書籍詳細

第1章 活性酸素 (ROS)

P.21 掲載の参考文献

• 1-1) 城戸 亮:アミノ酸代謝とフリーラジカル. Biomedica 5(8):788-792, 1990.

• 1-2) Sakurai, T. , Sugioka, K. , Nakano, M.: O2 generation and lipid peroxidation during the oxidation of a glycated polypeptide in the presence of iron-ADP. Bioch. Biophys. Acta 1043: 27-33, 1990.

• 1-3) 長野哲雄:活性酸素生成と制御及び活性発現に関する生物有機化学的研究. 薬学雑誌 111(2):103-119, 1991.

• 1-4) Kaur, H. , Halliwell, B.: Action of biologically-relevant oxidizing species upon uric acid identification of uric acid oxidation products. Chem. -Biol. Interactions 73: 235-247, 1990.
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• 1-5) Lusthof, K. J. , Richter, W. , deMcl, N. J. , Janssen, L. H. M. , Verboom, W. , Reinhoudt, D. N.: Reductive bis(aziridinyl) benzoquinones by xanthine oxidase. Arch. of Biochem. Biophys. 277(1): 137-142, 1990.

• 1-6) Asanasev, I. B. , Korkina, L. G. , Suslova, T. B. , Soodaeva, S. K.: Are quinones producers or scavengers of superoxide ion in cell 2. Arch. of Biochem. Biophys. 281(2): 245-250, 1990.
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• 1-7) Shakarjian, M. P. , Carchman, R. C.: Alteration of human granulocyte functional responses by menadione. Arch. of Biochem. Biophys. 283(1): 1-11, 1990.
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• 1-8) Bandy, B. , Moon, J. , Davison, A. J.: Multiple actions of superoxide actions of 1 superoxide dismutase. Free Red. Biol. & Med. 9: 143-148, 1990.

• 1-9) Kahl, R. , Weinke, S. , Kappus, H.: Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole. Toxicology 59: 179-194, 1989.
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• 1-10) Oyanagui, Y.: Inhibition of superoxide anion production in non-stimulated guinea pig peritoneal exudate cells by anti-inflammatory drugs. Biochem. Pharmacol. 27: 777-782, 1978.
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• 1-11) Chan, P. C. , Bielski, B. H. J.: Glyceraldehyde-3-phosphate dehydrogenase-catalyzed chain oxidation of reduced nicotinamide adenine dinucletide by perhydroxyl radicals. J. Biol. Chem. 255(3): 874-876, 1980.

• 1-12) Mayo, L. A. , Curnutte, J. T.: Kinetic microplate assay for superoxide production by neutrophils and othor phagocytic cells. Method in Enzymol. 186: 567-579, Academic Press, 1990.

• 1-13) Blair, A. L. , Cree, I. A. , Beck, J. S.: Measurement of phagocyte chemiluminescence using microtitre plate luminometer. J. Bioluminescence and Chemiluminescence 3: 67-70, 1989.

• 1-14) Cree, I. A. , Blair, A. L. , Beck, J. S.: Use of a microtitre plate chemiluminescence reader to study surface phagocytosis by human moncytes. J. Bioluminescence and Chemiluminescence 3: 71-74, 1989.

• 1-15) Fattorossi, A. , Nisini, R. , Le Molo, S. , De Petrillo, G. , De Petrillo, G. , D'Amelio, R.: Flow cytometric evaluation of NBT reduction in human polymorphonuclear leukocytes. Cytometry 11: 907-912, 1990.

• 1-16) Kobzik, L. , Godlski, J. J. , Brain, J. D.: Oxidative metabolism in the alveolar macrophage: Analysis by flow cytometry. J. of. Leukocyte Biol. 47: 295-303, 1990.

• 1-17) Ryan, T. C. , Weil, G. J. , Newburger, P. E. , Haugland, R. , Simons, E. R.: Measure. ment of superoxide release in the phagovacuoles of immune complex-stimulated human neutrophils. J. of Immunolog. Methods 130: 223-233, 1990.

• 1-18) Kiel, J. L. , Bruno, J. G.: Interaction of the antioxidants 3-amino-tyrosine and diazoluminomelanin with cytochrome b of HL-60 cells. Pasadena Abst. 2. 28, 1990.

• 1-19) Bottu, G.: The effect of quenchers on the chemiluminescence of luminol and lucigenin. J. of Bioluminescence and Chemiluminescence 3: 59-65, 1989.

• 1-20) Oyanagui, Y.: Reevaluation of assay methods and establishment of kit for superoxide dismutase activity. Anal. Biobhem. 42: 290-296, 1984.

• 1-21) Archer, S. L. , Nelson, D. P. , Weir, E. K.: Detection of activated O2 species in vitro and in rat lungs by chemiluminescence. J. Appl. Physiol. 67(5): 1912-1921, 1989.
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• 1-22) Elferink, J. G. R. , de Koster, B. M. , Boonen, G. J. J. C.: Cytochalasin induced NBT reduction in polymorphonuclear Ieukocytes. Res. Commun. in Chem. Pathol. and Pharmacol. 68(2): 175-187, 1990.

• 1-23) Yamazaki, I. , Piette, L. H. , Grover, T. A.: Kinetic studies on spin trapping of superoxide and hydroxyl radicals generated in NADPH-cytochrome P-450 reductase-paraquat system. J. Biol. Chem. 265(2): 652-659, 1990.
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• 1-24) 末松 誠, 土屋雅春・他:血管内皮-顆粒球相互反応と活性酸素. フリーラジカルの臨床. (近藤元治・監修, 大柳善彦, 吉川敏一・編集), 4:51-57, 1990.

• 1-25) Babbs, C. F.: Histochemical demonstration of O2-generation by rat lung endothelium. Pasadena Abst. 3. 12, 1990.

• 1-26) Oyanagui, Y.: Inflammation and superoxide production by macrophages. Agents and Actions(Supp 1) 7: 174-179, 1980.

• 1-27) Hirai, K. , Moriguchi, K. , Wang, G-Y.: Human neutrophils produce free radicals from the cell-zymosan interface during phagocytosis and from the whole plasma membrane when stimulated with calcium ionophore A 23187. Expt'l. Cell Res. 194: 19-27, 1991.

• 1-28) Halliwell, B. , Grootveld, M.: The measurement of free radical reaction in humans. FEBS Letts. 213(1): 9-14, 1987.

• 1-29) Davis, W. B. , Mohammed, B. S. , Mays, D. C. , She, Z. -W. , Mohammed, J. R. , Husney, R. M. , Sagone, A. L.: Hydroxylation of salicylate by activeted neutrophils. Biochem. Pharmacol. 28(2): 4013-4019, 1989.

• 1-30) Babbs, C. F. , Griffin, D. W.: Scatchard analysis of methane sulfinic acid production from dimethyl sulfoxide. Free Rad. Biol. & Med. 6: 493-503, 1989.
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• 1-31) Babbs, C. F. , Gale, M. J.: Colorimetric assay for methanesulfinic acid in biological samples. Analy. Biochem. 163: 67-73, 1987.

• 1-32) Babbs, C. F. , Steiner, M. G.: Pasadena Abst. 3. 11, 1990.

• 1-33) Steines, M. G. , Babbs, C. F.: Arch. of Biochem. Biophys. 278(2): 478-481, 1990.

• 1-34) Babbs, C. F. , Steiner, M. G.: Detection and quantitation of hydroxyl radical using dimethl sulfoxide as molecular probe. Academic Press, 1990.

• 1-35) LeBel, C. P. , Bondy, S. C.: Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem. Int. 17(3): 435-440, 1990.
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• 1-36) Robinson, J. P. , Bruner, L. H. , Bassoe, C-F. , Hudson, J. L. , Ward, P. A. , Pham, S. H.: Measurement of intracellular fluorescence of human monocytes relative to oxidative metabolism. J. of Leukocyte Biol. 43: 304-310, 1988.

• 1-37) Varma, S. D. , Devamanoharan, P. S.: Excretion of hydrogen peroxide in humanurifie. Free Red. Res. Comms. 8(2): 73-78, 1990.

• 1-38) 菊川清見:過酸化脂質測定法の最近の進歩. ファルマシア 25(12):1246-1252, 1989.

• 1-39) Pryor, W. A.: On the detection of lipid hydroperoxides in biological samples. Free Rad. Biol. & Med. 7: 177-178, 1989.
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• 1-40) 戸谷洋一郎:過酸化脂質の定量法. ぶんせき 7:527-533, 1990.

• 1-41) 八木國夫, 大石誠子, 大川 博:測定法. 過酸化脂質と疾患. (八木國夫, 五島雄一郎編集), 医学書院, 東京, 1981, p 20-32.

• 1-42) Bidder, T. G. , Sipka, B. M.: A modification of the thiobarbituric acid reaction. Lipids 24: 656-658, 1989.
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• 1-43) Fulceri, R. , Pompella, A. , Benedetti, A. , Comporti, M.: On the role of lipid peroxidation in the haloalkane-induced in activation of microsomal glucose 6 phosphatase. Res. Commun. in Chem. Pathol. and Pharmacol. 68(1): 73-88, 1990.
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• 1-44) Yamamoto, Y. , Ames, B. N.: Detection of lipid hydroperoxides and hydrogen peroxide at picomole levels by an HPLC and isoluminol chemiluminescence assay. Free Rad. Biol. & Med. 3: 359-361, 1987.
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• 1-45) Miyazawa, T.: Determination of phospholipid hydroperoxides in human blood plasma by a chemiluminescence-HPLC assay. Free Rad. Biol. & Med. 7: 209-217, 1989.
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• 1-46) Werner, A. , Grune, T. , Siems, W. , Schneider, W. , Shimasaki, H. , Esterbauer, H. , Gerber, G.: Nucleotide and aldehyde analysis by HPLC for determination of radical induced damage. Chromatographia 28(1/2): 65-68, 1989.

第2章 活性酸素消去酵素

P.52 掲載の参考文献

• 2-1) Paoletti, F. , Mocali, A.: Determination of SOD activity by purely chemical system based on NAD(P)H oxidation. Method of Enzymol. 186: 209-221, Academic Press, 1990.

• 2-2) Nakano, M.: Assay for SOD basad on chemiluminescence of luciferin analog. 186:p 227-237. Academic Press, 1990,

• 2-3) Kurobe, N. , Suzuki, F. , Kato, K. , Sato, T.: Sensitive immunoassay of rat Cu/Zn-SOD. Biomed. Res. 11(3): 187-194, 1990.

• 2-4) Oka, S. , Ogino, K. , Matsuura, S. , Yoshimura, S. , Yamamoto, K. , Okazaki, Y. , Takemoto, T. , Kato, N. , Uda, T.: Human serum immunoreactive copper, zinc-SOD assayed with an enzyme monoclonal immunosorbent in patients with digestive cancer. Clinica Chimica Acta 182: 209-220, 1989.

• 2-5) Oyanagui, Y.: Reevaluation of assay methods and establishment of kit for SOD activity. Anal. Biochem. 42: 290-296, 1984.

• 2-6) 大柳善彦: SOD活性測定亜硝酸法とそのキット化. 炎症 4(1):63-73, 1984.

• 2-7) Disilvestro, R. A. , David, C. , David, E A.: Comparison of four indirect methods for fluid SOD activities. Free Rad. Biol. & Med. 10: 507-510, 1990.

• 2-8) Marquez, L. A. , Dunford, H. B.: Reaction of autoxidation products of pemicillamine with myeloperoxidase. Biochem. Biophys. Res. Commun. 169(3): 1158-1163, 1990.
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• 2-9) Yano, S.: Multiple isoelectric variants of Cu, Zn-SOD from rat liver. Arch. of Biochem. Biophys. 279(1): 60-69, 1990.
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• 2-10) Hoerter, J. , Eisenstark, A. , Touati, D.: Mutations by near-ultraviolet radiation in Escherichia coli strains lacking SOD. Mutation Res. 215: 161-165, 1989.
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• 2-11) Touati, D.: The molecular genetics of SOD in E. coli. Free Rad. Res. Comms. 8 (1): 1-9, 1989.

• 2-12) Shen, J. , Subramanian, S. , Wong, C. F.: SOD: Fluctuations in the structure and solvation of the active site channel studied by molecular dynamics simulation. Biopolymers 28: 2085-2096, 1989.

• 2-13) Tibell, L. , Hjalmarsson, K. , Edlund, T. , Skogman, G. , Engstrom, A. , Aasa, R. , Marklund, S.: Cloning and characterization of human EC-SOD. Oxy-Radicals in Mol. Biol. and Pathol. (ed. Cerutti, P. A. , Fridovich, I. , McCord, J. M. (Alan R. Liss. Inc. )) 1988, p 233-245.

• 2-14) Marklund, S. L.: Location and regulation of EC-SOD synthesis. Pasadena Abst. 14. 4, 1990.

• 2-15) Sandstrom, J. , Hjalmarsson, K. , Carlsson, L. , Edlund, T. , Marklund, S. L.: Identification of the heparin binding of EC-SOD C. Pasadena Abst. 14. 33, 1990.

• 2-16) Karlsson, K. , Marklund, S. L. , Sandstrdm, J. M.: Proteolytic conversion of ECSOD type C to type B and A. Pasadena Abst. 14. 21, 1990.

• 2-17) Salo, D. C. , Lin, S. W. , Pacifici, R. E. , Davies, K. J. A.: SOD is preferentially degradaded by a proteolytic system from red blood cells following oxidative modification by hydrogen peroxide. Free Rad. Biol. & Med. 5: 335-339, 1988.

• 2-18) Capo, C. R. , Polticelli, F. , Calabresse, L. , Schinina, M. E. , Carri, M. T. , Rotilio, G.: The Cu, Zn-SOD isoenzymes of Xenopus laevis. Biochem. Biophys. Res. Commun. 173(3): 1186-1193, 1990.

• 2-19) Rotilio, G. , Paci, M. , Ciriolo, M. R.: GSH as an antioxidant: New functions in the physiological activation of Cu, Zn-SOD, copper transpart and transmembrane transduction of reducing power. Pasadena Abst. 2. 3, 1990.

• 2-20) Beyer, Jr. W. F. , Fridovich, I.: Phosphate, not SOD, facilitates electron transfer from ferrous salts to cytochrome c. Arch. of Biochem. Biophys. 285(1): 60-63, 1991.

• 2-21) Yim, M. B. , Chock, P. B. , Stacltman, E. R.: Copper, zinc SOD catalyzes hydroxyl radical production from hydrogen peroxide. Proc. Natl. Acad. Sci. USA 87: 5006-5010, 1990.

• 2-22) Barra, D. , Schinina, ME. , Bossa, F. , Puget, K. , Durosay, P. , Gnissani, A. , Michelson, AM.: A tetrameric SOD from the eucaryote Tetrahymena pyriformis. J. Biol. Chem. 265(29): 17680-17687, 1990.

• 2-23) Barkley, K. B. , Gregory, E M.: Tetrameric manganese SOD from anaerobic Actinomyces. Arch. of Biochem. Biophys. 280(1): 192-200, 1990.
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• 2-24) Bricker, B. J. , Tabatabai, L. B. , Judge, B. A. , Deyoe, B. L. , Mayfield, J. E.: Cloning, expression, and occurrence of the Brucella Cu, Zn-SOD. Infection and Immunity 58(9): 2935-2939, 1990.
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• 2-25) Nare, B. , Smith, J. M. , Prichard, R. K.: Schistosoma mansoni: Levels of antioxidants and resistance to oxidants increase during development. Expt'l. Parasitology 70: 389-397, 1990.

• 2-26) Getzoff, E. D. , Tainer, J. A. , Stempien, M. M. , Bell, G. I. , Hallewell, R. A.: Evolution of Cu, Zn-SOD and the Greek keyB-barrel structural motif: Proteins. Structure Function and Genetics 5: 322-336, 1989

• 2-27) Seto, N. O. L. , Hayashi, S. , Tener, G. M.: Overexpression of Cu, Zn-SOD in Dorosophila does not affect life-span. Proc. Natl. Acad. Sci. USA 87: 4270-4274, 1990.

• 2-28) Munkres, K. D.: Genetic coregulation of longevity and antioxienzymes in Neurospora crassa. Free Rad. Biol. & Med. 8: 355-361, 1990.
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• 2-29) Ischiropoulos, H. , Nazdiejko, C. E. , Kikkawa, Y.: Effect of aging on pulmonary SOD. Mechanisms of Ageing and Development 52: 11-26, 1990.

• 2-30) Izokun-Etiobhio, B. O. , Oraedu, A. C. I. , Ugochukwu, E. M.: A comparative study of SOD in various animal species: Comp. Biochem. Physiol. 95B(3): 521-523, 1990.

• 2-31) Buzad2i6, B. , Spasi6, M. , Saicic, Z. S. , Rodojicic, R. , Petrovic, V. M. , Halliwell, B.: Antioxidant defenses in the ground squirrel Citellus citellus. Free Rad. Biol. & Med. 9: 407-413, 1990.

• 2-32) Ahmad, S. , Pritsos, C. A. , Pardini, R. S.: Antioxidant enzyme activities in subcellular fractions of larvae of the black swallow-tail butterfly. Arch. of Insect Biochem. Biophysiol. 15: 101-109, 1990.

• 2-33) Hassan, H. M. , Moody, C. S.: Regulation of the biosynthesis of SOD in procaryotes. Superoxide and Superoxide Dismutase in Chem. Biol. Med. (ed. Rotilio, G. ) Elsevier Sci. Pub. 1986, p 274-279.

• 2-34) Niwa, Y. , Ishimoto, K. , Kanoh, T.: Induction of SOD in leukocytes by paraquat. Blood 76(4): 835-841, 1990.
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• 2-35) Stevens, T. M. , Boswell, Jr. G. A. , Adler, R. , Ackerman, N. R. , Kerr, J. S.: Induction of antioxidant enzyme activities by a phenylurea derivative. EDU, Toxicol. and Appl. Pharmacol. 96: 33-42, 1988.

• 2-36) Montesano, L. , Carri, M. T. , Mariottini, P. , Amaldi, F. , Rotilio, G.: Developmental expression of Cu, Zn-SOD in Xenopus. Eur. J. Biochem. 186: 421-426, 1989.

• 2-37) Privalle, C. T. , Fridovich, I.: Anaerobic biosynthesis of an inactive Mn-containing SOD in E. coli. Oxy-Radicals in Mol. Biol. and Pathol. (ed. Cerutti, P. A. , Fridovich, I. , McCord, J. M. ) Alan R. Liss, Inc. , 1988, p 195-211.

• 2-38) Wong, G. H. W. , Goeddel, D. V.: Induction of manganous SOD by tumor necrosis factor: Possible protective mechanism. Science 242: 941-944, 1988.

• 2-39) Wong, G. H. W. , Elwell, J. H. , Oberley, L. W. , Goeddel, D. V.: Manganous SOD is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell 58: 923-931, 1989.

• 2-40) Visner, G. A. , Dougall, W. C. , Wilson, J. M. , Burr, I. A. , Nick, H. S.: Regulation of manganese SOD by lipopolysaccharide, interleukim-1, and tumor necrosis factor. J. of Biol. Chem. 265(5): 2856-2864, 1990.
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• 2-41) Asoh, K. , Watanabe, Y. , Mizoguchi, H. , Mawatari, M. , Ono, M. , Kohno, K. , Kuwano, M.: Induction of manganese SOD by tumor necrosis factor in human breast cancer MCF-7 cell line and its TNF-resistant variant. Biochem. Biophys. Res. Commun. 162(2): 794-801, 1989.
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• 2-42) Iwamoto, S. , Takeda, K. , Kamijo, R. , Konno, K.: Induction of resistance to TNF cytotoxicity and mitochondrial SOD on U-937 cells by 1, 25-dihydroxy vitamin D3. Biochem. Biophys. Res. Commun. 170(1): 73-79, 1990.

• 2-43) Kyle, M. E. , Nakae, D. , Sakaida, I. , Miccadei, S. , Farber, J. L.: Endocytosis of SOD is required in order for the enzyme to protect hepatocytes from the cytotoxicity of hydrogen peroxide. J. of Biol. Chem. 263(8): 3784-3789, 1988.

• 2-44) Dini, L. , Rotilio, G.: Electron microscopic evidence for endocytosis of SOD by hepatocytes using protein-gold adducts. Biochem. Biophys. Res. Commun. 162 (3): 940-944, 1989.

• 2-45) Scott, M. D. , Eaton, J. W. , Kuypers, F. A. , Chiu, D. T. -Y. , Lubin, B. H.: Enhancement of erythrocyte SOD activity. Blood 74(7): 2542-2549, 1989.

• 2-46) Nakae, D. , Yoshiji, H. , Amanuma, T. , Kinugasa, T. , Farber, J. L. , Konishi, Y.: Endocytosis-independent uptake of liposome-encapsulated SOD prevents the killing of cultured hepatocytes by tert-butyl hydroperoxide. Arch. Biochem. Biophys. 279(2): 315-319, 1990.

• 2-47) Greenwald, R. A.: SOD and catalase as therapeutic agents for human diseases. Free Rad. Biol. & Med. 8: 201-209, 1990.
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• 2-48) Inoue, M. , Ebashi, I. , Watanabe, N. , Morino, Y.: Synthesis of a SOD derivative that circulates bound to albumin and accumulates in tissue whose pH is decreased. Biochem. 28: 6619-6624, 1989.

• 2-49) 桜井勝清, 宮崎匡輔:公開特許公報(A) 平 2-273176. グリコサミノグリカンで修飾されたスーパーオキシドジスムターゼおよびその製造法. 公開・平成2年, 1990, 11月7日.

• 2-50) Yamamoto, K. , Volkl, A. , Hashimoto, T. , Fahimi, H. D.: Catalase in guinea pig hepatocytes is localized in cytoplasma, nuclear matrix and peroxisomes. Eur. J. of Cell Biol. 46: 129-135, 1988.
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• 2-51) Condel, R. A. , Tappel, Al. L.: Evidence for stability of glutathione peroxidase as aprotective enzyme. Arch. of Biochem. Biophys. 223(2): 407-416, 1983.

• 2-52) Esworthy, R. S. , Chu, F. -F. , Paxton, R. J.: Human plasma glutathione peroxidase is a distinct protein from intracellular glutathione peroxidase. Pasadena Abst. 1. 10, 1990.

• 2-53) Beutler, E. , Matsumoto, F.: Ethnic variation in red cell glutathione peroxidase activity. Blood 46(1): 103-110, 1975.
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• 2-54) Lalitha, K. , Narayanaswami, V.: Selenium mediated regulations in mitochondrial oxygen metabolism. Pasadena Abst. 11. 24, 1990.

• 2-55) Tho, L. L. , Candlish, J. K. , Thai, A. C.: Superoxide and peroxide decomposing enzymes in the circulating lymphocytes of diabetics. Med. Sci. Res. 15: 1457-1459, 1987.

• 2-56) Tietze, F. , : Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27: 502-522, 1969.
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第3章 ラジカルスカベンジャー

P.70 掲載の参考文献

• 3-1) Ulvik, R. J. , Bolann, B. J.: Ferritin, a novel antioxidant?. Pasadena Abst. 2. 52, 1990.

• 3-2) Ribo, J. M. , Farrera, J. A. , Claret, J.: Proton-induced dismutation of superoxide in a protic media by bile pigments. Experientia 46: 63-67, 1990.

• 3-3) Sharonov, B. P. , Govorova, N. J. , Lyzlova, S. N.: Carnosine as a potential scavenger of oxidants generated by stimulated neutrophils. Biochemistry International 21 (1): 61-68, 1990.

• 3-4) 三井 彰, 平川 忠: 成人T細胞白血球由来因子/ヒトチオレドキシン(ADF/hTX), 生化学 62(8): 1047-1051, 1990.

• 3-5) Haenen, G. R. M. M. , de Rooij, B. M. , Timmerman, H. , Bast, A.: B-adrenergic agonists do not reduce hydrogen peroxide production from superoxide radicals. Arch. Int. Pharmacodyn. 300: 68-75, 1989.

• 3-6) Hatano, T. , Yasuhara, T. , Yoshihara, R. , Agata, T. , Noro, T. , Okuda, T.: Effects of interaction of tannins with co-existing substances VII. Chem. Pharm. Bull. 38 (5): 1224-1229, 1990.

• 3-7) Huguet, A. L. , Mafiez, S. , Alcaraz, M. J.: Superoxide scavenging properties of flavonoids in a non-enzymatic system. Z. Naturforsch. 45C: 19-24, 1990.

• 3-8) Tong-Jun, L. , Geng-Tao, L. , Xiao-Jie, L. , Bao-Lu, Z. , Wen-Juan, X.: Detection of free radical scavenging activity of schisanhenol by electron spin resonance. Acta Pharmacologica Sinca. 11(6): 534-539, 1990.

• 3-9) Li, X. , Zhao, B. , Liu, G. , Xin, W.: Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations. Free Rad. Biol. & Med. 9: 99-104, 1990.

• 3-10) Kunchandy, E. , Rao, M. N. A.: Generation of superoxide anion and hydrogen peroxide by(+) -cyanidanol-3. Int'l. J. of Pharmaceutics 65: 261-263, 1990.

• 3-11) Ariga, T. , Hamano, M.: Radical scavenging action and its mode in procyanidins B-1 and B-3 from azuki beans to peroxyl radicals. Agric. Biol. Chem. 54(10): 2499-2504, 1990.

• 3-12) Krol, W. , Czuba, Z. , Scheller, S. , Gabrys, J. , Grabiec, S. , Shani, J.: Anti-oxidant property of ethonolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminol. Biochemistry International 21(4): 593-597, 1990.

• 3-13) 大西基代, 戸田静男, 菅田良仁, 東家一雄, 黒岩共一, 木村通郎:艾及び艾燃焼生成物のスーパーオキシドに対する作用. 全日本鍼灸会雑誌 40(2):228-231, 1990.

• 3-14) SteinKuhler, C. , Mavelli, I. , Rossi, L. , Pedersen, J. Z. , Melina, G. , Weser, U. , Rotilio, G.: Cytotoxicity of low molecular weight Cu2Zn2-SOD active center analog in human erythroleukemia cells. Biochem. Pharmacol. 39(9): 1473-1479, 1990.

• 3-15) Miesel, R. , Hartman, H-J. , Weser, U.: Antiinflammatory reactivity of copper(1)-thionein. Inflammation 14(5): 471-483, 1990.

• 3-16) Darr, D. J. , Yanni, S. , Pinnell, S. R.: Protection of Chinese hamster ovary cells from paraquat-mediated cytotoxicity by a Iow molecular weight mimic of SOD (DF-Mn). Free Rad. Biol. & Med. 4: 357-363, 1988.

• 3-17) 長野哲雄:活性酸素生成と制御及び活性発現に関する生物有機化学的研究. 薬学雑誌 111(2):103-119, 1991.

• 3-18) Lozovskaya, E. L. , Kapunsky, G. D. , Sapezhinsky, I. I.: SOD activity and photosensitizing properties of 2, 5-dihydrobenzolsulphonate. Biofizika 35(6): 912-916, 1990, (in Russian with Engl. abst. ).

• 3-19) Mitchell, J. B. , Samuni, A. , Krishna, M. C. , DeGraff, W. G. , Ahn, M. S. , Samuni, U. , Russo, A.: Biologically active metal-independent SOD minics. Biochemistry 29: 2802-2807, 1990.

• 3-20) Kelner, M. J. , Bagnell, R. , Welch, K. J.: Thioureas react with superoxide radicals to yield a sulfhydryl compound. J. of Biol. Chem. 265(3): 1306-1311, 1990.
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• 3-21) Bonne, C. , Muller, A. , Latour, E. , Tissie, G. , Emerit, I. , Modat, G. , 2 Dornand, J. , Roch, M. , Giroud, J. P. , Gridswold, D. E. , Marshall, P. J. , Coquelet, C.: 2-(2-hydroxy-4-methyl-phenyl) aminothiazole hydrochloride as a dual inhibitor of cyclooxygenase/lipoxygenase and a free radical scavenger. Arzneim-Forsch/Drug Res. 39(II) Nr10: 1242-1250, 1989.

• 3-22) Ghoshal, A. K. , Rushmore, T. H. , Buc-Calderon, P. , Roberfroid, M. , Farber, E.: Prevention by free radical scavenger AD50f prooxidant effects of choline deficiency. Free Rad. Biol. & Med. 8: 3-7, 1990.
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• 3-23) Biagi, G. , Livi, O. , Ramaccioti, G. L. , Scartoni, V.: SOD-like activity of 1, 2, 3, riazole derivatives. II Farmaco. 45(1): 49-57, 1990.

• 3-24) Tadolini, B. , Cabrini, L.: The influence of pH on . OH scavenger inhibition of damage to deoxyribose by Fenton reaction. Mol. and Cellul. Biochem. 94: 97-104, 1990.

• 3-25) Haseloff, R. F. , Blasig, I. E. , Meffert, H. , Ebert, B.: Hydroxyl radical scavenging and antipsoriatic activity of benzoic acid derivatives. Free Red. Biol. & Med. 9: 111-115, 1990.

• 3-26) Hicks, M. , Wong, L. , Day, R. O.: Antioxidant activity of propylthiouracil. Pasadena Abst. 2. 21, 1990.

第4章 抗酸化剤

P.91 掲載の参考文献

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• 4-12) Kagan, V. E. , Serbinova, E. A. , Koynova, G. M. , Kitanova, S. A.: Antioxidant action of ubiquinol homologues with different isoprenoid chain length in biomembranes. Free Rad. Biol, & Med. 9: 117-126, 1990,
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• 4-13) Landi, L. , Cabrini, L. , Fiorentini, D. , Sechi, A. M. , Sartor, G. , Pasquali, P. , Masotti, L.: Coenzyme Q-3 as an antioxidant. Cell Biophysics 16: 1-12, 1990.
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• 4-14) Villamil, S. F. , Dubin, M. , Galeffi, C. , Stoppani, A. O. M.: Effect of mansonones on lipid peroxidation, P 450 monooxygenase activity, and superoxide anion genera-tion by rat liver microsomes. Biochem. Pharmacol. 40(10): 2343-2351, 1990.

• 4-15) Turner, E. , Hager, L. J. , Shapiro, B. M.: Ovothiol replaces glutathione peroxidase as a hydrogen scavenger in sea urchin eggs. Science 242: 939-941, 1988.
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• 4-17) Holler, T. P. , Hopkins, P. B.: Ovothiols as free-radical scavengers and the mechanism of ovothiol-promoted NAD(P)H-02 Oxidoreductase activity. Biochemistry 29: 1953-1961, 1990.

• 4-18) Sassa, H. , Takaishi, Y. , Terado, H.: The triterpene celasterol as a very potent inhibitor of lipid peroxidation in mitochondria. Biochem. Biophys. Res. Commun. 172(2): 890-897, 1990.

• 4-19) Igarashi, K. , Itoh, M. , Harada, T.: Major antioxidative substances in leaves of atsumi-kabu(red turnip). Agric. Biol. Chem. 54(4): 1053-1055, 1990.

• 4-20) Shin-ya, K. , Imai, S. , Furihata, K. , Hayakawa, Y. , Kato, Y. , Vanduyne, G. D. , Clardy, J. , Seto, H.: Isolation and structural elucidation of an antioxidative agent, naphterpin. J. of Antibiotics 18(4): 444-447, 1990.

• 4-21) Kato, S. , Kawai, H. , Kawasaki, T. , Toda, Y. , Urata, T. , Hayakawa, Y.: J. of Antibiotics 17(12): 1879-1881, 1989.

• 4-22) Yuting, C. , Rongliang, Z. , Zhongjian, J. , Yong, J.: Flavonoids as superoxide scavengers and antioxidants. Free Rad. Biol. & Med. 9: 19-21, 1990.

• 4-23) Carini, R. , Comoglio, A. , Albano, E. , Morazzoni, P. , Magistretti, M. J. , Poli, G.: Antioxidant activity of JdB 1016, a new flavolignant complex. Pasadena Abst. 2. 11, 1990.

• 4-24) Hirano, T. , Oka, K. , Akiba, M.: Effects of synthetic and naturally occuring flavonoids on Na+, K+-ATPase. Life Sci. 45: 1111-1117, 1989.
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• 4-25) 清水 寛, 土屋浩一郎, 桜井 弘:鎮痛, 消炎作用を有する漢方方剤のスーパーオキシドジスムターゼ様活性. 和漢医薬学会誌 7:54-60, 1990.

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• 4-28) Serbinova, E. , Kagan, V. , Han, D. , Packer, L.: D-alpha-tocotrienol is a more powerful membrane antioxidant than D-alpha-tocopherol. Pasadena Abst. 2. 4, 1990.

• 4-29) Lippa, S. , Oradei, A. , Aureli, V. , Dordoni, P. L. , Bracali, A. M. , Arpino, L. , Littarra, C. R.: Effect of anaesthesia and surgical stress on plasma levels of peroxidation products and antioxidants. Pasadena Abst. 2. 31, 1990.

• 4-30) Kagan, V. , Serbinova, E. , Packer, L.: Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocophenol recycling. Biochem. Biophys. Res. Commun. 169(3): 851-857, 1990.

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• 4-32) Janero, D. A. , Cohen, N. , Burghardt, B. , Schaer, B. H.: Novel 6-hydroxychroman-2-carbonitrile inhibitors of membrane peroxidative injury. Biochem. Pharmacol. 40(3): 551-558, 1990.
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• 4-33) Grisar, J. M. , . Petty, M. A. , Bolkenius, F N. , Dow, J. , Wagner, J. , Wagner, E. R. , Haegele, K. D. , De Jong, W.: Acardioselective hydrophilic N, N. N-trimethylethanaminiuma-tocopherol analogue that reduces myocardial infarct size. J. Med. Chem. 34: 257-260, 1991.

• 4-34) Costagliola, C. , Menzione, M.: Effect of vitamin E on the oxidative state of glutathione in plasma. Clin. Physiol. Biochem. 8: 140-143, 1990.
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• 4-35) Ohkawa, S. , Terao, S. , Terashita, Z. , Shibouta, Y. , Nishikawa, K.: Dual inhibitors of thromboxane A2 synthesis and 5-lipoxygenase with scavenging activity of active oxygen species. J. Med. Chem. 34: 267-276, 1991.
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• 4-36) Krishna, C. M. , Hahn, S. , Mitchell, J. B. , Russo, A.: The protection role of Tiron against oxidative damage in mammalian cells. Pasadena Abst. 2. 13, 1990.

• 4-37) Uehara, Y. , Shirahase, H. , Nagata, T. , Ishimitsu, T. , Morishita, S. , Osumi, S. , Matsuoka, H. , Sugimoto, T.: Radical scavengers of indapamide in prostacyclin synthesis in rat smooth muscle cell. Hypertension 15: 216-224, 1990.
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• 4-39) Serbinova, E. A. , Kharfur, M. , Utkin, L. Y. , Komissarov, V. P. , Erin, A. N. , Kakovsky, S. , Savov, V. , Kagan, V. E.: Mechanism of antioxidant effect of shielded phenols in biological membranes. Byull. Eksp. Biol. Med. 110(11): 486-489, 1990. (Russian with English abstract).

• 4-40) Kagan, V. E. , Serbinova, E. A. , Packer, L.: Generation and recycling of radicals from phenolic antioxidants. Arch. of Biochem. Biophys. 280(1): 33-39, 1990.
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• 4-41) Miyano, S. , Tatsuoka, T. , Suzuki, K. , Imao, K. , Satoh, F. , Ishihara, T. , Hirotsu, I. , Kihara, T. , Hatta, M. , Horikawa, Y. , Sumoto, K.: The synthesis and antilipidper-oxidation activity of 4, 4-diarylbutylamines and 4, 4-diarylbutanamides. Chem. Pharm. Bull. 38(6): 1570-1574, 1990.

• 4-42) Wlodek, L. , Czubak, J.: The antioxidative properties of thiazolidine dervatives. Pol. J. Pharmacol. Pharm. 41: 369-375, 1989.

• 4-43) Kagan, V. , Khan, S. , Swanson, C. , Shvedova, A. , Serbinova, E. , Packer, L.: Antioxidant action of thioctic and dihydrolipoic acid. Pasadena Abst. 2. 26, 1990.

• 4-44) Braughler, J. M. , Pregenzer, J. F.: The 21-aminosteroid inhibitors of lipid peroxidation. Free Rad. Biol. & Med. 7: 125寸30, 1989.

• 4-45) Gulumian, M. , Bhoolia, D.: Ability of 21-aminosteroids to protect human blood cells against asbestos-induced hemolysis. Pasadena Abst. 2. 16, 1990.

• 4-46) Wiseman, H. , Cannon, M. , Arnstein, H. R. V. , Halliwell, B.: Mechanism of inhibition of lipid peroxidation by tamoxifen and 4-hydroxy tamoxifen introduced into liposomes. FEBS Letts. 274(1-2): 107-110, 1990.

第5章 白血球などの活性酸素生成機構

P.111 掲載の参考文献

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• 5-2) Holian, A. , Jordan, M. K. , Nguyen, H. V. , Deveny, Z. J.: Inhibition of macrophage activation by isoquinolinesulfonamide, phenothiazine and napthalene-sulfonamide. J. of Cellul. Physiol. 137: 45-54, 1988.

• 5-3) Aida, Y. , Pabst, M. J. , Rademacher, J. M. , Hatakeyama, T. , Aono, M.: Effects of polymyxin B on superoxide anion release and priming in human polymorphonuclear leukocytes. J. of Leukocyte Biol. 47: 283-291, 1990.
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• 5-4) Ohtsuka, T. , Ozawa, M. , Okamura, N. , Ishibashi, S.: Stimulatory effects of a short chain phosphatidate on superoxide anion production in guinea pig polymorphonuclear leukocytes. J. Biochem. 106: 259-263, 1989.

• 5-5) Ohtsuka, T. , Hiura, M. , Ozawa, M. , Okamura, N. , Ishibashi, S.: Synergism between platelet-activating factor and diacylglycerol in the induction of superoxide anion production in guinea pig polymorphonuclear leukocytes. Arch. Biochem. Biophys. 279(1): 21-24, 1990.
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• 5-6) Heyworth, P. G. , Curnutte, J. T. , Nauseef, W. M. , Volpp, B. D. , Peason, D. W. , Rosen, H. , Clark, R. A.: Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assernbly. J. Clin. Invest. 87: 352-356, 1991.

• 5-7) Parkos, C. A. , Dinauer, M. C. , Walker, L. E. , Allen, R. A. , Jesaitis, A. J. , Orkin, S. H.: Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b. Proc. Natl. Acad. Sci. USA 85: 3319-3323, 1988.
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• 5-8) Teahan, C. G. , Totty, N. , Casimir, C. M. , Segal, A. W.: Purification of the 47kDa phosphoprotein associated with the NADPH oxidase of human neutrophils. Biochem. J. 267: 485-489, 1990.

• 5-9) Pick, E. , Kroizman, T. , Abo, A.: Activation of the superoxide-forming NADPH oxidase of macrophages requires two cytosolic components. J. of Immunol. 143: 4180-4187, 1989.
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• 5-11) Clark, R. A.: The human neutrophil respiratory burst oxidase. J. Infectious Dis. 161: 1140-1147, 1990.

• 5-11a) Rotstein, O. D. , Fiegel, V. D. , Richard, B. S. , Simmons, L. , Knighton, D. R.: The deleterious effect of reduced pH and hypoxia on neutrophil migration in vitro. J. of Surgical Res. 45: 298-303, 1988.

• 5-12) Ohkubo, T. , Tsuda, M. , Tamura, M. , Yamamura, M.: Impaired superoxide production in peripheral blood neutrophils of germ-free rats. Scand. J. Immunol. 32: 727-729, 1990.
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• 5-13) Henderson, L. M. , Chappell, J B. , Jones, O. T. G.: Superoxide generation is inhibited by phospholipase A2 inhibitors. Biochem. J. 264: 249-255, 1989.

• 5-14) Bonser, R. W. , Thompson, N. T. , Randall, R. W. , Garland, L. G.: Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil. Biochem. J. 264: 617-620, 1989.
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• 5-15) Thompson, N. T. , Tateson, J. E. , Randall, R. W. , Spacey, G. D. , Bonser, R. W. , Garland, L. G.: The temporal relationship between phospholipase activation, diacylglycerol formation and superoxide production in the human neutrophil. Biochem. J 271: 209-213, 1990.
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• 5-16) Ishihara, Y. , Rosolia, D. L. , McKenna, P. J. , Peters, S. P. , Albertine, K. H. , Gee, M. H.: Calcium is required for PMA induced superoxide release from human neutro. phils. J. of Leukocyte Biol. 48: 89-96, 1990.

