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未契約
書籍名 Evidenceに基づく急性白血病・リンパ腫診療マニュアル
出版社 日本医学館
発行日 2004-04-15
著者
  • 平井久丸(編集)
  • 神田善伸(執筆)
  • 伊豆津宏二(執筆)
ISBN 4890445536
ページ数
版刷巻号 第1版第1刷
分野
  • 臨床医学:内科
  • 血液
閲覧制限 未契約

執筆者の背景を反映し、本書からは強く現場の生のメッセージが伝わってくる。一方、evidenceに基づいた基本的な知識が、幅広くきわめて的確に紹介されている。臨床血液学の初学習のマニュアルとして、非常に完成度の高い優れたのに仕上がっており、血液内科の病棟における必携の書である。

目次

  • 表紙
  • 本書の刊行に寄せて
  • 目次
  • [1] 造血器腫瘍の診療総論
    • [1][1.] 造血器腫瘍の診療一般事項
      • A. 身体所見
      • B. 血算
      • C. 骨髄穿刺
      • D. 腫瘍細胞の由来を同定するための検査
        • 表1-1 CD分類
        • 表1-2 造血器腫瘍と染色体転座
      • E. 全身状態, 臓器評価
      • F. 感染症関連の検査
      • G. その他の検査
    • [1][2.] 造血器腫瘍の補助療法
      • A. 易感染状態 (好中球減少, 免疫不全状態) に対して
        • 表1-3 各抗細菌性抗菌薬による細菌感染症予防の特徴
      • B. その他の化学療法開始後早期の合併症対策
      • C. 好中球減少時の発熱に際して
      • D. 血小板減少時の対応
      • E. 貧血
      • F. 月経
      • G. 後期合併症
    • [1][3.] 造血器腫瘍に対して用いられる抗がん剤
      • A. 細胞周期
      • B. 造血器腫瘍に対して投与される抗がん剤
        • 表1-4 造血器腫瘍に対して投与される抗がん剤
        • 表1-5 血液悪性腫瘍に用いられる主な抗がん剤の作用と副作用
    • [1][4.] 化学療法の考え方
    • [1][5.] Evidence-based medicine (EBM) と統計学
      • A. Evidence-based medicineとは
      • B. 基本的な統計用語
      • 文献
  • [2] 急性白血病の診療
    P.49閲覧
    • [2][1.] 急性白血病の化学療法一般事項
      • 表2-1 AML subtypeのFAB分類の目安
      • 表2-2 正常細胞と急性白血病細胞の染色性
    • [2][2.] 急性骨髄性白血病 (AML)
      • A. 基本概念
        • 表2-3 急性骨髄性白血病に対する化学療法の成績
      • B. 大量cytarabine療法
      • C. Idarubicinの導入
      • D. 造血幹細胞移植の併用
        • 表2-4 第一寛解期急性骨髄性白血病に対する同種・自家骨髄移植と化学療法との比較
      • E. 解決されていない問題点
        • 表2-5 染色体分析によるAMLの予後予期
      • F. 化学療法の実際
    • [2][3.] 急性骨髄球性白血病 (AML-M3)
      • A. 基本概念
      • B. 化学療法の実際
    • [2][4.] 急性リンパ性白血病 (ALL)
      • A. 基本概念
        • 表2-6 ALLに対する化学療法の臨床試験
      • B. 化学療法成績改善のための試み
        • 表2-7 急性リンパ性白血病に対する同種・自家骨髄移植と化学療法との比較
      • C. 予後因子と造血幹細胞移植の適応
      • D. 化学療法の実際
    • [2][5.] 細胞表面免疫グロブリン陽性ALL (B-ALL)
      • A. 基本概念
      • B. 化学療法の実際
      • 文献
  • [3] リンパ腫の診療
    P.95閲覧
    • [3][1.] リンパ腫の診療一般事項
      • A. リンパ節生検
        • 表3-1 WHOの分類の主な疾患 (本書に登場する略称をまとめた)
      • B. 診断の確定と治療方針の決定
      • C. ステージング (病期分類の決定)
        • 表3-2 ステージングに必要な検査
        • 表3-3 リンパ腫の病期分類
      • D. それ以外の検査
      • E. 患者への説明
      • F. 治療後の効果判定
        • 表3-4 治療後の効果判定基準
      • G. Clinical trialにおけるendpoint
        • 表3-5 生存時間解析におけるendpoint
      • 文献
    • [3][2.] Aggressive lymphoma
      • A. 診断のポイント
      • B. Aggressive lymphomaの予後因子
        • 表3-6 IPIごとのCR率, 5年生存率
      • C. 初回治療
      • D. 再発・治療抵抗性aggressive lymphomaの治療 (サルベージ療法)
        • 表3-7 Aggressive lymphomaに対する主なサルベージ治療
      • E. 大量化学療法・自家造血細胞移植 (ASCT)
      • 文献
    • [3][3.] Indolent lymphoma
      • A. 診断のポイント
      • B. Follicular lymphoma (FL) の予後因子
        • 表3-8 FL再発後の予後
      • C. Indolent lymphoma (FL) の治療
      • D. Watch & Waitと化学療法
      • E. 抗CD20抗体 : Rituximab
      • F. プリン誘導体
      • G. 大量化学療法・自家造血幹細胞移植 (ASCT)
      • H. その他
      • 文献
    • [3][4.] ホジキンリンパ腫
      • A. 概要と診断のポイント
      • B. 標準治療
        • 表3-9 ホジキンリンパ腫に対する科学療法
      • C. 進行期ホジキンリンパ腫の予後予測モデル
      • D. 再発例に対する救援治療
      • E. 長期の治療関連合併症
      • 文献
    • [3][5.] 特殊な病型のリンパ腫
      • A. Lymphoblastic lymphoma (LBL)
      • B. Mantle cell lymphoma (MCL)
      • C. Burkittリンパ腫 (BL)
      • D. Mediastinal larage B-cell lymphoma (MLBCL)
      • E. Primary CNS lymphoma
      • F. 胃MALT lymphoma
      • G. Anaplastic large cell lymphoma (ALCL)
      • H. Extranodal NK / T lymphoma
      • 文献
  • 索引
    P.175閲覧
  • 奥付

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[3] リンパ腫の診療

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P.172 掲載の参考文献

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