書籍詳細

PART 1 臨床薬理編

P.20 掲載の参考文献

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• 2) Kapur S, Remington G: Dopamine D2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient. Biol Psychiatry 50:873-883, 2001
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• 3) Seeman P: Atypical antipsychotics: mechanism of action. Can J Psychiatry 47:27-38, 2002
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• 4) Garris PA, Wightman RM: Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex and striatum, an in vivo voltammetry study. J Neurosci 14:442-450, 1994

• 5) Strange PG: Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects. Pharmacol Rev 53:119-133, 2001
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• 6) Koepp MJ, Gunn RN, Lawrence AD et al: Evidence for striatal dopamine release during a video game. Nature 393:266-268, 1998
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• 7) Laruelle M, Abi-Dargham A, Gil R et al: Increased dopamine transmission in schizophrenia: Relationship to illness phases. Biol Psychiatry 46:56-72, 1999
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• 8) Seeman P, Tallerico T: Rapid release of antipsychotic drugs from dopamine D2 receptors: An explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine. Am J Psychiatry 156:876-884, 1999
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• 9) Farde L, Wiesel FA, Nordstroem A-L et al: D1 and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics. Psychopharmacolgy 99:S28-S31, 1989

• 10) Kapur S, Zipursky R, Jones C et al: A positron emission tomography study of quetiapine in schizophrenia-A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch Gen Psychiatry 57:553-559, 2000

• 11) Meltzer HY, Lee MA, Ranjan R et al: Relapse following clozapine withdrawal: effect of neuroleptic drugs and cyproheptadine. Psychopharmacology 124:176-187, 1996
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• 12) Csernansky JG, Mahmoud R, Brenner R: A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia. N Eng J Med 346:16-22, 2002

• 13) Ishikane T, Kusumi I, Matsubara R et al: Effects of serotonergic agents on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum. Eur J Pharmacol 321:163-169, 1997
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• 14) Seeman P, Kapur S: Schizophrenia: More dopamine, more D2 receptors. Proc Natl Acad Sci USA 97:7673-7675, 2000
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• 15) Abi-Dargham A, Rodenhiser J, Printz D et al: Increased baseline occupancy of D2 receptors by dopamine in schizophrenia. Proc Natl Acad Sci USA 97:8104-8109, 2000
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• 16) Kusumi I, Takahashi Y, Suzuki K et al: Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain. J Neural Transm 107:295-302, 2000

• 17) Kapur S: A new framework for investigating antipsychotic action in humans: Lessons from PET imaging. Mol Psychiatry 3:135-140, 1998
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• 18) Meltzer HY, Matsubara S, Lee J-C: Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J pharmacol Exp Ther 251 238-245, 1989
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• 19) Pietzcker A, Gaebel W, Kopcke W et al: Intermittent versus maintenance neuroleptic long-term treatment in schizophrenia:2 year results of a German multicenter study. J Psychiatr Res 27:321-339, 1993

• 20) Burris K, Molski TF, Xu C et al: Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther 302:381-389, 2002
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P.28 掲載の参考文献

• 1) Carlsson A, Lindquist M: Effect of chlorpromazine and haloperidol on formulation of 3-methoxytyramine and nometanephrine in mouse brain. Acta Pharmacol Toxicol 20:140-144, 1963

• 2) Seeman P: Brain dopamine receptors. Pharmachol Rev 32:229-313, 1980
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• 3) Peroutuka SJ, Snyder SH: Relationship of neuroleptic drug effects at brain dopamine, serotonin, α-adrenergic, and histamin receptors to clinical potency. Am J Psychiat 137:518-1552, 1980

• 4) Costall B, Fortune DH, Naylor RJ: Serotonergic involvement with neuroleptic catalepsy. Neuropharmacolgy 14:859-868, 1975