• 5-17) Kettle, A. J. , Winterbourn, C. C.: Superoxide enhances hypochlorous acid production by stimulated human neutrophils. Biochim. Biophys. Acta 1052: 379-385, 1990.
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• 5-18) Shepherd, V. L. , Hoidal, J. R.: Clearance of neutrophil-derived myeloperoxidase by the macrophage mannose receptor. Am. J. Respir. Cell. Mol. Biol. 2: 335-340, 1990.
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• 5-20) Knighton, D. R. , Fiegel, V. D. , Halverson, T. , Schneider, S. , Brown, T. , Wells, C. L.: Oxygen as an antibiotic-The effect of inspired oxygen on bacterial clearance. Ann. Surg. 125: 97-100, 1990.

• 5-21) Kalra, J. , Chaudhary, A. K. , Massey, K. L. , Prasad, K.: Effect of oxygen free radicals, hypoxia and pH on the release of liver lysosomal enzymes. Mol. and Cellul. Biochem. 94: 1-8, 1990.

• 5-22) Aaku, E. , Sorsai, T. , Wikstrdm, M.: Human immunoglobulin G potentiates super. oxide production induced by chemotactic peptides and causes degranulation in isolated human neutrophils. Biochim. Biophys. Acta 1052: 243-247, 1990.

• 5-23) Dahm, L. J. , Roth, R. A.: Differential effects of lithocholate on rat neutrophil activation. J. of Leukocyte Biol. 47: 551-560, 1990.
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• 5-24) Edwards, S. W. , Holden, C. S. , Humphreys, J. M. , Hart, C. A.: Granulocyte-macrophage colony-stimulating factor(GM-CSF) primes the respiratory burst and stimulates protein biosynthesis in human neutrophils. FEBS Letts. 256(1/2): 62-66, 1989.

• 5-25) 門田淳一, 広田正毅, 原 耕平・他:顆粒球コロニー形成刺激因子(G-CSF) の感染防御効果に関する研究(II). 感染症学雑誌 64(4):430-434, 1990.

• 5-25a) Hafstr6m, L. , Gyllenhammar, H. , Palmblad, J. , Ringertz, B.: Substance P activates and modulates neutrophil oxidative metabolism and aggregation. J. Rheumatol. 16: 1033-1037, 1989.

• 5-26) Hartfield, P. J. , Robinson, J. M.: Mg. ATP primes superoxide-generating responses in electro-permeabilized neutrophils. Biochem. Biophys. Res. Commun. 170(1): 194-200, 1990.

• 5-27) Axtell, R. A. , Sandborg, R. R. , Smolen, J. E. , Ward, P. A. , Boxer, L. A.: Exposure of human neutrophils to exogenous nucleotides causes elevation in intracellular calcium, transmembrane calcium fluxes and an alteration of a cytosolic factor. Blood 75(6): 1324-1332, 1990.

• 5-28) Naum, C. C. , Kaplan, S. S. , Basford, R. E.: Platelets and ATP prime neutrophils for enhanced O2 generation at low concentrations but inhibit O2 generation at high concentration. J. of Leukocyte Biol. 49: 83-89, 1991.
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• 5-29) Follin, P. , Dahlgren, C.: Altered O2/H2O2 production ratio by in vitro and in vivo primed human neutrophils. Biochem. Biophys. Res. Commun. 167(3): 970-976, 1990.
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• 5-30) Hancock, J. T. , Maly, F. -E. , Jones, O. T. G.: Properties of the superoxide-generating oxidase of B-lymphocyte cell line. Biochem. J 262: 373-375, 1989.

• 5-31) Maly, F. -E. , Urwyler, A. , Tengler, R. , Steinitz, M. , Golding, B. , De Weck, A. L.: Oxidative burst in human Epstein-Barr virus-transformed B-cell lines. Scand. J. Immunol. 32: 661-667, 1990.
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• 5-32) Hancock, J. T. , Henderson, L. M. , Jones, O. T. G.: Superoxide generation by EBV-transformed B lymphocytes. Immunol. 71: 213-217, 1990.

• 5-33) Leca, G. , Joly, F. , Vazquez, A. , Galanaud, P. , Ninio, E.: Paf-acether-induced superoxide anion generation in human B cell line. FEBS Letts. 269(1): 171-173, 1990.

• 5-34) Maly, F. -E.: The B lymphocyte: A newly recognized source of reactive oxygen species with immuno-regulatory potential. Free Rad. Res. Comms. 8(3): 143-148, 1990.

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• 5-36) Meier, B. , Radeke, H. H. , Selle, S. , Habermehl, G. G. , Resch, K. , Sies, H.: Human fibroblasts release low amount of reactive oxygen species in response to the potent phagocyte stimulants. Biol. Chem. Hoppe-Seyler 371: 1021-1025, 1990.

• 5-37) Meier, B. , Radeke, H. H. , Selle, S. , Raspe, H. -H. , Sies, H. , Resch, K. , Habermehl, G. G.: Human fibroblasts release reactive oxygen species in response to the treatment with synovial fluid from patients suffering from arthritis. Free Rad. Res. Commun. 8(3): 149-160, 1990.

• 5-38) Holland, J. A. , Pritchard, K. A. , Pappolla, M. A. , Wolin, M. S. , Rogers, N. I. , Stemerman, M. B.: Bradykinin induces superoxide anion release from human endothelial cells. J. of Cellul. Physiol. 143: 21-25, 1990.

• 5-39) Tiku, M. L. , Liesch, J. B. , Robertson, F. M.: Production of hydrogen peroxide by rabbit articular chondrocytes: Enhancement by cytokines. J. Immunol. 145(2): 699-696, 1990.

• 5-40) Shingu, M. , Yoshioka, K. , Nobunaga, M. , Motomatu, T.: C1q binding to human vascular smooth muscle cells mediates immune complex deposition and superoxide generation. Inflammation 13(5): 561-569, 1990.

第6章 白血球生成活性酸素の作用と促進剤

P.129 掲載の参考文献

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• 6-16) Cross, A. R. , Henderson, L. , Jones, O. T. G. , Delpiano, M. A. , Hentschel, J. , Acker, H.: Involvement of an NAD(P) Hoxidase as a pO2 sensor protein in the rat carotid body. Biochem. J. 272: 743-747, 1990.

• 6-17) Jonas, E. , Dwenger, A. , LueKen, B.: Simultaneous measurement of endothelial cell damage, elastase release and chemiluminescence response during interaction between polymorphonuclear leukocytes and endothelial cells. J. of Bioluminescence and Chemiluminescence 6: 19-17, 1991.

• 6-18) Khan, S. H. , Emerit, I. , Feingold. J.: Superoxide and hydrogen peroxide production by macrophages of New Zealand black mice. Free Rad. Biol. & Med. 8: 339-345, 1990.
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• 6-19) Peterhaus, E. , Jungi, T. W. , Stocker, R.: Autotoxicity and reactive oxygen in viral disease. Oxy-Radicals in Mol. Biol. and Pathol. (ed. Cerutti, P. A. , Fridovich, I. , McCord, J. M. , Alan R. Liss, Inc. ) 1988, p543-562.

• 6-20) Falk, R. J. , Terrell, R. S. , Charles, L. A. , Charles Jennette, J.: Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc. Natl. Acad. Sci. USA 87: 4115-4119, 1990.

• 6-21) 片岡真一, 谷村正信, 藤田幸利:尿中遊出多形核白血球のスーパーオキシド生成能. 医学のあゆみ 156(7):489-490, 1991.
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• 6-22) Shute, J. K. , Rimmer, S. J. , Akerman, C. L. , Church, M. K. , Holgate, S. T.: Studies of cellular mechanisms for the generation of superoxide by guineaっig eosinophils and its dissociation from granule peroxidase release. Biochem. Pharmacol. 40(9): 2013-2021, 1990.

• 6-23) Calhoun, W. J. , Bush, R. K.: Enhanced reactive oxygen species metabolism of airspace cells and air way inflammation follow antigen challenge in human asthma. J. Allergy Clin. Immunol. 86: 306-313, 1990.

• 6-24) Kumar, V. , Ganguly, N. K. , Sethi, A. K. , Anand, I. S. , Verma, J. , Wahi, P. L.: Role of oxygen free radicals generated by blood monocytes and neutrophils in the pathogenesis of rheumatic fever and rheumatic heart disease. J. Mol. Cell. Cardiol. 22: 645-651, 1990.
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• 6-25) Dularax, B. , Badesha, J. S. , Dieppe, P. A. , Elson, C. J.: Oxidative response of polymorphonuclear leukocytes to synovial fluid from patients with rheumatoid arthritis. Annals of the Rheumatic Dis. 49: 661-664, 1990.

• 6-26) Stevens, P. , Piazza, D. E.: Interleukin-2 increases the oxidative activity and induces migration of murine polymorphonuclear leukocytes in vivo. Int. J. Immunopharmac. 12(6): 605-611, 1990.

• 6-27) Ward, P. A. , Varani, J.: Mechanisms of neutrophil mediated killing of endothelial cells. J. of Leukocyte Biol. 48: 97-102, 1990.
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• 6-28) Shimada, Y. , Ito, H. , Kaji, K. , Fukuda, M.: Tumor necrosis factor reduces life span of human endothelial cells in vitro. Mechanism of Aging and Development. 55: 245-254, 1990.

• 6-29) Yamauchi, N. , Watanabe, N. , Kuriyama, H. , Neda, H. , Maeda, M. , Himeno, T. , Tsuji, Y.: Suppressive effect of intracellular glutathione on hydroxyl radical production induced by tumor necrosis factor. Int. J. Cancer 46: 884-888, 1990.
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• 6-29a) Laudanna, C. , Miron, S. , Berton, G. , Rossi, F.: Tumor necrosis factor-a/ca-chectin activates the O2-generating system of human neutrophils independently of the hydrolysis of phosphoinositides and the release of arachidonic acid. Biochem. Biophys. Res. Commun. 166(1): 308-315, 1990.

• 6-30) Das, V. N. , Padma, M. , Sagar, P. S. , Ramesh, G. , Koratkar, R.: Stimulation of free radical generation in human leukocytes by various agents including tumor necrosis factor is a calmodulin dependent process. Biochem. Biophys. Res. Commun. 167 (3): 1030-1036, 1990.

• 6-31) Tarnok Zs. T. I.: Direct stimulation of superoxide output in neutrophils by lipid A of Escherichia coli. Int. J. Tiss. Reaction 12: 47-52, 1990.

• 6-32) Wozniak, A. , McLennon, G. , Betts, W. H. , Murphy, G. A. , Scicchitano, R.: Activation of human neutrophils by substance P. Immunology 68: 359-364, 1989.

• 6-33) Marotti, T. , Sverko, V. , Hrsak, I.: Modulation of superoxide anion release from human polymorphonuclear cells by Met-and Leu-enkephalin. Brain Behavior and Immunol. 4: 13-22, 1990.

• 6-34) Marodi, L. , Kalmar, A. , Karmazsin, L.: Stimulation of the respiratory burst and promotion of bacterial killing in human granulocytes by intravenous immunog. lobulin preparations. Clin. Exp. Immunol. 79: 164-169, 1990.

• 6-35) Morikawa, M. , Abe, M. , Yamauchi, Y. , Inoue, M. , Tsuboi, M.: Priming effect of 2, 3-dibenzylbutane-1, 4-diol (mammalian lignan) on superoxide production in human neutrophils. Biochem. Biophys. Res. Commun. 168(1): 194-199, 1990.
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• 6-36) Sharmanov, A. T. , Aidarkanov, B. B. , Kurmangalinov, S. M.: Effect of vitamin E deficiency on oxidative metabolism and antioxidant enzyme activity of macrophages. Ann. Nutr. Metabolism 34: 143-146, 1990.

• 6-37) Revel, P. , Kraus, J-L. , Lederer, F.: Polymeric analogues of N-formyl peptides are potent activatiors of degranulation and superoxide production by human neutro. phils. Biochem. Biophys. Res. Commun. 171(1): 266-272, 1990.

• 6-38) Seifert, R. , Schultz, G. , Richter-Freund, M. , Metzger, J. , Wiesmuller, K-H. , Jung, G. , Bessler, W. G. , Hauschildt, S.: Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3 Cys-Ser-(Lys) 4. Biochem. J. 267: 795-802, 1990.

• 6-39) Hasegawa, E. , Takeshige, K. , Oishi, T. , Murai, Y. , Minakami, S.: 1-Methyl-4-phenylphridinium(MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxodation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 170(3): 1049-1055, 1990.

• 6-40) Maliszawska, M. , Jezieski, A. , Micera, G. , Gasiorowski, K. , Kozlowski, H.: Influence of dihydralazine on the generation of hydroxyl radicals by human granulocytes. Biomed. Biochim. Acta 5: 347-351, 1990.

• 6-41) Roth, R. A. , Hewett, J. A.: The cholestatic agent, a-naphtyl-isothiocyanate, stimulates superoxide release by rat neutrophils in vitro. Lab. Invest. 62(6): 736-741, 1990.

第7章 白血球活性酸素生成阻害剤

P.148 掲載の参考文献

• 7-1) Moon, D. G. , Van Der Zee, H. , Weston, L. K. , Gudewicz, P. W. , Fenton II, J. W. , Kaplan, J. E.: Platelet modulation of neutrophil superoxide anion production. Thrombosis and Haemostasis 63(1): 91-96, 1990.

• 7-2) Eklund, E. A. , Gabig, T. G.: Purification and characterization of a lipid thiobisester from human neutrophil cytosol that reversibly deactivates the O2-generating NADPH oxidase. J. Biol. Chem. 265(15): 8426-8430, 1990.
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• 7-3) Hecker, G. , Ney, P. , Schrdr, K.: Cytotoxic enzyme release and oxygen-centered radical formation in human neutrophils are selectively inhibited by E-type prostaglandins. N aunyn-Schmiedeberg's. Arch. Pharmacol. 341: 308-315, 1990.

• 7-4) Gordon, L. I. , Schmeichel, C. , Prachand, S. , Weitzman, S. A.: Inhibition of polymorphonuclear leukocyte oxidative metabolism by exogenous phospholipase C. Cellul. Immunol. 128: 503-515, 1990.

• 7-5) Shephard, E. G. , Anderson, R. , Rosen, O. , Myer, M. S. , Fridkin, M. , Strachan, A. F. , DeBeer, F. C.: Peptides generated from C-reactive protein by a neutrophil membrane protease. J. of Immunol. 145(5): 1469-1476, 1990.

• 7-6) Said, S. I.: Neuropeptides as modulators of injury and inflammation. Life Sci. 47: PL 19-21, 1990.

• 7-7) Matsuoka, T.: Asedative effect of dopamine on the respiratory burst in neonatal polymorphonuclear leukocytes. Pediatric Res. 28(1): 24-27, 1990.
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• 7-9) Ryan, S. F. , Ghassibi, Y. , Liau, D. E.: Effects of activated polymorphonuclear leukocytes upon pulmonary surfactant in vitro. Am. J. Respir. Cell Mol. Biol. 4: 33-41, 1991.

• 7-10) Combadiere, C. , Hakim, J. , Giroud, J. -P. , P6rianin, A.: Staurosporine, a protein kinase inhibitor, up-regulates the stimulation of human neutrophil respiratory burst by N-formyl peptides and platelet activating factor. Biochem. Biophys. Res. Commun. 168(1): 65-70, 1990.

• 7-11) DewaLd, B. , Thelen, M. P. , Wymann, M P. , Baggiolini, M.: Staurosporine inhibits the respiratory burst induces exocytosis in human neutrophils. Biochem. J. 264: 879-884, 1989.

• 7-12) Matsuno, T. , Orita, K. , Edashige, K. , Kobuchi, H. , Sato, E F. , Inouye, B. , Inoue, . M. , Utsumi, K.: Inhibition of active oxygen generation in guinea-pig neutrophils by biscoclaurine alkaloids. Biochem. Pharmacol. 39(7): 1255-1259, 1990.
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• 7-13) Savitha, G. , Panchanathan, S. , Salimath, B. P.: Capsaicin inhibits calmodulinmediated oxidative burst in rat macrophages. Cellular Signalling 2(6): 577-585, 1990.
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• 7-14) Leung-Tack, J. , Tavera, C. , Gensac, M. C. , Martinez, J. , Colle, A.: Modulation of phagocytosis-associated respiratory burst by human cystatin C. Experimental Cell Res. 188: 16-22, 1990.

• 7-15) Haisong, J. , Xiajie, L. , Baolu, Z. , Zhewu, H. , Wenjuan, X.: Scavenging effect of berbamine on active oxygen radicals in phorbol ester-stimulated human polymorphonuclear leukocytes. Biochem. Pharmacol. 39(11): 1673-1678, 1990.

• 7-16) Imamichi, T. , Nakamura, T. , Hayashi, K. , Kaneko, K. , Koyama, J.: Different effects of cinnamic acid on the O2 generation by guinea pig macrophages stimulated with a chemotactic peptide and immune complex. J. Pharmacobio-Dyn. 13: 344-352, 1990.
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• 7-17) Vasconcelles, M. J. , Weitzman, S. A. , Lee, S. N. , Prachard, S. , Gordon, L. I.: Inhibition of human polymorphonuclear leukcyte respiratory burst activity and aggregation by 6-ketocholestanol. Free Rad. Res. Comms. 8(3): 185-193, 1990.

• 7-18) Simons, J. M. , 'T Hart, B. A. , Vai Ching, T. R. A. M. Ip. , Van Dijk, H. , Labadie, R. P.: Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils. Free Rad. Biol. & Med. 8: 251-258, 1990.

• 7-19) Chiara, M D. , Bedoya, F. , Sorbino, F.: Cyclosporin A inhibits phorbol ester-induced activation of superoxide production in resident mouse peritoneal macrophages. Biochem. J. 264: 21-26, 1989.

• 7-20) Goldin, H. , Keisari, Y.: The effect of cyclosporine on macrophage oxidative burst potential during graft-versus-host reactions in mice. Transplantation 47(3): 548-552, 1989.
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• 7-21) Chiara, M. D. , Sobrino, F.: Modulation of the inhibition of respiratory burst in mouse macrophages by cyclosporin A. Immunology 72: 133-137, 1991.
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• 7-22) Cronstein, B. N. , Daguma, L. , Nicholas, D. , Hutchison, A. J. , Williams, M.: The adenosine neutrophil paradox resolved. J. Clin. Invest. 85: 1150-1157, 1990.

• 7-23) Schrier, D. J. , Lesch, M. E. , Wright, C. D. , Gilbersten, R. B.: The anti-inflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats. J. of. Immunol. 145(6): 1874-1879, 1990.

• 7-24) Walker, B. A. M. , Cunningham, T. W. , Freyer, D. R. , Todd, III, R. F. , Johnson, K. J. , Ward, P. A.: Regulation of superoxide responses of human neutrophils by adenine compounds. Lab. Invest. 61(5): 515-521, 1989.

• 7-25) Kubersky, S. M. , Hirschborn, R. , Broekman, M. J. , Cronstein, B. N.: Occupancy of adenosine receptors on human neutrophils inhibits respiratory burst stimulated by ingestion of complement-coated particles and occupancy of chemo-attractant but not Fc receptors. Inflammation 13(5): 591-599, 1989.

• 7-26) Tremoli, E. , Colli, S.: Dipyridamole inhibits superoxide anion generation by human neutrophils. Thrombosis and Haemostasis 59(2): 342, 1988.
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• 7-27) Auer, D. E. , Ng, J. C. , Seawright. A. A.: Superoxide production by stimulated equine polymorphonuclear leukocytes. J. Vet. Pharmacol. Therap. 13: 59-66, 1990.

• 7-28) Umeki, S.: Effects of non-steroidal anti-inflammatory drugs on human neutrophil NADPH oxidase in both whole cell and cell-free system. Biochem. Pharmacol. 40 (3): 559-564, 1990.
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• 7-29) Wakamura, K. , Ohtsuka, T. , Okamura, N. , Ishibashi, S. , Masayasu, H.: Mechanism for the inhibitory effect of a seleno-organic compound, Ebselen, and its analogues on superoxide anion production in guinea pig polymorphonuclear leukocytes. J. Pharmacobio-Dyn. 13: 421-425, 1990.
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• 7-30) 'THart, B. A. , Simons, J. M. , Knaan-Shanzer, S. , Bakker, N. P. M. , Labadie R. P.: Antiarthritic activity of the newly developed neutrophil oxidative burst agonist a pocynin. Free Rad. Biol. & Med. 9: 127-131, 1990.

• 7-31) Kanerud, L. , Hafstrom, I. , Ringertz, B.: Effect of sulphasalazine and suIphapyridine on neutrophil superoxide production. Annals of the Rheumatic Dis. 49: 296-300, 1990.

• 7-32) Vago, T. , Norbiato, G. , Baldi, G. , Chebat, E. , Bertora, P. , Bevilacqua, M.: Respiratory-burst stimulants desensitizeB-2 adrenoceptors on human polymorphonuclear leukocytes. Int. J. Tiss. Reac. 12(1): 53-58, 1990.

• 7-33) Kaneko, M. , Suzuki, K. , Furui, H. , Takagi, K. , Satake, T.: Effect of the new antiallergic compound ethyl 2-(4'-carboxy benzamido)-4-propionamido benzoate sodium salt on human neutrophil superoxide production. Arzneim. -Forsch. /Drug Res. 40(1) (Nr. 1): 91-94, 1990.

• 7-34) Rubin, R. P. , Thompson, R. H. , Naps, M. S.: Differential inhibition by nedocromil sodium of superoxide generation elicited by platelet activating factor in human neutrophils. Agents and Actions 31(3/4): 237-242, 1990.

• 7-35) Miesel, R. , Hartmann, H. -J. , Li, Y. , Weser, U.: Reactivity of active center analogs of Cu2 Zn2 superoxide dismutase on activated polymorphonuclear leukocytes. Inflammation 14(4): 409-419, 1990.

• 7-36) 倉繁 廸, 岡添陽子, 小林純郎, 小渕造嗣, 岩田 眞, 松野 剛, 内海耕造:好中球の活性酸素形成と Bifemelane Hydrochloride による阻害. 薬理と治療 17(10):4889- 4896, 1989.

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• 7-39) Hara, N. , Ichinose, Y. , Motohiro, A. , Kuda, T. , Aso, H. , Ohta, M.: Influence of chemotherapeutic agents on superoxide anion production by human polymorphonuclear leukocytes. Cancer 66: 684-688, 1990.
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• 7-40) Nielson, C. P. , Vestal, R. E. , Sturm, R. J. , Heaslip, R.: Effects of selective phos. phodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst. J. Allergy Clin. Immunol. 86: 801-808, 1990.

• 7-41) Simckowitz, L. , Foy, M. A. , Cragoe, E. J. Jr.: A role for Na+/Ca2+exchange in the generation of superoxide radicals by human neutrophils. J. Biol. Chem. 265(23): 13449-13456, 1990.

• 7-42) Nakano, Y. , Kawaguchi, T. , Sumitomo, J. , Takizawa, T. , Uetsuki, S. , Sugawara, M.: Novel inhibitors of superoxide anion generation, OPC-15160 and OPC-15161. The J. of Antibiotics 44(1): 52-58, 1991.

第8章 免疫・細胞付着と活性酸素

P.165 掲載の参考文献

• 8-1) Gougerot-Pocidalo, M. -A. , Roche, Y. , Fay, M. , Perianin, A. , Bailly, S.: Oxidative injury amplifies interleukin-1-like activity produced by human monocytes. Int. J. Immuno. Pharmac. 11(8): 961-969, 1989.

• 8-2) Duncan, D. D. , Lawrence, D. A.: Oxidatively stressed lymphocytes remain in Go/Gla on mitogenic stimulation. J. Biochem. Toxicol. 5(4): 229-235, 1990.

• 8-3) Dornand, J. , Gerber, M.: Inhibition of murine T-cell responses by anti-oxidants. Immunology 68: 384-391, 1989.
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• 8-4) Abramson, S. L. , Gallin, J. I.: IL-4 inhibits superoxide production by human mononuclear phagocytes. J. of Immunol. 144(2): 625-630, 1990.
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• 8-5) Chaudhri, G. , Clark, I. A. , Hunt, N. H. , Cowden, W. B. , Ceredig, R.: Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J. of Immunol. 137(8): 2646-2652, 1986.
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• 8-6) Chaudhri, G. , Clark, I. A.: Reactive oxygen species facilitate the in vitro and in vivo lipopolysaccharide-induced release of tumor necrosis factor. J. of Immunol. 143(4): 1290-1294, 1989.
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• 8-7) Schmalbach, T. K. , Borch, R. F.: Mechanism of diethydithiocarbamate modulation of murine bone marrow toxicity. Cancer Res. 50: 6218-6221, 1990.

• 8-8) 宮沢陽夫:過酸性リン脂質の産生とその毒性. 蛋白質核酸酵素 36(3):413-419, 1991.

• 8-9) Brewton, G. W. , Hersh, E. M. , Rios, A. , Mansell, P. W. A. , Hollinger, B. , Reuben, J. W.: A pilot study of diethyldithiocarbamate in patients with aquired immune deficiency syndrome(AIDS) and the AIDS-related complex. Life Sci. 45: 2509-2520, 1989.

• 8-10) Muller, F. , Rollag, H. , Froland, S. S.: Reduced oxidative burst responses in monocytes and monocyte-derived macrophages from HIV-infected subjects. Clin. Exp. Immunol. 82: 10-15, 1990.
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• 8-11) Halliwell, B. , Cross, C. E.: Reactive oxygen species, antioxidants, and aquired immunodeficiency syndrome. Arch. Intern. Med. 151: 29-31, 1991.

• 8-12) 丸山征郎:血管内皮細胞と凝固・線溶系. 医学のあゆみ 152(1):8-11, 1990.
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• 8-13) 玉谷卓也, 宮坂昌之:白血球の血管内皮細胞への接着. 最新医学 45(9):1806-1815, (1990).
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• 8-14) Lang, E. V. , Lang, J. H. , Lasser, E. C.: Adherence of granulocytes to nylon fibers. Thrombosis Res. 243-248, 1988.

• 8-15) Gallik, S. , Usami, S. , Jan, K. -M. , Chien, S.: Shear stress-induced detachment of human polymorphonuclear leukocytes from endothelial cell monolayers. Bio-rheology 26: 823-834, 1989.

• 8-16) Suematsu, M. , Oshio, C. , Miura, S. , Suzuki, M. , Houzawa, S. , Tsuchiya, M.: LuminoI-dependent photoemission from single neutrophil stimulated by phorbolester and calcium ionophore-Role of degranulation and myeloperoxidase. Biochem. Biophys. Res. Commun. 155(1): 106-111, 1988.

• 8-17) Ehlers, D. , Sakowski, I. , Mohrig, W.: Comparative studies on the adhesiveness of granulocytes of guinea pig and man. J. Comp. Physiol. B. 159: 481-489, 1989.

• 8-18) Larsen, C. G. , Anderson, A. O. , Joost, E. A. , Oppenheim, J. , Matsushima, K.: The neutrophil-activating protein(NAP-1) is also chemotactic for T lymphocytes. Science 243: 1464-1466, 1989.

• 8-19) Baggiolini, M. , Walz, A. , Kunkel, S. L.: Neutrophil-activating peptide-1/Interleukin 8, a novel cytokine that activates neutrophils. J. Clin. Invest. 84: 1045-1049, 1989.
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• 8-20) Patel, K. D. , Zimmerman, G. A. , Prescott, S. M. , McEver, R. P. , McIntyre, T. M.: Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. The J. of Cell Biol. 112: 749-759, 1991.

• 8-21) Varani, J. , Ginsburg, I. , Schuger, L. , Gibbs, D. F. , Bromberg, J. , Johnson, K. J. , Ryan, U. S. , Ward, P. A.: Endothelial cell killing by neutrophils, synergistic interaction of oxygen products and proteases. Am. J. of Pathol. 135(3): 435-438, 1989.

• 8-22) Nishida, M. , Kuzuya, T. , Hoshida, S. , Kim, Y. , Kitabatake, A. , Kamada, T. , Tada, M: Polymorphonuclear leukocytes induced vasoconstriction in isolated canine coronary arteries. Circulation Res. 66: 253-258, 1990.
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• 8-23) Broadley, C. , Hoover, R. L.: Ceruloplasmin reduces the adhesion and scavenges superoxide during the interaction of activated polymorphonuclear leukocytes with endothelial cells. Am. J. of Pathol. 135(4): 647-655, 1989.

• 8-24) Svensjd, E. , Erlansson, M. , Van den Bos, G. C.: Endotoxin-induced increase in leukocyte adherence and macromolecular permeability of postcapillary venules. Agents and Actions 29(1/2): 21-23, 1990.

• 8-25) Salvemini, D. , de Nucci, G. , Sneddon, J. M. , Vane, J. R.: Superoxide anions enhance platelet adhesion and aggregation. Br. J. Pharmacol. 97: 1145-1150, 1989.
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第9章 炎症と活性酸素

P.183 掲載の参考文献

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• 9-3) Masini, E. , Palmerani, B. , Gambassi, F. , Pistelli, A. , Giannella, E. , Occupati, B. , Ciuffi, M. , Sacchi, T. B. , Mannaioni, P. F.: Histamine release from rat mast cells induced by metabolic activation of polyunsaturated fatty acids into free radicals. Biochem. Pharmacol. 39(5): 879-889, 1990.
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• 9-8) Baker, M. S. , Lowther, D. A.: Oxidative damage to the key metabolic enzyme G3PDH occqrs in vitro after exposure to H2o2 and in an animal model of acute inflammatory arthritis. Pasadena Abst. 15. 6, 1990.

• 9-9) Vincent, F. , Brun, H. , Clain, E. , Ronot, X. , Adolphe, M.: Effect of oxygen-free radicals on proliferation kinetics of cultured rabbit articular chondrocytes. J. of Cellul. Physiol. 141: 262-266, 1989.

• 9-10) Iwasaki, Y. , Saegusa, Y. , Matsubara, T. , Hirohata, K.: Increased superoxide anion release from chondrocytes in response to Interleukin-1 and Interferons. J. Jpn. Orthop. Assoc. (日整会誌) 64: 976-982, 1990.

• 9-11) Uchida, N. , Asayama, K. , Dobashi, K. , Hayashibe, H. , Kato, K.: Antioxidant enzymes and lipid peroxide in blood in patients with Kawasaki Disease. Acta Paediatr. J pn. 32: 242-248, 1990.

• 9-12) Agaev, A. Y. , Nikolaev, A. V. , Abasov, B. , Kh. , Mamedov, L. A. , Zakharov, V. V. , Bashirov, E. A. , Bagirov, G. , S.: Experimental antioxidant therapy of purulent wounds. Bull. of Exp. Biol. Med. 108(7): 943-945, 1989.

• 9-13) Visner, G. A. , Wilson, J. , Ryan, U. , Nick, H. S.: Regulation of manganese superoxide dismutase in rat pulmonary endothel al cells by inflammatory mediators. Pasadena Abst. 14. 36, 1990.

• 9-14a) Garecki, M. , Beck, Y. , Hartman, Y. , Nimrod, A.: Recombinant superoxide dismutase in treatment of oxygen mediated diseases. Abstract of "5th Conference on Superoxide and Superoxide Dismutase" Jerusalem 17(22) Sept. , 1989, p50.

• 9-14b) Parizada, B. , Werber, M. , Nimrod, A.: Protective effect of human recombinant Mn-SOD in adjuvant arthritis and bleomycin-induced lung fibrosis. Jerusalem 17(22) Sept. , 1989, p173.

• 9-15) Wang, J. -P. , Teng, C-M.: Effect of antiinflammatory drugs on the cardiotoxin-induced hind-paw oedema in rats. J. Pharm. Pharmacol. 42: 842-845, 1990.
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• 9-16) Foschi, D. , Trabucchi, E. , Musazzi, M. , Castoldi, L. , DiMattia, D. , Radaelli, E. , Marazzi, M. , Franzini, P. , Berulusconi, A.: The effect of oxygen free radicals on wound healing. Int. J. Tiss. Reac. 10(6): 373-379, 1988.

• 9-17) Doherty, N. S. , Beaver, T. H. , Chan, K. Y. , Dinerstein, R. J. , Diekema, K A.: The antinociceptive activity of paracetamol in zymosan-induced peritonitis in mice. Br. J. Pham. Pharmacol. 101: 869-874, 1990.

• 9-18) Vaille, A. , J adot, G. , Elizagaray, A: Anti-inflammatory activity of various super-oxide dismutase on polyarthritis in the Lewis rat. Biochem. Pharmacol. 39(2): 247-255, 1990.

• 9-19) Oyanagui, Y. , Sato, S. , Okajima, T.: Suppressions of ischemic paw oedema in mice, rats and guinea pigs by superoxide dismutases from different sources. Free Rad. Res. Comms. 4(6): 385-396, 1988.

• 9-20) Schalkwijk, J. , van den Berg, W. B. , van de Putte, L. B. A. , J oosten, L. A. B. , van den Bersselaar, L.: Cationization of catalase, peroxidase, and superoxide dismutase. J. Clin. Invest. 76: 198-205, 1985.

• 9-21) Lindhart, W. E. , Zadravec, S. , Esterbauer, H. , Weybora, W. , Pfeiffer, K. P.: Staphylococcal arthritis-effects of superoxide dismutase on injected knee joints of rabbits. Free Rad. Res. Comms. 7(3-6): 325-333, 1989.

• 9-22) McIlwain, H. , Silverfield, J. C. , Cheatum, D. E. , Poiley, J. , Taborn, J. , Ignaczak, T. , Multz, C. V.: Intra-articular orgotein in osteoarthritis of the knee. The Am. J. of Med. 87: 295-300, 1989.

• 9-22a) Richard, Ph. , Roux, H. , Mattei, J. P. , Michelson, A. M. , J adot, G.: Etude clinique ouverte de la superoxyde dismutase liposomale dans la polyarthrite rhematoide severe. Therapie 44: 291-295, 1989.

• 9-22b) Conforti, A. , Caliceti, P. , Srtore, L. , Schiavon, O. , Veronese, F. , Velo, G. P.: Anti-inflammatory activity of monomethoxy polyethylen glycol superoxide dismutaseon adjuvant arthritis in rats. Pharmacol. Res. 23(1): 51-57, 1991.

• 9-23) Bartlett, R. R. , Gebert, V. V. , Kerekjarto, B. , Schleyerbach, R. , Tharwant, W. , Weithmann, K. V.: Substituted 3-pheny1-7H-thiazolo(3, 2-b) (1, 2, 4) triazin-7-ones as antiinflammatory agents with immunomodulating properties. Drug Exptl. Clin. Res. 15(11/12): 521-526, 1989.

• 9-24) Panetta, J. A. , Phillips, M. L. , Benslay, D. N. , Ho, P. P. K. , Towner, R. D. , Roush, M. E. , Clemens, J. A.: Two anti-oxidants, LY178002 and LY256548 as therapies for three unrelated degenerative disease. Pasadena Abst. 20. 17, 1990.

• 9-25) Parenti, C. , Costantino, L. , Di Bella, M.: Heteroarylalkanoic acids with possible antiinflammatory activities. Pharmazie. 45(H. 9): 680-681, 1990.

• 9-26) Zuurbier, K. W. M. , Bakknist, A. R. J. , Fokkens, R. H. , Nibbering, N. M. M. , Wever, R. , Muijsers, A. O.: Interaction of myeloperoxidase with diclofenac. Biochem. Pharmacol. 40(8): 1801-1808, 1990.

• 9-27) Mahlis, E. , Christophidis, N.: Modulation of iodination reaction in normal human neutrophils and in whole blood by penicillamine. congers and intracellular enzyme catalase and superoxide dismutase. Clin. and Exptl. Rheumatology 7: 365-371, 1989.

• 9-28) Broadley, C. , Hoover, R. L.: Ceruloplasmin reduces the adhesion and scavenges superoxide during the interaction of activited polymorphonuclear leukocytes with endothelial cell. Am. J. Pathol. 135(4): 647-655, 1989.

• 9-29) Higashiyama, H. , Egawa, H. , Iwata, S. , Wada, Y. , Shimahara, Y. , Sasada, M. , Mori, K. , Ogawa, K.: Impaired polymorphonuclear leukocyte function in patients undergoing hepatectomy. Br. J. Surg. 77: 1224-1228, 1990.

• 9-30) Muramoto, M. , Takeyama, H. , Taniguchi, M. , Hayakawa, T. , Katoh, K. , Ishikawa, S. , Shinagawa, N. , Yura, J. , Sinohara, R.: Therapeutic effect of superoxide dis・mutase in combination with an antimicrobial agent on peritonitis in rats. Pasadena Abst. 15. 24, 1990.

• 9-31) Broner, C. W. , Shenep, J. L. , Stidham, G. L. , Stokes, D. C. , Fairclough, D. , Schonbaum, G. R. , Rehg, J. E. , Hildner, W. K.: Effect of antioxidants in experimental Escherichia colisepticemia. Circulatory Shock 29: 77-92, 1989.

• 9-32) Nonaka, A. , Manabe, T. , Tobe, T.: Effect of a new synthetic free radical scavenger, 2-octadecyl ascorbic acid, on the mortality in mouse endotoxemia. Life Sci. 47: 1933-1939, 1990.
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• 9-33) Shook, L. A. , Pauly, T. H. , Marple, S. L. , Horstman, S. J. , Tai, H-H. , Bowdy, B Gillespie, M N.: Group B Streptococcus promotes oxygen radical-dependent thromboxane accumulation in young piglets. Pediatric Res. 27(4): 349-352, 1990.
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• 9-34) Stock, J. L. , Coferre, J. A. , Levine, P. H.: Effects of calcium-regulating hormonesand drugs on human monocyte chemiluminescence. J. Clin. Endocrinol and Metabolism 55(5): 956-960, 1982.

• 9-35) Fallon, M. , Silverton, S. , Snith, P. , Moskal, T. , Constantinescu, C. , Feldman, R. , Golub, E. , Shapiro, I.: The oxidative metabolism of isolated osteoclasts is regulated by calcitropic agents. J. of Bone and Mineral Res. 1(Suppl. 1), Abst. 1, 1986.

• 9-36) Garrett, I. R. , Boyce, B. F. , Oreffo, R. O. C. , Bonewald, L. , Poser, J. , Mundy, G. R.: Oxygen-derived free radicals stimulated osteoclastic bone resorption in rodent bone in vitro and in z/ivo. J. Clin. Invest. 85: 632-639, 1990.

• 9-37) Key, Jr. L. L. , Ries, W. L. , Taylor, R. G. , Hays, B. D. , Pitzer, B. L.: Oxygen derived free radicals in osteoclas+The specificity and location of the nitroblue tetrazolium reaction. Bone 11: 115-119, 1990.

• 9-38) Shapiro, I. M. , Tokuoka, T. , Forbes, E. , DeBolt, K. , Pacifici, M.: Oxygen radical formation by epiphyseal chondrocytes causes changes in cartilage collagen synthesis. Pasadena Abst. 1. 21, 1990

第10章 心臓での活性酸素

P.199 掲載の参考文献

• 10-1) Kloner, R. A. , Przyklenk, K. , Whittakar, P.: Delitorious effects of oxygen radicals in ischemia/reperfusion. Circulation 80(5): 1114-1126, 1989.

• 10-2) Engler, R. , Gilpin, E.: Can superoxide dismutase alter myocardial infarct size P. Circulation 79(5): 1136-1142, 1989.

• 10-3) Downey, J. M.: Free radicals and their involvement during long-term myocardial ischemia and reperfusion. Annu. Rev. Physiol. 52: 487-504, 1990.
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• 10-4) Reimer, K. A. , Murry, C. E. , Richard, V. J.: The role of neutrophils and free radicals in the ischemia-reperfusion heart-Why the confusion and controversy?. J. Mol. Cell Cardiol. 21: 1225-1239, 1989.
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• 10-5) Engler, R. I. , Schmid-Schenbein, G. W. , Pavelec, R. S.: Leukocyte capillary plugging in mycrocardial ischemia and reperfusion in the dog. Am. J. Pathol. 111: 98-111, 1983.

• 10-6) Forman, M. B. , Puett, D. W. , Virmani, R.: Endothelial and myocardial injury during ischemia and reperfusion. J. Am. College Cardiol. 13: 450-459, 1989.

• 10-7) Schaper, W. , Gdrge, G. , Winkler, B. , Schaper, J.: The collateral circulation of the heart. Progress in Cardiovas. Dis. 31(1): 57--77, 1988.

