplasms in the liver. Am J Pathol 30:969-985, 1954
  pubmed

• 10) Okuda K, Obata H, Jinnouchi S, et al:Angiographic assessment of gross anatomy of hepatocellular carcinoma:comparison of celiac angiograms and liver pathology in 100 cases. Radiology 123:21-29, 1977
  pubmed

• 11) Cooper JN:Imaging and hepatocellular carcinoma. Gastroenterol Clin North Am 16:591-602, 1987
  pubmed

• 12) Ikeda K, Saitoh S, Koida I, et al:Diagnostic sensitivity in small hepatocellular carcinoma of 2cm or less in diameter:Comparisons of digital subtraction angiography, computed tomographic-arterioportography, and enhanced-ultrasonography. Hepatology, 1994

P.47 掲載の参考文献

• 13) Edmondson HA, Steiner PE:Primary carcinoma of the liver. A study of 100 cases among 48,900 necropsies. Cancer 7:462-503, 1954
  pubmed

• 14) Matsui O, Kadoya M, Kamemiya T, et al:Work in progress:Dynamic sequential computed tomography during portography in the detection of hepatic neoplasms. Radiology 146:721-727, 1982

• 15) Matsuda Y, Yabuuchi I:Hepatic tumors:US contrast enhancement with CO2 microbubbles. Radiology 161:701-705, 1986
  pubmed

• 16) Ikeda K, Saitoh S, Koida I, et al:Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography. Hepatology 17:1003-1007, 1993
  pubmed

• 17) 真島康雄, 藤本隆史, 岩井一郎, 他:新しいエコー下細径針組織生検法による肝細胞癌の診断とその意義. 肝臓 29:629-636, 1988

• 18) 日本肝癌研究会:臨床. 病理原発性肝癌取扱い規約 (第3版). 金原出版, 東京, 1992

• 19) 神代正道:小さな肝癌の病理形態学的特徴. 病理と臨床 6:278-283, 1988

• 20) Kondo F, Wada K, Nagato Y, et al:Biopsy diagnosis of well-differentiated hepatocellular carcinoma based on new morphological criteria. Hepatology 9:751-755, 1989
  pubmed

[3] 肝癌の外科切除と再発

P.65 掲載の参考文献

• 1) Okuda K, Obata H, Nakajima Y, et al:Prognosis of primary hepatocellular carcinoma. Hepatology 4:3-6, 1984
  pubmed

• 2) Franco D, Smadja C, Meakins JL, et al:Improved early results of elective hepatic resection for liver tumors:one hundred consecutive hepatectomies in cirrhotic and noncirrhotic patients. Arch Surg 124:1033-1037, 1989
  pubmed

• 3) Nagao T, Inoue S, Yoshimi F, et al:Postoperative recurrence of hepatocellular carcinoma. Ann Surg 211:28-33, 1990
  pubmed

• 4) Ikeda K, Saitoh S, Tsubota A, et al:Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma. Cancer 71:19-25, 1993

• 5) Yamanaka N, Okamoto E, Toyosaka A, et al:Prognostic factors after hepatectomy for hepatocellular carcinomas:A univariate and multivariate analysis. Cancer 65:1104-1110, 1990
  pubmed

P.66 掲載の参考文献

• 6) Edmondson HA, Steiner PE:Primary carcinoma of the liver:a study of 100 cases among 48,900 necropsies. Cancer 7:462-503, 1954
  pubmed

• 7) 日本肝癌研究会:臨床. 病理, 原発性肝癌取扱い規約, 金原出版, 1987

• 8) Hedley D, Friedlander ML, Taylor IW:Method for analysis of cellular DNA contents of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem 31:1333-1335, 1983
  pubmed

• 9) Gerdes J, Lemke H, Baisch H, et al:Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133:1710-1715, 1984
  pubmed

• 10) Nagasue N, Yukaya H, Ogawa Y, et al:Second hepatic resection for reccurent hepatocellular carcinoma. Br J Surg 73:434-438, 1986

• 11) Lange JF, Leese T, Castaing D, et al:Repeat hepatectomy for recurrent malignant tumors of the liver. Surg Gynecol Obstet 169:119-126, 1989
  pubmed

• 12) Nakao N, Kamino K, Miura K, et al:Recurrent hepatocellular carcinoma after partial hepatectomy:value of treatment with transcatheter arterial chemoembolization. AJR 156:1177-1179, 1991