• 5) Lieberman JA, Mailman RB, Duncan G et al: Serotonergic basis of antipsychotic drug effects in schizophrenia. Biol Psuchiat 44:1099-1117, 1998
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• 6) Janssen PAJ: The development of new antipsychotic drugs: Towards a new strategy in the management Of Chronic psychoses. Jr Drug Ther Res 12:324-328, 1987

• 7) Kane J, Honingfeid G, Singer J et al: Clozapine for the treatment-resistant schizophrenia. Arch Gen Psychiat 45:789-796, 1988

• 8) Meltzer HY, Matsubara S, Lee J-C: Classification of typical and atypical antipsychotic drugs on the basis of dopamine D1, D2 and serotonin 2 pKi values. J Pharmacol EXp Ther 251 :238-246, 1989
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• 9) Matsubara S, Matsubara R, Kusumi I et al: Dopamine D1, D2 and serotonin 2 receptor occupancy by typical and atypical antipsychotic drugs in vivo J Pharmacol Exp Ther 265:498-508, 1993
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• 10) Stockmeier CA, DiCarlo JJ, Thompson P et al: Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy of serotonin 2 and dopamine 2 receptors. J Pharmacol Exp Ther 266:1374-1384, 1993

• 11) Nordstroem A-L, Farde L, Halldin C: High 5-HT2 receptor occupancy in clozapine treated patients demonstrated by PET. Psychopharmachol 110:365-367, 1993

• 12) Meltzer HY: The role of serotonin in antipsychotic drug action. Neuropsychopharmachol 21:106S-115S, 1999
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P.34 掲載の参考文献

• 1) Bantick RA, Deakin JFW, Grasby PM: The 5-HTIA receptor in schizophrenia: a promising target for novel atypical neuroleptics? J Psychopharmacology 15:37-46, 2001

• 2) Millan MJ: Improving the treatment of schizophrenia: focus on serotonin (5-HT)1A receptors. J Pharmacol Exp Ther:295:853 861, 2000

• 3) Bames NM, Sharp T: A review of central 5-HT receptors and their function. Neuropharmacology 38:1083-1152, 1999

• 4) Hashimoto T, Nishino N, Nakai H et al: Increase in serotonin 5-HT1A receptors in prefrontal and temporal cortices of brains from patients with chronic schizophrenia. Life Sci 48:355-363, 1991
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• 5) Joyce JN, Shane A, Lexow N et al: Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology 8:315-336, 1993
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• 6) Sumiyoshi , T Stockmeier CA, Overholser JC et al: Serotonin1A receptors are increased in postmertem prefrontal cortex in schizophrenia. Brain Res 708:209-214, 1996
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• 7) Simpson MDC, Lubman DI, Slater P et al: Autoradiography with [3H]8-OH-DPAT reveals increases in 5-HT1A receptors in ventral prefrontal cortex in schizophrenia. Biol Psychiatry 39:919-928, 1996

• 8) Bumet PWJ, Eastwood SL, Harrison PJ:5-HT1A and 5-HT2A receptor mRNAs and binding sites are differentially altered in schizophrenia. Neuropsychopharmacology 15:442-455, 1996

• 9) Burnet PWJ, Eastwood SL, Harrison PJ:[3H] WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with[3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia. Neurochem Int 30:565-574, 1997

• 10) Gurevich EV, Joyce JN: Alterations in the cortical serotonergic system in schizophrenia: a postmortem study. Biol Psychiatry 42:529-545, 1997
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• 11) Slater P, Doyle CA, Deakin JFW: Abnormal persistence of cerebellar serotonin-1A receptors in schizophrenia suggests failure to regress in neonates. J Neural Transm 1105:305-315, 1998

• 12) Dean B, Tomaskovic-Crook E, Opeskin K et al: No change in the density of the serotonin1A receptor, the serotonin4 receptor or the serotonin transporter in the dorsolateral prefrontal cortex from subjects with schizophrenia. Neurochem Int 34:109-115, 1999
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• 13) Tauscher J, Kapur S, Verhoeff PLG et al: Brain serotonin 5-HTIA receptor binding in schizophrenia measured by positron emission tomography and [11C] WAY-100635. Arch Gen Psychiatry 59:514-520, 2002