• 10-8) 三浦 伝:冠副血行路. 呼吸と循環 37(2):147-156, 1989.

• 10-9) Manfredi, J. P. , Holmes, W.: Purine salvage pathways in myocardium Ann. Rev. Physiol. 47: 691-705, 1985.

• 10-10) Gruber, H. E. , Hoffer, M. E. , McAllister, D. R. , Laikind, P. K. , Lane, T. A. , Schimid-Schoenbein, G. W. , Engler, R. L.: Increased adenosine concentration in blood from ischemic myocardium by AICA riboside. Circulation 80: 1400-1411, 1989.

• 10-11) Schrader, J. , Deussen, A. , Smolenski, R. T.: Adenosine is a sensitive oxygen sensor in the heart. Experientia 46: 1172-1175, 1990.
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• 10-12) Kaminski, P. M. , Proctor, K. G.: Actions of adenosine on nitrobluetetrazolium deposition and surface pH during intestinal reperfusion injury. Circul. Res. 66: 1713-1719, 1990.

• 10-13) Singh, J. , Garg, K. N. , Garg, D. , Lal, H.: Effect of adenosine and inosine on experimental myocardial infarction in rats. Indian J. of Expt'l. Biol. 26: 771-774, 1988.

• 10-14) Bowmer, C. J. , Yates, M. S.: Therapeutic potential for new selective adenosine receptor ligands and metabolism inhibitors. Trends in Pharmacol. Sci. 10(9): cover & 340-341, 1989.

• 10-15) Edlund, A. , Straat, E. , Henriksson, P.: Infusion of adenosine provokes myocardial ischaemia in patients with ischaemic heart disease. Clin. Physiol. 9: 307-311, 1989.
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• 10-16) Lynch, C. , Roddick, V. , Hutchins, P.: Altered microvascular response to adenosine in the spontaneously hypertensive rat. Microvas. Res. 38: 164-174, 1989.

• 10-17) Schneider, W. , Grune, T. , Sies, W. , Werner, A. , Gerber, G.: Nucleotide concentrations in hepatocytes during anoxia and roxygenation in presence of allopurinol and oxypurinol. Biomed. Biochim. Acta 48(2/3): S40-S43, 1989.

• 10-18) Sedlis, S. P. , Sequeira, J. M. , Altszuler, H. M.: Potentiation of the depressant effects of lysophosphatidyl choline on contractile properties of cultured cardiac myocytes by acidosis and superoxide radical. J. Lab. Clin. Med. 115: 203-216, 1990.

• 10-19) Starke-Reed, P. E. , Reid, M. B. , Tong, Mak, I. , Kramer, J. H. , Weglicki, W. B.: Oxidatiorl of cardiac cellular proteins and enzymes during acute oxidative stress. Pasadena Abst. 9. 25, 1990.

• 10-20) Mickle, D. A. G. , Li, R. , Wiesel, R. D. , Tumiati, L. C. , Wu, T-W.: Water-soluble antioxidant specificity against free radical injury using cultured human ventricular myocytes and fibroblasts and saphenous vein endothelial cells. J. Mol. Cell Cardiol. 22: 1297-1304, 1990.

• 10-21) Josephson, R. A. , Silverman, H. S. , Lakatta, E. G. , Stern, M. D. , Zweier, J. L.: Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes. J. of Biol. Chem. 266 (4): 2354-2361, 1991.
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• 10-22) Milner, P. , Ralevic, V. , Hopwood, A. M. , Feh6r, E. , Lincoln, 」. , Kirkpatrick, K. A. , Burnstock, G.: Unsaturated localisation of substance P and choline acetyltransferase in endothelial cells of rat coronary artery and release of substance P and acetylcholine during hypoxia. Experientia 45: 121-125, 1989.

• 10-23) Tanaka, M. , Hashimoto, Y. , Minezaki, K. , Shinozaki, Y. , Nakazawa, H. , Tsukamoto, H. , Komatsu, N. , Watanabe, K.: The fate of exogenously administered superoxide dismutase in myocardium and cultured endothelial cells. Pasadena Abst. 16. 6, 1990.

• 10-24) Hempel, S. L. , Haycraft, D. L. , Hoak, J. C. , Spector, A. A.: Reduced prostacyclin formation after reoxygenation of anoxic endothelium. Am. J. Physiol. 259: C738- C745, 1990.

• 10-25) Mehta, J. L. , Nicolini, F. A. , Lawson, D. L.: Sulfhydryl group in angiotensin converting enzyme inhibitors and superoxide radical formation. J. of Cardiovas. Pharmacol. 16: 847-849, 1990.

• 10-26) Constantin, M. , Bromont, C. , Fickat, R. , Massingham, R.: Studies on the activity of bepridil as a scavenger of free radical. Biochem. Pharmacol. 40(7): 1615-1622, 1990.
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• 10-27) Kalra, J. , Chaudhary, A. K. , Prasad, K.: Role of oxygen free radicals and pH on the release of cardiac lysosomal enzymes. J. Mol. Cell Cardiol. 21: 1125-1136, 1989.
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• 10-28) Zhang, Y. , Marcillat, O. , Giulivi, C. , Ernster, L. , Davies, K. J. A.: The oxidative inactivation of mitochondrial electron transport chain components and ATPase. J. Biol. Chem. 265(27): 16330-16336, 1990.

• 10-29) Mailer, K.: Superoxide radical as electron donor for oxidative phosphorylation of ADP. Biochem. Biophys. Res. Commun. 170(1): 59-64, 1990.
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• 10-30) Muscari, C. , Frascaro, M. , Guarnieri, C. , Caldarera, C. M.: Mitochondrial function and superoxide generation from submitochondrial particles of aged rat hearts. Biochim. Biophys. Acta 1015: 200-204, 1990.
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• 10-31) Haenen, G. R. M. M. , Veerman, M. , Bast, A.: Reduction of B-adrenoceptor function by oxidative stress in the heart. Free Rad. Biol. & Med. 9: 279-288, 1990

第11章 イヌとラットでの心臓虚血障害

P.216 掲載の参考文献

• 11-1) Nichols, W. W. , Mehta, J. L. , Donnelly, W. H. , Lawson, D. , Thompson, L. , ter Riet, M.: Reduction in coronary vasodilator reserve following coronary occlusion and reperfusion in anesthetized dog. J. Mol. Cell Cardiol. 20:943-954, 1988.
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• 11-2) Jeremy, R. W. , Becker, L. C.: Neutrophil depletion does not prevent myocardial dysfunction after brief coronary occlusion. J. Am. Coll. Cardiol. 13:1155-1163, 1989.
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• 11-3) Warner, K. G. , Khuri, S. F. , Marston, W. , Sharma, S. , Butler, M. D. , Assousa, S. N. , Saad, A. J. , Siouffi, S. Y. , Lavin, P. T.: Significance of the transmural diminution in regional hydrogen ion production after repeated coronary artery occlusions. Circul. Res. 64:616-628, 1989.

• 11-4) Lee, R. B. , Stewart, J. R. , Merrill, W. H. , Frist, W. H. , Hammon Jr, J. W. , Bender Jr, H. W.: Pharmacokinetics of superoxide dismutase during hypothermic cardiopulmonary bypass. Circulation 80 (Suppl. III), III 25-29, 1989.

• 11-5) Chudej, L. L. , Koke, J. R. , Bittar, N.: Evidence for transcytosis of exogenous superoxide dismutase and catalase from coronary capillaries into dog myocytes. Cytobiosis 63:41-53, 1990.

• 11-6) Abd-Elfattah, A. S. , Jessen, M. E. , Lekven, J. , Doherty III, N. E. , Brunsting, L. A. , Wechsler, A. S.: Myocardial reperfusion injury-role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury. Circulation 78 (Suppl. III): III 224-235, 1988.

• 11-7) Fincke, U. , Schneider, J. , Friderichs, E. , Giertz, H. , Flohe, L.: Enhanced myocardial salvage by combined treatment with reconbinant single-chain urokinase-type plasminogen activator and recombinant human superoxide dismutase in a canine coronary thrombosis model. Arzneim. -Forsch. /Drug Res. 38(I): Nr 1, 138-142, 1988.

• 11-8) Patel, B. S. , Jeroudi, M. O. , O'Neil, P. G. , Roberts, R. , Bolli, R.: Effect of human recombinant superoxide dismutase on canine myocardial infarction. Am. J. Physiol. 258:H369-H380, 1990.

• 11-9) Chi, L. , Tamura, Y. , Hoff, P. T. , Macha, M. , Gallagher, K. P. , Schork, M. A. , Lucchesi, B. R.: Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischema and reperfusion. Circul. Res. 64:665-675, 1989.

• 11-10) Tanaka, M. , Stoler, R. C. , FitzHarris, G. R. , Jennings, R. B. , Reimer, K. A.: Evidence against "early protection-delayed death" hypothesis of superoxide dismutase therapy in experimental myocardial infarction. Circul. Res. 67:636-644, 1990.

• 11-11) 小沢一仁, 小林 明, 山崎 昇:冠動脈結紮後再灌流時における心筋ミトコンドリア内フリーラジカルの変動. 脈管学 28(5):339-343, 1988.

• 11-12) Nejima, J. , Knight, D. R. , Fallon, J. T. , Uemura, N. , Manders, W. T. , Canfield, D. R. , Cohen, M. V. , Vatner, S. F.: Superoxide dismutase reduces reperfusion arrhythmias but fails to salvage regional function or myocardium at risk in conscious dogs. Circulation 79:143-153, 1989.
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• 11-13) Prasad, K. , Kalra, J. , Chaudhary, A. K. , Debnath, D.: Effect of polymorpho-nuclear leukocyte-derived oxygen free radicals and hypochlorous acid on cardiac function and some biochemical parameters. Am. Heart J. 119:538-550, 1990.

• 11-14) Lesnefsky, E. J. , Fennessey, P. M. , van Benthuysen, K. M. , McMurty, I. F. , Travis, V. L. , Horwitz, L. D.: Superoxide dismutase decreases early reperfusion release of conjugated dienes following regional canine ischemia. Basic Res. Cardiol. 84:191-196, 1989.

• 11-15) Kuzuya, T. , Hoshida, S. , Nishida, M. , Kim, Y. , Fuji, H. , Kitabatake, A. , Kamada, T. , Tada, M.: Role of free radicals and neutrophils in canine myocardial reperfusion injury. Cardiovas. Res. 23:323-330, 1989.

• 11-16) Tanabe, M. , Kito, G.: Effect of CV-3611. a new free radical scavenger, on ischemic heart failure in conscious beagle dogs. Jap. J. Pharmacol. 50:467-476, 1989.
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• 11-17) Mehta, J. L. , Lawson, D. L. , Nichols, W. W.: Attenuated caronary relaxation after reperfusion-Effects of superoxide dismutase and TxA2 inhibitor U63557A. Am. J. Physiol. 257:H1240-H1246, 1989.

• 11-18) Holzgrefe, H. H. , Buchanan, L. V. , Gibson, J. K.: Effects of U74006F, a novel inhibitor of lipid peroxidation, in stunned reperfused canine myocardium, J. of Cardiovas. Pharmacol. 15:239-248, 1990.

• 11-19) Maruyama, M. , Pieper, G. M. , Kalyanaraman, B. , Hallaway, P. E. , Hedlund, B. E. , Gross, G. J.: Effects of hydroxyethyl starch conjugated deferoxamine on myocardial functional recovery following coronary occlusion and reperfusion in dogs. J. of Cardiovas. Pharmacol. 17:166-175, 1991.

• 11-20) Babbitt, D. G. , Virmani, R. , Forman, M. B.: Intracoronary adenosine administered after reperfusion limits vascular injury after prolonged ischemia in the canine model. Circulation 80:1388-1399, 1989.
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• 11-21) Kusama, Y. , Bernier, M. , Hearse, D. J.: Singlet oxygen-induced arrhythmias. Circulation 80:1432-1448, 1989.
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• 11-22) Kusama, Y. , Bernier, M. , Hearse, D. J.: Photoactivation of porphyrins-Studies of reactive oxygen intermediates and arrhythmogenesis in the aerobic rat heart. Cardiovas. Res. 24:676-682, 1990.

• 11-23) 辰巳哲也, 朝山 純, 宮崎浩志, 山原康裕, 白山武司, 大森 斎, 井上大介, 中山雅夫: ラット心筋の低酸素化, 再酸化障害における reversibility の解明. 呼吸と循環 38 (12):1233-1239, 1990.

• 11-24) Bernier, M. , Manning, A. S. , Hearse, D. J.: Reperfusion arrhythmias-Dose-related protection by anti-free radical interventions. Am. J. Physiol. 256:H1344-H1352, 1989.
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• 11-25) Koerner, J. E. , Dage, R. C.: Delay of occurrence of reperfusion-induced ventricular fibrillation in the isolated rat heart with superoxide dismutase. J. of Cardiovas. Pharmacol. 16:461-467, 1990.

• 11-26) Johansson, M. H. , Deinum, J. , Marklund, S. L. , Sjoquist, P-O.: Recombinant human extracellular superoxide dismutase reduces concentration of oxygen free radicals in the reperfused rat heart. Cardiovas. Res. 24:500-503, 1990.

• 11-27) Chambers, D. J. , Astras, G. , Takahashi, T. , Manning, A. S. , Braimbridge, M. V. , Hearse, D. J.: Free radicals and cardioplegia-Organic anti-oxidants as additives to the St. Thomas' Hospital cardioplegic solution. Cardiovas. Res. 23:351-358, 1989.

• 11-28) Packer, L. , Valenza, M. , Leipala, J. , Serbinova, E. , Kagan, V. , Starke-Reed, P.: Myocardial ischemia-reperfusion injury mechanism of protection by L-propionyl carnitine. Pasadena Abst. 10. 30 1990.

• 11-29) Tada, H. , Kutsumi, Y. , Misawa, T. , Shimamoto, N. , Nakai, T. , Miyabo, S.: Effects of pretreatment with 2-O-octadecylascorbic acid. a novel free radical scavenger, on reperfusion-induced arrhythmias in isolated perfused rat hearts. J. of Cardiovas. Pharmacol. 16:984-991, 1990.

• 11-30) Powell, S. R. , Hall, D.: Use of salicylate as a promotor of ・OH formation in isolated ischemic rat hearts. Free Rad. Biol. & Med. 9:133-141, 1990.

• 11-31) Appelbaum, Y. J. , Kuvin. J. , Borman, J. B. , Uretzky, G. , Chevion, M.: The protective role of neocuproine against cardiac damage in isolated perfused rat hearts. Free Red. Biol. & Med. 8:133-143, 1990.

• 11-32) Pi, X-J. , Chen, X.: Captopril and Ramiprilat protect against free radical injury in isolated working rat hearts. J. Mol. Cell Cardiol. 21:1261-1271, 1989.
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• 11-33) Baker, J. E. , Kalyanaraman, B.: Ischemia-induced changes in myocardial paramagnetic metabolites. FEBS Letts. 244(2):311-314, 1989.

• 11-34) Matsui, Y. , Hashimoto, H. , Tsukamoto, H. , Okumura, K. , Ito, T. , Ogawa, K. , Satake, T.: Disappearance and appearance of isoenzymes of creatine kinase, lactate dehydrogenase and aspartate aminotransferase in the myocardium undergoing infarction. Cardiovas. Res. 23:249-253, 1989.

• 11-35) Brown, J. M. , White, C. W. , Terada, L. S. , Grosso, M. A. , Shanley, P. F. , Mulvin, D. W. , Banerjee, A. , Whitman, G. J. R. , Harken, A. H. , Repine, J. E.: Interleukin-I pretreatment decreases ischemia/reperfusion injury. Proc. Natl. Acad. Sci. USA 87:5026-5030, 1990.

• 11-36) Bensard, D. D. , Brown, J. M. , Anderson, B. O. , Banerjee, A. , Shanley, P. F. , Grosso, M. A. , Whitman, G. J. R. , Harken, A. H.: Induction of endogenous tissue antioxidant enzyme activity attenuates myocardial reperfusion injury. J. of Surgical Res. 49:126-131, 1990.

• 11-37) Watanabe, N. , Inoue, M. , Morino, Y.: Inhibition of postischemic reperfusion arrhythmias by an SOD derivative that circulates bound to albumin with prolonged in vivo half-life. Biochem. Pharmacol. 38(20):3477-3483, 1989.
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• 11-38) Sjoquist, P. -O. , Marklund, S.: Effects of endothelial bound EC-SOD type C on myocardial damage in reperfused ischemic rat hearts. Pasadena Abst. 16. 26, 1990.

• 11-39) Zelck V. , Janichen, F. , Karnstedt, U.: Influence of superoxide dismutase and Iloprost on the ischemia induced arrhythmias and post-ischemic myocardial function. Pasadena Abst. 16. 31, 1990.

• 11-40) Evsev'eva, M. V. , Shinkarenko, V. S. , Didenko, V. V. , Meerson, F. Z.: Limiting the area of ischemic necrosis by the antioxidant Ionol. Bulletin of Expt'l Biol. & Med. 108:1082-1085, 1989.

• 11-41) Petty, M. , Grisar, J. M. , Dow, J. , De Jong, W.: Effects of an a-tocopherol analogue on myocardial ischaemia and reperfusion injury in rats. Eur. J. of Pharmacol. 179:241-242, 1990.
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• 11-42) Hermenegildo, C. , Nies, E. , Monsalve, E. , Puertas, F. J. , Higueras, V. , Romero, F. J.: Some aspects of cardiac antioxidant defence: Ebselen (PZ51)treatment increases glutathione peroxidase activity in the heart. Biochem. Soc. Transactions 635th Meeting, Aberdeen 1990, p1193-1994.

第12章 ウサギ・ブタ・ヒトの心臓虚血障害と心移植

P.230 掲載の参考文献

• 12-1) Shlafer, M. , Myers, C. L. , Adkins, S.: Mitochondrial hydrogen peroxide generation and activities of glutathione peroxide and superoxide dismutase following global ischemia. J. Mol. Cell Cardiol. 19:1195-1206, 1987.

• 12-2) Schlafer, M. , Brosamer, K. , Forder, J. R. , Simon, R. H. , Ward, P. A. , Grum, C. M.: Cerium chloride as a histochemical marker of hydrogen peroxide in reperfused ischemic hearts. J. Mol. Cell Cardiol. 22:83-97, 1990.

• 12-3) Omar, B. A. , Gad, N. M. , Jordan, M C. , Striplin, S. P. , Russell, W. J. , Downey, J. M. , McCord, J. M.: Cardioprotection by Cu, Zn-superoxide dismutase is lost at high doses in the reoxygenated heart. Free Rad. Biol. & Med. 9:465-471, 1990.
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• 12-4) Omar, B. A. , McCord, J. M.: The cardioprotective effect of Mn-superoxide dismutase is lost at high doses in the postischemic isolated rabbit heart. Free Rad. Biol. & Med. 9:473-478, 1990.
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• 12-5) McCord, J. M. , Omar, B. A.: Mechanism of ischemia/reperfusion injury. Pasadena Abst. 10. 1, 1990.

• 12-6) Mousa, S. A. , Brown, R. , Thoolen, M. J. M. , Smith, R. D.: Evaluation of the effect of azapropazone on neutrophil migration in regional myocardial ischemia/reperfusion injury in rabbits. Br. J. Pharmacol. 100:379-382, 1990.

• 12-7) Adachi, T. , Miura, T. , Noto, T. , Ooiwa, H. , Ogawa, T. , Tsuchida, A. , Iwamoto, T. , Goto, M. , Iimura, O.: Does verapamil limit myocardial infarct size in a heart deficient in xanthine oxidase? Clin. and Expt'l. Pharmacol. and Physiol. 17:769-779, 1990.

• 12-8) 羽鳥信郎, 瓜生田曜造, 吉津 博, 栗田 明, 田中 勧: Superoxide dismutase およびcatalaseの投与法に関する検討. 循環器科 26:24-29, 1989.

• 12-9) Buchwald, A. , Klein, H. H. , Lindert, S. , Pich, S. , Nebendahl, K. , Wigand, V. , Kreuzer, H.: Effect of intracoronary superoxide dismutase on regional function in stunned myocardium. J. of Cardiovas. Pharmacol. 13:258-264, 1989.

• 12-10) Clement, R. , Das, D. K. , Engelman, R. M. , Otani, H. , Bandhyopadhyay, D. , Hoory, S. , Antar, M. , Rousou, J. A. , Breyer, R. H. , Prasad, M. R.: Role of nonsteroidal anti-inflammatory agent, ibuprofen, in coronary revascularization after acute myocardial infarction. Basic Res. in Cardiol. 85:55-70, 1990.
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• 12-11) Crawford, M. H. , Grover, F. L. , Kolb, W. P. , McMahan, C. A. , O'Rourke, R. A. , McManus, L. M. , Pickard, R. N.: Complement and neutrophil activation in the pathogenesis of ischemic myocardial injury. Circulation. 78:1449-1458, 1988.

• 12-12) Becker, B. F. , Reinholz, N. , Ozgelik, T. , Leipert, B. , Gerlach, E.: Uric acid as radical scavenger and anti-oxidant in the heart. Pfluger Arch. 415:127-135, 1989.

• 12-13) Lee, R. T. , Lee, T. H. , Poole, W. K. , Gustafson, N. , Stone, P. H. , Jaffe, A. S. , Muller, J. E. , Sobel, B. E. , Roberts, R. , Braunwald, E.: Rate of disappearance of creatine kinase-MB after acute myocardial infarction-Clinical determinants of variability. Am. Heart J. 116:1493-1499, 1988.
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• 12-14) Paterson, J. R. , Oldroyd, K. G. , Rumley, A. G. , Eteiba, H. , Rae, H. P. , Hutton, I. , Cobbe, S. M.: Free radical activity during percutaneous trans-luminal coronary angioplasty. Biochem. Soc. Transactions (635th Meeting) 18:1183-1184, 1990.

• 12-15) Weitz, Z. W. , Birnbaum, A. J. , Zarling, E. J. , Skosey, J. L.: Breath pentane in acute myocardial infarction. Pasadena Abst. , 1990.

• 12-16) Ferrari, R. , Alfieri, O. , Curello, S. , Ceconi, C. , Cargnoni, A. , Marzollo, P. , Pardini, A. , Caradonna, E. , Visiol, O.: Occurrence of oxidative stress during reperfusion of the human heart. Circulation 81:201-211, 1990.

• 12-17) Gharazozloo, F. , Melendez, F. J. , Hein, R. A. , Shemin, R. J. , Disesa, V. J. , Cohn, L. H.: The effect of superoxide dismutase and catalase on the extended preservation of the ex vivo heart for transplantation. J. Thorac. Cardiovas. Surg. 95:1008-1013, 1988.

• 12-18A) Bando, K. , Seno, Y.: Oxygen derived free radical damage in canine heart transplantation. J. Surg. Res. 46:152-156, 1989.

• 12-18B) 妹尾嘉昌, 中山頼和:開心術心筋保護における r-h-SOD 臨床応用. フリーラジカル の臨床 Vol. 5. (近藤元治・監修, 大柳善彦, 吉川敏一・編), 日本医学館, 1990, p113- 119.

• 12-19) Lazar, H. L. , Yang, X. , Rivers, S. , Stockwell, D. , Shemin, R. J.: Superiority of substrate enhancement over oxygen free-radical scavengers during extended periods of cold storage for cardiac transplantation. Surgery 108:423-430, 1990.
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• 12-20) Kimura, Y. , Iyengar, J. , Engelman, R. M. , Das, D. K.: Prevention of myocardial injury in expermental coronary revascularization following ischemic arrest by a novel antimflammatory drug, ONO-3144. J. of Cardiovasc. Pharmacol 16:992-999, 1990.

• 12-21) Dworkin, G. H. , Abd-Elfattah, A. S. , Yeh, Jr. T. , Wechsler, A. S.: Efficacy of recombinant-derived human superoxide dismutase on porcine left ventricular contractility after normothermic global myocardial ischemia and hypothermic cardioplegic. arrest. Circulation 82(suppl. IV, VI):359-366, 1990.

• 12-22) Julia, P. L. , Buckberg, G. D. , Acar, C. , Partington, M. T. , Sherman, M P.: Studies of controlled reperfusion after ischemia J. Thorac. Cardiovasc. Surg. 101:303-313, 1991.
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第13章 呼吸器系での活性酸素

P.247 掲載の参考文献

• 13-1) Calhoun, W. J. , Salisbury, S. M.: Heterogeneity in cell recovery and superoxide production in buoyant density-defined subpo pulations of human alveolar macrophages from healthy volunteers and sarcoidosis patients. J. Lab. Clin. Med. 114:682-690, 1989.

• 13-2) Wallaert, B. , Lassalle, P. , Fortin, F. , Aerts, C. , Bart, F. , Fournier, E. , Voisin, C.: Superoxide anion generation by alveolar inflammatory cells in simple pneumoconiosis and in progressive massive fibrosis of nonsmoking coal workers. Am. Rev. Respir. Dis. 141:129-133, 1990.
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• 13-3) Nakashima, J. M. , Hyde, D. M. , Giri, S. N.: Dose-related effects of enzyme generated oxidants on the biochemistry and morphology of the hamster lung. Toxicology 58:249-266, 1989.
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• 13-4) Nagase, T. , Fukuchi, Y. , Jo, C. , Teramoto, S. , Uejima, Y. , Ishida, K. , Shimizu, T. , Orimo, H.: Endothelin-1 stimulates arachidonate 15-lipooxgenase activity and oxygen radical formation in the rat distal lung. Biochem. Biophys. Res. Commun. 168(2):485-489, 1990.

• 13-5) Warren, J. S. , Yabroff, K. R. , Mandel, D. M. , Johnson, K. J.: Role of O-2 in neutrophil recruitment into sites of dermal and pulmonary vasculitis. Free Rad. Biol. & Med. 8:168-172, 1990.

• 13-6) Keen, R. R. , Stella, L. A. , Flanigan, D. P. , Lands, W. E. M.: Differences between arterial and mixed venous levels of plasma hydroperoxides following major thoracic and abdominal operations. Free Rad. Biol. & Med. 9:485-494, 1990.

• 13-7) Guice, K. S. , Oldham, K. T. , Caty, M. G. , Johnson, K. J. , Ward, P. A.: Neutrophil-dependent, oxygen-radical mediated lung injury associated with acute pancreatitis. Annals of Surgery 210(6):740-747, 1989.
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• 13-8) Adams, Jr, J. D. , Heins, M. C. , Yost, G. S.: 3-methylindole inhibits lipid peroxidation. Biochem. Biophys. Res. Commun. 149(1):73-78, 1987.

• 13-9) Slosman, D. O. , Costabella, P. M. , Roth, M. , Werlen, G. , Polla, B. S.: Bleomycin primes monocytes-macrophages for superoxide production. Eur. Respir. J. 3:772-778, 1990.
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• 13-10) Kehrer, J. P. , DiGiovanni, J.: Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene. Toxicol. Letters 52:55-61, 1990.

• 13-11) Nowak, D. , Ruta, U.: Nicotine inhibits α-1-proteinase inhibitor inactivation by oxidants derived from human polymorphonuclear leukocytes. Exp. Pathol. 38:249-255, 1990.

• 13-12) Berisha, H. , Foda, H. , Sakakibara, H. , Trotz, M. , Pakbaz, H. , Said, S. I.: Vasoactive intestinal peptide prevents lung injury due to xanthine/xanthine oxidase. Am. J. Physiol. 259:L151-115, 1990.
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• 13-13) Cantin, A. M. , Fells, G. A. , Hubbard, R. C. , Crystal, R. G: Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract. J. Clin. Invest. 86:962-971, 1990.
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• 13-14) Warburton, D. , Buckley, S. , Cosico, L. , Forman, H. J.: Sublethal oxidant injury inhibits signal transduction in rat type II pneumocytes. Am. J. Physiol. 257:L217-220, 1989.
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• 13-15) Weber, H. , Heilmann, P. , Meyer, B. , Maier, K. L.: Effect of canine surfactant protein(SP-A)on the respiratory burst of phagocytic cells. FEBS Letts. 270(1/2):90-94, 1990.

• 13-16) Dikshit, M. , Srivastava, R. , Srimal, R. C.: Role of free radicals in pulmonary thromboembolism in mice. Thrombosis Res. 55:549-557, 1989.

• 13-17) Harabin, A. L. , Braisted, J. C. , Flynn, E. T.: Response of antioxidant enzymes to intermittent and continuous hyperbaric oxygen. J. Appl. Physiol. 69(1):328-335, 1990.
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• 13-18) Schneider, J. , Matthiesen, T.: The prostacyclin analogue taprostene and r-h-SOD increase the permanent survival rate of endotoxemic rats. Life Sci. 46:1421-1426, 1990.

• 13-19) Schneider, J. , Friderichs, E. , Heintze, K. , Flohe, L.: Effects of r-h-SOD on increased lung vascular permeability and respiratory disorder in endotoximic rats. Circulatory shock 30:97-106, 1990.

• 13-20) Thibeanlt, D. W. , Beringer, T. , Mabry, S. , Rezaiekhaligh, M.: Prevention of chronic pulmonary oxygen toxicity in young rats with liposome encapsulated catalase administered intratracheally. Circulation 38(1):206A, 1990.

• 13-21) Walther, F. J. , Wade, A. , Warburton, D. , Forman, H. J.: Augmentation of catalase activity in type II pneumocytes. Circulation 38(1):207A, 1990.

• 13-22) 中神啓仁, 稲村 恵, 中野雄司, 小林洋四郎:モルモット肺障害に及ぼす liposome化 r-h-SOD の影響. 日薬理誌 (Folia pharmacol. Japon) 97:41-49, 1991.

• 13-23) Hazinski, T. A. , France, M. , Kennedy, K. A. , Hansen, T. N.: Cimetidine reduces hyperoxic lung injury in lambs. J. Appl. Physiol 65:1579-1585, 1988.
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• 13-24) Haynes Jr, J. , Seibert, A. , Bass, J. B. , Taylor, A. E.: U74500A inhibition of oxidant-mediated lung injury. Am. J. Physiol 259:H144-148, 1990.
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• 13-25) Zheng, H. , Cowley, J. J. , Chan, J. C. , Hoffmann, H. , Hatherill, J. R. , Ishizaka, A. , Raffin, T. A.: Attenuation of tumor necrosis factor-induced endothelial cell cytotoxicity and neutrophil chemiluminescence. Am. Rev. Respir. Dis, 142:1073-1078, 1990.

• 13-26) Klausner, J. M. , Paterson, I. S. , Kobzik, L. , Valeri, C. R. , Shepro, D. , Hechtman, H. B.: Oxygen free radicals mediate ischemia-induced lung injury. Surgery 105:192-199, 1989.
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• 13-27) Forman, H. J. , Skelton, D. C.: Protection of alveolar macrophages from hyperoxia by y-glutamyl transpeptidase. Am. J Physiol. 259:L1O2-107, 1990.

• 13-28) Randall, R. , Panus, P. C. , Holm, B. A. , Engstrom, P. C. , Freeman, B. A. , Matalon, S. S.: Endogenous xantine oxidase-derived O2 metabolites inhibit surfactant metabolism. Am. J. Physiol. 259:L328-334, 1990.

• 13-29) Stelzner, T. J. , O'Brien, R. F. , Sato, K. , Weil, J. V.: Hypoxia-induced increases in pulmonary transvascular protein escape in rats. J. Clin. Invest. 82:1840-1847, 1988.
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• 13-30) Oyanagui, Y.: Physiological regulation of vascular permeability by endogenous glucocorticoids and active oxygen. Inflammation 7(1):81-89, 1983.
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• 13-31) Oyanagui, Y. , Suzuki, S.: Vasoregulin, a glucocorticoid-inducible vascular permeability inhibitory protein. Agents and Actions 17(3/4):270-277, 1985.

• 13-32) Masukawa, T. , Tochino, Y.: Circadian periodicity in the resistance to hypoxia in mice. The Japanese J. of Pharmacol. (The 64th Annual Meeting, Kobe) O-405, 1991.

• 13-33) Wright, C. D. , Low, J. E.: Formation of chloramine derivatives of histamine-Role of histamine chloramines in bronchoconstriction. Biochem. Biophys. Res. Commun. 165(3):1018-1026, 1989.
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• 13-34) Sedgwick, J. B. , Geiger, K. M. , Busse, W. W.: Superoxide generation by hypodense eosinophils from patients with asthma. Am. Rev. Resp. Dis. 142:120-125, 1990.
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• 13-35) Chanez, P. , Dent, G. , Yukawa, T. , Barnes, P. J. , Chung, K. F.: Generation of oxygen free radicals from blood eosinophils from asthma patients after stimulation with PAF or phorbol ester. Eur. Respir. J. 3:1002-1007, 1990.
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• 13-36) 大田 顕:活性酸素について. 日本医事新報 3491:66, 1991.

• 13-37) Lai, Y. -L.: Oxygen radicals in capsaicin-induced bronchoconstriction. J. Appl. Physiol. 68(2):568-573, 1990.
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• 13-38) Ho, P. P. K. , Wang, L. Y. , Tower, R. D. , Hayes, S. J. , Pollock, D. , Bowling, N. , Wyss, V. , Panetta, J. A.: Cardiovascular effect and stimulus-dependent inhibition of superoxide generation from human neutrophils by Tibenelast (LY186655). Biochem. Pharmacal. 40(9):2085-2092, 1990.

• 13-39) Kurosawa, M. , Ishizuka, T. , Kobayashi, S. , Nakano, M.: Effects of antiallergic drugs on superoxide anion generation from activated human alveolar macrophages measured by chemiluminescence method. Arzneim. -Forsch. /Drug Res. 41(1):47-51, 1991.

第14章 肝臓・膵臓での活性酸素

P.263 掲載の参考文献

• 14-1) Harata, J. , Nagata, M. , Sasaki, E. , Ishiguro, I. , Ohta, Y. , Murakami, Y.: Effect of prolonged alcohol administration on activities of various enzymes scavenging activated oxygen radicals and lipid peroxide level in the liver of rats. Biochem, Pharmacol. 32 (11): 1795-1798, 1983.
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• 14-2) 池田有成, 黒川 清・他: HCV 抗体陽性自己免疫性肝炎患者血清中に検出される抗 superoxide dismutase 抗体. 肝臓 31(9):103-104, 1990.

• 14-3) 康山俊学, 佐々木 博・他:急性四塩化炭素肝障害ラットにおける肝組織中の Cu, Zn superoxide dismutase の免疫組織化学的研究. 肝臓 31 (1):69-79, 1990.

• 14-4) Shiratori, Y. , Tanaka, M. , Hai, K. , Kawase, T. , Shiina, S. , Sugimoto, T.: Role of endotoxin-responsive macrophages in hepatic injury. Hepatology 11: 183-192, 1990.

• 14-5) Inselmann, G. , Hannemann, J. , Baumann, K.: Cyclosporin A induced lipid peroxidation and influence on glucose-6-phosphatase in rat hepatic and renal microsomes. Res. Commun. in Chem. Pathol. and Pharmacol. 68 (2): 189-203, 1990.
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• 14-6) Vani, M. , Reddy, G. P. , Reddy, G. R. , Thyagaraju, K. , Reddanna, P.: Glutathione-S-transferase, superoxide dismutase, xanthine oxidase, catalase, glutathione peroxidase and lipid peroxidation in the liver of exercised rats. Biochem. Int'l 21 (1): 17-26, 1990.

• 14-7) Parascandola, J.: Dinitrophenol and bioenergetics: ahistorical perspective. Mol. and Cellul. Biochem. 5 (1-2): 69-76, 1974.

• 14-8) Sohal, R. S. , Svensson, I. , Brunk, U. T.: Hydrogen peroxide production by liver mitochondria in different species. Mechanisms of Ageing and Development 53: 209-215, 1990.
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• 14-9) Woods, J. S. , Calas, C. A. , Aicher, L. A. , Robinson, B. H. , Mailer, C.: Stimulation of porphyrinogen oxidation by mercuric ion (1) . Mol. Pharmacol. 38: 253-260, 1990

• 14-10) Woods. J. S. , Calas, C. A. , Aicher. L. D.: Mol. Pharmacol. 38(II): 261-266, 1990
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• 14-11) Corbisier, P. , Raes, M. , Michielis, C. , Pegeolet, E. , Houbion, A. , Delaive, E. , Remacle, J.: Respiratory activity of isolated rat liver mitochondria following in vitro exposure to oxygen species. Mechanisms of Ageing and Development 51: 249-263, 1990.

• 14-11a) Narayanaswami, V. , Sies, H.: Oxidative damage to mitochondria and protection by Ebselen and other antioxidants. Biochem. Pharmacol. 40 (7): 1623-1629 1990.

• 14-12) Rundgren, M. , Harder, S. , Nelson, S. D. , Andersson, B. S.: Oxidant-induced changes in the cellular energy homeostasis. Biochem. Pharmacol. 40 (2): 239-243, 1990.
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• 14-13) Cheng, L. L. , Collier, D. C. , Wilkie, D.: Effect of antioxidants on the mitochondrial activity and toxicity of the cancer drug methylglyoxal bis (guanyl hydrazone) in yeast and mammalian cells. Cancer Letts. 51: 213-220, 1990.

• 14-14) Oyanagui, Y. , Sato, N. , Hagihara, B.: Spectrophotometric analysis of cytochromes in rat liver during carcinogenesis. Cancer Res. 34: 458-462, 1974.
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• 14-15) Oyanagui, Y. , Hagihara, B.: Active oxygen production of mitochondria from tumors and liver of adrenalectomized rodents "Superoxide and Superoxide Dismutase in Chemistry. Biology and Medicine" . (ed. Rotilio. G. ), Elsevier Sci. Publishers B. V. 1986, p 429-431.

• 14-16) Giri, S. N. , Misra, H. P.: Fate of SOD in mice following oral route of administration. Medical Biol. 62: 285-289, 1984

• 14-17) Nakae, D. , Yoshiji, H. , Yamamoto, K. , Maruyama, H. , Kinugasa, T. , Takashima, Y. , Denda, A. , Konishi, Y.: Influence of timing of administration of liposome-encapsulated SOD on its prevention of acetaminophene-induced liver cell necrosis in rats. Acta Pathol. Jpn. 40: 568-573, 1990.

• 14-18) Kaneo, Y. , Fujihara, Y. , Tanaka, T. , Kozawa, Y. , Mori, H. , Iguchi, S.: Intrahepatic delivery of glutathione by conjugation to dextran. Pharmaceut. Res. 6 (12): 1025-1031, 1989.

• 14-19) Nakae, D. , Yamamoto, K. , Yoshiji, H. , Kinugasa, T. , Maruyama, H. , Farber, J. L. , Konishi, Y.: Liposome-encapsulated SOD prevents liver necrosis induced by acetaminophen. Am. J. of Pathol. 136 (4): 787. -795, 1990.

• 14-20) Petersen, E. N.: Pharmacological effects of diethyldithiocarbamic acid methyl ester, the active metabolite of disulfiram? Eur. J. of Pharmacol. 166: 419-425, 1989
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• 14-21) Ishiyama, H. , Ogino, K. , Shimomura, Y. , Kanbe, T. , Hobara, T.: Hepatotoxicity of diethyldithiocarbamate ill rats. Pharmacol. & Toxicol. 67: 426-430, 1990.

• 14-22) Lauriault, V. V. , McGirr, L. G. , Wong, W. W. C. , O'Brien, P. J.: Modulation of benzoquinone-induced cytotoxicity by diethyldithiocarbamate in isolated hepatocytes. Arch. of Biochem. Biophys. 282 (1): 26-33, 1990

• 14-23) Garcia-Valdecasas, J. C. , Cugat, E. , Almenara, R. , Grande, L. , Angas, J. , Fuster, J. ,
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• 14-24) 水田哲明, 石原敬夫:ラット肝虚血再灌流障害に対する SOD の効果. 肝臓 31 (9): 101-102, 1990.

• 14-25) Castillo, M. , Toledo-Pereyra, L. H. , Shapiro, E. , Guerra, E. , Prough, D. , Frantzis, P.: Protective effect of allopurinol, catalase, or SOD in the ischemic rat liver. Transplantation Proc. 22 (2): 490-491, 1990.
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• 14-26) Senga, S. , Onituka, A. , Hirose, H. , Yamamoto, K. , Niwa, K.: Protect, ive effect of liposomal encapsulated SOD on ischemically injured liver in the rat. Transplantation Proc. 22 (4): 2025-2026, 1990.