• 13) Ikeda K, Kumada H, Saitoh S, et al:Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma:an analysis by Cox proportional hazard model. Cancer 68:2150-2154, 1991
  pubmed

[4] 肝細胞癌に対するエタノール局注療法

P.83 掲載の参考文献

• 1) 杉浦信之, 高良健司, 大藤正雄, 他:超音波映像下経皮的腫瘍内エタノール注入による小肝細胞癌の治療. 肝臓 26:920, 1983

• 2) Tanaka M, Fujimoto T, Majima Y, et al:Percutaneous ultrasonographically guided ethanol injection therapy for small hepatocellular carcinoma. Proceedings of the Fourth Meeting of the World Federation for Ultrasound in Medicine and Biology, 102, 1985

• 3) 清水元茂, 鵜浦雅志, 小林健一, 他:超音波ガイド下エタノール注入療法を施行した腫瘍径 7〜8cm の肝細胞癌の2例について. 肝臓 30:811-819, 1989

• 4) 真島康雄, 藤本隆史, 谷川久一:細小肝癌の治療法-その適応と予後-, エタノール局注療法を中心に. 臨床消化器内科 7:531-536, 1992

• 5) 大西久仁彦, 陳 信義, 伊藤 進:腫瘍径 1〜3cm の肝細胞癌に対する経皮的酢酸注入療法. 肝臓 34:504-516, 1993

• 6) 日本肝癌研究会:肝癌治療直接効果判定基準. 肝臓 35:194-205, 1994

• 7) 里井重仁, 森本 晋, 込山賢次, 他:肝動脈塞栓術とエタノール局注療法の併用により著明な腫瘍壊死効果をみた進行肝細胞癌の1例. 日消誌 85:1694-1698, 1988

• 8) 田中克明, 岡崎 博, 中村三郎, 他:進行肝細胞癌に対する肝動脈塞栓術と超音波下エタノール局注療法の併用効果の検討. 肝臓 31:944-951, 1990

• 9) 池田健次, 斉藤 聡, 荒瀬康司, 他:肝動脈塞栓術施行肝細胞癌にエタノール注入療法を併用する臨床的意義と治療効果-特に, 多発例に対する有用性の検討-. 日癌治 26:58-65, 1991

[5] 血管造影と肝動脈塞栓術の方法と適応

P.95 掲載の参考文献

• 1) The Liver Cancer Study Group of Japan:Primary liver cancer in Japan. Cancer 60:1400-1411, 1987

• 2) The Liver Cancer Study Group of Japan:Primary liver cancer in Japan:Clinicopathological features and results of surgical treatment. Ann Surg 211:277-287, 1990

• 3) Wheeler PG, Melia W, Dubbins P, et al:Non-operative arterial embolization in primary liver tumours. Br Med J 2:242-244, 1979
  pubmed

• 4) Chuang VP, Wallace S:Current status of transcatheter management of neoplasms. Cardiovasc Intervent Radiol 3:256-267, 1980
  pubmed

• 5) Yamada R, Sato M, Kawabata M, et al:Hepatic artery embolization in 120 patients with unresectable hepatoma. Radiology 148:397-401, 1983
  pubmed

• 6) Lin DY, Liaw YF, Lee TY, et al:Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma:A randomized controlled trial. Gastroenterology 94:453-456, 1988
  pubmed

• 7) Ikeda K, Kumada H, Saitoh S, et al:Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma:An analysis by Cox proportional hazard model. Cancer 68:2150-2154, 1991
  pubmed

• 8) Seldinger SI:Catheter replacement of the needle in percutaneous arteriography. Acta Radiol 39:368-376, 1952

• 9) 日本肝癌研究会:臨床. 病理, 肝癌取り扱い規約, 東京, 金原出版, 1987

• 10) Breedis C, Young G:The blood supply of neoplasms in the liver. Am J Pathol 30:969-985, 1954
  pubmed

• 11) Luessenhop AJ, Spence WT:Artificial embolization of cerebral arteries. JAMA 172:1153-1155, 1960

• 12) Doppman JL:Obliteration of spinal-cord arteriovenous malformation by percutaneous embolization. Lancet 1:477, 1968
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• 13) Lang EK:Superselective arterial catheterization of tumors of the urogenital tract. J Urol 104:16-25, 1970
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• 14) 打田日出夫:Interventional Angiography, とくに腹部領域におけるTranscatheter embolizationによる治療. 日独医報 24:475-479, 1979