• 14) Newman-Tancredi A, Chaput C, Verriele L et al: Clozapine is a partial agonist at cloned, human serotonin 5-HTIA receptors. Neuropharmacology 35:119-121, 1996

• 15) Rollema H, Lu Y, Schmidt AW et al: Clozapine increases dopamine release in prefrontal cortex by 5-HTIA receptor activation. Eur J Pharmacology 338: R3-R5, 1997

• 16) Rollema H, Lu Y, Schmidt AW et al:5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex. Biol Psychiatry 48:229-237, 2000

• 17) Seeger TF, Seymour PA, Schmidt AW et at: Ziprasidone (CP-88, 059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. J Pharmacol Exp Ther 275:101-113, 1995
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• 18) Assie M-B, Cosi C, Koek W: 5-HT1A receptor agonist properties of the antipsychotic, nemonapride: comparison with bromeguride and clozapine. Eur J Pharmacology 334:141-147, 1997
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• 19) Newman-Tancredi A, Gavaudan S, Conte C et al: Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a[35S]GTPySbinding study. Eur J Pharmacology 355:245-256, 1998
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• 20) Elliott J, Reynolds GP: Agonist-stimulated GTPy[35S]binding to 5-HT1A receptors in human post-mortem brain. Eur J Pharmacology 386:313-315, 1999

• 21) Cosi C, Koek W: The putative<silent>5-HT1A receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT1A receptors. Eur J Pharmacology 401 :9-15, 2000

• 22) Cosi C, Koek W: Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT1A receptors expressed in HeLa cells. Eur J Pharmacology 433:55-62, 2001

• 23) Schmidt AW, Lebel LA, Howard HR Jr et al: Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile. Eur J Pharmacology 425:197-201, 2001
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• 24) Newman-Tancredi A, Verriele L, Millan MJ: Differential modulation by GTPyS of agonist and inverse agonist binding to h5-HT1A receptors revealed by[3H]WAY . Brit J Pharmacology 132:518-524, 2001

• 25) Newman-Tancredi A, Verriele L, Touzard M et al: Efficacy of antipsychotic agents at human 5-HTIA receptors determined by[3H]WAY 100,635 binding affinity ratios: relationship to efficacy for G-protein activation. Eur J Pharmacology 428:177-184, 2001

• 26) Jordan S, Koprivica V, Chen R et al: The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor. Eur J Pharmacology 441:137-140, 2002
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• 27) Sovner R, Pamell-Sover N: Use of buspirone in the treatment of schizophrenia. J Clin Psychopharmacology 9 61-62, 1989

• 28) D'Mello DA, McNeil JA, Harris W: Buspirone suppression of neuroleptic-induced akathisia: multiple case reports. J Clin Psychopharmacology 9:151-152, 1989

• 29) Brody D, Adler LA, Kim T et al: Effects of buspirone in seven schizophrenic subjects. J Clin Psychopharmacology 10:68-69, 1990

• 30) Goff DC, Midha KK, Brotman AW et al: An open trial of buspirone added to neuroleptics in schizophrenic patients. J Clin Psychopharmacology 11:193-197, 1991

• 31) Pantelis C, Bames TRE: Acute exacerbation of psychosis with buspirone? J Psychopharmacology 7:295-300, 1993

• 32) Decina P, Mukherjee S, Bocola V et al: Adjunctive trazodone in the treatment of negative symptoms of schizophrenia. Hosp Commun Psychiatry: y 45:1220 1223, 1994

• 33) Sumiyoshi T, Matsui M, Yamashita I et al: Effect of adjunctive treatment with serotonin-1A agonist tandospirone on memory functions in schizophrenia. J Clin Psychopharmacologyy 20 386-388, 2000