• 14-27) Kawamoto, S. , Inoue, M. , Tashiro, S. , Morino, Y. , Miyauchi, Y.: Role of free radicals in entero-hepatic dysfunction caused by portal circulatory disturbance-Effect of SOD derivative. Transplantation Proc. 21 (1): 1287-1289, 1989

• 14-28) Sakr, M. F. , Zetti, G. M. , Farghali, H. , Hassanein, T. H. , Gavaler, J. S. , Starzl, T E. , van Thiel, D. H.: Protective effect of FK506 against hepatic ischemia in rats Transplantation Proc. 23 (1): 340-341, 1991.

• 14-29) Ohhori, I. , Izumi, R. , Yabushita, K. , Watanabe, T. , Hashimoto, T. , Takamori, M. , Hirosawa, H. , Shimizu, K. , Konishi, K. , Miyazaki, I.: Prevention of liver damage by using free radical scavengers and changes in plasma PG levels during liver ischemia. Transplantation Proc. 121 (1): 1309-1311, 1989.

• 14-30) Cho, W. -H. , Kim, D. -G. , Murase, N. , Todo, S. , Starzl, T. E.: Comparison of superoxide dismutase, allopurinol, coenzyme Q10, and glutathione for the prevention of warm ischemic inj ury. Transplantation 50 (2): 353-355, 1990.

• 14-31) Sakr, M. F. , Zetti, G. M. , Hassanein, T. I. , Farghali, H. , Nalesnik, M. A. , Gavaler J. S. , Starzl, T. E. , van Thiel, D. H.: FK506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats. Hepatology 13: 947-951, 1991.
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• 14-32) Rao, P. N. , Walsh, T. R. , Makowka, L. , Rubin, R. S. , Weber, T. , Snyder, J. T., Starzl, T. E.: Purine nucleoside phosphorylase-A new marker for free oxygen radical injury to the endothelial cell. Hepatology 11: 193-198, 1990.

• 14-33) Rao, P. N. , Walsh, T. R. , Makowka, L. , Liu, T. , Demetris, A. J. , Rubin, R. S. , Snyder, J. T. , Mischinger, H. J. , Starzl, T. E.: Inhibition of free radical generation and improved survival by protection of the hepatic microvascular endothelium by targeted erythrocytes in orthotopic rat liver transplantation. Transplantation 49 (6): 1055-1059, 1990.
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• 14-34) Hasuoka, H. , Sakagami, K. , Orita, K.: Anew slow delivery type of SOD prevents warm ischemia damage in swine orthotopic liver transplantation. Transplantation Proc. 23 (1): 693-696, 1991.

• 14-35) Grankvist, K.: Gossypol-induced free radical toxicity to isolated islet cells. Int. J. Biochem. 21 (8): 853-856, 1989.
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• 14-36) Dabrowski, A. , Chwie6ko, M.: Oxygen radicals mediated depletion of pancreatic sulfhydryl compounds in rats with cerulein-induced acute pancreatitis. Digestion 47: 15-19, 1990.

• 14-37) Koiwai, T. , Oguchi, H. , Kawa, S. , Yanagisawa, Y. , Kobayashi, T. , Homma, T.: The role of oxygen free radicals in experimental acute pancreatitis in the rat. Int'l. J. of Pancreatology 5: 135-143, 1989.

第15章 消化器での活性酸素

P.278 掲載の参考文献

• 15-1) Tarnasky, P. R. , Livingston, E. H. , Jacobs, K. M. , Zimmerman, B. J. , Guth, P. H. , Garrick, T. R.: Role of oxyradicals in cold water immersion restraint-induced gastric mucosal injury in the rat. Digestive Diseases and Sciences 35 (2): 173-177, 1990.
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• 15-2) Ohara, T. , Matsuda, K. , Shibuya, D. , Eda, Y. , Yuki, T. , Asaki, S. , Toyota, T. , Kurokawa, T. , Sasaki, R.: Biochemical examination on the increased SOD-like plasma substance observed in a state of acute gastric mucosal lesions. Life Sci. 44: 1499-1504, 1989.

• 15-3) Pasou, O. , Dejica, D.: Oxygen free radicals and duodenal ulcer pain. Rev. . Rourn. Med. 25: 81-84, 1987

• 15-4) Teramura, S. , Murakami, M. , Saita, H. , Yoo, J. K. , Kusaka, S. , Matsuo, K. , Kita, T. , Miyake, T.: Effect of diethyldithiocarbamate on gastric and duodenal mucosal blood flow and vascular permeability in rats. Scand. J. Gastroenterol. 24 (suppl. 162): 108-111, 1989

• 15-5) Niida, H. , Okada, M. , Takeuchi, K. , Okabe, S.: Anew model of duodenal ulcers induced in rats by diethyldithiocarbamate, a SOD inhibitor. J. Gastroenterol. 24 (suppl. 162): 116-119, 1989

• 15-6) Oka, S. , Ogino, K. et al.: Role of active oxygen species in diethyldithiocarbamate-induced gastric ulcer in the rat. Experientia 46: 281-283, 1990.
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• 15-7) Hirota, M. , Inoue, M. , Ando, Y. , Morino, Y.: Inhibition of stress-induced gastric mucosal injury by a long acting SOD that circulates bound to albumin. Arch. Biochem. Biophys. 280 (2): 269-273, 1990.

• 15-8) Obayashi, H. , Koshi, S. , Miyauchi, Y. , Inoue, M.: Inhibition of post-hemorrhagic transfusion-induced gastric injury by a long-acting SOD derivative. Proc. of Soc. Expt'l. Biol. & Med. 196: 164-169, 1991.

• 15-9) Yoshikawa, T. , Naito, Y. et al.: Effect of zinc-carnosine chelate compound (Z-103) on burn-induced gastric mucosal injury in rats. J. Clin. Biochem. Nutr. 2: 107-113, 1989.

• 15-10) Nagy, L. , Mozsik, Gy. , Vincze, A. , Suto, G. Hunyady, B. , Rinfel, J. , Past, T. , Javor, T.: Effects of a novel Hungarian antacid containing Al and Mg (Tisacid) on mucosal prostaglandin generation and oxygen free radicals in normal rats. Drugs. Expt'l. Res. 16 (4): 197-203, 1990.

• 15-11) Uchida, K. , Kawakishi, S.: Cimetidine anti-ulcer drug as a powerful hydroxyl radical scavenger. Agr. Biol. Chem. 54 (9): 2485-2487, 1990.

• 15-12) Salim, A. S.: Removing oxygen-derived free radicals stimulates healing of ethanol-induced erosive gastritis in the rat. Digestion 47: 24-28, 1990.
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• 15-13) Robert, B. C. , Kennedy, T. P. , Piantadosi, C. A. , Whorton, A. R. , Canada, A. T. , Mercer, R. R. , Floyd, R. A. , Hoidal, J. R.: Piroxicam injures gastric mucosal epithelium by an oxidant mechanism. Clin Res. 38 (2): 534A, 1990.

• 15-14) Nissinen, E. , Linden, I. -B. , Pohto, P.: Glutathione sparing antioxidant properties of kitecapone. Pasadena Abst. 41, 1990.

• 15-15) Badylak, S. F. , Lantz, G. C. , Jeffries, M.: Prevention of reperfusion injury in surgically induced gastric dilatation-volvulus in dogs. Am. J. Vet. Res. 51 (2): 294-299, 1990.
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• 15-16) Karayalcin, S. S. , Sturbaum, C. W. , Wachsman, J. T. , Cha, J. -H. , Powell, D. W.: Hydrogen peroxide stimulates rat colonic prostaglandin production and alters electrolyte transport. J. Clin. Invest. 86: 60-68, 1990.
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• 15-17) Grisham, M B. , MacDermott, R. P. , Deitch, E. A.: Oxidant defense mechanisms in the human colon. Inflammation 14 (6): 669-680, 1990.
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• 15-18) Van der Vliet, A. , Tuinstra, T. J. R. , . Bast, A.: Modulation of oxidant stress in the gastro-intestinal tract and effect on rat intestinal motility. Biochem. Pharmacol. 38 (17): 2807-2818, 1989.

• 15-19) Kubes, P. , Suzuki, M. , Granger, D. N.: Modulation of PAF-induced leukocyte adherence and increased micro-vascular permeability. Am. J. Physiol 259: G859-864, 1990.

• 15-20) Murthy, S. N. S. , Cooney, C. G. , Clearfield, H. R.: Hydrogen peroxide-induced alterations in prostaglandin secretion in the rat colon in vitro. Inflammation 14 (6): 645-661, 1990.

• 15-21) Couinaud, C. , Goddio, A. S. , Elkoubi, P.: La superoxyde dismutase dans les phenomenes ischemiques chez l'homme. Chirurgie. 113: 897-901, 1987.

• 15-22) Emerit, J. , Pelletier, S. , Tosoni-Verlignue, D. , Mollet, M.: Phase II trial of copperzinc superoxide dismutase in treatment of Crohn's disease. Free Rad. Biol. & Med. 7: 145-149, 1989.

• 15-23) Fretland, D. J. , Widomski, D. L. et al.: Superoxide dismutase protects against acetic acid-induced colitis in mice. Pasadena Abst. 15. 14, 1990.

• 15-24) Suzuki, M. , Granger, D. N. et al.: Superoxide mediators reperfusion-induced leukocyte-endothelial cell interactions. Am. J. Physiol. 257: H1740-1745, 1989.
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• 15-25) Otamiri, T. , Tagesson, C.: Role of phospholipase A2 and oxygenated free radicals in mucosal damage after small intestinal ischemia and reperfusion. The Am. J. of Surgery 157: 562-566, 1989.

• 15-26) Wang, J. , Chen, H. , Wang, T. , Diao, Y. , Tian, K.: Oxygen-derived free radicals induced cellular injury in superior mesenteric artery occlusion shock. Circulatory Shock 32: 31-41, 1990.

• 15-27) Ozasa, T. , Kubota, S. , Kimura, M. , Hamaguchi, M. , Ohwada, S. , Watanabe, H.: Effect of SOD treetment on ischemia reperfusion injury in total small bowel. Pasadena Abst. 16. 21, 1990.

• 15-28) Brady III, C. E. , Cooley, B. J. , Davis, J. C.: Healing of severe perineal and cutaneous Crohn's disease with hyperbaric oxygen. Gastroenterology 97: 756-760, 1989.

第16章 腎臓での活性酸素

P.291 掲載の参考文献

• 16-1) S. Kestenbaum, R. , Adler, A. J. , Berlyne, G. M. , Caruso, C.: Effect of aluminium on superoxide dismutase. Clin. Sci. 77: 463-466, 1989.

• 16-2) Strand, W. R. , Sesterhenn, I. , Rushton, H. G.: Role of SOD in the pathogenesis of pyelonephritis-lmmunological localization of SOD in human renal tissues. J. of Urology 142: 616-618, 1989.

• 16-3) 竹村克己, 青柳一正, 永瀬宗重, 坂本まさ子, 石川敏子, 成田光陽:高圧酸素療法にお ける活性酸素マーカ-methylguanidine の動態. 日腎誌 32 (11):1195-1201, 1990.

• 16-4) Trznadel, K. , Luciak, M. , Pawlicki, L. , Kedziora, J. , Blaszczyk, J. , Buczyfiski, A.: Superoxide anion generation and lipid peroxidation processes during hemodialysis with reused cuprophan dialyzers. Free Rad. Biol. & Med. 8: 429-432, 1990.
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• 16-5) Asayama, K. , Shiki, Y. , Ito, H. , Hasegawa, O. , Miyao, A. , Hayashibe, H. , Dobashi, K. , Kato, K.: Antioxidant enzymes and lipoperoxide in blood in uremic children and adolescents. Free Rad. Biol. & Med. 9: 105-109, 1990.
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• 16-6) Cupisti, A. , Carulli, G. , Polidori, R. , Guidi, A. , Barsotti, G.: Superoxide anion production and dietary treatment in chronic renal failure. Nephron 57: 119-120, 1991.
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• 16-7) Yokozawa, T. , LiMo, Z. , Oura, H.: Comparison of toxic effects of methylguanidine, guanidinosuccinic acid and creatinine in rats with adenine-induced chronic renal failure. Nephron 51: 388-392, 1989.

• 16-8) Guidet, B. , Shah, S. V.: Enhanced in vivo H202 generation by rat kidney in glycerol-induced renal failure. Am. J. Physiol. 257: F440-445, 1989.

• 16-9) 服部新三郎, 辛嶋眞如, 古瀬昭夫, 松田一郎:ラット血清病腎炎におけるSODの効果. 日腎誌 32 (9):967-972, 1990.

• 16-10) Nath, K. A. , Croatt, A. J. , Hostetter, T. H.: Oxygen consumption and oxidant stress in surviving nephrons. Am. J. Physiol. 258: F1354-1362, 1990.
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• 16-11) Couinaud, C. , Desfemmes, F. , Elkoub, P.: La superoxydismutase en chirurgie generale. Chirurgie. 112: 148-154, 1986.

• 16-12) Jendryczko, A. , Drozdz, M.: Effect of superoxide dismutase on glomerular nephritis in rats with hydralazine-induced collagen-like syndrome. Rev. roum. Biochim. 26 (1): 41-46, 1989.

• 16-13) Vicens, A. , Lopez-Boado, M. A. , Alcaraz, A. , Saenz, A. , Piera, C, Hotter, G. , Ramos, E. , Klaustermeier, J. , Targarona, E. M. , Fernandez-Cruz, L.:Beneficial effect of SOD on erythrocyte trapping and 6-keto-PGF1α TXB2 ratio after ischemia-reperfusion in kidney transplantation. Transplantation Proc. 22(5):2221-2223, 1990.

• 16-14) Schneeberger, H. , Schleibner, S. , Schilling, M. , Illner, W. D. , Abendroth, D. , Hancke, E. , Jtinicke, U.: Prevention of acute renal failure after kidney transplantation by treatment with r-h-SOD. Transplantation Proc. 22 (5): 2224-2225, 1990.

• 16-15) Azou, B. L. , Cambar, J.: Protective effect of verapamil in cyclosporin-incubated isolated rat glomeruli. Toxicol. Letts. 53: 247-250, 1990.

• 16-16) 佐中 孜:腎とフリーラジカル. 最新医学 45(9):1784-1793, 1990.
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• 16-17) 小俣正子:実験的免疫複合体腎炎の発症ならびに進展過程における活性酸素の関与. 日腎誌 32(9):949-958, 1990.

• 16-18) Zager, R. A. , Gmur, D. J.: Effect of xanthine oxidase inhibition on ischemic acute renal failure in the rat. Am. J. Physiol. 257: F953-958, 1989.
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• 16-19) Thornton, M. A. , Zager, R. A.: Brief intermittent reperfusion during renal ischemia. J. Lab. Clin. Med. 115: 564-571, 1990.
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• 16-20) Healing, G. , Gower, J. , Fuller, B. , Green, C.: Intracellular iron redistribution-An important determinant of reperfusion damage to rabbit kidneys. Biochem. Pharmacol. 39 (7): 1239-1245, 1990.
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• 16-21) Scholz, H. , Schurek, H. -J. , Eckardt, K-U. , Bauer, C.: Role of erythropoietin in adaptation to hypoxia. Experientia 46: 1197-1201, 1990.
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• 16-22) Ratcliffe, P. J. , Jones, R. W. , Phillips, R. E. , Nicholls, L. G. , Bell, J. I.: Oxygendependent modulation of erythropoietin mRNA level in isolated rat kidneys studied by RNase protection. J. Exp. Med. 172: 657-660, 1990.
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• 16-23) Paller, M. S. , Hoidal, J. R. , Ferris, T. F.: Oxygen free radicals in ischemic acute renal failure in the rat. J. Clin. Invest. 74: 1156-1164, 1984.

• 16-24) Schneeberger, H. , Illner, W. D. , Abendroth, D. , Bulkley, G. , Rutili, F. , Williams, M. , Thiel, M. , Land, W.: First clinical experiences with SOD in kidney transplantation-Results of a double-blind randomized study. Transplantation Proc. 21 (1): 1245-1246, 1989.

• 16-25) Kaufman. Jr. R. P. , Klausner, J. M. , Anner, H. , Feingold, H. Kobzik, L. , Valeri, C. R. , Shepro, D. , Hechtman, H. B.: Inhibition of thromboxane synthesis by free radical scavengers. J. of Trauma. 28 (4): 458-464, 1988.

• 16-26) Bird, J. E. , Evan, A. P. , Peterson, O. W. , Blantz, R. C.: Early events in ischemic renal failure in the rat. Kidney International 35: 1282-1289, 1989.
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• 16-27) Bia, M. J. , Tyler, K.: Evidence that calcium channel blokcade prevents cyclosporin-induced exacerbation of renal ischemic injury. Transplantation 51 (2): 293-295, 1991.
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• 16-28) Shimizu, T. , Kawabata, T. , Nakamura, M: Protective effect of a novel calcium blocker, S-312-d, on ischemic acute renal failure in rat. J. of Pharmacol. and Experimental Therapeutics 255 (2): 484-490, 1990.

第17章 脳・神経系と活性酸素

P.312 掲載の参考文献

• 17-1) Del Maestro, R. , McDonald, W.: Distribution of SOD, glutathione peroxidase and catalase in developing rat brain. Mechanisms of Ageing and Development 41: 29-38, 1987.

• 17-2) Mariucci, G. , Ambrosini, M. V. , Colarieti, L. , Brushelli, G.: Differential changes in Cu, Zn and Mn SOD activity in developing rat brain and liver. Experientia 46: 753-755, 1990.

• 17-3) Evans, P. H. , Klinowski, J. , Yano, E. , Urano, N.: Alzheimer's disease, a pathogenic role for aluminosilicate-induced phagocytic free radicals. Free Rad. Res. Comms. 6 (5): 317-321, 1989.

• 17-4) Cadet, J. L. , Przedborski, S. , Kostic, V. , Jackson-Lewis, V. , Carlson, E. , Epstein, C. J.: Quantitative autoradiographic distribution of 3H-mazindol-labeled dopamine uptake sites in the brains of SOD transgenic mice. Brain Res. Bulletin 25: 187-192, 1990.

• 17-5) Schickler, M. , Knobler, H. , Avraham, K B. , Elroy-Stein, O. , Groner, Y.: Diminished serotonin uptake in platelets of transgenic mice with increased Cu, Zn-SOD activity. EMBO J. 8 (6): 1385-1392, 1989.

• 17-6) Ceballos-Picot, I. , Nicole, A. , Briand, B. , Grimber, G. , Javoy-Agid, F. , Lafon, M. , Sinet, P. M.: Neuronal-specific expression of Cu, Zn-SOD in transgenic mice. Pasadena Abst. 14. 12, 1990.

• 17-7) Somerville, M. J. , Percy, M. E. , Bergeron, C. , Yoong, L. K. K. , Grima, E. A. , McLachlan, D. R. C Localization and quantitation of 68kDa neurofilament and SOD-1 mRNA in Alzheimer brains. Mol. Brain Res. 9: 1-8, 1991.

• 17-8) Saggu, H. , Cooksey, J. , Dexter, D. , Wells, F. R. , Lees, A. , Jenner, P. , Marsden, C. D.: Aselective increase in particulate SOD activity in Parkinsonian substantia nigra. J. of Neurochem. 53: 692-697, 1987.

• 17-8a) Kurobe, N. , Inagaki, T. , Kato, K.: Sensitive enzyme immunoassay for human Mn-SOD. Clinica Chimica Acta 192: 171-180, 1990.

• 17-9) Sugita, T. , Endoh, S. , Iwata, I. , Kamiyama, K. , Ohtuji, T. , Takaku, A.: Pathological mechanism of experimental cerebral vasospasm induced by oxyhemoglobin. J. of Cerebral Blood Flow and Metabolism 7 (supp1. 1): S661, 1987.

• 17-10) Michelson, A. M. , Jadot, G. , Puget, K.: Treatment of brain trauma with liposomal SOD. Free Rad. Res. Comms. 4 (4): 209-224, 1988.

• 17-11) Domanska-Janik, K. , Bourre, J. M.: Effect of lipid peroxidation on Na+, K+-ATPase, 5'-nucleotidase and CNPase in mouse brain myelin. Biochim. Biophys. Acta 1034: 200-206, 1990.
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• 17-12) Deutschman, C. S. , Kirsch, J. R. , Breslow, M. J. , Miller, C. F. , Traystman, R. J.: Failure of endotoxic shock to elicit superoxide anion production in pig brain. Circulatory Shock 31: 149-158, 1990.
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• 17-13) Akai, F. , Maeda, M. , Suzuki, K. , Inagaki, S. , Takagi, H. , Taniguchi, N.: Immunocytochemical localization of Mn-SOD in the hippocampus of the rat. Neurosci. Letts. 115: 19-23, 1990.

• 17-14) Pourcyrous, M. , Leffler, C. W. , Mirro, R. , Busija, D. W.: Brain superoxide anion production during asphyxia and reventilation in newborn pigs. Pediatric Res. 28 (6): 618-621, 1990.

• 17-15) Cheng, Y. , Bu, Q. , Oldfield, E F. , Cowan, D. L. , Sun, A. Y.: The biochemical mechanism of the excitotoxocity of kainic acid. Pasadena Abst. 11. 15, 1990.

• 17-16) Philbert, M. A. , Waters, D. K. , Lowndes, H. E.: Cellular distribution of glutathione in the nervous system. Pasadena Abst. 2. 45, 1990.

• 17-17) Allain, P. , Krari, N.: Diethyldithiocarbamate, copper and neurological disorders. Life Sci. 48: 291-299, 1991.
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• 17-18) Ikeda, Y. , Anderson, J. H. , Long, D. M.: Oxygen free radicals in the genesis of traumatic and peritumoral brain edema. Neurosurgery 24 (5): 679-685, 1989.
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• 17-19) Ikeda, Y. , Ikeda, K. , Long, D. M.: Comparative study of different iron-chelating agents in cold-induced brain edema. Neurosurgery 24 (6): 820-824, 1989.
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• 17-20) Zhang, X. -M. , Ellis, E. F.: SOD reduces permeability and edema induced by hypertension in rats. Am. J. Physiol. 259: H497-H503, 1990.
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• 17-21) 黒河内彰, 森 則夫, 熊代 永:てんかん発作重積状態に対するSODの抗てんかん作用. 医学のあゆみ 152(7):465-466, 1990.

• 17-22) 平松 緑:けいれんと活性酸素. 神経精神薬理 10(8):529-538, 1988.

• 17-23) Liu, J. , Edamatsu, R. , Kabuto, H. , Mori, A.: Antioxidant action of Guilingji in the brain of rats with FeCl3-induced epilepsy. Free Rad. Biol. & Med. 9: 451-454, 1990.
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• 17-24) Plotnikov, M. B. , Saratikov, A. S. , Plonikova, T. M. , Khazanov, V. A. , Panina, O. P. , Kobzeva, E. A. , Ivanova, I. A. , Bobkov, Y. G.: Antihypoxic and antioxidative properties of bemitil. Bull. Exp. Biol. Med. Engl. Trans. 107 (5): 671-674, 1989.

• 17-25) Uchida, S. , Ohta, H. , Niwa, M. , Mori, A. , Nonaka, G. , Nishioka, I. , Ozaki, M.: Prolongation of life span of stroke-prone spontaneously hypertensive rats (SHRSP) ingesting persimmon tannin. Chem. Pharm. Bull. 38 (4): 1049-1052, 1990.
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• 17-26) Carrillo, M. -C. , Kanai, S. , Nokubo, M. , Kitani, K.: (-) Deprenyl induces activities of both SOD and catalase but not of glutathione peroxidase in the striatum of young male rats. Life Sci. 48: 517-521, 1991.

• 17-27) Kontos, H. A.: Oxygen radicals in CNS damage. Chem. -Biol. Interactions 72: 229-255, 1989.
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• 17-28) Cino, M. , Del Maestro, R. F.: Generation of hydrogen peroxide by brain mitochondria-The effect of reoxygenation following postdecapitative ischemia. Arch. of Biochem. Biophys. 269 (2): 623-638, 1989.
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• 17-29) Vass, K. , Welch, W. J. , Nowak, Jr. T. S.: Localization of 70-kDa stress protein induction in gerbil brain after ischemia. Acta Neuropathol. 77: 128-135, 1988.

• 17-30) 安東由喜雄, 井上正康:脳血管障害と活性酸素毒性の臓器相関. 日本老年医学会雑誌 27(2):166-170, 1990.

• 17-31) Kramer, K. , Voss, H. -P. , Grimbergen, J. A. , Timmerman, H. , Bast, A.: The effect of ischemia and recirculation, hypoxia, and recovery on anti-oxidant factors and β-adrenoceptor density. Biochem. Biophys. Res. Commun. 149 (2): 568-575, 1987.

• 17-32) Nakano, S. , Kogure, K. , Fujikura, H.: Ischemia-induced slowly progressive neuronal damage in the rat brain. Neuroscience 38 (1): 115-124, 1990.
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• 17-33) Oliver, C. N. , Starke-Reed, P. E. , Stadtman, E. R. , Liu, G. J. , Carney, J. M. , Floyd, R. A.: Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. USA 87: 5144-5147, 1990.
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• 17-34) Michowiz, S. D. , Melamed, E. , Pikarsky, E. , Rappapart, Z.: Effect of ischemia induced by middle cerebral artery occlusion on SOD activity in rat brain. Stroke 21: 1613-1617, 1990.

• 17-35) Schettini, A. , Lippman, H. , Walsh, E. K.: Attenuation of decompressive hypoperfusion and cerebral edema by SOD. J. Neurosurg. 71: 578-587, 1989.

• 17-36) Giampietro, D. E. P. , Cherici, G. , Alesiani, M. , Carla, V. , Moroni, F.: Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. The J. of Neuroscience 10 (3): 1035-1041, 1990.

• 17-37) Inoue, M. , Takeda, Y. , Hashimoto, H. , Kosaka, F. , Sasaki, J.: Inhibition of postischemic reperfusion injury of dog brain by a site directed SOD derivative. Pasadena Abst. 16. 13, 1990.

• 17-38) Morgenstern, E. , Rastock, A. , Siegemund, Ch. , Gores, E. , Bartsch, R. , Wustman, Ch. , Fischer, H. -D.: Anti-hypoxic effects of AWD23-15 in mice and rats. Biomed. Biochim. Acta 48 (2/3): S247-250, 1989.

• 17-39) Ban, M. , Tonai, T. , Kohno, T. , Matsumoto, K. , Horie, T. , Yamamoto, S. , Moskowitz, M. A. , Levine, L.: Aflavonoid inhibitor of 5-lipoxygenase inhibits leukotriene production following ischemia in gerbil brain. Stroke 20: 248-252, 1989.

• 17-40) Martz, D. , Rayos, G. , Schielke, G. P. , Betz, A. L.: Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in rats. Stroke 20: 488-494, 1989.
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• 17-41) Halle, E. D. , Pazara, K. E. , Braughler, J. M. , Linseman, K. L. , Jacobsen, E. J.: Nonsteroidal Lazaroid U78517F in models of focal and global ischemia. Stroke 21 (suppl. III): 83-87, 1990.

• 17-42) Gilboe, D. D. , Kintner, D. , Fitzpatrik, J. H. , Emoto, S. , Esanu, A. , Braquet, P. G. , Bazan, N. G.: Recovery of postischemic brain metabolism and function following treatment with a free radical scavenger and platelet-activating factor agonists. J. of Neurochemistry 56: 311-319, 1991.

• 17-43) Acker, H. , Dufau, E. , Huber, J. , Sylvester, D.: Indication to an NADPH oxidase as apossible pO2 sensor in the rat carotid body. FEBS Letts. 256 (1/2): 75-78, 1989.

• 17-44) Segura-Aguilar, J. , Lind, C.: On the mechanism of the Mn3+-induced neurotoxicity of dopamine-Prevention of quinone-derived oxygen toxicity by DT diaphorase and SOD. Chem∴Biol. Interactions 72: 309-324, 1989.

• 17-45) Aizenman, E. , Hartnett, K. A. , Reynold, I. J.: Oxygen free radicals regulate NMDA receptor function via a redox modulatory site. Neuron 5: 841-846, 1990.

• 17-46) Eastman, C. L. , Guilarte, T. R.: The role of hydrogen peroxide in the in vitro cytotoxicity of 3-hydroxy kynureine. Neurochem. Res. 15 (11): 1101-1107, 1990.

• 17-47) Jackson, G. R. , Apffel, L. , Werrbach-Perez, K. , Perez-Polo, J. R.: Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury I. J. of Neurosci. Res. 25: 360-368, 1990.

• 17-48) Kassabova, T. , Staykova, M. , Balevska, P. , Atanassov, B. , Goranov, I.: Antioxidant capacity of spinal cord and erythrocytes of guinea pigs in case of experimental allergic encephalomyelitis and after disease suppression. Acta Neurol. Scand, 82: 116-120, 1990.
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• 17-49) Lund-Olesen, K.: Intrathecal Orgotein. Int. J. Clirl. Pharm. Res. 5 (1): 59-62, 1985.

• 17-50) Chan, P. H. , Chu, L. , Chen, S. F. , Carlson, E. J. , Epstein, C. J.: Reduced neurotoxicity in transgenic mice overexpressing human Cu, Zn-SOD. Stroke 21 (suppl. III): 80-82, 1990.

• 17-51) Colton, C. A. , Yao, J. , Gilbert, D. , Oster-Granite, M. -L.: Enhanced production of superoxide anion by microglia from trisomy 16 mice. Brain Res. 519: 236-242, 1990.
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• 17-52) Groner, Y. , Elroy-Stein, O. , Avraham, K. B. , Yarom, R. , Schickler, M. , Knobler, H. , Rotman, G.: Down syndrome clinical symptoms are manifested in transfected cells and transgenic mice overexpressing the human Cu, Zn-SOD. J. Physiol. (Paris) 84: 53-77, 1990.

第18章 筋肉・皮膚・骨と活性酸素

P.327 掲載の参考文献

• 18-1) Galaris, D. , Cadenas, E. , Hochstein, P.: Redox cycling of myoglobin and ascorbate A potelltial protective mechanism against oxidative reperfusion injury in muscle. Arch. of Biochem. Biophysics 273 (2): 497-504, 1989.

• 18-2) Sirsjo, S. , Soderkvist, P. , Gustafsson, U. , Lewis, D. H. , Nylander, G.: The relationship between blood flow, development of edema and leukocyte accumulation in post-ischemic rat skeletal muscle. Microcirculation Endothelium and Lymphatics 6 (1): 21-34, 1990.

• 18-3) Terrados, N. , Jansson, E. , Sylv?n, C. , Kaljser, L.: Is hypoxia a stimulus for synthesis of oxidative enzymes and myoglobin? . J. Appl. Physiol. 68 (6): 2369-2372, 1990.

• 18-4) Carden, D. L. , Smith, J. K. , Korthuis, R. J.: Neutrophil-mediated microvascular dysfunction in postischemic canine skeletal muscle Role of granulocyte adherence. Circulation Res. 66: 1436-1444, 1990.
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• 18-5) Lindsay, T. F. , Liauw, S. , Romaschin, A. D. , Walker, P. W.: The effect of ischemia/reperfusion on adenine nucleotide metabolism and xanthine oxidase production in skeletal muscle. J. Vasc. Surg. 12: 8-15, 1990.

• 18-6) Mars, M. , Gregory, M. A.: Ahistometric analysis of skeletal myofibers following 90min of tourniquet ischemia and reperfusion. J of Surgical Res. 50: 191-195, 1991.

• 18-7) Freisleben, H. -J. , Beyerdorf, F. , Seewalda, P. , Simon, J. , Zimmer, G.: Dihydrolipoic acid decreases postischemic reperfusion damage in rat hindlimbs. Pasadena Abst. 10. 16, 1990.

• 18-8) Laughlin, M. H. , Simpson, T. , Sexton, W. L. , Brown, O. R. , Smith, J. K. , Korthuis, R. J.: Skeletal muscle oxidative capacity, antioxidant enzymes, and exercise training. J. Appl. Physiol. 68 (6): 2337-2343, 1990.
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• 18-9) Okada, K.: Reversible changes of skeletal muscular capillaries after application of atourniquet. Microvascular Res. 39: 156-168, 1990.

• 18-10) Vedder, N. B. , Winn, R. K. , Rice, C. L. , Chi, E. Y. , Arfors, K. -E. , Harlan, J. M.: Inhibition of leukocyte adherence by anti-DC18 monoclonal antibody attenuates reperfusion injury in the rabbit ear. Proc. Natl. Acad. Sci. USA 87: 2643-2646, 1990.

• 18-11) Ricci, M. A. , Graham, A. M. , Corbisiero, R. , Baffour, R. , Mohamed, F. , Symes, J. F.: Are free radical scavenger beneficial in the treatment of compartment syndrome after acute arterial ischemia? J. Vasc. Surg. 9: 244-250, 1989.
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• 18-12) Redl, H. , Schlag, G. , Gasser, H. , Dinges, H. -P.: hs SOD does not prevent bacterial tranlocation (BT) in a baboon polytrauna model Pasadena Abst. 16. 23, 1990.

• 18-13) Manson, P. N. , Jesudass, R. , Marzella, L. , Bulkley, G. B. , Im, M J. , Narayan, K. K.: Evidence for an early free radical-mediated reperfusion injury in frostbite. Free Rad. Biol. & Med. 10: 7-11, 1991.
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• 18-14) Novelli, G. P. , Adembri, C. , Brunelleschi, S. , Livi, P. , Rossi, R. , Pratesi, C.: Oxygen-radicals production during ischemia-reperfusion of the lower Iimbs in man-lnhibitory effects of L-carnitine. Current Therapeutic Res. 48 (5): 903-911, 1990.

• 18-15) ucks, J. , Huflejt, M. E. , Rothfuss, L. M. , Wilson, D. S. , Carcamo, G. , Packer, L.: Impairment of enzymic and nonenzymic antioxidants in skin by UVB irradiation. J. Invest. Dermatol. 93: 769-773, 1989.

• 18-16) Pence, B. C. , Naylor, M. F.: Effects of single-dose UV radiation on skin SOD, catalase and XOD in hairless mice. J. Invest. Dermatol 95: 213-216, 1990.

• 18-17) Ranadive, N. S. , Menon, I. A. , Shirwadkar, S. , Persad, S. D.: Quantitation of cutaneous inflammation induced by reactive speciens generated by UV-visible irradiation of rose bengal. Inflammation 13 (5): 483-494, 1989.

• 18-18) Murrell, G. A. C. , Francis, M. J. O. , Bromley, L.: Modulation of fibroblast proliferation by oxygen free radicals. Pasadena Abst. 11. 28, 1990.

• 18-19) Zizic, T. M. , Marcoux, C. , Hungerford, D. S. , Stevens, M. B.: The early diagnosis of ischemic necrosis of bone. Arthritis and Rheumatism 29 (10): 1177-1186, 1986.
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• 18-20) Nevo, Z. , Beit-Or, A. , Eilam, Y.: Slowing down aging of cultured embryonal chick chondrocytes by maintenance under lowered oxygen tension. Mechanism of Ageing and Development 45: 157-165, 1988.

• 18-21) Niwa, Y.: Lipid peroxide and SOD induction in skin inflammatory diseases, and treatment with SOD preparations. Dermatologica 179 (Suppl. 1): 101-106, 1989.

• 18-22) 梅村芳樹, 杉浦 衛・他:ラット急性刺激皮膚炎の皮膚過酸化脂質とSOD活性の変動とSOD外用による過酸化脂質の抑制. 皮膚 31(6):778-784, 1989.

• 18-23) Hamanaka, H. , Miyachi, Y. , Imamura, S.: Photoprotective effect of topically applied SOD on sunburn reaction in comparison with sunscreen. The J. of Dermatology 17: 595-598, 1990.

• 18-24) Yoon, J. O. , Im, M. J. , Manson, P. N. , Bulkley, G. B. , Iloopes, J. E.: The role of metal ions in ischemia/reperfusion injury in skin flaps. J of Surgical Res. 46: 163-165, 1989.

• 18-25) Fucks, J. , Milbradt, R. , Zimmer, G.: Dihydrolipoate inhibits reactive oxygenspecies mediated skin inflammation. Pasadena Abst. 20. 16, 1990.

第19章 生殖機能と活性酸素

P.339 掲載の参考文献

• 19-1) 野田洋一, 松本 央, 森 崇英: SOD によるマウス2-cell block の解除. 日本産科婦人科学会雑誌 41(6):751-752, 1989.

• 19-2) 馬岡 陽, 野田洋一, 松本 央, 森 崇英:マウス前核期胚培養における酸素毒性の影響. 日本不妊学会雑誌 35(2):45-52, 1990.

• 19-3) 松本 央, 野田洋一, 馬岡 陽, 森 崇英: SOD によるマウス2-cell block の解除. 日本不妊学会雑誌 35(2):53-59, 1990.

• 19-4) Noda, Y. , Matsumoto, H. , Umaoka, Y. , Tatsumi, K. , Kishi, J. , Mori, T.: Involvement of superoxide radicals in the mouse two-cell block. Mol. Reproduction and Development 28: 356-360, 1991.
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• 19-5) Downs, S. M. , Dow, M. P. D.: Hypoxanthine-mediated two-cell block in mouse embryo Dependence on glucose and effect of hypoxanthine phosphoribosyl-transferase inhibitors. Biol. of Reproduction 44: 1025-1039, 1991.

• 19-6) Eriksson, U. J. , Borg, L. A. H.: Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro. Diabetologia 34: 325-331, 1991.

• 19-7) Narimoto, K. , Noda, Y. , Shiotani, M. , Tokura, T. , Goto, Y: , Takakura, K. , Mori, T. , Fujimoto, K. , Ogawa, K.: Immunohistochemical assessment of superoxide dismutase expression in the human endometrium throughout the menstrual cycle. Acta Histochem. Cytochem. 23 (4): 487-498, 1990.

• 19-8) Takehara, Y. , Yoshioka, T. , Sasaki, J.: Changes in the levels of lipoperoxide and antioxidant factors in human placenta during gestation. Acta Med. Okayama 44 (2): 103-111, 1990.
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• 19-9) Laloraya, M. , Kumar, G. P. , Nivsarkar, M. , Laloraya, M. M.: Localization of SOD in the ovary and uterus of mice during pregnancy with special reference to steroidogenesis and implantation. Acta Histochem. Cytochem. 23 (3): 271-279, 1990.

• 19-10) Masumoto, N. , Tasaka, K. , Miyake, A. , Tanizawa, O.: Superoxide anion increases intracellular free calcium in human myometrical cells. J. Biol. Chem. 265 (36): 22533-22536, 1990.

• 19-11) 中谷剛彬, 林 好寛, 八神喜昭, 鈴木敬一郎, 谷口直之:羊絨毛膜炎による切迫早産および preterm PROM 妊婦における血中 Mn-SOD の動態. 第12回日本炎症学会抄録, 1991, p103.

• 19-12) Miyazaki, T. , Sueoka, K. , Dharmarajan, A. M. , Atlas, S. J. , Bulkley, G. B. , Wallach, E. E.: Effect of inhibition of oxygen free radical on ovulation and progesterone production by the in vitro perfused rabbit ovary. J. Reprod. Fert. 91: 207-212, 1991.

• 19-13) 須戸龍男:排卵過程における過酸化脂質およびfree radical scavengers活性の変動と scavenger enzymesによる排卵阻害効果. 日本不妊学会雑誌 35(2):349-355, 1990.

• 19-14) Srivastava, R. S. , Murthy, R. C. , Chandra, S. V.: Effect of manganese on some bioantioxidants in various organs of protein-defficient rats. Biochem. Int'l. 18 (5): 903-912, 1989.

• 19-15) Sinha, S. , Pradeep Kumar, G. , Laloraya, M. , Warikoo, D.: Over-expression of SOD and lack of surface-thiols in spermatozoa-lnherent defects in oligosperma. Biochem. Biophys. Res. Commun. 174 (2): 510-517, 1991.

• 19-16) Ciavatti, M. , Renaud, S.: Oxidative status and oral contraceptive-Its relevance to platelet abnormalities and cardiovascular risk. Free Rad. Biol. & Med. 10: 325-338, 1991.
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• 19-17) Beconi, M. T. , Affranchino, M. A. , Schang, L. M. , Beorlegui, N. B.: Influence of antioxidants on SOD activity in bovine sperm. Biochem. Int'l. 23 (3): 545-553, 1991.