• 15) 打田日出夫, 中村仁信, 吉岡寛康, 他:Transcatheter Embolizationによる大量消化管出血の治療. 日独医報 24:519-528, 1979

• 16) Doyon D, Mouzon A, Jourde AM, et al:L'embolisation arterielle hepatique dans les tumeurs malignes du foie. Ann Radiol 17:593-603, 1974
  pubmed

• 17) Goldstein HM, Wallace S, Anderson JH, et al:Transcatheter occlusion of abdominal tumors. Radiology 120:1033-1034, 1976

P.96 掲載の参考文献

• 18) Shermeta DW, Golladay ES, White RI Jr:Preoperative occlusion of the hepatic artery with isobutyl 2-cyanoacrylate for resection of the "unresectable" hepatic tumor. Surgery 83:319-322, 1978
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• 19) 山田龍作, 中塚春樹, 中村健治, 他:各種悪性腫瘍に対するtranscatheter arterial embolizationの経験. 脈管学 18:563-571, 1978

• 20) 山田龍作, 中塚春樹, 中村健治, 他:肝細胞癌に対するtranscatheter arterial embolization therapy-15例の経験-. 肝臓 20:595-603, 1979

• 21) 市田隆文, 小島 隆, 中野 護, 他:肝細胞癌に対するTranscatheter Arterial Embolization療法の臨床病理学的検討. 肝臓 22:1264-1275, 1981

• 22) 大石 元, 大上庄一, 居出弘一, 他:肝細胞癌に対する肝動脈塞栓術後のCTによる効果判定. 肝臓 22:1569-1576, 1981

• 23) Okamura J, Horikawa S, Fujiyama T, et al:An appraisal of transcatheter arterial embolization combined with transcatheter arterial infusion of chemotherapeutic agent for hepatic maligriancies. World J Surg 6:352-357, 1982
  pubmed

• 24) 池田健次, 小宅映士, 熊田博光, 他:肝癌に対するtranscatheter arterial embolization therapyの評価. 日消誌 81:249-253, 1984

• 25) 岡本英三, 田中信孝, 山中若樹, 他:切除不能の原発性肝細胞癌に対する肝動脈結紮術60例の検討. 肝臓 23:1315-1325, 1982

• 26) Michels NA:Collateral artery pathways to the liver after ligation of the hepatic artery and removal of the coeliac axis. Cancer 6:708-724, 1953

• 27) Sprayregen S:Parasitic blood supply of neoplasms. Mechanisms and significance. Radiology 106:529-535, 1973
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• 28) Charnsangavej C, Chuang VP, Wallace S, et al:Angiographic classification of hepatic arterial collaterals. Radiology 144:485-494, 1982
  pubmed

• 29) 松尾尚樹, 大石 元, 仲川房幸, 他:肝動脈塞栓術 (TAE) による長期生存肝細胞癌の検討. 日消誌 83:1176-1186, 1986

• 30) Chuang VP, Wallace S, Soo CS, et al:Therapeutic ivalon embolization of hepatic tumors. AJR 138:289-294, 1982
  pubmed

• 31) 打田日出夫, 大石 元:Interventional Angiography:Embolizationの基本事項. 治療 68:699-702, 1986

• 32) Hirai K, Kawazoe Y, Yamashita K, et al:Arterial chemotherapy and transcatheter arterial embolization therapy for non-resectable hepatocellular carcinoma. Cancer Chemother Pharmacol 23:S37-S41, 1989
  pubmed

• 33) Venook AP, Stagg RJ, Lewis BJ, et al:Chemoembolization for hepatocellular carcinoma. J Clin Oncol 8:1108-1114, 1990
  pubmed

• 34) 津田正洋, 山田龍作, 佐藤守男, 他:抗癌剤併用肝動脈塞栓療法 (TAE) における抗癌剤の動態の検討.-targeting chemotherapy としての塞栓化学療法-. 日本医放会誌 50:504-511, 1990

P.97 掲載の参考文献

• 35) 徳山勝之, 神野健二, 湯本康弘, 他:油性制癌剤と肝動脈塞栓術の併用療法-切除小肝癌2例の臨床病理学的検討-. 癌の臨床 8:955-964, 1984