• 34) Sumiyoshi T, Matsui M, Yamashita I et al: The effect of tandospirone, a serotonin1A agonist, on memory function in schizophrenia. Biol Psychiatry 49:861-868, 2001
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• 35) Sumiyoshi T, Matsui M, Nohara S et al: Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment. Am J Psychiatry 158:1722-1725, 2001
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• 36) Sirota P, Epstein B, Benatov R et al: An open study of buspirone augmentation of neuroleptics in patients with schizophrenia. J Clin Psyhopharmacology 21:454-455, 2001

• 37) Berk M, Ichim C, Brook S: Efficacy of mirtazapine add on therapy to haloperidol in the treatment of the negative symptoms of schizophrenia: a doubleblind randomized placebo-controlled study. Int Clin Psychopharmacology 16:87-92, 2001

• 38) Caspi N, Modai I, Barak P et al: Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study. Int Clin Psychopharmacology 16:111-115, 2001

• 39) Gobert A, Rivet J-M, Audinot V et al: Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto-and heteroreceptor-mediated control of release. Neuroscience 84:413-429, 1998
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• 40) Friedma JI, Temporini H, Davis KL: Pharmacologic strategies for augmenting cognitive performance in schizophrenia. Biol Psychiatry 45:1-16, 1999

P.43 掲載の参考文献

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• 3) Mannens G, Huang ML, Meuldermans W et al: Absorption, metabolism, and excretion of risperidone in humans. Drug Metab Dispos 21:1134-1141. 1993
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• 4) Olesen OV, Licht RW, Thomsen E et al: Serum concentrations and side effects in psychiatric patients during risperidone therapy. Ther Drug Monit 20:380-384, 1998
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• 5) Scordo MG, Spina E, Facciola G et al: Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone. Psychopharmacology (Berl) 147:300-305, 1999
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• 6) Bork JA, Rogers T, Wedlund PJ et al: A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A. J Clin Psychiatry 60:469-476, 1999

• 7) Huang ML, Van Peer A, Woestenborghs R et al: Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects. Clin Pharmacol Ther 54:257-268, 1993
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• 8) Johansson I, Oscarson M, Yue Q et al: Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol Pharmacol 46:452 459, 1994

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• 10) Roh HK, Kim CE, Chung WG et al: Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients. Eur J Clin Pharmacol 57:671-675, 2001
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• 11) Spina E, Scordo MG, Avenoso A et al: Adverse drug interaction between risperidone and carbamazepine in a patient with chronic schizophrenia and deficient CYP2D6 activity. J Clin Psychopharmacol 21:108-109, 2001

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• 13) Yasui-Furukori N, Hidestrand M, Spina E et al: Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes. Drug Metab Dispos 29:1263-1268, 2001
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• 14) Chong SA, Remington G: Clozapine Augmentation: Safety and Efficacy. Schizophr Bull 26:421-440, 2000
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• 16) Kronig MH, Munne RA, Szymanski S et al: Plasma clozapine levels and clinical response for treatment-refractory schizophrenic patients. Am J Psychiatry 152:179-182, 1995
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• 17) Hasegawa M, Gutierrez-Esteinou R, Way L et al: Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: effect of smoking. J Clin Psychopharmacol 13:383-390, 1993
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• 18) VanderZwaag C, McGee M, McEvoy JP et al: Response of patients with treatment-refractory schizophrenia to clozapine within three serum level ranges. Am J Psychiatry 153:1579-1584, 1996
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• 19) Narendran R, Young CM, Pristach CA et al: Efficacy of clozapine in the treatment of atypical antipsychotic refractory schizophrenia: a pilot study. J Clin Psychopharmacol 23:103-104, 2003
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• 20) Henning U, Loffler S, Krieger K et al: Uptake of clozapine into HL-60 promyelocyclic leukaemia cells. Pharmacopsychiatry 35:90-95, 2002
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• 21) Freeman DJ, Oyewumi LK: Will routine therapeutic drug monitoring have a place in clozapine therapy? Clin Pharmacokinet 32:93-100, 1997
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• 22) Detting M, Sachse C, Muller-Oerlinghausen B et al : Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes. Pharmacopsychiatry 33:218-220, 2000