• 19-18) Foerder, C. A. , Klebanoff, S. J. , Shapiro, B. M.: Hydrogen peroxide production, chemiluminescence, and the respiratory burst of fertilization. Proc. Natl. Acad. Sci. USA 75 (7): 3183-3187, 1978.
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• 19-19) Heinecke, J. W. , Shapiro, B. M.: Superoxide peroxidase activity of ovoperoxidase, the cross-linking enzyme of fertilization. J. Biol. Chem. 265 (16): 9241-9246, 1990.
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第20章 眼・口腔・耳鼻と活性酸素

P.351 掲載の参考文献

• 20-1) Bhuyan, K. C. , Master, R. W. P. , Bhuyan, D. K.: Oxyradical-induced polymerization of aminophospholipids in cataract. Superoxide and Superoxide Dismutase in Chemistry. (ed. Rotilio, G. Elsevir Sci. Publishers B. V. ), 1986, p 651-656.

• 20-2) Ansari, N. H. , Srivastava, S. K.: Allopurinol promotes and butylated hydroxy toluene prevents sugar-induced cataractogenesis. Biochem. Biophys. Res. Commun. 168 (3): 939-943, 1990.
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• 20-3) Bando, M. , Obazawa, H.: Activities of ascorbate free radical reductase and H202-dependent NADH oxidation in senile cataractous human lenses. Exp. Eye Res. 50: 779-784, 1990.

• 20-4) Woollard, A. C. S. , Wolff, S. P. , Bascal, Z. A.: Antioxidant characteristics of some potential anticataract agents. Free Rad. Biol. & Med. 9: 299-305, 1990.

• 20-5) Rao, N. A. , Calandra, A. J. , Sevanian, A. , Bowe, B. , Delmage, J. M. , Marak, Jr. G. E.: Modulation of lens-induced uveitis by SOD. Ophthalmic Res. 18: 41-46, 1986.

• 20-6) Ando, E. , Ando, Y. , Inoue, M. , Morino, Y. , Kamata, R. , Okamura, R.: Inhibition of corneal inflammation by an acylated SOD derivative. Investigative Ophthalmology & Visual Sci. 31 (10): 1963-1967, 1990.

• 20-7) Nakamori, K. , Koyama, I. , Nakamura, T. , Yoshida, T. , Umeda, M. , Inoue, K.: Effectiveness of taurine in protecting biomembrane against oxidant. Chem. Pharm. Bull 38 (11): 3116-3119, 1990.
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• 20-8) Yeh, L. -A. , Ashton, M. A.: The increase in Iipid peroxidation, in diabetic rat lens can be reversed by oral sorbinil. Metabolism 39 (6): 619-622, 1990.

• 20-9) Babizhayev, M. A.: Antioxidant activity of L-carnosine, a natural histidinecontaining dipeptide in crystalline lerls. Biochim. Biophys. Acta 1004: 363-371, 1989.
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• 20-10) Del Corso, A. , Baracchi, D. , Giannessi, M. , Tozzi, M. G. , Camici, M. , Mura, U.: Change in stereospecificity of bovine lens aldose reductase modified by oxidative stress. J. Biol. Chem. 264 (30): 17653-17655, 1989.

• 20-11) Lux-Neuwirth, O. , Millar, T. J.: Lipid soluble antioxidant preserve rabbit corneal cell function. Current Eye Res. 9 (2): 103-109, 1990.

• 20-12) Doly, M. , Braquet, M. T.: Oxygenated free radicals and electrophysiology of isolated rat retina-Protection by a Ginkgo biloba extract (EGB 761) . Pasadena Abst. 2. 14, 1990.

• 20-13) Whyte, G. J. , Seymour, G. J. , Cheung, K. , Robinson, M. F.: Chemiluminescence of peripheral polymorphonuclear leukocytes from adult periodontitis patients. J. Clin. Periodontol. 16: 69-74, 1989.
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• 20-14) 三崎広樹, 鈴木 誠, 吉江弘正, 原 耕二:ラットの歯周病原性細菌による炎症および歯肉の創傷に対する SOD 投与の効果. 日歯周誌 32(1):93-110, 1990.

• 20-15) Shapira, L. , Borinski, R. , Sela, M. N. , Soskolne, A.: Superoxide formation and chemiluminescence of peripheral polymorphonuclear leukocytes in rapidly progressive periodontitis patients. J. of Clin. Periodontology 18 (1):44-48, 1991.
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• 20-16) Terao, J. , Nagao, A.: Antioxidative effect of human saliva on lipid peroxidation. Agric. Biol. Chem. 55 (3): 869-872, 1991.

• 20-17) Watanabe, K. , Harada, H.: Beta-adrenoceptor control of peroxidase synthesis in nasal gIands. Ann. Otol. Rhinol. Laryngol. 99: 581-585, 1990.
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• 20-18) Peden, D. B. , Hohman, R. , Brown, M. E. , Mason, R. T. , Berkebile, C. , Fales, H. M. , Kaliner, M. A.: Uric acid is a major antioxidant in human nasal airway secretions. Proc. Natl. Acad. Sci. USA 87: 7638-7642, 1990.

• 20-19) Umemura, K. , Kohno, Y. , Matsuno, H. , Uematsu, T. , Nakashima, M.: A new model for photochemically induced thrombosis in the inner ear microcirculation and the use of hearing loss as an measure for microcirculatory disorders. Eur. Arch. of Oto-Rhino-Laryngology 248: 105-108, 1990.

• 20-20) Kohno, Y. , Nakashima, M. et al.: A new model of hearing loss due to the photo hemically induced thrombosis in the inner ear microcirculation. Eur. J. Pharmacol. 183 (Congres Abst. ): 1839, 1990.

第21章 赤血球と血管での活性酸素

P.363 掲載の参考文献

• 21-1) De la Torre, M. R. , Casado, A. , Lopez-Fernandez, M. E: Superoxide dismutase activity in the Spanish population. Experientia 46: 854-856, 1990.
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• 21-2) Vanella, A. , Scalia, R. , Terminella, C. , Gambera, G. , Castoria, C. , Sorrenti, V. , Campisi, A. , Bianchi, A.: Antioxidant enzymatic systems in human erythrocytes from subjects with chronic cerebrovascular disease. Pharmacological Res. 22 (3): 271-276, 1990.

• 21-3) Munday, R.: Toxicity of thiols and disulphines-involvement of free-radical species. Free Rad. Biol. & Med. 7: 659-673, 1989.
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• 21-4) Lachant, N. A. , Zerez, C. R.: Inhibitory effect of mannose on erythrocyte defense against oxidants. Biochim. Biophys. Acta 964: 96-104, 1988.
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• 21-5) Levine, S. N. , Berkowitz, L. R. , Orringer, E P.: Cetiedil inhibition of calmodulinstimulated enzyme activity. Biochem. Pharmacol. 33 (4): 581-584, 1984.
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• 21-6) Salvemini, D. , de Nucci, G. , Vane, J. R.: SOD cooperates with prostacyclin to inhibit platelet aggregation. Thrombosis and Haemostasis 65 (4): 421-424, 1991.
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• 21-7) Vercellotti, G. M. , Severson, S. P. , Duane, P. , Moldow, C. F.: Hydrogen peroxide alters signal transduction in human endothelial cells. J. Lab. Clin. Med. 117: 15-24, 1991.
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• 21-8) Ager, A. , Gordon, J. L.: Differential effects of hydrogen peroxide on indices of endothelial cell function. J. Exp. Med. 159: 592-603, 1984.
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• 21-9) Lawson, D. L. , Mehta, J. L. , Nichols W. W. , Mehta, P. , Donnelly, W. H.: Superox. ide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings. J. Lab. Clin. Med. 115: 541-548, 1990.

• 21-10) Rhoades, R. A. , Packer, C. S. , Roepke, D. A. , Jin, N. , Meiss, R. A.: Reactive oxygen species alter contractile properties of pulmonary arterial smooth muscle. Can. J. Physiol. Pharmacol. 68: 1581-1589, 1990.
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• 21-11) Beckman, J. S. , Minqr Jr. R. L. , White, C. W. , Repine, J. E. , Rosen, G. M. , Freeman, B. A.: SOD and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance. J. Biol. Chem. 263 (14): 6884-6892, 1988.

• 21-12) Markey, B. A. , Phan, S. H. , Varani, J. , Ryan, U. S. , Ward, P. A.: Inhibition of cytotoxicity by intracellular SOD supplementation. Free Rad. Biol. & Med. 9: 307-314, 1990.
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• 21-13) Michiels, C. , Toussaint, O. , Remacle, J.: Comparative study of oxygen toxicity in human fibroblasts and endothelial cells. J. of Cellul. Physiol. 144: 295-302, 1990.

• 21-14) Shaffer, J B. , Treanor, C. P. , Del Vecchio, P. J.: Expression of bovine and mouse endothelial cell antioxidant enzymes following TNF-α exposure. Free Rad. Biol. & Med. 8: 497-502, 1990.

• 21-15) Shatos, M. A. , Doherty, J. M. , Stump, D. C. , Thompson, E. A.: Oxygen radicals generated during anoxia followed by reoxygenation reduce the synthesis of tissuetype plasminogen activator and plasminogen activator inhibitor-1 in human endothelial cell culture. J. of Biol. Chem. 265 (33): 20443-20448, 1990.
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• 21-16) Rakugi, H. , Tabuchi, Y. , Nakamura, M. , Nagano, M.: Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia. Biochem. Biophys. Res. Commun. 169 (3): 973-977, 1990.

• 21-17) Bhat, G. B. , Block, E. R.: Hypoxia directly increases serotonin transport by porcine pulmonary artery endothelial cell plasma membrane vesicles. Am. J. Respir. Cell Mol Biol. 3: 363-367, 1990.
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• 21-18) Ratych, R. E. , Chuknyiska, R. S. , Bulkley, G. B.: The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells. Surgery 102: 122-131, 1989.

第22章 動脈硬化と活性酸素

P.375 掲載の参考文献

• 22-1) Leake, D. S. , Rankin, S. M. , : The oxidative modification of low density lipoproteins by macrophage. Biochem. J. 270: 741-748, 1990.
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• 22-2) Rosenfeld, M. E. , Khoo, J. C. , Miller, E. , Parthasarathy, S. , Palinski, W. , Witztum, J. L.: Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts. J. Clin. Invest. 87: 90-99, 1991.
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• 22-3) Huber, L. A. , Scheffler, E. , Poal, T. , Ziegler, R. , Dresel, H. A.: 17-beta-estradiol inhibits LDL oxidation and cholesteryl ester formation in cultured macrophages. Free Rad. Res. Comms. 8 (3): 167-173, 1990.

• 22-3a) Azizova, O. A. , Panasenko, O. M. , Vol'nova, T. V. , Vladimirov, Y. A.: Free radical lipid oxidation affects cholesterol transfer between lipoproteins and erythrocytes. Free Rad. Biol. & Med. 7: 251-257, 1989.

• 22-4) Jialal, I. , Vega, G. L. , Grundy, S. M: Physiologic Ievels of ascorbate inhibit the oxidative modification of low density lipoprotein. Atherosclerosis 82: 185-191, 1990.

• 22-5) Camejo, G. , Hurt, E. , Rosengren, B. , Bondjers, G.: Interaction of low density lipoproteins (LDL) with arterial proteoglycans markedly increase its susceptibility to oxidation by copper and uptake by cells. Pasadena Abst. 7. 16, 1990.

• 22-6) Steinbrecher, U. P. , Zhang, H. , Lougheed, M.: Role of oxidatively modified LDL in atherosclerosis. Free Rad. Biol. & Med. 9: 155-168, 1990.
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• 22-7) 林 幸三, 堂上慎也, 平田康彦, 大谷博正, 中島浩一郎, 西尾栄助, 佐伯正弦, 久留島 仁, 梶山梧郎:ヒト単球細胞分化による LDL レセプターの代謝変化とスカベンジャー レセプターの出現. 医学のあゆみ 154 (2):141-142, 1990.

• 22-8) Kume, N. , Arai, H. , Kawai, C. , Kita, T.: Receptors for modified low-density lipoproteins on human endothelial cells-Different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein. Biochim. Biophys. Acta 1091: 63-67, 1991.
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• 22-9) Matsumoto, A. , Kodama, T. et al.: Human macrophage scavenger receptors-Primary structure expression, and localization in atherosclerotic lesions. Proc. Natl Acad. Sci. USA 87: 9133-9137, 1990.

• 22-10) Chander, R. , Kapoor, N. K.: High density lipoprotein is a scavenger of superoxide anions. Biochem. Pharmacol. 40 (7): 1663-1665, 1990.
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• 22-11) 土井健史, 児玉龍彦, 松本明世:動脈硬化とマクロファージスカベンジャーレセプター. ファルマシア 26 (11):1137-1142, 1990

• 22-12) Wilson, S. K.: Role of oxygen-derived free radicals in acute angiotensin II -induced hypertensive vascular disease in the rat. Circulation Res. 66:722-734, 1990.
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• 22-13) McNally, A. K. , Chisolm III, G. M. , Morel, D. W. , Cathcart, M. K.: Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependentpathway. J. of Immunol. 145 (1): 254-259, 1990.

• 22-14) Barnbart, R. L. , Busch, S. J. , Jackson, R. L.: Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro. J. Lipid Res. 30: 1703-1710, 1989.

• 22-15) Modi, K. S. , Morrissey, J. , Shah, S. , V. Schreiner, G. F. , Klahr, S.: Effects of probucol on renal function in rats with bilateral ureteral obstruction. Kidney Int'l. 38: 843-850, 1990.

• 22-16) Kalyanaraman, B. , Parthasarathy, S.: The synergistic interaction between the probucol phenoxyl radical, ev-tocopherol, ascorbic acid in LDL oxidation. Pasadena Abst. 7. 20, 1990.

• 22-17) Mao, S. J. T. , Yates, M. T. , Rechtim, A. E. , Jackson, R. L. , Van Sickle, W. A.: Anti-oxidant activity of probucol and its analogues in hypercholesterolemic Watanabe rabbits. J. Med. Chem. 34: 298-302, 1991.

• 22-18) Suda, N. , Morita, L. , Hibino, H. , Kuroda, T. , Murota, S.: Endothelial cells enriched with oleic acid are resistant to neutrophil-mediated free radicals. Pasadena Abst. 13. 20, 1990.

• 22-19) Wang, J. , Zhen, E. , Guo, Z. , Lu, Y.: Effect of hyperlipidemic serum on lipid peroxidation, synthesis of prostacyclin and thromboxane by cultured endothelial cells. Free Rad. Biol. & Med. 7: 243-249, 1989.

• 22-20) de Whalley, C. V. , Rankin, S. M. , Hoult, J. P. S. , Jessup, W.: Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophage. Biochem. Pharmacol. 39 (11): 1743-1750, 1990.

• 22-21) Bin, Q. H.: Nitric oxide-a revolution of free radicals theory of aging. Medical Hypotheses. 34: 60-61, 1991. 22-22) Janero, D. R.: Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Rad. Biol. & Med. 9: 515-540, 1990.

• 22-23) Muscari, C. , Caldarera, C. M. , Guarnieri, C.: Age-dependent production of mito chondrial hydrogen peroxide, lipid peroxides and fluorescent pigments in the rat heart. Basic Res. in Cardiology 85: 172-178, 1990.

• 22-24) Jain, S. K. , Ross, J. D. , Levy, G. J. , Duetl, J.: The effect of malonyldialdehyde on viscosity of normal and sickle red cells. Biochem. Med. and Metabolic Biol. 44: 37-41, 1990.

• 22-25) Duthie, G. G. , Robertson, J. D. , Maughhan, R. J. , Morrice, P. C.: Blood antioxidant status and erythrocyte lipid peroxidation following distance running. Arch. of Biochem. Biophys. 282 (1): 78-83, 1990.

• 22-26) McIntyre, T. M. , Stremler, K. E. , Stafforini, D. M. , Prescott, S. M.: Selective hydrolysis of oxydatively-fragmented phospholipids by the PAF acetylhydrolase. Pasadena Abst. 13. 15, 1990.

• 22-27) DeLange, R. J. , Glazer, A. N.: Bile acids-antioxidants or enhancers of peroxidation depending on lipid concentration. Arch. of Biochem. Biophys. 276 (1): 19-25, 1990.
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第23章 糖尿病・ホルモンと活性酸素

P.387 掲載の参考文献

• 23-1) Sakurai, T. , Tsuchiya, S.: Superoxide production from nonenzymatically glycated protein. FEBS Letts. 236: 406-410, 1988.

• 23-2) Mullarkey, C. J. , Edelstein, D. , Brownlee, M.: Free radical generation by early glycation products-A mechanism for accelerated atherogenesis in diabetes. Biochem. Biophys. Res. Commun. 173 (3): 932-939, 1990.
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• 23-3) Sumoski, W. , Baquerizo, H. , Rabinovitch, A.: Oxygen free radical scavegers protect rat islet cells from damage by cytokines. Diabetologia 32: 792-796, 1989.
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• 23-4) Yaguchi, Y. , Tomino, Y. , Watanabe, S. , Koide, H.: Detection of malondiadehyde levels and SOD activities in renal tissue of nonobese diabetic mice. Nephron 54: 368, 1990.

• 23-5) Jongkind, J. F. , Verkerk, A. , Baggen, R. G. A.: Glutathione metabolism of human vascular endothelial cells under peroxidative stress. Free Rad. Biol. & Med. 7: 507-512, 1989.
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• 23-6) Selvam, R. , Anuradha, C. V.: Effect of oral methionine on blood lipid peroxidation and antioxidants in alloxan-induced diabetic rats. J. Nutr. Biochem. 1: 653-658, 1990.
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• 23-7) Adamo, A. M. , Llesuy, S. F. , Pasquini, J. M. , Boveris, A.: Brain chemiluminescence and oxidative stress in hyperthyroid rats. Biochem. J. 263: 273-277, 1989.
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• 23-8) Nakamura, Y. , Ohtaki, S. , Makino, R. , Tanaka, T. , Ishimura, Y.: Superoxide anion is the initial product in the hydrogen peroxide formation catalyzed by NADPH oxidase in porcine thyroid plasma membrane. J. Biol. Chem. 264 (9): 4759-4761, 1989.
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• 23-9) Faure, M. , Lissi, E. A. , Videla, L. A.: Evaluation of the antioxidant properties of thyroid hormones and propylthiouracil in the brain--homogenate autoxidation system and in the free radical-mediated oxidation of erythrocyte membranes. Chem. -Biol. Interactions 77: 173-185, 1991.
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• 23-10) Eriksson, C. -G. , Eneroth, P.: Peroxidation in position C-60f progesterone-3-ethanolimine is increased by the presence of enzymes generating oxygen radicals. Steroids 55: 366-372, 1990.

• 23-11) Kumar, P. , Seerwani, N. , Laloraya, M. , Nivsarkar, M. , Verma, S. , Singh, A.: Superoxide dismutase as a regulatory switch in mammalian testicular ster. oidogenesis. Biochem. Biophys. Res. Commun. 173 (1): 302-308, 1990.

• 23-12) Misra, B. R. , Misra, H. P.: Vasoactive intestinal peptide, a singlet oxygen quencher. J. Biol. Chem. 265 (16): 15371-15374, 1990.

• 23-13) Engstrom, G. W. , Koszewski, N. J.: Metabolism of vitamin D3 in pig liver homogenates-Evidence for a free radical reaction. Arch. of Biochem. Biophys. 270 (2): 432-440, 1990.

第24章 癌と活性酸素

P.404 掲載の参考文献

• 24-1) Ito, A. , Watanabe, H. , Naito, M. , Kawashima, K.: Correlation between induction of duodenal tumor by hydrogen peroxide and catalase activity in mice. Gann 75: 17-21, 1984.
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• 24-2) Ito, A. , Watanabe, H. , Naito, M. , Aoyama, H. , Nakagawa, Y. , Fujimoto, N.: Induction of thyroid tumors in (C57BL/6NxC3H/N) Fl mice by oral administration of 9-3', 4', 5', 6'-tetrachloro-O-carboxy-phenyl-6-hydroxy-2, 4, 5, 7-tetraiodo-3-isoxanthone sodium (Food Red105, Rose Bengal B) . J. Natl. Cancer Instit. 77: 277-281, 1986.

• 24-3) Yamanaka, K. , Hasegawa, A. , Sawamura, R. , Okada, S.: Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice. Biochem. Biophys. Res. Commun. 165 (1): 43-50, 1989.
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• 24-4) Weitzman, S. A. , Gordon, L. 1.: Inflammation and cancer-Role of phagocytegenerated oxidants in carcinogenesis. Blood 76 (4): 655-663, 1990.

• 24-5) Hammad, H. , Higashi, T. , Tateishi, N. , Hanatani, M. , Sakamoto, Y.: Lipid peroxidation in the liver of carcinogen-resistant rats. Biochim. Biophys. Acta 1045: 99-106, 1990.
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• 24-6) Blakeborough, M. H. , Owen, R. W. , Bilton, R. F.: Free radical generating mechanisms in the colon-Their role in the induction and promotion of colorectal cancer? Free Rad. Res. Comms. 6 (6): 359-367, 1989.

• 24-7) Eze, M. O. , Hunting, D. J. , Ogan, A. U.: Reactive oxygen production against malaria-A potential cancer risk factor. Medical Hypotheses 32: 121-123, 1990.
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• 24-8) Nair, U. J. , Friesen, M. , Richard, I. , Mac Lennan, R. , Thomas, S. , Bartsch, H.: Effect of lime composition on the formation of reactive oxygen species from areca nut extract in vitro, Carcinogenesis ll (12): 2145-2148, 1990.

• 24-9) Amstad, P. , Crawford, D. , Muehle-matter, D. , Zbinden, I. , Larsson, R. , Cerutti, P.: Oxidant stress induces the proto-oncogenes, c-fos and c-myc in mouse epidermal cells. Bull. Cancer 77: 501-502, 1990.

• 24-10) Liehr, J. G. , Roy, D.: Free radical generation by redox cycling of estrogens. Free Rad. Biol. & Med. 8: 415-423, 1990.
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• 24-11) Oberley, T. D. , Allen, R. G. , Schultz, J. L. , Lauchner, L. J.: Antioxidant enzymes and steroid-induced proliferation of kidney tubular cells. Free Rad. Biol. & Med. 10: 79-83, 1991.
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• 24-12) Inoue, S. , Kawanishi, S.: Hydroxyl radical production and human DNA damage induced by ferric nitrilo-triacetate and hydrogen peroxide. Cancer Res. 47: 6522-6527, 1987.

• 24-13) Hamazaki, S. , Okada, S. , J. -Lili. , Toyokuni, S. , Midorikawa, O.: Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrotriacetate. Arch. of Biochem. Biophys. 272 (1): 10-17, 1989.

• 24-14) 中野勝輝, 岡田 茂, 豊國伸哉, 翠川 修:臭素酸カリウムおよび鉄ニトリロ三酢酸のウイスターラットへの慢性経口投与による腎の組織学的変化. 内科宝函 36(2): 41-47, 1989.

• 24-15) Nakatsuka, S. , Tanaka, H. , Namba, M.: Mutagenic effects of ferric nitrilotriacetate (Fe-NTA) on V79 Chinese hamster cells and its inhibitory effects on cell-cell communication. Carcinogenesis 11 (2): 257-260, 1990.
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• 24-16) Nicotera, T. M. , Notaro, J. , Notaro, S. , Schumer, J. , Sandberg, A. A.: Elevated SOD in Bloom's syndrome: Agenetic condition of oxidative stress. Cancer Res. 49: 5239-5243, 1989.

• 24-17) Lee, K. -H. , Abe, S. , Yanabe, Y. , Matsuda, I. , Yoshida, M. C.: SOD activity and chromosome damage in cultured chromosome instability syndrome cells. Mutation Res. 244: 251-256, 1990.
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• 24-17a) Mulder, T. P. J. , Verspaget, H. W. , Janssens, A. R. , de Bruin, P. A. F. , Griffioen, G. , Lamers, C. B. H. W.: Neoplasia-related changes of two copper/zinc proteins in the human colon. Free Red. Biol. & Med. 10: 501-506, 1990.

• 24-18) Kawaguchi, T. , Takeyasu, A. , Matsunobu, K. , Uda, T. , Ishizawa, M. , Suzuki, K. , Nishiura T. , Ishikawa, M. , Taniguchi, N.: Stimulation of Mn-SOD expression by tumor necrosis factor一α. Biochem. Biophys. Res. Commun. 171 (3): 1378-1386, 1990.

• 24-19) Baud, L. , Affres, H. , Perez, J. , Ardaillou, R.: Reduction in tumor necrosis factor binding and cytotoxicity by hydrogen peroxide. J. of Immunol 145 (2): 556-560, 1990.
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• 24-20) Galeotti, T. , Wohlrab, H. , Borrello, S. , De Leo, E.: Messenger RNA for Mn-and Cu, Zn-SOD in hepatomas-Correlation with degree of differentiation. Biochem. Biophys. Res. Commun. 165 (2): 581-589, 1989.

• 24-21) Sinha, B. K. , Mimnaugh, E. G.: Free radicals and anticancer drug resistance-Oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors. Free Rad. Biol. & Med. 8: 567-581, 1990.
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• 24-22) Hauser, G. J. , Mclntosh, J. K. , Travis, W. D. , Rosenberg, S. A.: Manipulation of oxygen radical-scavenging capacity in mice alters host sensitivity to tumor necrosis factor toxicity but does not interfere with its antitumor efficacy. Cancer Res. 50: 3503-3508, 1990.

• 24-23) Aune, T. M. , Pierce, C. W.: Conversion of soluble immune response suppressor to macrophage-derived suppressor factor by peroxide. Proc. Natl. Acad. Sci. USA 78 (8): 5099-5103, 1981.
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• 24-24) Issels, R. D. , Nagele, A. , B6ning, B. , Bourier, S. , Wilmanns, W.: Thiol-compounds as thermosensitizer-Experimental results. Strahlentherapic und Onkologie 163 (7): 420-421, 1987.

• 24-25) 斉藤 聡, 佐藤達資・他: Cis-diammine-dichloroplatinum (II) の腎毒性に対する Dopamine の予防効果. 弘前医学 42:93-100, 1990.

• 24-26) Feher, J. , Chihara, G. , Vallent, K. , Deak, G. , Blazovics, A. , Gergely, P. , Kaneko, Y.: Effect of lentinan on SOD enzyme activity in vitro, Immunopharmacology and Immunotoxicology 11 (1): 55-61, 1989.
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• 24-27) Higuchi, Y. , Shoin, S. , Matsukawa, S.: Active oxygen-mediated cytotoxic and antitumor actions of Streptococcal cytotoxic protein. JPn. J. Cancer Res. 81: 169-175, 1990.
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• 24-28) Mashiba, H. , Matsunaga, K.: Augmented antiproliferative effect of tumor necrosis factor (TNF), lymphotoxin and glycyrrhizin in combined use with diethyldithio carbamate on MethA tumor cells in vitro. Japan. J. Exp. Med. 60 (2): 67-71, 1990.

• 24-29) Sekaki, A. , Gardes-Albert, M. , Houee-Levin, C. , Ferrandini, C. , Rivalle, C. , Bisagni, E. , Croisy, A. , Hichel, B.: Role of the superoxide anion in the oxidative activation of the new antitumor drug BD40-A radiolysis study. Int. J. Radiat. Biol. 55 (6): 901-911, 1989.

• 24-30) Pritsos, C. A. , Keyes, S. R. , Sartorelli, A. C.: Effect of the SOD inhibitor, diethyldithiocarbamate on the cytotoxicity of mitomycin antibiotics. Cancer Biochem. Biophys. 10: 289-298, 1989.

• 24-31) Singh, R. J. , Feix, J. B. , Kalyanaraman, B.: Photobleaching of merocyanine 540-Involvement of singlet oxygen. Pasadena Abst. 8. 18, 1990.

• 24-32) Oseroff, A. R. , Ohuoha, D. , Ara, G. , McAuliffe, D. , Foley, J. , Cincotta, L.: Intramitochondrial dyes allow selective in vitro photolysis of carcinoma cells. Proc. Natl. Acad. Sci. USA 83: 9729-9733, 1986.
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• 24-33) Yamamoto, S. , Nakadate, T. , Aizu, E. , Kato, R.: Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic SOD. Carcinogenesis 11 (5): 749-754, 1990.

第25章 増殖・変異・分化と活性酸素

P.419 掲載の参考文献

• 25-1) Shibanuma, M. , Kuroki, T. , Nose, K.: Induction of DNA replication and expression of proto-oncogene c-myc and c-fos in quiscent Balb/3T3 cells by xanthine/xanthine oxidase. Oncogene 3: 17-21, 1988.

• 25-2) Shibanuma, M. , Kuroki, T. , Nose, K.: Superoxide as signal for increase in intracellular pH. J. of Cellular Physiol. 136: 379-383, 1988.
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• 25-3) Smith, P.: Effect of hypoxia upon the growth and sprouting activity of cultured aortic endothelium from the rat. J. of Cell Sci. 92: 505-512, 1989.

• 25-4) Murrell, G. A. C. , Francis, M. J. O. , Bromley, L.: Modulation of fibloblast proliferation by oxygen free radicals. Biochem. J. 265: 659-665, 1990.

• 25-5) Burdon, R. H. , Gi11, V. , Rice-Evans, C.: Cell proliferation and oxidative stress. Free Rad. Res. Comms. 7 (3-6): 149-159, 1989.

• 25-6) Rush, D. N. , McKenna, R. M. , Walker, S. M. , Bakkestad-Legare, P. , Jeffrey, J. R.: Catalase increase Iymphocyte proliferation in mixed lymphocyte culture. Transplantation Proc. 20 (6): 1271-1273, 1988.

• 25-7) Stirpe, F. , Higgins, T. , Tazzari, P. L. , Rozengurt, E.: Stimulation by xanthine oxidase of 3T3 Swiss fibroblasts and human lymphocytes. Exptl. Cell Res. 192: 635-638, 1991.
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• 25-8) Honda, S. , Matsuo, M.: Relationships between the cellular glutathione level and in vitro life span of human diploid fibroblasts. Experimental Gerontology 23: 81-86, 1988.
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• 25-9) Chan, T. M. , Chen, Y. -X. , Brown, A.: Oxidant-mediated effects on protein and phospholipid phosphorylation. Pasadena Abst. 11. 2, 1990.

• 25-9a) Flamigni, F. , Guarnieri, C. , Caldarera, C. M.: Rat liver cytosol contains NADPH and GSH-dependent factors able to restore ornithine decarboxylase inactivated by removal of thiol reducing agents. Biochem. J. 250: 53-58, 1988.

• 25-10) Sugimoto, H. , Matsuzaki, S. , Hamana, K. , Nagamine, T. , Yamada, S. , Suzuki, M. , Kobayashi, S.: SOD andα-tocopherol suppress the paraquat-induced elevetion of N'-acetylspermidine and putrescine in primary culture of adult rat hepatocytes. Life Sci. 45: 2365-2372, 1989.

• 25-11) Hamilton, J. A. , Veis, N. , Bordun, A. -M. , Vairo, G. , Gonda, T. J. , Phillips, W. A.: Activation and proliferation signals in murine macrophages: Relationships among c-fos and c-myc expression, phosphoinositide hydrolysis, superoxide formation, and DNA synthesis. J. of Cellul. Physiol. 141: 618-626, 1989.

• 25-12) Tohyama, C. , Nishimura, H. , Nishimura, N.: Changes in the immunohistological localization of metallothionein under physiological conditions. J. Pharmacobio-Dyn. 13: S-12, 1990.

• 25-13) Anderson, D. , Phillips, B. J. et al.: Effects of active oxygen species on the genetic apparatus. Mutation Res. Special Issue 214 (1), 1989.

• 25-14) Matsuoka, A. , Matsui, M. , Miyata, N. , Sofuni, T. , Ishidate, Jr. M.: Mutagenicity of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites in short-term tests in vitro. Mutation Res. 241: 125-132, 1990.

• 25-15) Sakai, A. , Sasaki, K. , Mizusawa, H. , Ishidate, Jr. M.: Effects of quercetin, a plantflavonol, on the two-stage transformation in vitro. Teratogenesis, Carcinogenesis, and Mutagenesis 10: 333-340, 1990.

• 25-16) IIen, R. G.: Oxygen-reactive species and antioxidant responses during development-The metabolic paradox of cellular differentiation. Proc. of Soc. for Exptl. Biol. and Med. PSEBM. 196: 117-129, 1991.

• 25-17) Auwerx, J. H. , Chait, A. , Wolfbauer, G. , Deeb, S. S.: Loss of Cu, Zn-SOD gene expression in differentiated cells of myelo-monocyte origin. Blood 74 (5): 1870-1810, 1989.

• 25-18) Saito, H. , Kuroki, T. , Nose, K.: Decrease in Cu, Zn-SOD mRNA level during differentiation of human monocytic and promyelotic leukemia cells. FEBS Letts. 249 (2): 253-256, 1989.

• 25-19) Little, G H. , Flores, A.: Changes in the rate of production of superoxide anion in tails of Rana catesbeiana tadpoles during spontaneous and triiodothyronineinduced metamorphosis. Comp. Biochem. Physiol. 96B (2): 315-318, 1990.

• 25-20) Sasaki, F. , Kinoshita, T. , Takahama, H. , Watanabe, K.: Cytochemical studies of hydrogen peroxide production in the tadpole tail of Rana japonica during metamorphic climax. Histochem. J. 20: 99-107, 1988.
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第26章 薬害・公害と活性酸素

P.430 掲載の参考文献

• 26-1) Imura, N. , Naganuma, A. , Satoh, M. , Chen, J. -T.: Trace elements as useful tools for cancer chemotherapy, in "Essential and Toxic Trace Elements in Human Health and Disease" (Alan R. Liss. Inc. 1988), p443-456.

• 26-2) de Jong, J. , Schoofs, P. R. , Onderwater, R. C. A. , van der Vijgh, W. J. F. , Pinedo, H. M. , Bast, A.: Isolated mouse atrium as a model to study anthracycline cardiotoxicity-The roIe of theβ-adrenoceptor system and reactive oxygen species. Res. Commun. in Chem. Pathol. and Pharmacol. 68 (3): 275-289, 1990.

• 26-3) Chacon, E. , Acosta, D.: Mitochondrial regulation of superoxide by Ca2+-An alternate mechanism for the cardiotoxicity of doxorubicin. Toxicol and Applied Pharmacol. 107: 117-128, 1991.

• 26-4) Kojima, S. , Inoue, T. , Kiyozumi, M. , Shimada, H.: Protective effect of N-benzyl-D-glucamine dithiocarbamate against cis-diammine dichloro-platinum-induced toxicity in gastro-intestinal tract and bone marrow in rats. Chem. Pharm. Bull. 38 (11): 3127-3129, 1990.

• 26-5) Cohen, J. D. , Robins, H. I.: Cytotoxicity of diethyldithiocarbamate in human versus rodent cell lines. Investigational New Drugs 8: 137-142, 1990.
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• 26-6) Baldew, G. S. , McVie, J. G. , van der Valk, M. A. , Los, G. , de Goeij, J. J. M. , Vermeulen, N. P. E.: Selective reduction of cis-diamminedichloroplatinum (II) nephrotoxicity by Ebselen. Cancer Res. 50 (1): 7031-7036, 1990.

• 26-7) Rubin, R. L. , Curnutte, J. T.: Metabolism of procainamide to the cytotoxic hydroxylamine by neutrophils activated in vitro. J. Clin. Invest. 83: 1336-1343, 1989.

• 26-8) Pollak, P. T. , Sharma, A. D. , Carruthers, S. G.: Relation of amidarone hepatic and pulmonary toxicity to serum drug concentrations and SOD activity. The Am. J. of Cardiol. 65: 1185-1191, 1990.

• 26-9) Welch, W. D.: Halothane reversibly inhibits human neutrophil bactericidal killing. Anesthesiology 55: 650-654, 1981.
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• 26-10) Welch, W. D.: Effect of enflurane, isoflurane, and nitrous oxide on the micro bicidal activity of human polymorphonuclear leukocytes. Anesthesiology 61: 188-192, 1984.

• 26-11) Nakagawara, M. , Takeshige, K. , Takamatsu, J. , Takahashi, S. , Yoshitake, J. , Minakami, S.: Inhibition of superoxide production and Ca2+mobilization in human neutrophils by halothane, enflurane and isoflurane. Anesthesiology 64: 14-12, 1986.

• 26-12) 小田嘉明, 甲斐広文, 高浜和夫, 宮田 健: 気管支炎病態の進展における気道表面の過 酸化脂質量及び抗酸化酵素活性の変動. 薬学雑誌 110 (8): 612-616, 1990.

• 26-13) Fujimaki, H. , Shiraishi, F. , Wakampri, K.: An antioxidant agent prevents NO2-induced inhibition of mast cell mediator release-Evidence that the mechanism involves free radicals. Environmental Res. 53: 168-174, 1990.

• 26-14) 長野哲雄:活性酸素生成と制御及び活性発現に関する生物有機化学的研究. 薬学雑誌 111(2):103-119, 1991.

• 26-15) Klockars, M. , Hedenborg, M. , Koistinen, J. , Isobe, T.: IgG and IgA enhance the chrysotile-induced production of reactive oxygen metabolites by human polymorphonuclear leucocytes. Clin. exp. Immunol. 78: 372-377, 1989.
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• 26-16) Marsh, J. P. , Mossman, B. T.: Role of asbestos and active oxygen species in activation and expression of ornithine decarboxylase in hamster tracheal epithelial cells. Cancer Res. 51: 167-173, 1991.
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• 26-17) Vuk-Pavlovi6, Z. , Rohrbach, M. S.: Modulation of inflammatory cell function by cotton bract tannin-Changes in the capacity of alveolar macrophages and neutro phils to produce hydrogen peroxide. Am. J. Respir. Cell Mol. Biol. 3: 235-243, 1990.

• 26-18) Khan, S. , Krishnamurthy, R. , Pandya, K. P.: Generation of hydroxyl radicals during benzene toxicity. Biochem. Pharmacol. 39 (8): 1393-1395, 1990.
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第27章 放射線での活性酸素生成と熱ショック蛋白

P.445 掲載の参考文献

• 27-1) Marini, M. , Zunica, G. , Tamba, M. , Cossarizza, A. , Monti, D. , Franceschi, C.: Recovery of human lymphocytes damaged withγ-radiation or enzymatically produced oxygen radicals. Int. J. Radiat. Biol. 58 (2): 279-291, 1990.

• 27-2) Verma, S. P. , Rastogi, A.: Role of proteins in protection against radiation-induced damage in membranes. Radiation Res. 122: 130-136, 1990.
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• 27-3) Rose, R. C.: Ascorbic acid metabolism in protection against free radicals. Biochem. Biophys. Res. Commun. 169 (2): 430-436, 1990.
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• 27-4) Tyrrell, R. M. , Keyse, S. M. , Lautier, D. , Applegate, L.: Inducible cellular defense against oxidative stress in cultured human cells. Pasadena Abst. 1. 3, 1990.

• 27-5) Buc-Calderon, P. , Roberfroid, M.: Increase in the survival time of mice exposed to ionizing radiation by a new class of free radical scavengers, Experientia 46: 708-711, 1990.
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• 27-6) 岡本和人:放射線の生体への有益可能性に関する国際会議. 日本物理学会誌 41(4): 359-362, 1986.

• 27-7) Feinendegen, L. E. , Miihlensiepen, H.: Intracellular stimulation of biochemical control mechanisms by low-dose, low-let irradiation. Health Physics. 52 (5): 663-669, 1987.

• 27-8) 坂本澄彦, 宮本美彌子, 渡辺信之:癌と化学療法 14(5):pt II, 1545-1549, 1987.

• 27-9) 山岡聖典, 石井敬一郎, 武藤徳男, 枝松 礼, 森 昭胤:低線量照射の生体機能に及ぼす影響-ラット免疫器官におけるSOD様活性. 第31回日本放射線影響学会 (広島) 講演要旨集, 1988.

• 27-10) 永田和宏:熱ショック蛋白質の新発展. 実験医学 6(9):831-833, 1988.

• 27-11) Donati, Y. R. A. , Slosman, D. O. , Polla, B. S.: Oxidative injury and the heat shock response. Biochem. Pharmacol. 40 (12): 2571-2577, 1990.
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• 24-12) Salo, D. C. , Donovan, C. M. , Davies, K. J. A: Induction of HSP70 and other heat shock or oxidative stress proteins during exercise. Pasadena Abst. 1. 25, 1990.

• 27-13) Lin, S. W. , Davies, K J. A.: On the regulation of gene expression during Ecoli adaptation to hydrogen peroxide. Pasadena Abst. 1. 26, 1990.