• 36) 村田敏彦, 木下 豊, 松尾尚樹, 他:肝細胞癌に対する肝動脈塞栓術後のAFP値の推移. 肝臓 26:323-334, 1985

• 37) Sasaki Y, Imaoka S, Kasugai H, et al:A new approach to chemoembolization therapy for hepatoma using ethiodized oil, cisplatin, and gelatin sponge. Cancer 60:1194-1203, 1987
  pubmed

• 38) 井上敦雄, 児島淳之介, 春日井博志, 他:肝細胞癌に対するリピオドール, シスプラチン, エトポシドを用いた肝動注化学塞栓療法. 日癌治 25:2788-2793, 1990

• 39) 加藤哲郎, 根本良介, 森 久, 他:各種進行癌に対するMMCマイクロカプセル動注の試み. 日癌治 15:353-361, 1980

• 40) Tedler H, Nilsson B, Johnsson K, et al:Hepatic arterial administration of doxorubicin with or without degradable starch microspheres:a pharmacokinetic study in man. In:Anthracyline and cancer therapy, Hansen H (ed.) Excepta Medica, 166-174, 1983

• 41) Pfeifle CE, Howell SB, Bookstein JJ:Pilot study of intraarterial floxuridine, mitomycin and doxonlbicin in combination with degradable starch microspheres to treat primary and metastatic tumor of the liver. Cancer Drug Delivery 2:305-311, 1985

• 42) 高安幸生, 横山英世, 竹原満登里, 他:肝癌のdegradable starch microspheres併用間歓的化学塞栓療法. 癌と化学療法 17:1715-1720, 1990

• 43) Greenfield AJ, Athanasoulis CA, et al:Transcatheter embolization:Prevention of embolic reflux using balloon catheters. AJR 131:651-655, 1978
  pubmed

• 44) 松尾賢二, 鈴木 誠, 木村一夫, 他:Balloonカテーテルを応用した超選択的血管造影について. 脈管学 21:401-407, 1981

• 45) 大井博道, 山本忠司, 沢井ユカ, 他:肝細胞癌に対する区域性肝動脈-門脈同時塞栓化学療法 (セメント療法) の治療成績. 癌と化学療法 16:(part II):2853-2857, 1989

• 46) Uchida H, Ohishi H, Matsuo N, et al:Transcatheter hepatic segmental arterial embolization using Lipiodol mixed with an anticancer drug and Gelfoam particles for hepatocellular carcinoma. Cardiovasc Intervent Radiol 13:140-145, 1990
  pubmed

• 47) 池田健次, 村島直哉, 竹内和男, 他:肝癌に対する動脈塞栓術後の肝動脈主幹部閉塞と肝動脈spasmとの関連について. 肝臓 25:1153-1159, 1984

[6] 肝癌に対する反復肝動脈塞栓術の効果と限界

P.114 掲載の参考文献

• 1) The Liver Cancer Study Group of Japan:Primary liver cancer in Japan. Cancer 60:1400-1411, 1987

• 2) The Liver Cancer Study Group of Japan:Primary liver cancer in Japan. Clinicopathological features and results of surgical treatment. Ann Surg 211:277-287, 1990

• 3) Wheeler PG, Melia W, Dubbins P, et al:Non-operative arterial embolization in primary liver tumors. Br Med J 2:242-244, 1979
  pubmed

• 4) Chuang VP, Wallace S:Hepatic artery embolization in the treatment of hepatic neoplasms. Radiology 140:51-58, 1981
  pubmed

• 5) Yamada R, Horikawa S, Fujiyama T, et al:Hepatic artery embolization in 120 patients with unresectable hepatoma. Radiology 148:397-401, 1983

• 6) Lin DY, Liaw YF, Lee TY, et al:Hepatic-arterial embolization in patients with unresectable hepatocellular carcinoma:A randomized controlled trial. Gastroenterology 94:453-456, 1988
  pubmed

• 7) 池田健次, 小宅映士, 熊田博光, 他:肝癌に対するtranscatheter arterial embolization therapyの評価. 日消誌81:249-253, 1984

• 8) Ikeda K, Kumada H, Saitoh S, et al:Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma:An analysisby Cox proportional hazard model. Cancer 68:2150-2154, 1991