• 23) Bredbacka PE, Paukkala E, Koponen H: Can severe cardiorespiratory dysregulation induced by clozapine monotherapy be predicted? Int Clin Psychoparmacol 8:205-206, 1993
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• 24) Chong SA, Tan CH, Lee HS: Hoading and clozapine-risperidone combination. (letter) J Clin Psychiatry 41:315-316, 1996

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• 33) Perry PJ, Lund BC, Sanger T et al: Olanzapine plasma concentrations and clinical response: acute phase results of the North American Olanzapine Trial. J Clin Psychopharmacol 21:14-20, 2001

• 34) Ellingrod VL, Perry PJ, Lund BC et al:5HT2A and 5HT2c receptor polymorphisms and predicting clinical response to olanzapine in schizophrenia. J Clin Psychopharmacol 22:622-624, 2002
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• 35) Skogh E, Reis M, Dahl ML et al: Therapeutic drug monitoring data on olanzapine and its N-demethyl metabolite in the naturalistic clinical setting. Ther Drug Monit 24:518-526, 2002
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• 36) Prior TI, Chue PS, Tibbo P et al: Drug metabolism and atypical antipsychotics. Eur Neuropsychopharmacol 9:301-309, 1999
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• 37) Savasi I, Millson RC, Owen JA: Quetiapine blood level variability. Can J Psychiatry 47:94, 2002
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• 38) DeVane CL, Nemeroff CB: Clinical pharmacokinetics of quetiapine: an atypical antipsychotic. Clin Pharmacokinet 40:509-522, 2001
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• 39) 藤本恵一, 水野佳子, 金丸博也: SM-9018の代謝物の検索と同定. 基礎と臨床 31:581-657, 1997

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• 41) 広兼元太, 染矢俊幸, 柴崎守和ほか: プロムペリドール代謝の個体差と臨床症状改善度との関連. 神経精神薬理 19:39-49, 1997

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• 46) 染矢俊幸, 広兼元太, 高橋三郎ほか: ハロペリドール代謝の個体差と臨床症状改善度との関連. 神経精神薬理 18:511-519, 1996

• 47) 染矢俊幸, 鈴木雄太郎: 【分裂病の治療ガイドライン】分裂病の薬物療法, 薬物療法アルゴリズムと治療の実際, 抗精神病薬治療におけるTDMの有用性と問題点. 精神科治療学15 (増刊):169-174, 2000

PART 2 治療編

P.52 掲載の参考文献

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• 3) Geddes J, Freemantle N, Harison P et al: A typical antipsychotics in the treatment of schizophrenia: Systematic overview and meta-regression analysis. Br Med J 321:1371-1376, 2000

• 4) Waraich PS, Adams CE, Roque M et at: Haloperidol dose for the acute phase of schizophrenia (Cochrane Review). In: The Cochrane Library, Issue 1, 2003. Oxford: Update Software.

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• 6) De Haan L, Van Bruggen M, Lavalaye J et al: Subjective experience and D2 receptor occupancy in patients with recent-onset schizophrenia treated with low-dose olanzapine or haloperidol: a randomized, double-blind study. Am J Psychiatry 160:303-309, 2003
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P.60 掲載の参考文献

• 1) Kane JM, Honigfeld G, Singer J et al: Clozapine for the treatment-resistant schizophrenia. Arch Gen Psych 45:789-796, 1988

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PART 3 新規抗精神病薬を用いた臨床例

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• 2) 上田均, 及川暁, 酒井明夫: 急性期における使い分け. 臨床精神薬理 5:1027-1035, 2002

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• 4) 大下隆司: 急性期精神病患者へのアプローチ. 臨床精神薬理5 (増刊):311-321, 2002

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• 2) 定永恒明, 定永史子, 八尾博史: 向精神薬と心電図QTc時間延長もしくはTorsades de pointesについて. 精神医学 43:921-921, 2001