• 27-14) Rokutan, K. , Thomas, J. A. , Sies, H.: Role of specific protein S-thiolation under oxidative stress. Pasadena Abst. 11. 6, 1990.

• 27-15) Storz, G. , Tartaglia, L. A. , Ames, B. N: Transcriptional regulators of oxidative stress-inducible gene-Direct activation by oxidation. Science 248: 189-194, 1990.
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• 27-16) Tao, K. , Makino, K. , Yonei, S. , Nakata, A. , Shinagawa, H.: Purification and characterization of the E. coli OxyR protein, the positive regulator for a hydrogeninducible regulon. J. Biochem. 109: 262-266, 1991.

• 27-17) Maridonneau-Parini, I. , Clerc, J. , Polla, B. S.: Heat shock inhibits NADPH oxidase in human neutrophils. Biochem. Biophys. Res. Commun. 154 (1): 179-186, 1988.
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• 27-18) Sato, M.: Dose-dependent increase in metallothionein synthesis in the lung and liver of paraquat-treated rats. Toxicol. and Applied Pharmacol. 107: 98-105, 1991.

• 27-19) Stocker, R.: Induction of haem oxygenase as a defence against oxidative stress. Free Rad. Res. Comms. 9 (2): 101-112, 1990.

• 27-20) Shibahara, S. , Mtiller, R. M. , Taguchi, H.: Transcriptional control of rat hemeoxygenase by heat shock. J. Biol. Chem. 262 (27): 12889-12892, 1987.

• 27-21) Taketani, S. , Sato, H. , Yoshinaga, T. , Tokunaga, R. , Ishii, T. , Bannai, S.: Induction in mouse peritoneal macrophage of 34 kDa stress protein and heme oxygenase by sulfhydryl-reactive agents, J. Biochem. 108: 28-32, 1990.
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• 27-22) Keyse, S. M. , Applegate, L. A. , Tromvoukis, Y. , Tyrrell, R. M.: Oxidant stress lead to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts. Mol. and Cellul. Biol. 10 (9): 4967-4969, 1990.

第28章 活性酸素による蛋白分解

P.455 掲載の参考文献

• 28-1) Giulivi, C. , Davies, K. , J. A.: An antioxidant role for hemoglobin. Pasadena Abst. 2. 6, 1990.

• 28-2) Pacifici, R. E. , Davies, K. J. A.: Selective proteolysis of oxidatively modified proteins by macroxy-protein (MOP) . Pasadena Abst. 9. 3, 1990.

• 28-3) 小林信彦, 木村 光:活性酸素によるタンパク質の酸化的修飾の機構とその生理作用. 化学 45(7):498-499, 1990.

• 28-4) Manning, M. C. , Patel, K. , Borchardt, R. T.: Stability of protein pharmaceuticals. Pharmaceutical Res. 6 (11): 903-918, 1989〔review〕.
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• 28-5) Manthey, M. K. , Pyne, S. G. , Truscott, R. J. W.: Mechanism of reaction of 3-hydroxyanthranilic acid with molecular oxygen. Biochem. Biophys. Acta 1034: 207-212, 1990.

• 28-6) Uchida, K. , Kato, Y. , Kawakishi, S.: Anovel mechanism for oxidative cleavage of prolyl peptides induced by the hydroxyl radical. Biochem. Biophys. Res. Commun. 169 (1): 265-271, 1990.

• 28-7) Shimogawa, K. , Muto, S.: Active oxygen induced protein ubiquitination in Chlamydomonas. FEBS Letts. 278 (2): 261-262, 1991.

• 28-8) Conetti, A. , Angeletti, M. , Fioretti, E. , Ascoli, F.: Selective oxidation of methionine residues in Kunitz-type protease inhibitors. Biol. Chem. Hoppe-Seyler 370: 723-728, 1989.

• 28-9) Maier, K. L. , Matejkova, E. , Hinze, H. , Leuschel, L. , Weber, H. , Beck-Speier, I.: Different selectivities of oxidants during oxidation of methionine residues in the α-1-proteinase inhibitor. FEBS Letts. 250 (2): 221-226, 1989.

• 28-10) Nowak, D. , Ruta, U.: Nicotine inhibits α-1-proteinase inhibitor inactivation by oxidants derived from human polymorphonuclear leukocytes. Exp. Pathol. 38: 249-255, 1990.

• 28-11) Baker, M. S. , Green, S. P. , Goss, N. , Katrantzis, M. , Doe, W. F.: Plasminogen activator inhibitor 2 (PAI-2) is not inactivated by exposure to oxidants which can be released from activated neutrophils. Biochem. Biophys. Res. Commun. 166 (2): 993-1000, 1990.

• 28-12) kahashi, M. , Yoneda, Y. , Kuriyama, K.: Enhancement ofγ-aminobutyric acid GABA) receptor binding by lipophilic antioxidants. Brain Res. 296: 164-167, 1984.

• 28-13) Yoneda, Y. , Kuriyama, K. , Takahashi, M.: Modulation of synaptic GABA receptor binding by membrane phospholipids-Possible role of active oxygen radicals. Brain Res. 333: 111-122, 1985.
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• 28-14) Hariton, C. , Jadot, G. , Michelson, A M. , Mandel, P.: Superoxide dismutase treatment reduces〔3H〕flunitrazepam affinity in cortex and hippocampus of the rat. Neurosci. Lett. 102: 313-318, 1989.

• 28-15) Haenen, G R. M. M. , Veerman, M. , Bast, A.: Reduction of p-adrenoceptor function by oxidative stress in the heart. Free Rad. Biol. & Med. 9: 279-288, 1990.

• 25-16) Kaneko, M. , Lee, S. -L. , Wolf, C. M. , Dhalla, N. S.: Reduction of calcium channel antagonist binding sites by oxygen free radicals in rat heart. J. Mol. Cell Cardiol. 21: 935-943, 1989.

• 28-17) Matalon, S. , Beckman, J. S. , Duffey, M. E. , Freeman, B. A.: Oxidant inhibition of epithelial active sodium transport. Free Rad. Biol. & Med. 6: 557-564, 1989.
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• 28-18) Hinshaw, D. B. , Armstrong, B. C. , Burger, J. M. , Beals, T. , Hyslop, P. A.: ATP and microfilaments in cellular oxidant injury. Am. J. Pathol. 132: 479-488, 1988.
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第29章 活性酸素による酵素の失活

P.470 掲載の参考文献

• 29-1) Stadtman, E. R.: Metal ion-catalyzed oxidation of proteins Biochemical mechanism and biolobical consequences, Free Rad, Biol, &Med, 9:315-325, 1990.

• 29-2) Thorburn, D. R. , Beutler, E.: Decay of hexokinase during reticulocyte maturation-Is oxidative damage a signal for destruction? Biochem, Biophys, Res, Commun, 162(2):612-618, 1989.
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• 29-3) Levine, R. L. Climent, I. , Farber, J. M. , Shames, B. D. , Sahakian, J. A. , Rivett, A. J.: Metal catalyzed oxidation of glutamine synthetase occurs at the enzyme's active site, Pasadena Abst. 9. 4, 1990.

• 29-4) Bercovich, Z. , Rosenberg-Hasson, Y. , Ciechanover, A. , Kahana, C.: Degradation of ornithine decarboxylase in reticulocyte lysate is ATP-dependent but ubiquitin-independent, J Biol, Chem. , 264(27): 15949-15952, 1989.
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• 29-5) Milstien, S. , Dorche, C. , Kaufman, S.: Studies on the interaction of a thiol-dependent hydrogen peroxide scavenging enzyme and phenylalanine hydroxylase. Arch. of Biochem. Biophys. 282(2):346-351, 1990.
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• 29-6) Palmer, G. C.: Free radicals generated by xanthine oxidase-hypoxanthine damage adenylate cyclase and ATPase in gerbil cerebral cortex. Metabolic Brain Disease 2(4):243-257, 1987.
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• 29-7) Thomas, P. D. , Poznansky, M. J.: Lipid peroxidation inactivates rat liver microsomal glycerol-3-phosphate acyl transferase, J. Biol. Chem. 265(5):2684-2691, 1990.
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• 29-8) Chevalier, M. , Lin, E. C. C. Levine, R. L.: Hydrogen peroxide mediates the oxidative inactivation of enzymes following switch from anaerobic to aerobic metabolism in Klebsiella pneumoniae, J. Biol, Chem, 265(1): 40-46, 1990.

• 29-9) Hinshaw, D. B. , Burger, J. M. , Omann, G. M. , Hyslop, P. A.: H202 can exert toxic effects on endothelial cell independent of ATP synthetic path ways. Pasadena Abst. 11, 21, 1990.

• 29-10) Gardner, P. R. , Fridovich, I.: Superoxide sensitivity of the Escherichia coli 6-phosphogluconate dehydratase, J. Biol. Chem. 266(3):1478-1483, 1991.
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• 29-11) Gardner, P. R. , Fridovich, I.: Quinolinate phosphoribosyl transferase is not the oxygen-sensitive site of nicotinamide adenine dinucleotide biosynthesis. Free Rad, Biol, & Med, 8:117-119, 1990.

• 29-12) McCord, J. M. , Russell, W. J.: Superoxide inactivates creatine phosphokinase during reperfusion of ischemic heart, "Oxy-Radicals in Mol, Biol, and Pathol. " (ed, Cerutti, P. A. , Fridovich, i. , McCord, J. M. , Liss, Alan R. Inc, 1988)p 27-35.

• 29-13) Rao, P. S. , Rujiparn, N. , Weinstein, G. S. , Luber Jr, J. M. , Tyras, D. H.: Effect of oxygen free radicals and lipid peroxides on cardiac isoenzymes, Biomed. Biochim. Acta 49:439-443, 1990.

• 29-14) Terada, L. S. , Beehler, C. J. , Banerjee, A. , Brown, J. M. , Grosso, M. A. , Harken, A. H. , McCord, J. M. , Repine. J. E.: Hyperoxia and self-or neutrophil-generated O2 metabolites inactivate xanthine oxidase. J. Appl. Physiol. 65(5): 2349-2353, 1988.
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• 29-15) Terada, L. S. , Leff, J. A. , Guidot, D. M. Willingham. I. R. Repine, J. E.: Inactivation of xanthine oxidase by hydrogen peroxide involves site-directed hydroxyl radical formation Free Rad. Biol. & Med, 10:61-68, 1991.
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• 29-16) Pigeolet, E. , Corbisier, P. , Houbion, A. , Lambert, D. , Michiels, C. , Raes, M. , Zachary, M. -D. , Remacle, J.: Mechanisms of Ageing and Development 51:283-297, 1990.
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• 29-17) Salo, D. C. , Pacifici, R. E. , Lin, S. W. , Giulivi, C. Davies, K. J. A.: Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation, J. Biol. Chem. 265(20):11919-11927, 1990.

• 29-18) SandstrOm, B. E. , Marklund, S. L.: Effects of variation in glutathiome peroxidase activity on DNA damage and cell survival in human cells exposed to hydrogen peroxide and t-butyl hydroperoxide. Biochem. J. 271:17-23, 1990.

• 29-19) Murata, T. , Hatayama, I. , Satoh, K. , Tsuchida, S. , Sato, K.: Activation of rat glutathione transferases in class mu by active oxygen species. Biochem. Biophys. Res. Commun. 171(2):845-851, 1990.

• 29-20) Hunter, E. P. V. , Desrosiers, M. F. , Simic, M. G.: The effect of oxygen. antioxidants. and superoxide radical on tyrosine phenyl radical dimerization. FreeRad. Biol. & Med. 6:581-585, 1989.

• 29-21) Shimokawa, T. , Kulmacz, R. J. , Dewitt, D. L. Smith, W. L.: Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclo-oxygenase catalysis. J. of Biol. Chem. 265(33):20073-20076, 1990.
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• 29-22) Kulmacz, R. J. , Ren, Y.: Prostaglandin H synthase-Spectroscopic studies of theinteraction with hydroperoxides and with indomethacin, Biochemistry 29:8760-8771, 1990.

• 29-23) Verma, S. , Kumar, P. G. , Laloraya, M. , Singh, A.: Activation of iodine into a freeradical intermediate by superoxide-A physiologically significant step in theiodination of tyrosine. Biochem. Biophys. Res. Commun. 170(3):1026-1034, 1990.

• 29-24) Fetterer, R. H. , Rhoades, M. L.: Tyrosine-derived cross-linking amino acids in thesheath of Haemonchus contrtus infective larvae. J. Parasitol. 76(5):619-624, 1990.

• 29-25) 吉田龍太郎:スーパーオキシゲナーゼ, 蛋核酵 33(16), 特集「活性酸素」(中野 稔, 浅田浩二, 大柳善彦・編, 共立出版, 1988), p3048-3053.

• 29-26) Christen, S. , Peterhans, E. Stocker, R.: Antioxidant activities of some tryptophanmetabolites-Possible implication for inflammatory diseases, Proc, Natl, Acad, Sci, USA 87:2506-2510, 1990.

• 29-27) Uchida, K. Enomoto, N. , Ikakura, K. , Kawakishi, S.: Oxidation reaction of aminoacid derivatives catalyzed by copper (II)and iron (III)conplex, Proc. of the 3rd Symp. on Roles of Metals in Biol. Reactions. Biol. and Med. June 8, 9, 1989(Tokyo).

• 29-28) Ishii, T. , Iwahashi, H. , Sugata, R. , Kido, R. , Fridovich, I.: Superoxide dismutaseenhances the rate of autoxidation of 3-hydroxyanthranilic acid. Arch. Biochem. Biophys. 276(1):248-250, 1990.
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第30章 核酸・糖の合成分解と活性酸素

P.483 掲載の参考文献

• 30-1) Ames, B. N.: Endogenous oxidative DNA damage, Aging and Cancer. Free Rad. Res. Comms. 7(3-6):121-128, 1989.

• 30-2) Spragg, R. G.: DNA strand break formation follwing exposure of bovine pulmonary artery and aortic endothelial cells to reactive oxygen products. Am. J. Respir. Cell Mol. Biol. 4:4-10, 1991.

• 30-3) Tachon, P.: DNA single strand breakage by H202 and ferric or cupric ions. Free Rad. Res. Comms, 9(1):39-47, 1990.

• 30-4) Tachon, P.: Intracellular iron mediates the enhancing effect of histidine on thecellular killing and clastogenicity induced by H202. Mutation Res. 228:221-228, 1990.

• 30-5) Yamamoto, K. , Kawanishi, S.: Site-specific DNA damage induced by hydrazine inthe presence of manganese and copper ions, J. Biol. Chem. 266(3):1509-1515, 1991.

• 30-6) 柏村直樹:糖質と活性酸素, 蛋核酵 33(16), 特集「活性酸素」(中野 稔, 浅田浩二, 大柳善彦・編, 共立出版, 1988), p464-474.

• 30-6a) 柏村直樹, 森田潤司:蛋白質, 核酸のメイラード反応と酸素ラジカルの生成, フリーラ ジカルの臨床, vol. 5(近藤元治監修, 大柳善彦, 吉川敏一編, 日本医学館, 1990), p41- 49.

• 30-7) Metcalfe, D. D. , Thompson, H. L. , Klebanoff, S. J. , Henderson Jr, W. R.: Oxidativedegradation of rat mast-cell heparin proteoglycan, Biochem. J. 272:51-57, 1990.

• 30-8) Reichard, P. , Ehrenberg, A.: Ribonucleotide reductase a radical enzyme. Science 221:514-519, 1983.
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• 30-9) Prince, R. G. , George, G. N.: Tryptophan radicals, Trends in Biol. Sci. 15:170-172, 1990.

• 30-10) Nordlund, P. , Sj6berg, B. -M. , Eklund, H.: Three-dimensional structure of the freeradical protein of ribonucleotide reductase, Nature 345:593-599, 1990.

• 30-11) Hongslo, J. K. , Bjorge, C. , Schwarze, P. E. , Brogger, A. , Mann, G. , Thelander, L. , Holme, J. A.: Paracetamol inhibits replicative DNA synthesis and induces sisterchromatid exchange and chromosomal aberrations by inhibition of ribonucleotide reductase. Mutagenesis 5(5):475-480, 1990.

• 30-12) Ochiai, E. , Mann, G. J. , Graslund, A. , L. Thelander: Tyrosyl free radical formation in the small subunit of mouse ribonucleotide reductase. J. Biol. Chem. 265(26):15758-15761, 1990.

• 30-13) Wright, J. A. , Chan, A. K. , Choy, B. K. , Hurta, R. A. R. , Mc Clarty, G. A. , Tagger, A. Y.: Regulation and drug resistance mechanism of mammalian ribonucleotidereductase and the significance to DNA synthesis. Biochem. Cell Biol. 68:1364-1371, 1990.

• 30-14) Liermann, B. , Lassman, G. , Lanben, P.: Quenching of tyrosine radicals of M2 subunit from ribonucleotide reductase in tumor cells by different antitumoragents-An EPR study. Free Rad. Biol. & Med. 9:1-4, 1990.

• 30-15) Spector, T. , Harrington, J. A. , Porter, D. J. T.: Herpes and human ribonucleotide reductases. Biochem. Pharmacol. 42(1):91-96, 1991.

• 30-16) Cosentino, G. , Guindon, Y. et al.: Specific inhibition of ribonucleotide reductase bypeptides corresponding to the C-terminal of their second subunit. Biochem. CellBiol. 69:79-83, 1991.

• 30-17) Matsumoto, M. , Fox, J. G. , Wang, P. -H. , Koneru, P. B. , Lien, E. J. , Cory, J. G.: Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29cells and mouse leukemia L1210 cells by N-hydroxy-N'-amino-guanidinederivative. Biochem. Pharmacol. 40(8):1779-1783, 1990.

第31章 XODの反応・変動・阻害剤

P.499 掲載の参考文献

• 31-1) Jarasch, E-D. , Grund, C. , Bruder, G. Heid, H. W. , Keenan, T. W. , Franke, W. W.: Localization of xanthine oxidase in mammary gland epithelium and capillaryendothelium. Cell 25:67-82, 1981.

• 31-2) Betz, A. L.: Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries, J. of Neurochemistry 44:574-579, 1985.

• 31-3) McCord, J. M. , Fridovich, I.: The reduction of cytochrome c by milk xanthineoxidase. J. Biol. Chem. 243(21):5753-5760, 1968.

• 31-4) Kito, M. , Tawa, R. , Takeshima, S. , Hirase, S.: Simultaneous assay of hypoxanthine, xanthine and allourinol by high-performance liquid chromatography andactivation of immobilized xanthine oxidase as an enzyme reactor. Chem. Pharm. Bull. 37(9):2459-2462, 1989.

• 31-5) Terada, L. S. , Leff, J. A. , Repine, O. ), Academic Press, 1990, p651-656.

• 31-6) de Jong, J. W. , Van der Meer, P. , Nieukoop, A. S. , Huizer, T. , Stroeve, R. J. , Bos, E.: Xanthine oxidoreductase activity in perfused heart of various spacies including humans. Circ. Res. 67:770-773, 1990.

• 31-7) Paler-Martinez, A. , Panus, P. , Freeman, B.: Role of xanthine oxidase in theformation and release of reactive oxygen species from cultured vascular endothelium. Pasadena Abst. 10. 31, 1990.

• 31-8) Kooij, A. , Bosch, K. S. , Frederiks, W. M. , van Noorden, C. J. F.: Histochemicaldetection of xanthine oxidoreductase activity in endothelial epithelial and connective tissue cells in rat. Pasadena Abst. 2. 29, 1990.

• 31-9) Bruder, G. , Jarasch, E. -D. , Heid, H. W.: High concentrations of antibodies toxanthine oxidase in human and animal sera. J. Clin. Invest. 74:783-794, 1984.

• 31-10) Lewis, W. H. P. , Ng, Y. L. E: Human xanthineoxidase antibody levels-Variation between males and femeles in Chinese and Europeans. Med. Lab. Sci. 48:84-88, 1991.

• 31-11) Graham, K. , Fleming, J. E. , Young, R. Bensch, K. G.: Preparation of antibodiesagainst xanthine oxidase from human milk, Int, J. Biochem, 21(7):715-722, 1989.

• 31-12) Tazzari, P. L. Battelli, M. G. , Abbondanza, A. , Dinota, A. , Rizzi, S. , Gobbi, M. , Stirpe, F.: Targeting of a plasma cell line with a conjugate containing xanthineoxidase and the monoclonal antibody 62B1. Transplantation 48(1):119-122, 1989.

• 31-13) Baret, A. , Fert, V. , Aumaille, J.: Application of long-term enhanced xanthineoxidase-induced luminescence in solid-phase immunoassays, Analytical Biochem. 187:20-26, 1990.

• 31-14) Fert, V. , Baret, A.: Preparation and characterization of xanthine oxidase-antibody and-hapten conjugates for use in sensitive chemiluminescent immunoassays. J. of Immunological Method. 131:237-247, 1990.

• 31-15) Berman, P. A. M. , Human, L.: Regulation of 5-phosphoribosyl 1-pyrophosphateand of hypoxanthine uptake and release in human erythrocytes by oxypurinecycling. J. Biol. Chem. 265(12):6562-6568, 1990.

• 31-16) Ullrich, V. , BrUne, B. , Hecker, G. Schmidt, K. -U. Miilsch, A. , Russe, R.: Physiological targets of superoxide anion and hydrogen peroxide in perfusion injury. FreeRad. Res. Comms. 7(3-6):265-274, 1989.

• 31-17) Ginevri, F. , Ghiggeri, G. et al.: Renal purine efflux and xanthine oxidase activityduring experimental nephrosis in rats-Difference between puromycin aminonucleoside and adriamycin nephrosis. Clin. Sci. 78:283-293, 1990.

• 31-18) Salaris, S. C. , Babbs, C. F. , Guerciolini, M. , Weinshilbouor, R. W. D. , Voorhees II I. W. D.: MDA production during ischemia and reoxygenation of human liver tissue, Pasadena Abst. 10. 36, 1990.

• 31-19) Rodell, T. C. , Cheronis, J. C. , Ohnemus, C. L. , Piermattei, D. J. , Repine, J. E.: Xanthine oxidase mediates elastase-induced injury to isolated Iungs and endothelium. J. Appl. Physiol. 63(5):2159-2163, 1987.

• 31-20) Smith, J. K. , Carden, D. L. Korthuis, R. J.: Role of xanthine oxidase in postischemic microvascular injury in skeletal muscle. Am. J. Physiol, 257: H1782-1789, 1989.
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• 31-21) Sakahara, H. , Satoh, A. , Kato, N.: Increased activity of liver xanthine oxidase inrats from increasing dietary calcium. Agric. Biol. Chem. 54(11):3041-3042, 1990.

• 31-22) Waintrub, M. L. Terada, L. S. , Beehler, C. J. , Anderson, B. O. , Leff, J. A. , Repine, J. E.: Xanthine oxidase is incresed and contributes to paraquat-induced acute lunginjury. J. Appl, Physiol 68(4):1755-1757, 1990.

• 31-23) Akaike, T. , Ando, M. , Oda, T. , Doi, T. , Ijiri, S. , Araki, S. , Maeda, H.: Dependenceon O2 generation by xanthine oxidase of pathogenesis of influenza virus infectionin mice. J. Clin, Invest. 85: 739-745, 1990.

• 31-24) Faur6, M. , Lissi, E. A. , Videlo, L. A.: Antioxidant capacity of allopurinol in biological systems, Biochemistry Int'l. 21(1):357-366, 1990.

• 31-25) Kjaexe, J. , Vell, T. , Bjertnaes, L.: Allopurinol inhibits hypoxic pulmonaryvasoconstriction-Role of toxic oxygen metabolites. Acta Anaesthesiol. Scand. 34:384-388, 1990.

• 31-26) Ko, K. M. , Bodin, D. V.: Inhibition of transition metal ion-catalysed ascorbateoxidation and lipid peroxidation by allopurinol and oxypurinol. Biochem Pharmacol. 40(4):803-809, 1990.

• 31-27) Spector, T. , Hall, W. W. , Porter, D. J. T. , Lambe, C. V. , Nelson, D. J. , Krenitsky, T. A.: Inhibition of xanthine oxidase by 4-hydroxy-6-mercaptopyrazolo [3, 4-d] pyrimidine. Biochem. Pharmacol. 38(23):4315-4320, 1989.

• 31-28) Bundgaard, H. , Jensen, E. Falch, E. , Pedersen, S. B.: Allopurinol prodrug, V, Water-soluble N-substituted(aminomethyl)benzoyloxymethyl allopurinol derivatives for parenteral or rectal delivery. International J. of Pharmaceutics 64:75-87, 1990.

• 31-29) Nakanishi, T. , Nishi, M. , Inada, A. , Obaoa, H. , Tanabe, N. , Abe, S. , Wakashiro, M.: Two new potent inhibitors of xanthine oxidase from leaves of Perilla frulescenscens Britton var. Acuta Kudo. Chem. Pharm. Bull. 38(6):1772-1774, 1990.

• 31-30) Satoh, A. , Ogata, K. , Ota, Y. , Kato, N.: Decreased activity of xanthine oxidase inrat liver by feeding with di-(2-ethylhexyl) phthalate and clofibrate. Agric. Biol. Chem. 54(10):2745-2746, 1990.

• 31-31) Howell, L. L. , Morse, W. H. , Spealman, R. D.: Respiratory effects of xanthines andadenosine analogs in Rhesus monkeys. J. of Pharmacol. and Expt'l. Therap, 254(3):786-791, 1990.

• 31-32) Zong, Z. , Lemasters, J. J. , Thurman, R. G.: Role of purines and xanthine oxidasein reperfusion injury in perfused rat liver. J. of Pharmacol and Expt'l. Therap. 250(2):470-475, 1989.

• 31-33) Huizer, T. , de Jong, J. W. , Nelson, J. A. , Czarnecki, W. , Serruys, P. W. , Bonnier, J. J. R. M. Troquay, R.: Urate production by human heart. J. Mol. Cell Cardiol. 21:691-695, 1989.

• 31-34) Parks, D. A. , Tan, S. , Wheat, J. K. , Evans, A.: Uric acid-Physiologic antioxidantand xanthine oxidase inhibitor. Pasadena Abst. 10. 33, 1990.

• 31-35) Grootveld, M. , Halliwell, B.: Measurement of allantonin and uric acid in humanbody fluid, Biochem. J. 243:803-808, 1987.

第32章 虚血 - 再灌流・炎症とXOD

P.513 掲載の参考文献

• 32-1) Podzuweit, T. , Braun, W. , Miiller, A. Schaper, W.: Arrhythmias and infarction inthe ischemic pig heart are not mediated by xanthine-derived free radicals. BasicRes. in Cardiology 82:493-505, 1987.

• 32-2) McKelvey, T. G. , Hollwarth, M. E. Granger, D. N. , Engerson, T. D. , Landler, U. , Jones, H. P.: Mechanisms of conversion of xanthine dehydrogenase to xanthineoxidase in ischemic rat liver and kidney. Am. J. Physiol. 254:G753-760, 1988.

• 32-3) Kinuta, Y. , Kimura, M. , Itokawa, Y. , Ishikawa, M. Kikuchi, H.: Changes inxanthine oxidase in ischemic rat brain. J. Neurosurg. 71:417-420, 1989.

• 32-4) Tsushima, R. G. , Moffat, M. P.: Concentration-dependent effect of purine/xanthine oxidase on release of 6-keto-PGF1α and contractile function of isolated guineapig heart. J. of Cardiovascular Pharmacol. 14:560-569, 1989.

• 32-5) Thompson-Gorman, S. L. , Zweier, J. L.: Evaluation of the role of xanthine oxidasein myocardial reperfusion injury. J. Biol. Chem. 265(12):6656-6663, 1990.

• 32-6) Friedl, H. P. , Smith, D. J. , Till, G. O. , Thomson, P. D. , Louis, D. S. , Ward, F. A.: Ischemia-reperfusion in humans-Appearance of xanthine oxidase activity. Am. J. of Pathol. 136(3):491-495, 1990.

• 32-7) Elsayed, N. M. , Tierney, D. F.: Hyperoxia and xanthine dehydrogenase/oxidaseactivities in rat lung and heart. Arch. of Biochem. Biophys. 273(2):281-286, 1989.
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• 32-8) Parks, D. A. , Williams, T. K. , Beckman, J. S.: Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine-A reevaluation. Am. J. Physiol. 254:G768-774, 1988.
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• 32-9) Meyer, W. , Kretschmer, M. , Harisch, G.: Regional histochemicaI aspects of xanthine oxidase activity in ischemic and reperfused small intestine of the rat. Cellul. and Mol. Biol. 35(3):357-365, 1989.

• 32-10) de Groot, H. , Littauer, A.: Reoxygenation injury in isolated hepatocytes-Celldeath precedes conversion of xanthine dehydrogenase to xanthine oxidase. Biochem. Biophys. Res. Commun. 155(1):278-282, 1988.

• 32-11) Yokoyama, Y. , Beckman, J. S. , Beckman, T. K. , Wheat, J. K. , Cash, T. G. , Freeman, B. A. , Parks, D. A.: Circulating xanthine oxidase-Potential mediator ofischemic injury. Am. J. Physiol. 258:G564-570, 1990.

• 32-12) Ishii, K. Suita, S. , Sumimoto, H.: Effect of verapamil on conversion of xanthinedehydrogenase to oxidase in ischemic rat liver. Res. Exp. Med. 190:389-399, 1990.

• 32-13) Cighetti, G. , Del Puppo, M. , Paroni, R. , Kienle, M. G.: Lack of conversion ofxanthine dehydrogenase to xanthine oxidase during warm renal ischemia, FEBSLetts. 274(1/2):82-84, 1990.

• 32-14) Mink, R. B. , Dutka, A. J. , Kumaroo, K. K. , Hallenbeck, J. M.: No conversion ofxanthine dehydrogenase to oxidase in canine cerebral ischemia. Am. J. Physiol. 259:H1655-1659, 1990.
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• 32-15) Reiners, Jr. J. J. , Rupp, T.: Conversion of xanthine dehydrogenase to xanthineoxidase occurs during keratinocyte differentiation. J. Invest. Dermatol. 93:132-135, 1989.

• 32-16) 天谷吉宏, 西野武士:キサンチン"脱水素"酵素 D-O 変換, 医学のあゆみ 154(12):754, 1990.
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• 32-17) Hattori, Y.: Localization of xanthine dehydrogenase in chicken liver. ActaHistochem. Cytochem. 22(6):617-624, 1989.

• 32-18) Friedl, H. P. , Guerra, E. E. Cramer, T. , Giacherio, D. , Toledo-Pereya, L. H. , Till, G. O.: Histamine and xanthine oxidase in hepatic ischemia-reperfusion inj ury, Transplantation Proc. 22(2):513-515, 1990.

• 32-19) Phan, S. H. , Gannon, D. E. Varani, J. , Ryan, U. S. , Ward, P. A.: Xanthine oxidaseactivity in rat pulmonary artery endothelial cells and its alteration by activatedneutrophils. Am. J. of Pathol 134(6):1201-1211, 1989.

• 32-20) Stark, K. Seubert, P. , Lynci, G. , Baudry, M: Proteolytic conversion of xanthinedehydrogenase to xanthine oxidase-Evidence against a role for calcium-activatedprotease(Calpain). Biochem. Biophys. Res. Commun. 165(2):858-864, 1989.

• 32-21) Jaeschke, H.: Oxidant stress during acetoaminophen-induced hepatotoxicity-Protection by allopurinol. Pasadena Abst. 2. 24, 1990.

• 32-22) Gruber, D. F. , O'Halloran, K. P. , Farese, A. M: Xanthine oxidase potentiation ofreactive oxygen intermediates in isolated canine peripheral neutrophils. J. of Biol. Response Modifiers. 8:462-467, 1989.

• 32-23) Grum, C. M. , Gross, T. J. , Mody, C. H. , Sitrin, R. G.: Expression of xanthineoxidase activity by murine leukocytes. J. Lab. Clin. Med. 116:211-218, 1990.

• 32-24) Allen, R. E. , Claxson, A. W. D. , Blake, D. R. , Morris, C. J.: Inhibition of xanthineoxidase by allopurinol-Its lack of effect on models of inflammation. Annals of theRhematic Dis. 49(6):422-423, 1990.

• 32-25) Till, G. O. , Guilds, L. S. , Mahrougui, M. , Friedl, H. P. , Trentz, O. , Ward, P. A.: Role of xanthine oxidase in thermal injury of skin. Am. J. of Pathol. 135(1):195-202, 1989.

• 32-26) Friedl, H. P. , Till, G. O. , Trentz, O. , Ward, P. A.: Role of histamine. complementand xanthine oxidase in thermal injury of skin. Am. J. of Pathol. 135(1):203-217, 1989.

• 32-27) 堂園晴彦, 中村和男, 本屋敏郎, 中村佐知子, 新村亮二, 三輪勝洋, 石橋丸応, 永田行 博:癌化学療法時にみられる口内炎の予防. 癌と化学療法 16(10):3449-3451, 1989.

• 32-28) Cooney, J. , Veale, D. , McQuillan, R. , Leahy, A. , Barton, J. , McMahon, M. , Bouchier-Hayes, C. , Courtney, G. , Doyle, J. S. , FitzGerald, O.: Allopurinol prevents non-steroidaI anti-inflammatory drug(NSAID)-induced peptic ulcer disease. Israel J. Med. Sci. 160(1):35, 1991.

第33章 ヘパリンとEC-SOD

P.538 掲載の参考文献

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• 33-3) Gore, I. , Larkey, B. J.: Functional activity of aortic mucopolysaccharides. J. Lab. Clin. Med. 56(6):839-846, 1960.

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• 33-5) Liao, N. St. John, J. , McCarthy, J. B. , Furcht, L. T. , Cheung, H. T.: Adhesion oflymphoid cell to the carboxyl-terminal heparin-binding domains of fibronectin. Expt'l Cell Res. 18:348-361, 1989.

• 33-6) Watanabe, J. , Muranishi, H. , Nakagaki, H. , Yuasa, H. , Ozaki, S.: Macromoleculemacromolecule interaction in drug distribution. Chem. Pharm. Bull. 38(10):2821-2824, 1990.

• 33-7) Lesilie, C. C. , Voelker, D. S. , Channon, J. Y. , Wall, M. M. , Zelarney, P. T.: Properties and purification of an arachidonyl-hydrolyzing phospholipase A2 fromamacrophage cell line. Raw 264. 7. Biochim. Biophys. Acta 963:476-492, 1988.

• 33-8) Brotherton, T. W. , Jagannadham, M J. , Ginder, G. D.: Heparin binds to intactmononucleosomes and induces a novel unfolded structure. Biochemistry 28:3518-3525, 1989.

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• 33-11) Okada, T. , Bark, D. H. , Mayberg, M. R.: Local anticoagulation without systemiceffect using a polymer heparin delivery system. Stroke 19:1470-1476, 1988.

• 33-12) Hjalmarsson, K. , Marklund, S. L. Engstrdn, A. , Edlund, T.: Isolation and sequenceof complementary DNA encoding human extracellular superoxide dismutase. Proc. Natl. Acad. Sci. USA 84:6340-6344, 1987.

• 33-13) Karlsson, K. , Marklund, S. L.: Extracellular superoxide dismutase in the vascularsystem of mammals. Biochem. J. 255:223-228, 1988.

• 33-14) Karlsson, K. , Marklund, S. L.: Plasma clearance of human extracellular-superoxide dismutase C in rabbits. J Clin. Invest. 82:762-766, 1988.
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• 33-15) Adachi, T. , Marklund, S. L.: Interactions between human extracellular superoxide dismutase C and sulfated polysaccharides. J. Biol. Chem. 264(15):8537-8541, 1989.

• 33-16) Karlsson, K. Marklund, S. L.: Binding of human extracellular-superoxide dismutase C to cultured cell lines and to blood cells. Lab. Invest. 60(5):659-666, 1989.
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• 33-16a) Karlsson, K. , Lindahl, U. Marklund, S. L.: Binding of human EC-SOD C to sulphated glycosaminoglycans. Biochem. J. 256:29-33, 1988.

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• 33-18) 大柳善彦:炎症と虚血における EC-SOD とヘパリン. フリーラジカルの臨床, vol. 5(近藤元治監修, 大柳善彦, 吉川敏一編, 日本医学館, 1990), p79-91.

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• 33-22) Hansson, R. , Thysell, H.: The effect of heparin and some related agents ondiamine oxidase in rabbit blood plasma. Acta Physiol. Scand. 78:539-546, 1970.
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• 33-23) Persson, E. Nilsson-Ehle, P.: Release of lipoprotein lipase and hepatic lipaseactivities-Effects of heparin and low molecular weight heparin fragment. Scand. J. Clin. Lab. Invest. 50:43-49, 1990.
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• 33-24) Freeman, B. A. , Whitfield, K. , Gelman, D. , Parks, D. A.: Heparin-reversiblebinding of xanthine oxidase to vascular endothelium. Pasadena Abst. 10. 15, 1990.

• 33-25) Rosenman, R. H. , Solomon, B. , Byers, S. , Friedman, M.: Arresting effect of heparin upon experimental nephrosis in rats. Proc. Soc. Exp. Biol. Med. 86:599-603, 1954.

• 33-26) Quinkler, W. , Maasberg, M. , Bernotat-Danielowski, S. , Lifthe, N. Sharma, H. S.: Isolation of heparin-binding growth factors from bovine, porcine and canine hearts. Eur. J. Biochem. 181:67-73, 1989.

• 33-27) Lecomte, J. , Hugues, J.: Action inhibitrice de l'heparine sur le phenomene d'Arthus. Int. Arch. Allergy 5:367-373, 1954.

• 33-28) Carr, J. , Ch, M. B.: The anti-inflammatory action of heparin-Heparin as an antagonist to histamine, bradykinin and prostaglandin E1. Thrombosis Res. 16:507-516, 1979.

• 33-29) Brestel, E. P. , Koes, M. T.: Heparin inhibits the "Quasi-lipoxygenase" activity of hemoglobin toward lipoleic acid by oxidant scavenging. Prostaglandins Leukotriens and Essential Fatty Acids 36:21-24, 1989.

• 33-30) Lider, O. , Baharav, E. Mekori, Y. A. , Miller, T. , Naparstek, Y. , Vlodavsky, I. , Cohen, I. R.: Suppression of experimental auto-immune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins. J. Clin. Invest. 83:752-756, 1989.

• 33-31) Tanaka, T. , Tsujinaka, T. , Kambayashi, J. , Higashiyama, M. , Yokota, M. , Sakon, M. , Mori, T.: The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model. Thrombosis Res. 60:321-330, 1990.

• 33-31a) Flick, M. R. , Hoeffel, J. M. , Staub, N. C.: Superoxide dismutase with heparin prevents increased lung vascular permeability during air emboli in sheep. J . Appl. Physiol. 55(4):1284-1291, 1983.

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• 33-34) Jaques, L. B.: Drug prophylaxis in atherosclerosis. Artery 14:209. . 215, 1987.

• 33-35) Shulman, A. G.: Heparin and atherosclerosis-An investigative report on the treatment of atherosclerosis. Biomed. & Pharmacother. 44:303-306, 1990.
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• 33-36) Hiebert, L. M. Liu, J.: Heparin protects cultured arterial endothelial cells from damage by toxic oxygen metabolites. Atherosclerosis 83:47-51, 1990.
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• 33-37) Engelberg, H.: Heparin therapy of severe coronary atherosclerosis with observation of its effect on angina pectris, the two-step electrocardiogram and the balli-stocardiogram. Am. J. of the Med. Sci. 224:487-495, 1952.

• 33-38) Hobson II. RW. , Neville, R. , Watanabe, B. , Canady, J. , Wright, J. G. , Belkin, M.: Role of heparin in reducing skeletal muscle infarction in ishemia-reperfusion. Microcirc. Endothelium Lymphatics 5(3-5):259-276, 1989.

• 33-39) Ejiri, M. , Fujita, M. , Miwa, K. , Hirai, T. , Yamanishi, K. , Sakai, O. , Ishizaka, S. , Sasayama, S.: Effect of heparin treatment on collateral development and regionalmyocardial function in acute myocardial infarction. Am. Heart J. 119:248-253, 1990.
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• 33-40) Dube, L. M. , Davies, R. F. , Beanlands, D. S. , Mousseau, N.: Dissociation of authentic and artifactual effect of circulating heparin on drug Protein binding, Biopharmaceut. & Drug Disposition 10:55-68, 1989.