• 9) 日本肝癌研究会:肝癌治療直接効果判定基準. 肝臓 35:193-205, 1994

• 10) 池田健次, 斉藤 聡, 熊田博光:肝動脈塞栓術症例での長期生存の条件. KARKINOS 7:261-267, 1994

• 11) 池田健次, 熊田博光:肝細胞癌に対する頻回肝動脈塞栓術による3年. 5年の長期生存とその諸条件. 肝臓 31:235-237, 1990

• 12) Kuroda C, Sakurai M, Monden M, et al:Limitation of transcatheter arterialchemoembolization using iodized oil for small hepatocellular carcinoma. A study in resected cases. Cancer 67:81-86, 1991

• 13) 大井博道, 山本忠司, 沢井ユカ, 他:肝細胞癌に対する区域性肝動脈-門脈同時塞栓化学療法 (セメント療法) の治療成績. 癌と化学療法 16 (part II):2853-2857, 1989

• 14) Uchida H, Ohishi H, Matsuo N, et al:Transcatheter hepatic segmental arterial embolization using Lipiodol mixed with an anticancer drug and Gelfoam particles for hepatocellular carcinoma. Cardiovasc Intervent Radiol 13:140-145, 1990
  pubmed

• 15) 池田健次, 村島直哉, 竹内和男, 他:肝癌に対する動脈塞栓術後の肝動脈主幹部閉塞と肝動脈spasmとの関連について. 肝臓 25:1153-1159, 1984

P.115 掲載の参考文献

• 16) 池田健次, 斉藤 聡, 荒瀬康司, 他:肝動脈塞栓術施行肝細胞癌にエタノール注入療法を併用する臨床的意義と治療効果-特に, 多発例に対する有用性の検討. 日癌治 26:58-65, 1991

[7] 肝動脈塞栓術の副作用と合併症

P.131 掲載の参考文献

• 1) 山田龍作, 中塚春樹, 中村健治, 他:肝細胞癌に対するtranscatheter arterial em-bolization therapyの有用性と肝機能に及ぼす影響. 日消誌 78:214-221, 1981

• 2) Kuroda C, Iwasaki M, Tanaka T, et al:Gall bladder infarction following hepatic transcatheter arterial embolization. Radiology 147:85-89, 1983

• 3) Takayasu K, Moriyama N, Muramatsu Y, et al:Gall bladder infarction after hepatic artery embolization. AJR 144:135-138, 1985
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• 4) Makuuchi M, Sukigara M, Mori T, et al:Bile duct necrosis:complication of transcatheter hepatic arterial embolization. Radiology 156:331-334, 1985
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• 5) 池田健次, 熊田博光, 中村郁夫, 他; 肝動脈塞栓術の食道静脈瘤に及ぼす影響. Gastroenterol Endoscopy 28:3073-3077, 1986

• 6) 井口 潔, 小林迫夫, 朔 元則, 他:門脈圧亢進症における門脈循環の特性と食道静脈瘤の成因に関する考察. 肝臓 18:891-898, 1977

• 7) 長崎嘉和:腹腔動脈造影による肝細胞癌の動門脈吻合に関する研究. 肝臓 20:180-188, 1979

• 8) 宮本二郎, 高瀬靖広, 福富久之, 他:食道静脈瘤患者における胃血行動態に関する内視鏡的検討. Gastroenterol Endoscopy 23:497-502, 1981

• 9) Hall DA, Clouse ME, Gramm HF:Gastroduodenal ulceration after hepatic arterial infusion chemotherapy. Am J Roentgenol 136:1216-1218, 1981

• 10) Chuang VP, Wallace S, Stroehlein J, et al:Hepatic arterial infusion chemotherapy:Gastroduodenal complications. Am J Roentgenol 137:347-350, 1981

• 11) 石塚達夫, 小坂譲二, 山北宜由, 他:Mitomycin C動注後の急性胃病変の内視鏡的検討. Gastroenterol Endoscopy 25:1493-1499, 1983

• 12) 池田健次, 熊田博光, 荒瀬康司, 他:肝動脈塞栓術に伴う胃十二指腸病変. Gastroenterol Endoscopy 30:683-690, 1988

[8] 肝細胞癌に対するSMANCSの効果

P.144 掲載の参考文献

• 1) Maeda H, Takeshita J, Kanamaru R:A lipophylic derivative of neocarzinostatin. A polymer conjugation of an antitumor protein antibiotic. Int J Peptide Protein Res 14:81-87, 1979