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PART 4 治療上の注意点

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• 54) 村崎光邦, 小山司, 町山幸輝ほか: 新規抗精神病薬塩酸perospironeの精神分裂病に対する臨床評価-haloperidolを対照薬とした第III相試験. 臨床評価 24:159-205, 1997

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• 58) 鈴木健文, 高野晴成, 渡邊衡一郎ほか: 精神病薬の多剤併用大量療法への対応ガイドライン. 臨床精神薬理 4:1423-1430, 2001

• 59) 上田均, 酒井明夫: 従来型抗精神病薬からrisperidoneへの切り換え: その4. 臨床精神薬理 4:1709-1721, 2001

• 60) Weiden PJ, Aquila R, Dalheim L et al: Switching antipsychotic medications. J Clin Psychiatry 58 (Suppl 10):63-72, 1997

• 61) Weiden PJ, Aquila R, Emanuel M et al: Long-term considerations after switching antipsychotics. J Clin PSychiatry 59 (Suppl 19):36-49, 1998

• 62) 宮本歩, 長尾喜代治, 長尾喜一郎ほか: 精神分裂病患者におけるrisperidoneからquetiapineへの切り替えについて. 臨床精神薬理 4:1433-1440, 2001

• 63) 伊藤雅之, 丹羽真一, 松本出: 精神分裂病患者におけるrisperidoneからolanzapineへの切り替え -Quality of lifeの向上を目指して. 臨床精神薬理5 (増刊):415-426, 2002

• 64) 宮本歩, 山田恒, 長尾喜代治ほか: 従来型抗精神病薬からquetiapineへの切り替えについて. 臨床精神薬理 5:71-80, 2002

• 65) 宮本歩: 精神分裂病患者におけるquetiapine 24週間投与と経過観察. 臨床精神薬理 5:1127-1145, 2002

• 66) 岩崎剛士, 丹羽真一, 松本出: 統合失調症患者におけるrisperidoneからquetiapineへの2段階増量法による切り替え. 臨床精神薬理6:593-603, 2003

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• 68) 宮本聖也, 青葉安里: 抗精神病薬の新薬開発の未来. 月刊薬事 44:57-62, 2002

P.170 掲載の参考文献

• 1) 石郷岡純: 生涯薬物 (抗精神病薬) 療法, 新世紀の精神科治療1統合失調症の診療学, 岡崎祐士編, 中山書店, 東京, 2002, pp. 275-287

• 2) 石郷岡純: 新規抗精神病医薬の開発の歴史と今後の動向. 脳の科学 25:425-436, 2003

• 3) 石郷岡純: 単剤療法 (monotherapy) からskilful polypharmacyへ. Schizophrenia Frontiet:2:234-238, 2001

• 4) 石郷岡純, 吉岡正哉: 精神分裂病におけるQOL (quality of life) の改善をめざした薬物療法. 臨床精神薬理 5:3-13, 2002

• 5) 藤井康男: 21世紀の抗精神病薬療法-Olanzapine vs risperidone. 臨床精神薬理 4:1103-1110, 2001

• 6) 宮本聖也, 大木美香: 抗精神病薬の選択と多剤併用. 臨床精神薬理 5:843-854, 2002

• 7) Lambert T: 共通の治療目標: 抗精神病薬の切り替え. 臨床精神薬理 5:465-472, 2002

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PART 5 安全性とQOL

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• 17) 中根允文, 田崎美弥子, 宮岡悦良: 一般人口におけるQOLスコアの分布-WHOQOLを利用して-, 医療と社会 9:123-131, 1999

• 18) 宮田量治, 藤井康男 (訳): クオリティ・オブ・ライフ評価尺度-解説と利用の手引, 星和書店, 東京, 1995

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• 8) Simpson MM, Goetz RR, Devlin MJ et al: Weight gain and antipsychotic medication: differences between antipsychotic-free and treatment periods. J Clin Psychiatry 62:694-700, 2001
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