• 33-41) Kobayashi, S. , Kitazawa, T. , Somlyo, A. V. , Somlyo, A. P.: Cytosolic heparin inhibits muscarinic andα-adrenergic Ca2+ release in smooth muscle. J. Biol. Chem. 264(30):17997-18004, 1989.

• 33-42) Damon, D. H. , Lobb, R. R. , D'Amore, P. A. , Wagner, J. A.: Heparin potentiates theaction of acidic fibroblast growth factor by prolonging its biological half-life. J. Cellul. Physiol. 138:221-226, 1989.

• 33-43) Wright. Jr, T. C. , Pukac, L. A. , Castellot. Jr, J. J. , Karnovsky, M. J. , Levine, R. A. , Kim-Park, H. , Campisi, J.: Heparin suppressess the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway. Proc. Natl Acad. Sci. USA 86:3199-3203, 1989.

• 33-44) Reilly, C. F. , Kindy, M. S. , Brown, K. E. , Rosenberg, R. D. , Sonnenshein, G. E.: Heparin prevents vascular smooth muscle cell progression through the G1 phase of the cell cycle. J. Biol. Chem. 264(12):6990-6995, 1989.

• 33-45) Knaus, H. -G. , Scheffauer, F. Romanin, C. , Schindler, H. -G. , Glossmann, H.: Heparin binds with high affinity to voltage-dependent L-type Ca2+channels. J. Biol. Chem. 265(19):11156-11166, 1990.

• 33-46) Folkman, J. , Langer, R. , Linharctt, R. J. , Haudenschild, C. Taylor, S.: Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone. Science 221:719-725, 1983.

• 33-47) Folkman, J. , Weisz, P. B. , Joullie, M. M. , Li, W. W. , Ewing, W. R.: Control of angiogenesis with synthetic heparin substitutes. Science 243:1490-1493, 1989.
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第34章 心臓, 脳, 血圧に対するCa拮抗剤

P.555 掲載の参考文献

• 34-1) Abel, F. L.: Myocardial function in sepsis and endotoxin shock. Am. J. Physiol. 257:R1265-R1281, 1989.
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• 34-3) Richter, C. , Frei, B.: Ca2+ release from mitochondria induced by prooxidants. Free Rad. Biol. & Med. 4:365-175, 1988.
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• 34-4) Duncan, C. J.: Biochemical events associated with rapid cellular damage during the oxygen and calcium-paradoxes of the mamalian heart. Experientia 46:41-48, 1990.

• 34-5) Hayashi, H. , Miyata, H. , Watanabe, H. , Kobayashi, A. , Yamazaki, N.: Effect of hydrogen peroxide on action potentiaIs and intracellular Ca2+ concentration of guinea pig heart. Cardiovascular Res. 23:767-773, 1989.

• 34-6) van Gilst, W. H. , Scholtens, E. , de Graff, P. A. , de Langen, C. D. J. , Wesseling, H.: Differential influences of angiotensin converting-enzyme inhibitors on the coronary circulation. Circulation 77 (suppl. 1):1-24-29, 1988.

• 34-7) Bagchi, D. , Iyengar, J. , Stockwell, P. , Das, D. K.: Enhanced prostaglandin production in the ischemic-reperfused myocardium by captopril linked with its free radical scavenging action. Prostagl. Leukotr. and Essential Fatty Acids 38:145-150, 1989.

• 34-8) Swies, J. , Omogbai, E. K. I. , Smith, G. M.: Occlusion and reperfusion-induced arrhythmias in rats-Involvement of platelets and effects of calcium antagonists. J. of Cardiovas. Pharmacol. 15:816-825, 1990.

• 34-9) Grover, G. J. , Dzwonczyk, S. , Sleph, P. G.: Comparative anti-ischemic effects of dihydropyridine calcium antagonists in isolated perfused rat heart. Pharmacology 40:137-149, 1990.
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• 34-10) Herbaczynska-Cedro, K. , Lewicki, Z. , Barcikowski, B. , Famulski, K. , Gordon-Majszak, W. , Klos, J. , Wutzen, J. , Ceremuzyfiski, L.: Effect of nisoldipine on stress-induced myocardial damage in the conscious pig. Clin. and Expt. Pharmacol. and Physiol. 17:1-10, 1990.

• 34-11) Herbaczynska-Cedro, K. Gordon-Majszak, W.: Nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium. Cardiovasc. Res. 24:683-687, 1990.
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• 34-12) Sassen, L. M. A. , Bezstarosti, K. , Verdouw, P. D. , Lamers, J. M. J.: Effects ofnisoldipine on recovery of coronary blood flow, ' sarcoplasmic reticulum function and other biochemical parameters in post-ischemic porcine myocardium. Biochem. Pharmacol. 41(1):43-51, 1991.

• 34-13) Das, D. K. , Engelman, R. M. , Prasad, M. R. , Rousou, J. A. , Breyer, R. H. , Jones, R. , Young, H. , Cordis, G. A.: Improvements of ischemia-reperfusion-induced myocar dial dysfunction by modulating calcium-overload using a novel, specific calmodulin antagonist, CGS9343B. Biochem. Pharmacol. 38(3):465-471, 1989.

• 34-14) Nayler, W. G. , Liu, J. , Panagiotopoulos, S.: Nifedipine and experimental cardioprotection. Cardiovasc. Drugs and Therapy 4:879-886, 1990.
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• 34-14a) Weselcouch, E. O. , Demusz, C. D.: Drug effects on function in the ferret ischemic hindlimb. J of Pharmacol Method. 23:255-264, 1990.

• 34-15) Green, C. J. , Gower, J. D. , Healing, G. , Cotterill, L. A. , Fuller, B. J. , Simpkin, S.: The importance of iron, calcium and free radicals in reperfusion injury. Free Rad. Res. Comms. 7(3-6):255-264, 1989.

• 34-16) Takei, Y. , Marzi, I. , Kauffman, F. C. Currin, R. T. , Lemasters, J. J. , Thurman, R. G.: Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine. Transplantation 50(1):14-20, 1990.

• 34-17) Pickford, M. , Sandin, B. , Gower, J. D. , Green, C. J.: The effect of allopurinol and nifedipine on oxidative membrane and functional outcome of rat lung isografts after 48 hour cold storage. Cryo-Letters 11:265-276, 1990.

• 34-18) Keyser, R. O. , Alger, B. E.: Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals. Nleuron 5:545-553, 1990.

• 34-19) Krueger, M. J. , McKeown, K. , Ramsay, R. R. , Youngster, S. K. , Singer, T. P.: Mechanism-based inactivation of monoamine oxidases A and B by tetrahydroridines and dihydropyridines. Biochem. J. 268:219-224, 1990.

• 34-20) 安孫子 尚, 溝井和夫, 鈴木二郎, 大庭正敏, 吉本高志: Ca2+拮抗剤 flunarizine の虚血脳保護作用に関する実験的検討. 脳神経 39(9):847-854, 1987.

• 34-20a) Germano, I. M. , Bartkowski, H. M. , Cassel, M. E. , Pitts, L. H.: The therapeutic value of nimodipine in experimental focal cerebral ischemia. J. Neurosurg. 67:81-87, 1987.

• 34-21) Hara, H. , Nagasawa, H. , Kogure, K.: Nimodipine prevents postischemic brain damage in the early phase of focal cerebral ischemia. Stroke 21(suppl. N):102-104, 1990.

• 34-22) Finger, S. , Green, L. Tarnoff, M. E. , Mortman, K. D. , Andersen, A.: Nimodipine enhances new learning after hippocampal damage. Exptl. Neurology 109:279-285, 1990.

• 34-23) Carta, F. , Bianchi, M. , Argenton, S. , Cervi, D. , Marolla, G. , Tamburini, M. , Breda, M. , Fantoni, A. , Panerai, A. E.: Effect of nifedipine on morphine-induced analgesia. Anesth. Analg. 70:493-498, 1990.
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• 34-24) Sladowska, H. , Bartoszko-Malik, A. , Zawisza, T.: Synthesis and properties of the derivative of 2-alkylthio-4-oxo-3, 4-(and-1, 4)-dihydropyrido-[2, 3-d] pyrimidine-5-and-6-carboxylic acids. I1 Farmaco. 45(1):111-121, 1990.

• 34-25) Miranda, H. F. Paeile, C.: Interactions between analgesics and calcium channel blockers. Gen. Pharmac. 21(2): 171-174, 1990.

• 34-26) McGrath, J. C. , Ugwu, A. C.: Effects of BayK8644 and nifedipine on isolated perfused rat tail artery under different oxygen tensions. Br. J. Pharmacol. 88:385P. 1986.

• 34-27) Goligorsky, M. S.: Role of endothelium in endotoxin blockade of voltage-sensitive Ca2+ channels in smooth muscle cells. Am. J. Physiol. 257:C875-C881, 1989.
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• 34-28) Marriott, J. F.: The effects of verapamil upon noradrenaline-induced contraction of the rat isolated aorta following acute and prolonged alteration in pO2. Br. J. Pharmacol. 98:1101-1108, 1989.

• 34-29) Westlin, W. , Mullane, K.: Does captopril attenuate reperfusion-induced myocardial dysfunction by scavenging free radicals?Circulation 77(suppl. I):30-39, 1988.

• 34-30) Schneider, R. , Iscovitz, H. , Ilan, Z. , Bernstein, K. , Gros, M. , Iaina, A.: Oxygen free radical scavenger system intermediate in essential hypertensive patients before and immediately after sublingual captopril administration. Isr. J. Med. Sci. 26:491-495, 1990.
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• 34-31) 鈴木 光:K+チャネルオープナー, とくに血管平滑筋への作用. 医学のあゆみ 154(2):112, 1990.
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第35章 抗酸化・抗動脈硬化剤としてのCa拮抗剤

P.577 掲載の参考文献

• 35-1) Pang, D. C. , Sperlakis, N.: Uptake of calcium-antagonistic drugs into muscles as related to their lipid solubilities. Biochem. Pharmacol. 33(5):821-826, 1984.

• 35-2) Hirosumi, J. , Ouchi, Y. , Watanabe, M. , Kusunoki, J. , Nakamura, T. , Orimo, H.: Biochem. Biophy. Res. Commun. 152(1):301-307, 1988.
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• 35-3) Franceschi, D. , Graham, D. , Sarasua, M. Zollinger Jr. R. M.: Mechanism of oxygen free radical-induced calcium overlead in endothelial cells. Surgery 108 (2):292-297, 1990.

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• 35-5) Bors, W. , Buetlner, G. R. , Michel, C. , Saran, M.: Calcium in lipid peroxidation-Does calcium interact with superoxide? Arch. Biochem. Biophys. 278(1):269-272, 1990.

• 35-6) Shridi, F. , Robak, J.: The influence of calcium channel blockers on superoxide anions. Pharmacol. Res. Commun. 20(1):13-21, 1988.
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• 35-7) Janero, D. R. , Burgharatt, B. , Lopez, R.: Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists. Biochem. Pharmacol 37 (21):4197-4203, 1988.

• 35-8) Janero, D. R. Burghard, B.: Antiperoxidant effects of dihydropyridine calcium antagonists. Biochem. Pharmacol. 38(23):4344-4348, 1989.

• 35-9) Tong-Mak, I. , Weglicki, W. B.: Comparative antioxidant activities of propranolol, nifedipine, verapamil, and diltiazem against sarcolemmal membrane lipid peroxidation. Circ. Res. 66:1449-1452, 1990.

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• 35-12) Yamada, Y. , Yokota, M. , Furumichi, T. , Furui, H. , Yamauchi, K.: Protective effects of calcium channel blockers on hydrogen peroxide-induced increases in endothelial permeability. Cardiovasc. Res. 24:993-997, 1990.
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• 35-13) Ver Donck, L. Van Reempts, J. , Vandeplassche, G. , Borgers, M.: A new method to study activated oxygen species-induced damage in cardiomyocytes and protection by Ca2+-antagonists. J. Mol. Cell Cardiol. 20:811-823, 1988.
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• 35-14) Ver Donck, L. , Verellen, G. , Vandewiele, R. De Clerck, F. , Borgers, M.: Class IV Ca2+-antagonists do not affect lipid peroxidation in singlet oxygen challenged cardiomyocytes. Cell Biol. Intl. Reports 14(4):399-406, 1990.
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• 35-15) Orrenius, S. McConkey, D. J. , Jones, D. P. , Nicotera, P.: Ca2+-activated mechanisms in toxicity and programmed cell death. ISI Atlas of Sci. Pharcmacol 1988, p319-324.

• 35-16) Watanabe, H. , Kobayashi, A. , Yamamoto, T. , Suzuki, S. , Hayashi, H. , Yamazaki, N.: Alterations of human erythrocyte membrane fluidity by oxygen-derived freeradicals and calcium. Free Rad. Biol. & Med. 9:507-514, 1990.

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• 35-18) 折茂 彰, 大内尉義, 服部明徳, 秋下雅弘, 折茂 肇:抗動脈硬化薬としてのCa拮抗薬の効果. 治療学 24(11):1277-1282, 1990.

• 35-19) 清水伸哉, 田村彰彦, 佐藤慶仁, 林 順子, 勝沼英字:動脈硬化進展におけるCa2+拮抗剤の影響. 薬理と治療 18(suppl. ):S-209-214, 1990.

• 35-20) Nomoto, A. , Hirosumi, J. , Sekiguchi, C. , Mutoh, S. , Yamaguchi, I. , Aoki, H.: Anti atherogenic activity of FR34235(Nilvadipine)-Effect on cuff-induced intimal thickeing of rabbit carotid artery. Atherosclerosis 64:255-261, 1987.

• 35-21) Mutoh, S. , Nomoto, A. , Sekiguchi, C. , Yamaguchi, I.: Protective action of a calcium antaionist, nilvadipine, against aortic calcium deposition. Atherosclerosis 73:181-189, 1988.
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• 35-22) Nomoto, A. , Mutoh, S. , Hagihara, Yamaguchi, I.: Smooth muscle cell migration induced by inflammatory cell products and its inhibition by a potent calcium antagonist, nilvadipine. Atherosclerosis 72:213-219, 1988.
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• 35-23) Del Boccio, G. , Lapenna, D. , Porreca, E. , Kennelli, A. , Savini, F. , Feliciani, P. , Ricci, G. , Cuccurullo, F.: Aortic antioxidant defence mechanisms: time-related changes in cholesterol-fed rabbits. Atherosclerosis 81:127-135, 1990.
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• 35-24) Henry, P. D.: Calcium antagonists as anti-atherosclerotic agents. Atheriosclerosis 10(6):963-965, 1990.

• 35-25) Yamaguchi, Y. , Yamada, K. , Kitagawa, S. , Kunitomo, M.: Atherosclerosis mouse model induced by a high-cholesterol diet supplement withβ-aminopropionitrile. Jap. J. Pharmacol. 54:187-196, 1990.

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• 35-29) Irita, K. , Fujita, I. Takeshige↓K. Minakami, S. , Yoshitake, J.: Calcium channel antagonist induces inhibition of superoxide production in human neutrophils. Biochem. Pharmacol. 35(20):3465-3471, 1986.

• 35-30) Filep, J. B. , F61des-Filep, E.: Inhibition by calcium channel blockers of the binding of platelet-activating factor to human neutrophil granulocytes. Eur. J. of Pharmacol. 190:67-73, 1990.

• 35-31) Karnad, A. B. , Hartshorn, K. L. Tauber, A. I.: Effect of nisoldipine on priming and activation of the human neutrophil respiratory burst. Agents and Actions 31(1/2):79-85, 1990.

• 35-32) Nalini, K. , Andrabi, K. I. , Ganguly, N. K. , Wahi, P. L.: Nifedipine impairs neutrophil respiratory burst by a mechanism other than calcium channel blockade. Mol. and Cellul. Biochem. 93:27-34, 1990.

• 35-33) Nalini, K. , Andrabi, K. I. , Ganguly, N. K. , Wahi, P. L.: Nifedipine administration impairs natural resistance of mice to Salmonell typhimurium. Mol and Cellul. Biochem. 95:133-137, 1990.

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• 35-36) Oyanagui, Y. , Sato, S.: Inhibition by nilvadipine of ischemic and carrageenan pawedema as well as of superoxide radical production from neutrophils and xanthine oxidase. Arzneim. -Forschung-Drug Res. 41(1) Nr 5:469-474, 1991.

• 35-37) Kan, K. S. , Coleman, R.: Menadione increases hepatic tight-junctional permeability-Its effect can be decreased by butylated hydroxytoluene and verapamil. Biochem. J. 270:241-243, 1900.

• 35-38) Golan, A. , Wexler, S. , Lotan, G. , Abramov, L. Langer, R. David, M. P.: Calcium antagonist-Effect on adhesion formation. Acta Obstet. Gynecol. Scand. 68:529-532, 1989.

• 35-39) Joseph, B. Z. , Organek, H. W. , Grant, A. , Axelrod, D. A.: Effects of nifedipine therapy on pulmonary Raynaud's phenomenon in primary Sjogren's syndrome. Clin. and Expt. Rheumatol. 6:409-410, 1988.

• 35-40) Safa, A. R.: Photo-affinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil. Proc. Natl. Acad. Sci. USA 85:7187-7191, 1988.

• 35-41) Twentyman, P. R. Reeve, J. G. , Koch, G. , Wright, K. A.: Chemosensitisation by verapamil and cyclosporin A in mouse tumor cells expressing different levels of Pglycoprotein and CP22(sorcin). Br. J. Cancer 62:89-95, 1990.
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• 35-42) Broxterman, H. J. , Pinedo, H. M. , Schuurhuis, G. J. , Lankelma, J.: Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumor cells. Br. J. Cancer 62:85-88, 1990.
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• 35-43) Nygren, P. , Larsson, R.: Verapamil and cyclosporin A sensitize human kidney tumor cells to vincristine in absence of membrane P-glycoprotein and without apparent changes in the cytoplasmic free Ca2+ concentration. Bioscience Reports 10(2):231-237, 1990.
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• 35-44) Shudo, N. , Mizoguchi, T. , Kiyosue, T. , Arita, M. , Yoshimura, A. , Seto, K. , Sakoda, R. , Akiyama, S.: Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel blocking activity than their dihydropyridine counter parts. Cancer Res. 50:3055-3061, 1990.

• 35-45) Kiue, A. , Sano, T. , Inada, H. , Suzuki, K. , Okumura, M. , Kikuchi, J. , Sato, S. , Takano, H. , Kohno, K. , Kuwano, M.: Reversal by two dihydropyridine compounds of resistance to multiple anticancer agents in mouse P388 leukemia in vivo and in vitro. Jpn. J. Cancer Res. 81:1057-1064, 1990.

• 35-46) K. -Radek, J. , Stepien, H. , Lyson, K. L. Pawlikowski, M.: Effects of calcium channel modulators on the proliferation of mouse spleen Iymphocytes in vitro. Agents and Actions 29(3/4):254-257, 1990.

第36章 鉄での活性酸素生成と鉄キレーターでの治療

P.598 掲載の参考文献

• 36-1) 岡田 茂:鉄代謝と組織細胞障害. BIO medica 5(8):782-787, 1990.

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• 36-4) Brieland, J. K. , Fantone, J. C.: Ferrous iron release from transferrin by human neutrophil-derived superoxide anion-Effect of pH and iron saturation. Arch. of Biochem. Biophys. 284(1):78-83, 1991.
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• 36-5) 中村明人, 曽根三郎, 杉原浩二, 古庄重樹, 棟方正信, 小倉 剛: Transferrinによる lymphokine-activated killer(LAK) 細胞誘導増強作用について. Biotherapy 5(1): 18-23, 1991.

• 36-6) Tiede, R. , Sareen, S. , Singal, P. K.: Transferrin delays oxygen radical induced cardiac-contractile failure. Can. J. Physiol. Pharmacol. 68:480-485, 1990.
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• 36-7) Dautry-Varsat, A. , Ciechanover, A. , Lodish, H. F.: pH and the recycling of transferrin during receptor-mediated endocytosis. Proc. Natl Acad. Sci. USA 80:2258-2262, 1983.
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• 36-9) 漆崎一朗, 高後 裕:トランスフェリンレセプター. 代謝 23(臨時増刊号):187-193, 1986.

• 36-10) Barrand, M. A. , Hider, R. C. Callingham, B. A.: The importance of reductive mechanisms for intestinal uptake of iron from ferric maltol and ferric nitrilotriacetic acid (NTA). J. Pharm. Pharmacol 42:279-282, 1990.
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• 36-11) Ozaki, M. Kawabata, T. , Awai, M.: Iron release from haemosiderin and production of iron-catalysed hydroxyl radicals in vitro. Biochem. J. 250:589-595, 1988.
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• 36-12) Britigan, B. E. Hassett, D. J. , Rosen, G. M. , Hamill, D. R. , Cohen, M. S.: Neutrophil degranulation inhibits potential hydroxyl-radical formation. Biochem. J. 264:447-455, 1989.
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• 36-14) Gutteridge, J. M. C.: Superoxide-dependent formation of hydroxyl radicals from ferric-complexes and hydrogen peroxide-An evaluation of fourteen iron chelators. Free Rad. Res. Comms. 9(2):119-125, 1990.

• 36-15) Hoepelman, I. M. , Bezemer, W. A. Vandenbroucke-Grauls, C. M. J. E. , Marx, J. J. M. , Verhoef, J.: Bacterial iron enhances oxygen radical-mediated killing of Stmphylococcus aureus by phagocytes. Infection and Immunity 58(1):26-31, 1990.

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• 36-18) Singh, R. Pathak, D. N.: Lipid peroxidation and glutathione peroxidase, glutathione reductase, superoxide dismutase, catalase, and glucose-6-phosphate dehydrogenase activities in FeCl3-induced epileptogenic foci in the rat brain. Epilepsia 31(1):15-26, 1990.
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• 36-19) Vollmer, D. G. , Hongo, K. , Ogawa, H. , Tsukahara, T. , Kassell, N. F.: Astudy of the effectiveness of the iron-chelating agent deferoxamine as vasospasm prophylaxis in a rabbit model of subarachnoid hemorrhage. Neurosurgery 28(1):27-32, 1991.

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• 36-22) Pietrangelo, A. , Grandi, R. , Tripodi, A. , Tomasi, A. , Ceccarelli, D. , Ventura, E. Masini, A.: Lipid composition and fluidity of liver, mitochondria, microsomes and plasma membrane of rats with chronic dietary iron overload. Biochem. Pharmacol 39(1):123-128, 1990.
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• 36-23) Goldberg, M. B. , Dirita, V. J. , Calderwood, S. B. , Identification of an iron-regulated virulence determinant in Vibrio cholerae, using Tnpho A mutagenesis. Infection and Imunity 58(1):55-60, 1990.

• 36-24) Iheanacho, E. N. , Samuni, A. , Avramovici-Grisaru, S. , Sarel, S. , Spira, D. T.: Inhibition of Plasmodium falciparum growth by a synthetic iron chelator, Transactions of the Royal Soc. of Tropical Med. and Hygene 84:213-216, 1990.

• 36-25) Hallaway, P. E. , Eaton, J. W. , Panter, S. S. , Hedlund, B. E.: Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers. Proc. Natl. Acad. Sci. USA 86:10108-10112, 1989.
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• 36-26) Hedlund, Bo. E. , Hallaway, P. E.: Fluid resuscitation with a deferoxamine-colloid conjugate-Applications to burn injury and hemorrhagic shock. Pasadena Abst. 16. 12, 1990.

• 36-27) Porter, J.: Oral iron chelators-Prospects for future development. Eur. J. Haematol. 43:271-285, 1989.
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• 36-28) Porter, J.: Oral iron chelators-Prospects for future development. Eur. J. Haematol. 43:271-285, 1989.
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• 36-29) Porter, J. B. , Morgan, J. , Hoyes, K. P. , Burke, L. C. , Huehns, E. R. , Hider, R. C.: Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice. Blood 76(11):2379-2396, 1990.

• 36-30) Wolfe, L. C.: Desferrithiocin. Seminars in Hematology 27(2):117-120, 1990.
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• 36-32) Kennedy, T. P. , Rao, N. V. , Noah, W. , Michael, J. R. , Jafri. Jr. M. H. , Gurtner, G. H. , Hoidal, J. R.: Ibuprofen prevents oxidant lung injury and in vitro lipid peroxidation by chelating iron. J. Clin. Invest. 86:1565-1573, 1990.

• 36-33) Aoki, N. , Lefer, A. M.: Protective effects of a novel nonglucocorsticoid 21-aminosteroid (U74006F) during traumatic shock in rats . J. of Cardiovascular Pharmacol. 15:205-210, 1990.

• 36-34) Bartett, A. N. Hoffbrand, A. V. , Kontoghiorghes, G. J.: Long-term trial with the oral iron chelator 1, 2-dimethyl-3-hydroxypyrid-4-one(L1), -(II) Clinical observations. Br. J. of Haematology 76:301-304, 1990.

• 36-35) Kontoghiorghes, G. J. , Bartlett, A. N. , Hoffbrand, A. V. , Goddard, J. G. , Sheppard L. Barr, J. , Nortey, P.: Long-term trial with the oral iron chelator 1, 2-dimethyl-3-hydroxyprid-4-one(L1)-(I) Iron chelation and metabolic studies. Br. J. of Haematol. 76:295-300, 1990.

• 36-36) Olivieri, N. F. Koren, G. , Hermann, C. , Bentur, Y. , Chung, D. , Klein, J. , St. Louis, P. , Freedman, M. H. , McClelland, R. A. , Templeton, D. M.: Comparison of oral iron chelator L1 and desferrioxamine in iron-loaded patients. The Lancet 336:1275-1279, 1990.

• 36-37) Sheppard, L. Barr, J. , Kontoghiorghes, G. J.: Structure/activity/toxicity correlation of orally activeα-ketohydroxypyridine iron chelators intended for clinical use as antiinflammatory agents. Eur. J. of Clin. Invest. 21(2): Pt II Meeting Abst. 315, 1991.

第37章 諸金属と活性酸素

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• 37-3) Grinstein, S. , Furuya, W. , Lu, D. J. , Mills, G. B.: Vanadate stimulates oxygen consumption and tyrosine phosphorylation in electropermeabilized human neutro-phils. J. Biol. Chem. 265(1):318-327, 1990.

• 37-4) Liochev, S. I. , Fridovich, I.: Vanadate stimulates oxydation of NAD(P) Hin the presence of biogical membranes and other sources of O2-. Arch. Biochem. Biophys. 279(1):1-7, 1990.

• 37-5) Younes, M. , Strubelt, O.: Vanadate-induced toxicity towards isolated perfused rat livers. Toxicology 66:63-74, 1991.
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• 37-6) Shi, X. , Dalal, N. S.: NADPH-dependent flavoenzymes catalyze one electron reduction of metal ions and molecular oxygen and generate hydroxyl radicals. FEBS Letts. 276(1/2):189-191, 1990.

• 37-7) Sakurai, H. , Tsuchiya, K. , Nukatsuka, M. , Sofue, M. , Kawada, J.: Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats. J. of Endocrinology 126:451-459, 1990.

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• 37-9) Murthy, M. S. , Rao, L. N.: Antitumor and toxicological anticancer agent vanadocene dichloride. Inorganica Chemica Acta 152:117-124, 1988.

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• 37-14) Shainkin-Kestenbaum, R. Caruso, C. , Berlyne, G. M.: Effect of nickel on oxygen free radical metabolism. Biological Trace Elment Res. 28:213-221, 1991.

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• 37-17) Hill, C. L. , Weeks, M. S. , Schinazi, R. F.: Anti-HIV-1 activity, toxicity, and stability studies of representative structural families of polyoxometalates. J. of Med. Chem. 33(10):2767-2772, 1990.
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• 37-18) Inoue, Y. , Take, Y. , Tokutake, Y. , Yoshida, T. , Yamamoto, A. , Yamase, T. , Nakamura, S.: Inhibition of replication of human immunodeficiency virus by a heteropolyoxotungstate (PM-19). Chem. Pharm. Bull. 38(1):285-287, 1990.

第38章 NO (EDRF) とスーパーオキシド

P.625 掲載の参考文献

• 38-1) Ignarro, L. J.: Endothelium-derived nitric oxide-Pharmacology and Relationship to the actions of organic nitrate esters. Pharmaceutical Res. 6(8):651-659, 1989.

• 38-2) Collier, J. , Vallance, P.: Second messenger role for NO widens to nervous and immune systems. Trends in Pharmacol. Sci. 10: cover-428-431, 1989.

• 38-3) LUscher, T. R. Bock, H. A. , Yang, Z. , Diederich, D.: Endothelium-derived relaxing and contracting factors-Perspectives in nephrology. Kideny Int'l. 39:575-590, 1991.

• 38-4) Richards, J. M. , Gibson, I. F. Martin, W.: Effects of hypoxia and metabolic inhibitors on production of prostacyclin and endothelium-derived relaxing factor by pig aortic endothelial cells. Br. J. Pharmacol. 102:203-209, 1991.
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• 38-5) 石幡 明, 遠藤政夫: EDRF=NO説をめぐって. 医学のあゆみ 152(1):12-17, 1990.
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• 38-12) Saran, M. , Michel, C. Bors, W.: Reaction of NO with O2: implications for the action of endothelium-derived relaxing factor(EDRF). Free Rad. Res. Comms. 10(4-5):221-226, 1990.

• 38-13) BrUne, B. , Schmidt, K. -U. , Ullrich V.: Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion. Eur. J. Biochem. 192:683-688, 1990.
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• 38-14) Kosaka, H. , Uozumi, M. , Tyuma, I.: The interaction between nitrogen oxides and hemoglobin and endthelium-derived relaxing factor. Free Rad. Biol. & Med. 7:653-658, 1989.
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• 38-15) Miura, Y. , Utsumi, H. , Kashiwagi, M. Hamada, A.: Effects of oxygen on the membrane structure and the metabolism of lipophilic nitroxide in rat liver microsomes. J. Biochem. 108:516-518, 1990.

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• 38-18) Myatt, L. , Brewer, A. , Brockman, D. E.: The action of nitric oxide in the perfused human fetal-placental circulation. Am. J. Obstet. Gynecol. 164:687-692, 1991.
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第39章 NO (EDRF) の生成刺激とその作用

P.643 掲載の参考文献

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• 39-4) Boulanger, C. , Liischer, T. F.:Release of endothelin from the porcine aorta. J. Clin. Invest. 85:587-590-1990.

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• 39-14) Leurs, R. Brozius, M. M. , Jansen, W. , Bast, A. , Timmerman, H.: Histamine H1-receptor-mediated cyclic GMP prduction in guinea-pig lung tissue is an L-arginine-dependent process. Biochem. Pharmacol. 42(2):271-277, 1991.

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• 39-17) Loflon, C. E. , Baron, D. A. , Heffner, J. E. , Currie, M. G. , Newman, W. H.:Atrial natriuric peptide inhibits oxidant-induced increases in endothelial permeability. J. Mol. Cell Cardiol. 23:919-927, 1991.

• 39-18) Salvermini, D. , de Nucci, G. , Gryglewski, R. J. , Vane, J. R.: Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc. Natl. Acad. Sci. USA 86:6328-6332, 1989.

• 39-19) Salvemini, D. , Korbut, R. , Anggard, E. Vane, J.: Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Eschen' chia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA 87:2593-2597, 1990.

• 39-20) Bult, H. , Fret, H. R. L. , Jordaens, F. H. , Herman, A. G.: Dipyridamole potentiates platelet inhibition by nitric oxide. Thrombosis and Haemostasis 66(3):343-349, 1991.

• 39-21) Kubes, P. , Suzuki, M. , Granger, D. N.: Nitric oxide:An endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 88:4651-4655, 1991.
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• 39-22) Whittle, B. J. R. , Lopez-Belmonte, J. , Rees, D. D.: Modulation of the vasopressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation. Br. J. Pharmacol. 98:646-652, 1989.

• 39-23) Katusic, Z. K. , Vanhoutte, P. M.: Superoxide anion is an endothelium-derived contracting factor. Am. J . Physiol. 257:H33-H37, 1989.

• 39-24) Kilbourn, R. G. , Jubran, A. , Gross, S. S. , Griffith, O. W. , Levi, R. , Adams, J. , Ladato, R. F.: Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem. Biophys. Res. Commun. 172(3):1132-1138, 1990.

• 39-25) Lawson, D. L. Mehta, J. L. Nichols, W. W. , Mehta, P. , Donnelly, W. H.:Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings. J. Lab. Clin. Med. 115:541-548, 1990.

• 39-26) Griffith, T. M. , Edwards, D. H.:EDRF in intact vascular networks. Blood Vessels 27:230-237, 1990.
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• 39-27) Persson, M. G. , Gustafsson, L. E. , Wiklund, N. P. , Hedqvist, P. , Moncada, S.: Endogenous nitric oxide as modulator of rabbit skeletal muscle microcirculation in vivo. Br. J. Pharmacol 100:463-466, 1990.
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• 39-28) Persson, M. G. , Wiklund, N. P. , Gustafsson, L. E.: Nitric oxide requirement for vasomotor nerve-induced vasodilatation and modulation of resting blood flow in muscle microcirculation. Acta Physiol. Scand. 141:49-56, 1991.
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• 39-29) Persson, M. G. , Gustafsson, L. E. Wiklund, N. P. , Moncada, S. , Hedqvist, P.: Endogenous nitric oxide as a probable modulator of pulmonary circulation and hypoxic pressor response in vivo. Acta. Physiol. Scand. 140:449-457, 1990.
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• 39-30) Kilbourn, R. G. , Belloni, P.: Endothelial cell production of nitric oxide in response to interferonγin combination with tumor nocrosis factor, interleukin-1, or endotoxin. J. Natl Cancer Inst. 82:772-776, 1990.

• 39-31) Rees, D. D. , Palmer, R. M. J. , Schulz, R. , Hodson, H. F. , Moncada, S.: Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol 101:746-752, 1990.

• 39-32) Gardiner, S. M. , Compton, A. M. Kemp, P. A. , Bennett, T.:Regional and cardiac haemodynamic responses to glyceryl trinitrate, acetylcholine, bradykinin and endothelin-1 in conscious rats. Br. J. Pharmacol. 101:632-639, 1990.
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• 39-33) Moy, J. A. , Bates, Fisher, R. A.: Effects of nitric oxide on platelet-activating factor-andα-adrenergic-stimulated vasoconstriction and glycogenolysis in the perfused rat liver. J. Biol. Chem. 266(13):8092-8096, 1991.

• 39-34) Remuzzi, G. , Perico, N. , Zoja, C. , Corna, D. , Macconi, D. , Vigano, G.: Role of endothelium-derived nitric oxide in the bleeding tendency of uremia. J. Clin. Invest. 86:1768-1771, 1990.
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• 39-35) Zatz, R. , de Nucci, G.: Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am. J. Physiol. 261:F360-F363, 1991.
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• 39-36) Masini, E. , Mannaioni, P. F. , Pistelli, A. , Salvemini, D. , Vane, J.: Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats. Biochem. Biophys. Res. Commun. 177(3):1178-1182, 1991.

• 39-37) Ceriello, A. , Quatraro, A. , Caretta, F. Varano, R. , Giugliano, D.: Evidence for a possible role of oxygen free radicals in the abnormal functional arterial vasomotion in insulin dependent diabetes. Diabete & Metabolisme (Paris) 16:318-322, 1990.

• 39-38) Granger, D. L. Hibbs Jr, J. B. , Broadnax, L. M.: Urinary nitrate excretion in relation to murine macrophage activation. J. of Immunol. 146(4):1294-1302, 1991.

• 39-39) Takagi, K. , Nakagami, H. , Nakano, T. , Suketa, Y.: Induction of nitrite production in mouse spleen cells by immunization. Biochim. Biophys. Acta 1092:15-20, 1991
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• 39-40) Lepoivre, M. , Fieschi, F. , Cover, J. , Thelander, L. , Fontecave, M.: Inactivation of ribonucleotide redutase by nitric oxide. Biochem. Biophys. Res. Commun. 179(1):442-448, 1991.

第40章 NO (EDRF) とcGMP生成機構

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• 40-1) Pohl, U.: Endothelial cells as part of a vascular oxygen-sensing system. -Hypoxia-induced release of autacoids. Experientia. 46:1175-1179, 1990.
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• 40-3) Fleming, I. , Gray, G. A. , Julon-Schaeffer, G. , Parratt, J. R. , Stoclet, J. -C.: Incubation with endotoxin activates the L-arginine pathway in vascular tissue. Biochem. Biophys. Res. Commun. 171(2):562-568, 1990.

• 40-4) Bredt, D. S. , Hwang, P. M. , Snyder, S. H.: Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347:768-770, 1990.
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• 40-5) Hope, B. T. , Michael, G. J. , Knigge, K. M. , Vincent, S. R.: Neuronal NADPH diaphorase is a nitric oxide synthase. Proc. Natl. Acad. Sci. USA 88:2811-2814, 1991.
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• 40-6) De Master, E. G. , Raij, L. , Archer, S. L. Weir, E. K.: Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of Larginine to nitric oxide. Biochem. Biophys. Res. Commun. 163(1):527-533, 1989.

• 40-7) Myers, P. R. , Minor, Jr. R. L. Guerra, Jr. R. , Bates, J. N. , Harrison, D. G.: Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide. Nature 345:161-163, 1990.

• 40-8) Radi, R. , Beckman, J. S. , Bush, K. M. , Freeran, A.: Peroxynitrite oxidation of sulfhydryls-The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266(7):4244-4250, 1991.

• 40-9) Radi, R. Beckman, J. S. , Bush, K. M. , Freeman, B. A.: Arch. of Biochem. Biophys. 288(2):481-487, 1991.
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• 40-10) Wei, E. P. , Kontos, H. A.: H202 and endothelium-dependent cerebral arteriolar dilation-Implication for the identity of endothelium-derived relaxing factor generated by acetylcholine. Hypertension 16:162-169, 1990.

• 40-11) Mulligan, M. S. , Hevel, J. M. , Marletta, M. A. , Ward, P. A.: Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc. Natl. Acad. Sci. USA 88:6338-6342, 1991.

• 40-12) Morrison, K. J. , Pollock, D.: Impairment of relaxations to acetylcholine and NO by a phorbol ester in rat isola ed aorta. Br. J. Pharmacol. 101:432-436, 1990.

• 40-13) Sakuma, I. , Akaishi, Y. , Fukao, M. , Yasuda, H.: Dipyridamole potentiates antiaggregating and vasorelaxing effects of endothelium-derived relaxing factor by the inhibition of cyclic GMP phosphodiesterase. J. Pharmacobio-Dyn. 14:S-17, 1991.

• 40-14) Ignarro, L. J.: Signal transduction mechanisms involving nitric oxide. Biochem. Pharmacol. 41(4):485-490, 1991.
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• 40-15) Goldschmidt, J. E. Tallarida, R. J.: Pharmacological evidence that captopril possesses an endothelium-mediated component of vasodilation. J. of Pharmacol. and Exptl Therapeutics 257(3):1136-1145, 1991.

• 40-16) Cherry, P. D. , Omar, H. A. , Farrell, K. A. , Stuart, J. S. , Wolin, M. S.: Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation. Am. J. Physiol. 259:H1056-H1062, 1990.
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• 40-17) Cherry, P. D. , Wolin, M. S.: Ascorbate activates soluble guanylate cyclase via H202-metabolism by catalase. Free Rad. Biol. & Med. 7:485-490, 1989.

• 40-18) Collier, J. , Vallance, P.: Second messenger role for NO widens to nervous and immune systems. Trends in Pharmacol. Sci. 10: cover-428-431, 1989.

• 40-19) Hecker, M. , Mitchell, J. A. , Swierkosz, T. A. , Sessa, W. C. , Vane, J. R.: Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells. Br. J. Pharmacol. 101:237-239, 1990.
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• 40-20) Swierkosz, T. A. , Mitchell, J. A. , Sessa, W. C. Hecker, M. , Vane, J. R.: L-glutamine inhibits the release of endothelium-derived relaxing factor from the rabbit aorta. Biochem. Biophys. Res. Commun. 172(1):143-148, 1990.
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• 40-21) Hinshaw, D. B. , Burger, J. M.: Protective effect of glutamine on endothelial cell ATP in oxidant injury. J . of Surg. Res. 49:222-227, 1990.
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• 40-22) Hinshaw, D. B. , Burger, J. M. , Delius, R. E. Hyslop, P. A.: Mechanism of protection of oxidant-injured endothelial cells by glutamine. Surgery 108:298-305, 1990.
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• 40-23) Sessa, W. C. , Hecker, M. , Mitchell, J. A. , Vane, J. R.: The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor-L-glutamine inhibits the generation of L-arginine by cultured endothelial cells. Proc. Natl. Acad. Sci. USA 87:8607-8611, 1990.