• 2) Nakamura H, Hashimoto T, Oi H, et al:Transcatheter oily chemoembolization of hepatocellular carcinoma. Radiology 170 (3):783-786, 1989
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• 3) 日高 仁, 小林尚志, 大山三郎, 他:原発性肝癌に対する油性抗癌剤 (Mitomycin C, Adriamycin) の肝動脈内注入療法. 日医放会誌 45:1430-1440, 1985

P.145 掲載の参考文献

• 4) Sasaki Y, Imaoka A:New approach to chemoembolization therapy for hepatoma using ethiodized oil, cisplatin, and gelatin sponge. Cancer 60:1194-1203, 1987

• 5) Maeda H, Takeshita J, Kanamaru R, et al:Antimetastatic and antitumor activity of a derivative of neocarzinostatin:An organic solvent and water-soluble polymer-conjugated protein. Gann 70:601-606, 1979
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• 6) 木村正美, 今野俊光, 大塚憲雄, 他:YM881 (SMANCS) の家兎VX2実験肝癌に対する抗腫瘍効果. 癌と化学療法 16:2183-2188, 1989
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• 7) 田口鐵男, 斎藤達雄, 太田 潤, 他:YM881 (ジノスタチンスチマラマー) 懸濁液の肝動注における第I相試験. 癌と化学療法 18:1657-1663, 1991

• 8) 田口鐵男, 斎藤達雄, 太田 潤, 他:YM881 (ジノスタチンスチマラマー) 油性懸濁液の肝動注における第II相試験. 癌と化学療法 18:1665-1675, 1991

• 9) 今野俊光, 前田 浩, 横山育三, 他:原発性肝癌の新治療法:油性リンパ管造影剤リピオドールと親油性高分子制癌剤スマンクスの肝動脈内投与とその臨床成績. 癌と化学療法 9:2005-2015, 1982
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• 10) 今野俊光, 岩井 顕, 牧祥二郎, 他:悪性固形腫瘍に対するSMANCS. リピオドール動脈内投与療法. 日癌治 18:1845-1851, 1983

• 11) 諏訪和弘, 佐藤守男, 浜地順子, 他:肝細胞癌門脈腫瘍浸潤例 (門脈本幹, 一次分枝閉塞例) に対するSMANCS-Lipiodol動脈内注入療法の検討. 肝臓 30:898-903, 1989

• 12) 日本肝癌研究会:肝癌治療直接効果判定基準. 肝臓35:194-205, 1994

• 13) Wheeler PG, Melia W, Dubbins P, et al:Non-operative arterial embolization in primary liver tumors. Br Med J 2:242-244, 1979
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• 14) Chuang VP, Wallace S:Hepatic artery embolization in the treatment of hepatic neoplasms. Radiology 140:51-58, 1981
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• 15) Okamura J, Horikawa S, Fujiyama T, et al:An appraisal of transcatheter arterial embolization combined with transcatheter arterial infusion of chemotherapeutic agent for hepatic malignancies. World J Surg 6:352-357, 1982
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• 16) Yamada R, Horikawa S, Fujiyama T, et al:Hepatic arterial embolization in 120 patients with unresectable hepatoma. Radiology 148:397-401, 1983

• 17) Lin DY, Liaw YF, Lee TY, et al:Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma:A randomized controlled trial. Gastroenterology 94:453-456, 1988
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• 18) Ikeda K, Kumada H, Saitoh S, et al:Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma:An analysis by the Cox proportional hazard model. Cancer 68:2150-2154, 1991
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[9] 肝細胞癌に対する集学的治療と将来

P.155 掲載の参考文献

• 1) The Liver Cancer Study Group of Japan. Primary liver cancer in Japan:Clinicopathological features and results of surgical treatments. Ann Surg 211:277-287, 1990

• 2) Prince AM, Szmuness W, Michon J, et al:A case-control study of the association between primary liver cancer and hepatitis B infection in Senegal. Int J Cancer 16:376-383, 1975

• 3) Obata K, Hayashi N, Motoike Y:Aprospective study on the development of hepatocellular carcinoma from liver cirrhosis with persistent hepatitis B virus infection. Int J Cancer 25:741-747, 1980

• 4) Bruix J, Calvet X, Costa J, et al:Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet 2:1004-1006, 1989
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• 5) Ikeda K, Saitoh S, Koida I, et al:Amultivariate analysis of risk factors for hepatocellular carcinogenesis:A prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 18:47-53, 1993