• 40-24) Hecker, M. , Sessa, W. C. , Harris, H. J. , Anggi rd, E. E. Vane, J. R.: The metabolism of L-arginine and its significance for the biosynnthesis of endothelium-derived relaxing factor-Cultured endothelial cells recycle L-citrulline to L-arginine. Proc. Natl. Acad. Sci. USA 87:8612-8616, 1990.

• 40-25) Mitchell, J. A. , Hecker, M. , Anggi rd, E. E. Vane, J. R.: Cultured endothelial cells maintain their L-arginine level despite the continuous release of EDRF. Eur. J. of Pharmacol. 182:573-576, 1990.

第41章 NO (EDRF) と炎症・動脈硬化

P.678 掲載の参考文献

• 41-1) McCall, T. B. , Boughton-Smith, N. K. , Palmer, R. M. J. , Whittle, B. J. R. , Moncada, S.: Synthesis of nitric oxide from L-arginine by neutrophils-Release and interaction with superoxide anion. Biochem. J. 261:293-296, 1989.

• 41-2) Mehta, J. L. Lawson, D. L. Nichols, W. W. , Mehta, P.: Modulation of vascular tone by neutrophils-Dependence on endothelial integrity. Am. J. Physiol. 257:H1315-H1320, 1989.
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• 41-3) Ohlstein, E. H. , Nichols, A. J.: Rabbit polymorphonuclear neutrophils elicit endothelium-dependent contraction in vascular smooth muscle. Circ. Res. 65:917-924, 1989.
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• 41-4) Sessa, W. C. , Mullane, K. M.: Release of neutrophil-derived vasoconstrictor against which auguments platelet-induced contractions of blood vessels in vitro. Br. J. Pharmacol. 99:553-559, 1990.

• 41-5) Stuehr, D. J. , Fasehun, O. A. , Kwon, N. S. , Gross, S. S. , Gonzalez, J. A. , Levi, R. , Nathan, C. F.: Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. FASEB J. 5:98-103, 1991.
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• 41-6) McCall, T. B. , Feelisch, M. , Palmer, R. M. J. , Moncada, S.: Identification of N-iminoethyl L-ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells. Br. J. Pharmacol. 102: 234-238, 1991.

• 41-7) Heim, K. F. , Thomas, G. , Ramwell, P. W.: Effect of substituted arginine compounds on superoxide production in the rabbit aorta. J. of Pharmacol. and Exptl. Therapeutics 257(3):1130-1135, 1991.

• 41-8) Busse, R. , MUIsch, A.: Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Letts. 275(1/2):87-90, 1990.

• 41-9) Beasley, D.: Interleukin 1 and endotoxin activate soluble guanylate cyclase in vascular smooth muscle. Am. J. Physiol. 259:R38-R44, 1990.
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• 41-10) Cattell, V. , Cook, T. , Moncada, S.: Glomeruli synthesize nitrite in experimental nephrotoxic nephritis. Kidney Intl. 38:1056-1060, 1990.

• 41-11) Hutcheson, I. R. , Whittle, B. J. R. Boughton-Smith, N. K.: Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat. Br. J. Pharmacol. 101:815-820, 1990.

• 41-12) Kroncke, K. -D. , Kolb-Bachofen, V. , Berschick, B. , Burkart, V. , Kolb, H.: Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem. Biophys. Res. Commun. 175(3):752-758, 1991.
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• 41-13) Masini, E. , Salvemini, D. , Pistelli, A. , Mannaioni, P. F. , Vane, J. R.: Rat mast cells synthesize a nitric oxide-like factor which modulates the release of histamine. Agents and Actions 33(1/2):61-63, 1991.

• 41-14) Langrehr, J. , Murase, N. , Cai, X. , Simmons, R. , Hoffman, H.: Nitric oxide production is a marker of rejection of vascularized organ allografts and is inhibited by FK506. Abst. of 1st Intl. Congress FK506(Aug. 21-24, 1991. Lawrence, D. L. -Convention Center, Pittsburgh) No. 87.

• 41-15) Belvisi, M. G. , Stretton, D. , Barnes, P. J.: Nitric oxide as an endogenous modulator of cholinergic neurotransmission in guinea-pig airways. Eur. J. of Pharmacol 198:219-221, 1991.
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• 41-16) Gudgeon, J. R. Martin, W.: Modulation of arterial endothelial permeability. Br. J. Pharmacol. 98:1267-1274, 1989.
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• 41-17) Hughes, S. R. , Williams, T. J. , Brain, S. D.: Evidence that endogenous nitric oxide modulates oedema formation induced by substance P. Eur. J. of Pharmacol. 191:481-484, 1990.
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• 41-18) Duarte, I. D. G. , Lorenzetti, B. B. , Ferreira, S. H.: Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Eur. J. of Pharmacol. 186:289-293, 1990.

• 41-19) MacIntyre, I. , Zaidi, M. , Alam, A. S. M. T. , Datta, H. K. , Moonga, B. S. , Lidbury, P. S. , Hecker, M. , Vane, J. R.: Osteoclastic inhibition-An action of nitric oxide not mediated by cyclic GMP. Proc. Natl. Acad. Sci. USA 88:2936-2940, 1991.

• 41-20) Di Rosa, M. , Radomski, M. , Carnuccio, R. , Moncada, S.: Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochem. Biophys. Res. Commun. 172(3):1246-1252, 1990.
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• 41-21) Knowles, R. G. Salter, M. , Brooks, S. L. , Moncada, S.: Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat. Biochem. Biophys. Res. Commun, 172(3):1042-1048, 1990.
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• 41-22) Radomski, M. W. , Palmer, R. M. J. , Moncada, S.: Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc. Natl. Acad. Sci. USA 87:10043-10047, 1990.

• 41-23) Rees, D. D. , Cellek, S. , Palmer, R. M. J. , Moncada, S.: Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone. Biochem. Biophys. Res. Commun. 173(2):541-547, 1990.

• 41-24) Pfeilschifter, J.: Anti-inflammatory steroids inhibit cytokine induction of nitric oxide synthase in rat renal mesangial cells. Eur. J. of Pharmacol. 195:179-180, 1991
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• 41-25) Mehta, J. L. Lawson, D. L. Nicolini, F. A. , Cain, D. A. , Mehta, P. , Schreier, H.: Evidence for generation of a large amount of nitric oxide-like vascular smooth muscle relaxant by cholesterol-rich neutrophils. Biochem. Biophys. Res. Commun. 173(1):438-442, 1990.
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• 41-26) Bruckdorfer, K. R. , Jacobs, M. Rice-Evans, C.: Endothelium-derived relaxing factor(nitric oxide), lipoprotein oxidation and atherosclerosis. Biochemical Soc. Transactions 18:1061-1063, 1990.

• 41-27) Galle, J. , Mtilsch, A. , Busse, R. Bassenge, E.: Effect of native and oxidized low density lipoproteins on formation and inactivation of endothelium-derived relaxing factor. Arteriosclerosis and Thrombosis 11:198-203, 1991.
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第42章 マクロファージおよび薬剤よりのNO生成

P.693 掲載の参考文献

• 42-1) Iyengar, R. , Stuehr, D. J. , Marletta, M. A.: Macrophage synthesis of nitrite, nitrate, and N-nitrosamines-Precursors and role of the respiratory burst. Proc. Natl. Acad. Sci. USA 84:6369-6373, 1987.

• 42-2) Ding, A. H. , Nathan, C. F. , Stuehr, D. J.: Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages-Comparison of activating cytokines and evidence for independent production. J. of Immunol. 141(7):2407-2412, 1988.
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• 42-3) Tayeh, M. A. , Marletta, M. A.: Macrophage oxidation of L-arginine to nitric oxide, and nitrate-Tetrahydrobiopterin is required as a cofactor. J. Biol. Chem. 264(33):19654-19658, 1989.
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• 42-4) Albina, J. E. , Mills, C. D. , Henry Jr, W. L. Caldwell, M. D.: Regulation of macrophage physiology by L-arginine-Role of the oxidative L-arginine deaminase pathway. J. of Immunol. 143(11):3641-3646, 1989.

• 42-5) Higuchi, M. , Higashi, N. Taki, H. , Osawa, T.: Cytolytic mechanism of activated macrophages-Tumor necrosis factor and L-arginine-dependent mechanisms act synergistically as the major cytolytic mechanisms of activated macrophages. J. of Immunol. 144:1425-1431, 1990.
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• 42-6) 滝 龍雄, 中野昌康:マクロファージにおけるアルギニンおよびその代謝産物による抗菌抗腫瘍作用. 医学のあゆみ 156(3):194-197, 1991.
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• 42-8) Thomsen, L. L. Ching, L-M. , Baguley, B. C.: Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid. Cancer Res. 50:6966-6970, 1990.
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• 42-9) Stadler, J. , Curran, R. D. , Ochoa, J. B. , Harbrecht, B. G. , Hoffman, R. A. , Simmons, R. L. Billiar, T. R.: Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo. Arch. Surg. 126:186-191, 1991.
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• 42-10) Liew, F. Y. , Millott, S. , Parkinson, C. , Palmer, R. M. J. , Moncada, S.: Macrophage killing of leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. of Immunol. 144(12):4794-4797, 1990.

• 42-11) James, S. L. Glaven, J.: Macrophage cytotoxicity agairist schistosomula of Schistosoma monsoni involves arginine-dependent production of reactive nitrogen intermediates. J. of Immunol. 143(12):4208-4212, 1989.

• 42-12) Lefer, A. M. , Aoki, N.: Leukocyte-dependent and leukocyte-independent mechanisms of impairmont of endothelium-mediated vasodilation. BIood Vessels 27:162-168, 1990,

• 42-13) Johnson III. G. Tsao, P. , Lefer, A. M.: Synergism between superoxide dismutase and sodium nitrite in cardioprotection following ischemia and reperfusion. Am. Heart J. 199(3):530-537, 1990.

• 42-14) Mehta, J. L. Nichols, W. W. , Saldeen, T. G. P. , Chandna, V. K. , Nicolini, F. A. , Lawson, D. L. ter Riet, M. F.: Superoxide dismutase decreases reperfusion a rrhythmias and preserves myocardial function during thrombolysis with tissueplasminogen activator. J. of Cardiovascular Pharmacol. 16:112-120, 1990.

• 42-15) Reif, D. W. , Simmons, R. D.: Nitric oxide mediates iron release from ferritin. Arch. of Biochem. Biophys. 283(2):537-541, 1990.
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• 42-16) Wolin, M. S. , Cherry, P. D. , Rodenburg, J. M. , Messina, E. J. , Kaley, G.: Methylene blue inhibits vasodilation of skeletal muscle arterioles to acetylcholine and nitric oxide via the extra-cellular generation of superoxide anion. J. of Pharmacol. and Exptl. Therapeutics 254(3):872-876, 1990.

• 42-17) Bohn, H. , Schonafinger, K.: Oxygen and oxidation promote the release of nitric oxide from sydonominines. J. of Cadiovascular Pharacol. 14(Suppl. 11):S6-S12, 1989.

• 42-18) Feelisch, M. , Ostrowski, J. , Noack, E.: On the mechanism of NO release from sydonimines. J. of Cardiovascular Phamacol. 14(suppl. 11):S13-S22, 1989.

• 42-19) Gerzer, R. , Drummer, C. , Karrenbrock, B. , Heim, J. -M.: Inhibition of platelet activating factor-induced platelet aggregation by molsidomine, SIN-1, and nitrates in vitro and ex vivo. J of Cardiovascular Pharmacol. 14(Suppl. 11):S115-S119, 1989.

• 42-20) Dembifiska-Kiec, A. , Zmuda, A. , Marcinkiewicz, J. , Sinzinger, H. , Gryglewski, R. J.: Influence of NO-donor(SIN-1) on functions of inflammatory cells. Agents and Actions 32(1/2):37-40, 1991.

• 42-21) Sakata, K. , Karaki, H.: Phorbol ester-induced release of endothelium-derived relaxing factor. Eur. J. of Pharmacol. 179:207-210, 1990.
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第43章 循環器系・消化器系とNO

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• 43-2) Hoshida, S. , Yamashita, N. , Igarashi, J. , Nishida, M. , Hori, M. Kameda, T. , Kuzuya, T. , Tada, M.: Nitric oxide synthase protects the heart against ischemiareperfusion injury in rabbits. J. Pharmacol Expt. Therapeutics 274(1):413-418, 1995.

• 43-3) Winlaw, D. S. , Smythe, G. A. , Keogh, A. M. , Schyvens, C. G. , Spratt, P. M. , MacDonald, P. S.: Increased nitric oxide production in heart failure. Lancet 344:373-374, 1994.
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• 43-4) Hartman, J. C.: The role of bradykinin and nitric oxide in the cardioprotective action of ACE inhibitor. Ann. Thorac. Surg. 6(1):789-792, 1995.

• 43-5) Lefer, A. M. , Murohara, T.: Comparative pharmacology of nitric oxide and nitric oxide generator on cardiac contractility in mammalian species. Int. J. of Cardiol. 50:239-242, 1995.

• 43-6) Gardiner, S. M. , Kemp, P. A. Bennett, T. , Palmer, R. M. J. , Moncada, S.: Regional and cardiac haemodynamic effects of NG. NG. dimethyl-L-arginine and their reversibility by vasodilators in conscious rats. Br. J. Pharmacol. 110:1457-1464, 1993.

• 43-7) Shindo, T. , Ikeda, U. , Ohkawa, F. , Takahashi, M. , Funayama, H. , Nishinaga, M. , Kawahara, Y. , Yokoyama, M. , Kasahara, T. , Shimada, K.: Nitric oxide synthesis in rat cardiac myocytes and fibroblasts. Life Sci. 55(11):1101-1108, 1994.

• 43-8) Balligand, J. -L. , Kobzik, L. Han, X. , Kaye, D. M. , Belhassen, L. O'Hara, D. S. , Kelly, R. A. , Smith, T. W. , Michel, T.: Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocyte. J. Biol. Chem. 270(24):14582-14586, 1995.
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• 43-9) Mohan, P. , Brutsaert, D. L. Sys, S. U.: Myocardial performance is modulated by interaction of cardiac endothelium derived nitric oxide and prostaglandins. Cardiovasc. Res. 29:637-640, 1995.
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• 43-10) Vinten-Johansen, Sato, H. , Zhao, Z. Q.: The role of nitric oxide and NO-donor agents in myocardial protection from surgical ischemia-reperfusion injury. Int. J. of Cardiol. 50:273-281, 1995.

• 43-11) Dudek, R. R. , Wildhirt, S. , Conforto, A. , Pinto, V. , Suzuki, H. , Winder, S. , Bing, R. J.: Inducible nitric oxide synthase activity in myocardium after myocardial infarction in rabbit. Biochem. Biophys. Res. Common. 205(3):1671-1684, 1994.

• 43-12) Clarkson, P. B. M. Lim, P. O. , MacDonald, T. M.: Influence of basal nitric oxide secretion on cardiac function in man. Br. J. Clin. Pharmacol. 40:299-305, 1995.

• 43-13) Brunet, J. , Boily, M. -J. , Cordeau, S. , Des Rosiers, C.: Effects of N-acetyl-cysteine in the rat heart perfused after low-flow ischemia. Free Rad. Biol. & Med. 19(5):627-638, 1995.

• 43-14) Bailligand, J. -L. U. -Longrois, D. , Simmons, W. W. et al.: Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1βand IFN-γ. Am. J. Physiol. 268:H1293-H1303, 1995.

• 43-15) Hansen, P. R. , Haunso, S.: Effects of nitric oxide synthase inhibition on myocardial capillary permeability and reactive hyperaemic response. Cardiovasc. Res. 29:862-866, 1995.
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• 43-16) Zweier, J. L. Wang, P. , Samouilov, S. , KupPusamy, P.: Enzyme-independent formation of nitric oxide in biological tissues. Nature Med. 1(8):804-809, 1995.

• 43-17) 中村知夫, 宮坂勝之:新生児遷延性肺高血圧症に対し NO吸入療法を施行した症例. 治療学 29(2):1392-1394, 1995.

• 43-18) 仁科かほる, 三川勝也, 志賀 真, 前川信博, 尾原秀史:急性呼吸窮迫症候群に対するNO吸入療法. 治療学 29(2):1395-1398, 1995.

• 43-19) Snell, G. I. , Salamonsen, R. F. Bergin, P. , Esmore, D. S. , Khan, S. , Williams, T. J.: Inhaled nitric oxide used as a bridge to heart-lung transplantation in a patient with end-stage pulmonary hepertension. Am. J. Respir. Crit. Care Med. 151:1263-1266, 1995.

• 43-20) Robbins, C. C. , Davis, J. N. Merritt, T. A. , Amirkhanian, J. D. , Sahgal, N. , Morin, F. C. III. Horowitz, S.: Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation. Am. J. Physiol. 269:L545-L550, 1995.

• 43-21) Kiff, R. J. , Moss, D. W. , Moncada, S.: Effect of nitric oxide gas on the generation of nitric oxide by isolated blood vessels: implication for inhalation therapy. Br. J. Pharmacol 113:496-498, 1994.
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• 43-22) Kharitonov, S. A. , Logan-Sinclair, R. B. , Busset, C. M. , Shinebourne, E. A.: Peak expiratory nitric oxide difference in men and women: relation to the menstrual cycle. Br. Heart J. 72:243-245, 1994.

• 43-23) Bauer, J. A. , Wald, J. A. , Doran, S. , Soda, D.: Endogenous nitric oxide in expired air: effects of acute exercise in human, Life Sci. 55(24):1903-1909, 1994.
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• 43-24) Kharitonov, S. A. , Robbins, R. A. , Yates, D. , Keatings, V.: Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am. J. Respir. Crit. Care Med. 152:609-612, 1995.
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• 43-25) Elsayed, N. M.: Toxicity of nitrogen dioxide: an introduction. Toxicol. 89:161-174, 1994.

• 43-26) Phelps, D. T. , Ferro, T. J. , Higgins, P. J. , Shankar, R. , Parker, D. M. , Johnson, A.: TNF-αinduces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C. Am. J. Physiol. 269:L551-L559, 1995.

• 43-27) White, A. C. , Maloney, E. K. , Boustani, M. R. , Hassoun, P. M. , Fanburg, B. L.: Nitric oxide increases cellular glutathione levels in rat lung fibroblasts. Am. J. Respir. Care Mol. Biol. 13:442-448, 1995.

• 43-28) Finder, J. , Stark, W. W. Jr. , Nakayama, D. K. , Geller, D. , Wasserloos, K. Pitt, B. R. , Davies, P.: TGF-βregulates production of NO in pulmonary artery smooth muscle cells by inhibiting expression of NOS. Am. J. Physiol. 268:L862-L867, 1995.

• 43-29) Belvisi, M. , Barnes, P. L. Larkin, S. , Yacoub, M. , Tadjkarimi, S. , Williams, T. J. , Mitchell, J. A.: Eur. J. Pharmacol. 283:255-258, 1995.

• 43-29a) Berisha, H. I. , Pakbaz, H. , Absood, A. , Said, S. I.: Nitric oxide as a mediator of oxidant lung injury due to paraquat. Proc. Natl. Acad. Sci. USA 91:7445-7449, 1994.

• 43-30) Shaul, P. W. , North, A. J. , Brannon, T. S. , Ujiie, K. , Wells, L. B. , Nisen, P. A. , Lowenstein, C. J. , Snyder, S. H. , Star, R. A.: Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung. Am. J. Respir. Cell Mol. Biol. 13:167-174, 1995.
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• 43-31) Ischiropoulos, H. , Al-Mehdi, A. B. , Fisher, A. B.: Reactive species in ischemic rat lung injury: contribution of peroxynitrite. Am. J. Physiol. 269:L158-L164, 1995.
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• 43-32) Lundberg, J. O. N. F. -Szallasi, T. , Weitzberg, E. Rinder, J. , Lidholm, J. , Anggard, A. H. , Hokfelt, T. , Lundberg, J. M. , Alving, K.: High nitric oxide production in human paranasal sinuses. Nature Med. 1(4):370-373, 1995.

• 43-33) Guo, F. H. , De Raeve, H. R. , Rice, T. W. , Stuehr, D. J. , Thunnissen, F. B. J. M. , Erzurum, S. C.: Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo. Proc. Natl. Acad. Sci. USA 92:7809-7813, 1995.

• 43-34) Greiff, L. Andersson, M. , Svensson, C. , Nilsson, M. , Erjefalt, I. , Erjefalt, J. S. , Persson, C. G. A.: Topical nitroprusside may reduce histamine-induced plasma exudation in human nasal airway. Allergy 50:593-597, 1995.

• 43-35) Kharitonov, S. A. , O'Connor, B. J. , Evans, D. J. , Barnes, P. J.: Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am. J. Respir. Crit. Care Med. 151:1894-1899, 1995.
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• 43-36) Yanaka, A. , Muto, H. , Fukutomi, H. , Ito, S. , Silen, W.: Role of nitric oxide in restitution of injured guinea pig gastric mucosa in vitro. Am. J. Physiol. 268:G933-G942, 1995.
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• 43-37) Stroff, T. , Lambrecht, N. , Peskar, B. M.: Nitric oxide as mediator of the gastroprotection by cholecytokinin-8 and pentagastrin, Eur. J. Pharmacol. 260:R1-R2, 1994.

• 43-38) Elliot, S. N. McKnight, W. , Cirino, G. , Wallace, J. L.: Anitric oxide-releasing non-steroidal anti-inflammatory drug accelerates gastric ulcer healing in rats. Gastroenterology 109:524-530, 1995.

• 43-39) Lefebre, R. A. , Smits, G. J. M. Timmermans, J. -P.: Study of NO and VIP as nonadrenergic non-cholinergic neurotransmitters in the pig gastric fundus. Br. J. Pharmacol. 116:2017-2026, 1995.

• 43-40) Gaginella, T. S. , Mascolo, N. , Izzo, A. A. , Autore, G. Capasso, F.: Nitric oxide as amediator of bisacodyl and phenolphthalein laxative addition. J. Pharmacol. and Expt. Therapeutics 270(3):1239-1245, 1994.

• 43-41) Robbons, K. A. , Zhang, X. -J. , Thompson, J. H. , Greenberg, S. S. , Moore, W. M. , Kornmeier, C. M. , Currie, M. G. , Lerche, N. , Blanchard, J. , Clark, D. A. , Miller, M. J. S.: Potential role of nitric oxide in a model of chronic colitis in rhesus macaques. Gastroenterology 108:705-711, 1995.

• 43-42) Barry, M. K. , Aloisi, J. D. , Pichering, S. P. , Yeo, C. J.: Nitric oxide modulates water and electrolyte transport in the ileum. Annals of Surgery 216(4):382-388, 1994.

• 43-43) De Man, J. G. , Boeckxstaens, G. E. De Winter, B. Y. , Moreels, T. G. , Misset, M. E. , Herman, A. G. , Pelckmans, P. A.: Comparison of the pharmacological profile of S-nitrosothiols, nitric oxide and the nitrergic neurotransmitter in the canine ileocolonic junction. Br. J. Pharmacol. 114:1179-1184, 1995.
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• 43-44) Raul, F. , Galluser, M. , Schleiffer, R. , Gosse, F. Hasselmann, M. , Seiler, N.: Beneficial effects of L-arginine on intestinal epithelial restitution after ischemic damage in rats. Digestion 56:400-405, 1994.

• 43-45) Wang, Y. , Mathews, W. R. , Guido, M. G. , Farhood, A. , Jaescheke, H.: Inhibition of nitric oxide synthesis aggravates reperfusion injury after hepatic ischemia and endotoxemia. Shock 4(4):282-288, 1995,

• 43-46) C. -Jimenez, M. , R. -Cabafiero, L. M. -Oterino, J. A. , L-Novoa, J. M. , S. -Rodriguez, A.: Nitric oxide production by mononuclear leukocytes in alcoholic cirrhosis. J. Mol. Med. 73:31-33, 1995.

• 43-47) Masini, E. Mugnai, L. Foschi, M. , Laffi, G. , Gentilini, P. , Mannainoi, P. F.: Int. Arch. Allergy Immunol. 107:197-198, 1995.

• 43-48) Wang, G. -S. , Liu, G. -T.: Role of nitric oxide in immunological liver damage in mice. Biochem. Pharmacol. 49(9):1277-1281, 1995.
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• 43-49) Nussler, A. K. , Di Silvio, M. , Liu, Z. -Z. , Geller, D. A. , Freeswick, P. , Dorko, K. , Bartoli, F. Billiar, T. R.: Further characterization and comparison of inducible nitric oxide synthase in mice, rat and human hepatocytes. Hepatology 21:1552-1560, 1995.
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• 43-50) Devlin, J. , Palmer, M. J. , Gonde, C. E. , O'Grady, J. , Heaton, N. , Tan, K. C. , Martin, J. F. Moncada, S. , Williams, R: Nitric oxide generation: Aprediction parameter of acute allograft rejection. Transplantation 58(5):592-595, 1994.

• 43-51) Hortelano, S. , Dewez, B. , Genaro, A. M. D. -Gnerra, J. M. , Bosca, L.: Nitric oxide is released in regenerating liver after partial hepatectomy. Hepatology 21:776-786, 1995.

• 43-52) Akabane, A. , Kato, I. , Takesawa, S. , Unno, M. , Yonekura, H. , Yoshimoto, T. , Okamoto, H: Nicotinamide inhibits IRF-1 mRNA induction and prevents IL-1β-induced nitric oxide synthase expression in pancreaticβcells. Biochem. Biophys. Res. Commun. 215(2):524-530, 1995.

• 43-53) Heller, B. , Wang, Z. -Q. , Wagner, E F. , Radons, J. , Burkle, A. , Fehsel, K. , Burkart, V. , Kolb, H.: Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J. Biol. Chem. 270(19):11176-11180, 1995.

• 43-54) Eizirk, D. L. Sandler, S. , Welsh, N. , C. -Cvrlje, M. , Nieman, A. , Geller, D. A. , Pipeleers, D. G. , Bendtzen, K. , Hellerstrom, C.: Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. J. Clin. Invest. 93:1968-1974, 1994.

• 43-55) Flodstrom, M. , Nieman, A. , Bedoya, F. J. , Morris, S. M. Jr. , Eizirik, D. L.: Expression of the citrulline-nitric oxide cycle in rodent and human pancreaticβ-cells. Endocrinol. 136(8):3200-3206, 19995.

• 43-56) Satoh, A. , Shimosegawa, T. , Abe, T. , Kikuchi, Y. , Abe, R. , Koizumi, M. , Toyota, T.: Role of nitric oxide in the pancreatic blood flow response to caerulein. Pancreas 9(5):574-579, 1994.
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• 43-57) Kaneto, H. , Fujii, J. , Seo, H. G. et al.: Apoptotic cell death triggered by nitric oxide in pancreaticβ-cells. Diabetes 44:733-738, 1995.

第44章 泌尿器, 生殖器・内分泌系でのNO

P.727 掲載の参考文献

• 44-1) Muhl, H. , Pfeilschifter, J.: Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1β-stimulated rat mesangial cells. J. Clin. Invest. 95:1941-1946, 1995.

• 44-2) Ashab, I. , Peer, G. , Blum, M. et al.: Oral administration of L-arginine and captopril in rats prevents chronic renal failure by nitric oxide production. Kidney Intl. 47:1515-1521, 1995.

• 44-3) Zhang, J. , Van Meel, J. C. A. , Pfaffendorf, M. Zhang, J. , Van Zwieten, P. A.: Endothelium-dependent nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta. Eur. J. Pharmacol. 262:247-253, 1994.

• 44-4) Conger, J. , Robinette, J. , Villar, A. , Raij, L. Shultz, P.: Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilators in postischemic acute renal failure. J. Clin. Invest. 76:631-638, 1995.

• 44-5) Myers, S. I. , Hernandez, R. , Castaneda, A.: Possible role for oxygen free radicals in the regulation of renal nitric oxide synthesis and blood flow. Am. J. of Surgery 169:604-608, 1995.

• 44-6) Sharma, K. Danoff, T. M. , DePiero, A. , Ziyadeh, F. N.: Enhanced expression of inducible nitric oxide synthase in murine macrophages and glomerular mesangial cells by elevated glucose levels. Biochem. Biophys. Res. Commun. 207(1):80-88, 1995.
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• 44-7) Ito, S. , Ren, Y.: Evidence for the role of nitric oxide in macula densa control of glomerular hemodynamics. J. Clin. Invest. 92:1093-1098, 1993.
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• 44-8) Kin, S. , Sasaki, T. , Gu, K. Nakayama, K. , Tamura, K. , Nakai, I. , Oka, T.: The cytoprotective role of nitric oxide in ischemia-reperfusion injury in the rat kidney. Transplantation Proc. 27(1):754-756, 1995.

• 44-9) Satake, N. Zhou, Q. , Shibata, S.: Inhibitory effect of sodium nitroprusside on the relaxing action of isoproterenal in isolated rat urinary bladder. Gen. Pharmac. 25 (4):739-745, 1994.

• 44-10) Ehren, I. , Hammarstrom, M. , Adolfsson, J. , Wiklund, N. P.: Induction of calciumdependent nitric oxide synthase by sex hormones in the guinea-pig urinary bladder. Acta Physiol. Scand. 153:393-394, 1995.
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• 44-11) Hull, E. M. , Lumley, L. A. , Matuszewich, L. Dominquez, J. , Moses, J. , Lorrain, D. S.: The role of nitric oxide in sexual function of male rats. Neuropharmacol. 33(11):1499-1504, 1994.

• 44-12) Melis, M. R. , Stancampiano, R. , Argiolas, A.: Role of nitric oxide in penile erection and yawning induced by 5-HT. , receptor agonists in male rats. Naunyn-Schmiedeberg's Arch. Pharmacol 351:439-445, 1995.

• 44-13) Carrier, S. , Hricak, H. , Lee, S. -S. et al.: Radiation-induced decrease in nitric oxide synthase-containing nerves in the rat penis. Radiology 195:95-99, 1995.
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• 44-14) Halcberg, G. , Kossenjans, W. , Miodovnik, M. , Myatt, L.: The interaction of nitric oxide and superoxide in the human fetal-placental vasculature. Am. J. Obstet. Gynecol 173:528-533, 1995.

• 44-15) Shukovski, L. Tsafriri, A.: The involvement of nitric oxide in the ovulatory process in the rat. Endocrinol. 135(5):2287-2290, 1994.

• 44-16) Mani, S. K. , Allen, J. M. C. Rettori, V. , McCann, S. M. O'Malley, B. W. , Clark, J. H.: Nitric oxide mediates sexual behavior in female rats. Proc. Natl. Acad. Sci. USA 91:6468-6472, 1994.

• 44-17) Rosselli, M. , Imthurn, B. , Keller, P. J. , Jackson, E. K. , Dubey, R. K.: Circulating nitric oxide levels in postmenopausal women substituted with 17β-estradiol and norethisterone acetate. Hypertension 25(Pt2): 848-853, 1995.

• 44-18) Weiner, C. P. , Lizasoain, I. , Baylis, S. A. , Knowles, R. C. Charles, I. G. Moncada, S.: Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc. Natl. Acad. Sci. USA 91:5212-5216, 1994.

• 44-19) Canteros, G. , Rettori, V. , Franchi, A. , Genaro, A. , Cebral, E. Faletti, A. , Gimero, M. , McCann, S. M.: Ethanol inhibits luteinizing hormone-releasing hormone (LHRH) secretion by blocking the response of LHRH neuronal terminals to nitric oxide. Proc. Natl. Acad. Sci. USA 92:3416-3420, 1995.

• 44-20) Hayashi, T. , Yamada, K. , Esaki, T. , Kuzuya, M. et al.: Estrogen increases endothelial nitric oxide by a receptor-mediated system. Biochem. Biophys. Res. Commun. 214(3):847-855, 1995.
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• 44-21) Ikeda, U. , Kanbe, T. , Nakayama, I. et al.: Aldosterone inhibits nitric oxide synthesis in rat vascular smooth muscle cells induced by interleukin-1β. Eur. J. Pharmacol. 290:69-73, 1995.

• 44-22) Aguila, M. C.: Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of granylate cyclase. Proc. Natl. Acad. Sci. USA 91:782-786, 1994.

• 44-23) Lloyd, R. V. , Jin, L. Qian, X. , Zhang, S. , Scheithauser, B. W.: Nitric oxide synthase in the human pituitary gland. Am. J. Pathol 146(1):86-94, 1995.

• 44-24) Star, R. A. , Rajora, N. , Huang, J. , Stock, R. C. , Catania, A. , Lipton, J. M.: Evidence of autocrine modulation of macrophage nitric oxide synthase byα-melanocytestimulating hormone. Proc. Natl. Acad. Sci. USA 92:8016-8020, 1995.

• 44-25) Vargas, F. , Montes, R. , Sabio, M. , G. -Estafi, J.: Role of nitric oxide in the systemic circulation of conscious hyper-and hypothyroid rats. Gen. Pharmacol. 25(5):887-891, 1994.

• 44-26) Oyanagui, Y.: Nitric oxide-and hydrogen peroxide-mediated gene expression by glucocorticoids and FK506 in histamine paw edema of mice. Life Sci. 55(9):PL177-PL185, 1994.

第45章 神経系でのNO

P.743 掲載の参考文献

• 45-1) Lipton, S. A. , Stamler, J. S.: Actions of redox-related congers of nitric oxide at the NMDA receptor. Neuropharmacol. 33 (11):1229-1233, 1994.

• 45-2) Culcasi, M. , L-Cazal, L. Pietri, S. , Bochaert, J.: Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons. J. Biol. Chem. 269(17):12589-12593, 1994.

• 45-3) Ohkuma, S. , Narihara, H. , Katsura, M. , Hasegawa, T. , Kuriyama, K.: Nitric oxide-induced [3H] GABA release from cerebral cortical neurons is mediated by peroxynitrite. J. of Neurochem. 65:1109-1114, 1995.
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• 45-4) Strasser, A. , McCarron, R. M. , Ishii, H. , Stanimirovic, D. , Spatz, M.: L-arginine induces dopamine release from the striatum in vivo. NeuroReport 5:2298-2300, 1994.

• 45-5) S. -Levine, Z. , Galron, R. , Sokolvsky, M.: Cyclic GMP formation in rat cerebellar slices is stimulated by endothelins via nitric oxide formation and by sarafotoxins via formation of carbon monoxide. Biochemistry 33:14656-14659, 1994.

• 45-6) Feinstein, D. L. , Galea, E. Cermak, J. , Chugh, P. , Lyandvert, L. , Reis, D. J.: Nitric oxide synthase expression in glial cells: suppression by tyrosine kinase inhibitors. J. Neurochem. 62:811-814, 1994.
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• 45-7) Habu, H. , Yokoi, L. Kabuto, H. , Mori, A.: Application of automated flow injection analysis to determine nitrite and nitrate in mouse brain. NeuroReport 5:1571-1573, 1994.

• 45-8) Dinerman, J. L. Dawson, T. M. , Schell, M. J. , Snowman, A. , Snyder, S. H.: Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implication for synaptic plasticity. Proc. Natl. Acad. Sci. USA 91:4214-4218, 1994.
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• 45-9) Zhang, F. , White, J. G. , Iadecala, C.: Nitric oxide donor increase blood flow and reduce brain damage in focal ischemia. J. Cerebral Flow and Metabol. 14(2):217-226, 1994.

• 45-9a) Dalkara, T. , Moskowitz, M. A.: The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia. Brain Pathol. 4:49-57, 1994.

• 45-10) Schmidt, K. , List, B. M. , Klatt, P. , Mayer, B.: Characterization of neuronal amino acid transporters: uptake of NOS inhibitors and implication for their biological effects. J. of Neurochem. 64:1469-1475, 1995.

• 45-11) Muhonen, M. G. , Heistad, D. D. , Faraci, F. M. , Loftus, C. M.: Augmentation of blood flow through cerebral collaterals by inhibitor of nitric oxide synthase. J. of Cerebral Blood Flow and Metabol. 14:704-714, 1994.

• 45-12) Rundfeldt, C. , Koch, R. , Richter, A. , Mevissen, M. , Gerecke, U. , LUscher, W.: Dose-dependent anticonvulsant and proconvulsant effects of nitric oxide synthase inhibitors on seizure threshold in a cortical stimulation model in rats. Eur. J. Pharmacol. 274:73-81, 1995.

• 45-13) Yokoi, I. , Kabuto, H. , Habu, H. , Inada, K. , Toma, J. , Mori. A.: Structure-activity relationship of arginine analogues on nitric oxide synthase activity in the rat brain. Neuropharmacol. 33(11):1261-1265, 1994.

• 45-14) Kelly, P. A. T. , Ritchie, I. M. , Arbuthnott, G. W.: Inhibitor of neuronal nitric oxide synthase by 7-nitroindazole. J. of Cerebral Blood Flow and Metabol. 15:766-773, 1995.

• 45-15) Dorheim, M. -A. , Tracey, W. R. Pollock, J. S. , Grammas, P.: Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease. Biochem. Biophys. Res. Commun. 205(1):659-665, 1994.
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• 45-16) Shukla, A. , Dikshit, M. , Srimal, R. C.: Nitric oxide modulates blood-brain barrier permeability during infections with an inactivated bacterium. NeuroReport 6:1629-1632, 1995.
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• 45-16a) Bonfoco, E. , Krainc, D. , Ankarcrona, M. , Nicotera, P. , Lipton, S. A.: Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl--D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA 92:7162-7166, 1995.
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• 45-17) Corasaniti, M. T. , Melino, G. , Navarra, M. , Garaci, E. F. -Agro, A. , Nistico, G.: Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase. Neurodegeneration 4:315-321, 1995.

• 45-18) Cleeter, M. W. J. , Cooper, J. M. , D. -Usmar, V. M. Moncada, S. , Schapira, A. H. V.: Reversible inhibitor of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. FEBS Letts. 345:50-54, 1994.

• 45-19) Lassen, L. H. , Thomsen, L. L. Olesen, J.: Histamine induces migraine via the HI-receptor. Support for the NO hypothesis of migraine. NeuroReport 6:1475-1479, 1995.

• 45-20) 岡田大助:学習, 記憶における NO の役割. 現代化学 4月:44-49, 1994.

• 45-21) Bernabeu, R. , Levi de Stein, M. , Fin, C. , Izquierdo, I. , Medina, J. H.: Role of hippocampal NO in the acquisition and consolidation of inhibitory avoidance learning. NeuroReport 6:1498-1500, 1995.

• 45-22) Marin, J. , Govantes, C.: Angiotensin-converting enzyme inhibitors and the role of nitric oxide and excitatory amino acids in improvement of cognition and memory. J. Autom. Pharmacol. 15:129-149, 1995.

• 45-23) Holscher, C. , Canevari, L. R. -Levin, G.: Inhibitors of PLA2 and NO synthase cooperate in producing amnesia of a spatial task. NeuroReport 6:730-732, 1995.

• 45-24) Richard, N. S. , Ng, K. T. , Gibbs, M. E.: Anitric oxide agonist stimulates consolidation of long-term memory in the 1-day-old chick. Behavioral Neurosci. 108(3):640-644, 1994

• 45-25) Robertson, J. D. , Bonaventura, J. , Kohm, A. P.: Nitric oxide is required for tactile learning in Octopzas vulgaris. Proc. R. Soc. Lond. B. 256:269-273, 1994.

• 45-26) Dzoljic, M. R. DeVries, R.: Nitric oxide synthase inhibitors reduces wakefulness. Neuropharmacol. 33(11):1505-1509, 1994.

• 45-27) Ohno, M. , Watanabe, S.: Nitric oxide synthase inhibitors block behavioral sensitization to methamphetamine in mice. Eur. J. Pharmacol. 275:39-44, 1995.
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• 45-28) Volke, V. , Koks, S. , Vasar, E. , Bourin, M. , Bradwejn, J. , Mannisto, P. T.: Inhibitor of nitric oxide synthase causes anxiolytic-like behaviour in an elevated plus-maze. NeuroReport 6:1285-1288, 1995

• 45-29) Masutani, H. , Nagai, K. , Nakagawa, H.: Possible involvement of nitric oxide in generation of circadian rhythm. Biol. Rhythm. Res. 25(4):433-441, 1994.

• 45-30) Hui, S. C. G. , Chan, T. -Y.: Mechanisms mediating NG-nitro-L-arginine methyl ester-induced hypophagia in mice. Eur. J. Pharmacol. 283:141-150, 1995

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第46章 NO測定法とNOSノックアウト・マウス

P.757 掲載の参考文献

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